Related by context. All words. (Click for frequent words.) 74 NF kB pathway 73 specific lectin receptors 72 hedgehog pathway 72 FGFs 71 EGF receptor 71 anti angiogenic drugs 70 VEGF receptor 70 Cathepsin B 70 IGF 1R 70 KRAS oncogene 70 hormone gastrin 70 cytolytic 69 histone deacetylase HDAC 69 MAPK pathway 69 intracellular signaling pathways 69 c MET 69 histone deacetylases 69 pro angiogenic 69 inhibit angiogenesis 69 antibody mediated 69 HCV replication 69 cellular pathways 69 anticancer therapies 69 TNFα 69 EGFR protein 69 Hedgehog signaling 69 PI3K Akt 68 EGFr 68 cathepsins 68 cytoprotective 68 molecularly targeted 68 osteoclast activity 68 SIRT1 enzyme 68 Treg cell 68 COX enzymes 68 biologic pathways 68 inhibit viral replication 68 aT cell 68 FGFR1 68 p# MAPK 68 LRP5 68 protein tyrosine phosphatases 68 A3 adenosine receptor 68 thromboxane A2 68 RAS RAF MEK 68 Wnt signaling pathway 68 EGFR inhibitors 68 neurite outgrowth 68 mTOR kinase 68 cMET 68 Smac mimetic 68 antiangiogenesis 68 anticancer therapy 67 BRAF inhibitors 67 biologic pathway 67 COX2 67 PI3K AKT 67 pleiotropic 67 oncogenesis 67 apoptotic pathway 67 intracellular signaling 67 inhibit EGFR 67 VEGF vascular endothelial 67 Smoothened 67 Enzastaurin 67 Akt activation 67 thymidylate synthase 67 ERK1 2 67 membrane receptors 67 plasminogen 67 mTOR inhibitors 67 tumor vasculature 67 PDGFR 67 FLT3 67 PPARg 67 mTOR mammalian target 67 PDGF receptor 67 molecular biomarkers 67 proto oncogene 67 E#F# 67 Symadex 67 antiangiogenic 66 p# activation 66 Notch pathway 66 chemokine receptor 66 p# MAP kinase 66 granzyme B 66 TGF beta pathway 66 K ras mutations 66 HDAC2 66 abnormal p# 66 immune modulatory 66 protein tyrosine phosphatase 1B 66 cAMP signaling 66 SIRT1 gene 66 DNA methyltransferases 66 AT1R 66 intracellular pathways 66 ERK pathway 66 fibrotic disease 66 FGFR 66 imatinib Gleevec 66 NKG2D 66 PI3K/mTOR 66 RANK ligand 66 costimulatory 66 downstream effectors 66 kidney urologic 66 alpha#beta# integrin 66 pDCs 66 Flt3 66 breast cancer metastasis 66 cytostatic 66 mTOR pathway 66 c MYC 66 tyrosine kinase inhibitors 66 antitumor 66 inhibiting tumor 66 tumor subtypes 66 selective inhibition 66 γ secretase 66 cyclin dependent kinases 66 lymphotoxin 66 EphA2 66 HER2 receptor 66 BCR ABL 66 tyrosine kinase receptor 66 antimitotic 66 plasma kallikrein 66 HER2 overexpression 66 NFkappaB 66 PTP 1B 66 PI3K pathway 66 preclinically 66 Androgen receptor 66 neurotrophic 66 coagulation cascade 66 NF kappaB 66 Immunohistochemical analysis 66 alpha folate receptor 65 gefitinib Iressa 65 tubulin binding 65 MEK ERK 65 dasatinib Sprycel 65 inflammatory cytokine 65 IGFBP2 65 aberrantly activated 65 Cytotoxic T 65 GSK3B 65 investigational humanized monoclonal antibody 65 RANK Ligand 65 erlotinib Tarceva 65 Wnt pathway 65 PI3 kinase 65 c myc 65 tumorigenesis 65 thymidylate synthase TS 65 FGFR2 65 CaM kinase II 65 TNFalpha 65 T#I [002] 65 PARP inhibition 65 glucagon receptor 65 HCV protease 65 antiproliferative effects 65 synovial cells 65 RAS pathway 65 IL 1β 65 Gleevec resistant 65 cyclooxygenase 2 65 IGF IR 65 vWF 65 beta1 integrin 65 Src kinase 65 metabotropic glutamate receptors 65 epithelial tumors 65 investigational therapies 65 TLE3 65 multi kinase inhibitor 65 factor HGF 65 EGFR receptor 65 BCR ABL protein 65 NF κB 65 MAGE A3 ASCI 65 immune modulating 65 tumor angiogenesis 65 neuroinflammatory 65 bacterial enzyme 65 ENMD # 65 humoral 65 acetylcholine receptor 65 LSD1 65 TNF α 65 VEGF pathway 65 Notch1 65 EGFR tyrosine kinase inhibitors 65 androgen receptor AR 65 TGF b 65 molecular abnormalities 65 cyclic AMP cAMP 65 NFkB 65 secretory pathway 65 intracellular pathogens 65 FOXO3a 65 chimeric monoclonal antibody 65 mitochondrial toxicity 65 primary cilia 65 tumor microenvironment 65 oncomodulin 65 phosphate S1P 65 demonstrated anti amnesic 65 CCR3 65 TGF beta signaling 65 WNT pathway 65 serine proteases 65 apoptosis inducing 65 Protein Kinase C 65 TNFa 65 TGF β 65 p# pathway 65 integrin receptors 65 JAK2 enzyme 65 cyclooxygenase 65 ADAM# 65 Bcr Abl 65 peptide antigens 65 neuro protective 65 tyrosine kinase 65 DHFR 65 cathepsin K 65 MAP kinase 65 JAK3 65 CTLA 4 65 Galectins 65 aromatase 65 TAp# 65 Smac mimetics 65 immunoregulatory 65 oncogenic transformation 64 WT1 64 TTR gene 64 Lyn kinase 64 chemosensitivity 64 chemopreventive agent 64 Akt3 64 activin 64 leukotriene pathway 64 HER2 gene 64 antimetastatic 64 inhibiting enzymes 64 EGF receptors 64 c myc gene 64 Stat5 64 anti CD3 64 B7 H3 64 cisplatin resistant 64 receptor tyrosine kinase 64 IAP inhibitor 64 renal fibrosis 64 immunomodulatory 64 PDGF alpha receptor 64 Hedgehog pathway 64 ALK inhibitors 64 epigenetic therapies 64 novel anticancer 64 epigenetic mechanisms 64 tyrosine phosphorylation 64 oncoprotein 64 GRNOPC1 contains 64 eIF 4E 64 vascular disrupting agents 64 glucocorticoid receptors 64 p# Shc 64 thyroid hormone receptor 64 potent antiproliferative 64 tyrosine kinase inhibitor 64 tumor antigen 64 oncogenic 64 androgen receptor signaling 64 ERK signaling 64 neuromuscular junction 64 MIF protein 64 microtubule targeting 64 potent cytotoxic 64 PKC isoforms 64 Bcl xL 64 cell signaling pathway 64 cell signaling pathways 64 cellular metabolism 64 IFN γ 64 HER3 64 gastrin 64 GSK3 64 diagnostic biomarkers 64 LRP6 64 endoplasmic reticulum stress 64 suppresses tumor 64 signaling cascades 64 DNA demethylation 64 mTOR signaling pathway 64 CCL# 64 antitumor immune 64 PIK3CA 64 Sphingomab 64 γδ T cells 64 allergic inflammation 64 tumor metastasis 64 CXCR4 receptor 64 uPA 64 M2 subunit 64 immune modulation 64 Ras pathway 64 VEGF signaling 64 potent inhibitors 64 factor Xa 64 adipogenic 64 tenascin C 64 uric acid lowering 64 immunomodulation 64 CCR2 64 p#/CBP 64 CYT# potent vascular disrupting 64 antiangiogenic activity 64 ADAMTS# 64 oncogenic signaling 64 kinase inhibition 64 mTOR signaling 64 NSCLC tumors 64 gastric carcinogenesis 64 NF kappaB activation 64 potent anticancer 64 anti fibrotic 64 intracellular protein 64 4E BP1 64 effector function 64 pRb 64 neuroprotectant 64 dephosphorylation 64 mda 7 64 basophils 64 insulin sensitizing 64 CA4P 64 cell lysis 64 renin angiotensin aldosterone 64 SERMs 64 TPO receptor 64 mucosal immunity 64 fusion enhancers 64 chemoresistance 64 bone morphogenetic proteins 64 epithelial cancers 64 MMP9 64 selectively inhibited 64 antitumor effect 64 Upregulation 64 PKC alpha 64 PTP1B 64 uPAR 64 Src kinases 64 telomerase inhibition 64 PPARγ 64 tumor necrosis 64 angiogenesis inhibitor 64 effector functions 64 cytokine signaling 64 upregulating 64 osteoclast 64 STAT3 signaling 64 thrombin receptor 64 virulence genes 64 mitogen activated protein kinases 64 Vascular endothelial growth 64 gastrointestinal stromal tumors GISTs 64 hedgehog signaling 64 monoclonal antibody mAb 64 superantigens 64 serotonin receptor 64 PPAR alpha 64 matrix metalloproteinases 64 TSLP 64 proteasome inhibitor 63 micro RNAs 63 p# mutations 63 oral kinase inhibitor 63 leukemic cell 63 pharmacokinetic interactions 63 B Raf 63 NS4B 63 telomerase activation 63 poly ADP ribose polymerase 63 Epidermal Growth Factor Receptor 63 mitogenic 63 histone deacetylase inhibitors 63 STAT3 63 microtubule dynamics 63 PPARgamma 63 HER2 expression 63 PTPN# 63 Akt1 63 EGFR HER 63 suppressor cells 63 Protease inhibitors 63 receptor tyrosine kinase inhibitor 63 Panzem 63 TRAIL induced apoptosis 63 LHRH antagonists 63 chromosomal rearrangement 63 tumor hypoxia 63 somatostatin receptors 63 molecular pathways 63 humanised monoclonal antibody 63 PHD2 63 keratinocyte 63 glutamate receptors 63 Virulizin ® 63 GPR# [002] 63 TNF tumor necrosis 63 immunotoxin 63 protein tyrosine kinase 63 CB2 receptor 63 intracellular signal transduction 63 eIF4E 63 PI3K signaling pathway 63 calcineurin 63 anticancer activity 63 Aurora kinase 63 GMX# 63 Dr. Bezprozvanny 63 Skp2 63 tubulin inhibitor 63 topoisomerase II 63 Bcr Abl mutations 63 deacetylase inhibitors 63 MAPKs 63 lipid synthesis 63 Th# 63 enzyme inhibitor 63 investigational antibody 63 Tß4 63 PAK1 63 VIPR2 63 receptor molecule 63 flavopiridol 63 PDGF B 63 CCR9 63 AhR 63 antiapoptotic 63 alkylating agent 63 tyrosine kinases 63 PLX MS 63 NFκB 63 CDK4 63 leukocyte adhesion 63 Beta catenin pathway 63 USP# 63 AEG# 63 signal transduction inhibitors 63 prognostic markers 63 Aromatase 63 BRAF gene 63 immune modulator 63 HDACi 63 GPNMB 63 immunostimulatory 63 melanocortin receptors 63 factor TNF 63 monocytes macrophages 63 EGFR HER2 63 BRAF inhibitor 63 neuropilin 63 bioactive lipids 63 serine threonine 63 HIV protease 63 TMEM#B 63 diagnostic biomarker 63 PKM2 63 gene rearrangements 63 mediated inhibition 63 proapoptotic 63 EGFR signaling 63 impair fertility 63 miR #a [002] 63 anti apoptotic proteins 63 inflammatory cascade 63 intracellular proteins 63 cytotoxins 63 transgene expression 63 Factor Receptor 63 lymphangiogenesis 63 JAK#/JAK# 63 CYP#A# CYP#D# 63 Gleevec inhibits 63 TXNIP 63 JAK STAT pathway 63 antiangiogenic therapy 63 mTOR inhibition 63 #beta HSD1 63 JAK inhibitors 63 tumor suppressive 63 humanised antibody designed 63 prostaglandin synthesis 63 interferon pathway 63 SIRT2 63 HMGCR 63 Angiolix 63 antifibrotic 63 genomic alterations 63 NKX#.# 63 biomarker identification 63 GNAQ 63 GPIIb IIIa 63 ErbB3 HER3 63 selective modulator 63 engineered RAP peptides 63 inverse agonist 63 FBPase 63 aberrant activation 63 oral JAK1 63 Integrins 63 inhibit vascular endothelial 63 PI3K/Akt pathway 63 leukocyte recruitment 63 dihydrofolate reductase 63 mesothelin 63 PlGF 63 CXCR7 63 BCL#A 63 IGF1R 63 VEGFR 63 invading pathogen 63 demethylating agents 63 DFMO 63 mutant BRAF 63 xenograft models 63 synapse formation 63 antiangiogenic agent 63 BRAF kinase 63 CYC# 63 RANKL 63 TGF ß 63 epithelial cell 63 induce apoptosis 63 HuLuc# 63 SERCA2a 63 androgen receptor 63 MAPK signaling pathway 63 proteoglycan 63 melanocyte 63 JAK STAT signaling 63 heparanase 63 osteogenic 63 anti inflammatory cytokine 63 HER1 63 Fas ligand 63 CBLC# 63 Clusterin 63 EGFR signaling pathway 63 treating neuropathic pain 63 ixabepilone 63 M1 macrophages 63 metalloprotease 63 STK# [002] 63 HCV replicon 63 CD#L 63 Mcl 1 63 C EBP alpha 63 TCF#L# 63 malignant transformation 63 Notch signaling 63 Mdm2 63 myogenesis 63 VEGF receptors 63 Pseudomonas aeruginosa infections 63 Aurora kinases 62 neurotrophins 62 endogenous ligands 62 HER2 protein 62 metabolic enzymes 62 cyclin dependent kinases CDKs 62 chemokine receptors 62 hepatic fibrosis 62 fast skeletal troponin 62 LKB1 62 mTOR 62 GATA3 62 SIRT3 62 aromatase enzyme 62 myeloid derived 62 thalidomide Thalomid 62 EGFR 62 MDSCs 62 neuroinflammation 62 retinoic acid receptor 62 SATB1 62 autoreactive T cells 62 trans splicing 62 Oncogenic 62 proliferative disorders 62 selectively inhibit 62 NF KB 62 selectively inhibiting 62 lung metastasis 62 demethylation 62 Hedgehog signaling pathway 62 Hedgehog inhibitor 62 NF KappaB 62 miR #b [002] 62 angiogenesis inhibition 62 tumor metastases 62 potent inducer 62 5 HT2A serotonin 62 osteoblast 62 p# alpha [002] 62 BRAF mutation 62 elastase 62 tumorigenicity 62 hepatocyte growth 62 CCX# 62 Th2 cells 62 Src 62 HDAC inhibition 62 serine protease 62 inhibit metastasis 62 AKT pathway 62 MEK inhibitors 62 obatoclax 62 glucokinase 62 druggable targets 62 multidrug resistance 62 morphogens 62 ADVEXIN therapy 62 N Myc 62 immune suppressive 62 hypoxia inducible factor 62 signaling pathways 62 NS4A 62 OGG1 62 SPINK1 62 downregulation 62 microRNA molecules 62 Nod1 62 P#X# receptors 62 RAS MAPK pathway 62 trastuzumab Herceptin ® 62 E1A 62 ALK inhibitor 62 APOPTONE 62 downregulating 62 CXCR4 62 pancreatic islet 62 malaria parasite Plasmodium falciparum 62 Siglec 8 62 endosomal release 62 RNAi mediated 62 NKT cell 62 mutational status 62 XL# inhibits 62 eTag assays 62 CDDO Im 62 OXi# 62 PIP3 62 UsiRNAs 62 PROCHYMAL 62 antisense inhibitors 62 anti angiogenic agents 62 autophagic 62 MAbs targeting 62 CENP E 62 TLR8 62 B lymphocyte stimulator 62 inhibits protein synthesis 62 Fc receptor 62 defective CFTR protein 62 small molecule tyrosine 62 antiangiogenic agents 62 Notch receptor 62 CCR2 receptor 62 beta adrenergic receptors 62 P#X# receptor 62 secretory phospholipase A2 62 TGF alpha 62 sortilin 62 EZH2 62 seliciclib 62 targeting CD# 62 protein kinase inhibitor 62 tumorigenic 62 bispecific 62 EphB2 62 DNA gyrase 62 inhibit VEGF 62 p#INK#a 62 neuronal differentiation 62 GGTase 62 mGluR4 62 vimentin 62 Sudhir Agrawal D.Phil 62 muscarinic 62 IL 1ß 62 costimulation 62 pre malignant lesions 62 ERBB2 62 HER2 positivity 62 integrins 62 casein kinase 62 #HT#A 62 MAP kinases 62 inhibiting telomerase 62 glucocorticoid receptor 62 sclerostin 62 Darapladib 62 synaptogenesis 62 sphingosine kinase 62 telomere dysfunction 62 adhesion molecule 62 PAR1 62 #ME# 62 tumor suppressors 62 antiplatelet medications 62 ABCG2 62 ischemic tissues 62 hCG Beta 62 chemotherapeutic agent 62 antisense RNA 62 adenosine receptor 62 XmAb# 62 MMP inhibitors 62 immune dysregulation 62 antitumoral 62 XBP1 62 ERK5 62 mitotic kinesin 62 deacetylation 62 Notch signaling pathway 62 ADPKD 62 Helicobacter pylori H. pylori 62 hyperactivation 62 receptors EGFR 62 cartilage degeneration 62 protein misfolding 62 hypoxic tumors 62 anti atherogenic 62 Tyrima 62 VEGF inhibitors 62 VKORC1 62 intracellular bacteria 62 microRNA expression 62 prostate cancer CaP 62 cyclin E 62 NF kB signaling 62 apoptosis induced 62 anti angiogenic therapy 62 mitochondrial decay 62 pro apoptotic 62 transcriptional activation 62 TGFß 62 resolvins 62 enzymatic pathways 62 IL6 62 antithrombotic 62 neurturin 62 systemic antifungal 62 PKCi 62 Chk1 62 breast cancer subtypes 62 photosensitiser 62 androgen receptors 62 platelet activation 62 pathophysiological effects 62 epigenetic alterations 62 bacterial virulence 62 anticancer therapeutics 62 imatinib Gleevec ® 62 estrogen receptors 62 NKT cells 62 PECAM 1 62 ADME properties 62 matrix metalloproteinases MMPs 62 CCR1 62 MetAP2 62 5 HT4 receptor 62 lymphoid organs 62 oncoproteins 62 CEA CD# Her2 62 M.tb 62 eotaxin 62 innate immune responses 62 stem cell pluripotency 62 tumor suppressor protein 62 fibrin deposition 62 pathogenic mechanisms 62 beta arrestin 62 mediated apoptosis 62 Eg5 62 splice variants 62 nitric oxide synthase 62 virotherapy 62 B7 H4 62 molecular determinants 62 5 HT4 62 antiproliferative 62 endocrine therapies 62 CEACAM1 62 Wnt signaling 62 KRAS mutation 62 Anticalins ® 62 bortezomib Velcade 62 Th# cells 62 basolateral 62 JAK2 62 leukaemic stem cells 62 transthyretin 62 tissue fibrosis 62 JAK kinases 62 endoxifen 62 humanized monoclonal antibodies 62 inhibiting mTOR 62 β catenin 62 reverse transcriptase 62 posttranslational modifications 62 Interferon beta 62 Notch receptors 62 cardiotoxic 62 bioactive lipid 62 SCD1 62 radiosensitivity 62 ubiquitination 62 inflammasome 62 NFAT 62 phosphatases 61 TKI therapy 61 Smad3 61 cell adhesion molecules 61 PPAR γ 61 Talabostat 61 serine threonine kinase 61 clusterin 61 effector cells 61 mesenchymal cell 61 metastatic neuroendocrine tumors 61 HGS ETR2 61 certain protein tyrosine 61 MTHFR 61 CMV infections 61 caveolin 1 61 Panzem NCD 61 NADPH oxidase 61 arginase 61 oncogenes 61 microglial cells 61 accumulate preferentially 61 receptor gamma 61 oral prodrug 61 Vpu 61 protein CETP 61 ZOLINZA 61 ribonucleotide reductase clinically validated 61 predictive biomarker 61 Apo2L 61 Ets2 61 BMP signaling 61 airway remodeling 61 molecular pathway 61 chromosomal mutations 61 prostaglandin E2 PGE2 61 BRAF protein 61 fibrocytes 61 PI3K inhibitors 61 delta isoform 61 cyclic adenosine monophosphate cAMP 61 cell adhesion molecule 61 focal adhesion kinase FAK 61 Factor VIIa 61 myelofibrosis polycythemia vera 61 MAPK 61 IL #p# 61 preferentially bind 61 Raf MEK ERK 61 IgG1 antibody 61 lymphocyte activation 61 ErbB2 61 serotonin reuptake 61 p# inhibitor 61 soluble receptor 61 FUS1 61 posttranslational modification 61 orally administered inhibitor 61 hormone deprivation 61 Fibroblast 61 NS#/#A protease 61 thromboembolic disease 61 inhibit replication 61 rapamycin mTOR 61 CaR 61 Nanobody 61 estrogen receptor beta 61 beta catenin protein 61 BMP4 61 immunomodulatory properties 61 Xanafide 61 basic fibroblast 61 erythropoietic 61 microglial 61 CaM kinase 61 gastrointestinal stromal tumors GIST 61 autocrine 61 cardiac fibrosis 61 factor IXa 61 p# protein 61 telomerase inhibitor 61 CDK inhibitor 61 chromatin structure 61 IFRD1 61 ErbB3 61 antibody fragment 61 mutated BRAF gene 61 Tarvacin 61 allosteric 61 JAK STAT 61 tryptase 61 FGFR3 61 antimetabolite 61 EGFR inhibition 61 mTORC1 61 pharmacodynamic biomarkers 61 lung fibrosis 61 p# mitogen activated 61 adeno associated viruses 61 NO synthase 61 vitamin D receptors 61 HER2 positive cancers 61 Mucosal 61 Akt signaling 61 IFN gamma 61 acetylcholinesterase AChE 61 chemically modified siRNA 61 evolutionarily conserved 61 myeloid 61 pan HDAC inhibitor 61 eNOS 61 related apoptosis inducing 61 signal transduction pathways 61 axonal degeneration 61 Epstein Barr Virus EBV 61 Nedd4 61 cediranib 61 optimized siRNA 61 ganetespib 61 fulvestrant 61 STAT4 61 Cyclin E 61 cytotoxic therapies 61 gene loci 61 hypermethylation 61 HER2 receptors 61 N cadherin 61 antiviral compounds 61 mutant KRAS 61 selectively induce apoptosis 61 histone deacetylation 61 Vidaza ® 61 Tarvacin Anti Viral 61 siRNA knockdown 61 chemotherapeutic drug 61 hepatic stellate cells 61 MDR1 61 HIF1 61 CXCL5 61 Factor Xa 61 Glioblastoma multiforme GBM 61 DACH platinum 61 angiogenic 61 small molecule activators 61 cardiomyocyte 61 gamma H2AX 61 SGLT2 inhibitors 61 biologic therapeutics 61 siRNA mediated 61 amyloid protein plaques 61 heme oxygenase 61 MET amplification 61 transcriptional repressor 61 apoptotic pathways 61 Macrophage 61 ANGPTL4 61 post transcriptional 61 HCV polymerase 61 proinflammatory cytokine 61 VEGFR1 61 Wnt proteins 61 PCNSL 61 targeted antifolate 61 pancreatic lung 61 novel VDA molecule 61 CYP#D# gene 61 gonadotrophin releasing hormone 61 potentiator 61 OMP #M# 61 Oxidative damage