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(Click for frequent words.) 68 endoplasmic reticulum 67 vesicle 67 lysosome 67 endosomes 67 Golgi apparatus 67 plasma membrane 66 endocytosis 65 dynein 65 cohesin 65 endocytic 64 cytoplasmic 64 vacuole 64 lysosomes 64 F actin 64 endosomal 64 vacuolar 64 Rab5 64 cytosol 64 membrane protein 64 Cdc# 64 endoplasmic reticulum ER 64 intracellular 63 organelles 63 coiled coil 63 cytoplasmic domain 63 clathrin 63 presynaptic 63 histone 63 organelle 62 basolateral 62 disulfide bond 62 mesoderm 62 transmembrane protein 62 nucleolar 62 centrosome 62 caveolae 62 ATPase 62 synaptic vesicles 62 tRNA 62 tubule 62 centrosomes 62 endosome 62 intercellular 62 epithelia 62 ubiquitin 62 mitotic spindle 62 cadherin 61 GLUT4 61 centromeres 61 microtubule 61 Rab# 61 cytosolic 61 actin cytoskeleton 61 plastid 61 phosphorylates 61 RecA 61 GTPase 61 β 61 proteolysis 61 ciliated 61 actin filaments 61 PrP 61 microtubules 61 recycling endosomes 61 cytokinesis 61 centromere 61 nucleosome 60 intramolecular 60 transmembrane 60 endonuclease 60 E cadherin 60 actin 60 GAPDH 60 AMPA receptors 60 transmembrane domain 60 cell cytoplasm 60 biogenesis 60 cilium 60 heterochromatin 60 vesicles 60 Vps# 60 heterochromatic 60 proteasomes 60 syntaxin 60 ectodomain 60 ubiquitylation 60 focal adhesions 60 auxin 60 transmembrane domains 60 polypeptides 60 kinase domain 60 fibronectin 60 extracellular 60 dimers 59 polypeptide 59 vesicular 59 glial 59 enterocytes 59 epithelial cells 59 autophagic 59 hnRNP 59 acetylation 59 fibril 59 cell motility 59 secretory pathway 59 paxillin 59 apical membrane 59 tubules 59 RNA strand 59 transcriptional repressor 59 subcellular localization 59 homodimer 59 tetramer 59 EF Tu 59 acetyl CoA 59 H2AX 59 JAK STAT 59 dendritic spines 59 oligomerization 59 helices 59 chloroplast 59 proline rich 59 dimer 59 cofactor 59 peroxisomes 59 cytoskeletal proteins 59 amino terminal 59 transcriptional activation 58 morphogen 58 transferrin receptor 58 cytoplasm 58 synthase 58 transporter proteins 58 neurites 58 Fig. 2C 58 ubiquitination 58 mRNA 58 Oncogenic 58 histone H3 58 FGFR3 58 tetramers 58 synaptic vesicle 58 dimeric 58 ligand induced 58 ESCRT 58 neural crest 58 hexamer 58 pRb 58 TRF1 58 isoforms 58 metaphase 58 microglial 58 heparan sulfate 58 adipocyte 58 transcriptional regulation 58 glycoproteins 58 cytoskeletal 58 gamma H2AX 58 E3 ligase 58 proteolytic cleavage 58 carboxyl terminal 58 amino acid residues 58 chromatin 58 PIP2 58 CFTR 58 COOH terminal 58 fission yeast 58 centromeric 58 receptor molecule 58 chromosomal DNA 58 trimeric 58 CXCL# 58 uPAR 58 mutant proteins 58 myosin II 58 paracellular 58 viral RNA 57 tau protein 57 SAP# 57 Macrophage 57 CaM 57 Wnts 57 Fig. 1C 57 postsynaptic 57 TGFß 57 chemoattractant 57 Fig. 1A 57 supramolecular 57 astrocytic 57 oligomeric 57 phagocytosis 57 epididymis 57 phagosome 57 MALAT1 57 cardiac myocytes 57 Wnt signaling 57 Cx# [001] 57 dynamin 57 ABCA1 57 RhoA 57 lipid droplets 57 homologs 57 lysates 57 fig. S3 57 HtrA2 57 telomeric 57 Arp2 3 57 fig. S1 57 MEF2 57 efflux 57 tubulin 57 catenin 57 epithelial 57 secretory 57 ribozyme 57 FtsZ 57 proteasome 57 p# NTR 57 γ 57 glycosylation 57 chloroplasts 57 Aβ 57 proto oncogene 57 perivascular 57 XBP 1 57 huntingtin 57 Microtubule 57 rRNA 57 apical 57 lamin 57 phagosomes 57 mRNAs 57 adhesion molecule 57 PML RARA 57 cyclin B1 57 phosphatidylinositol 57 anion 57 RNAs 57 guanine 57 lymphatic vessels 57 vimentin 57 mutant protein 57 entorhinal cortex 57 hippocampal neurons 57 mitochondrion 57 hyperactivation 57 acinar 57 eukaryotic cells 57 isoform 57 dentate gyrus 57 histone modifications 57 Phosphorylation 57 RNA polymerase II 57 actin filament 56 condensin 56 multivesicular bodies 56 integrins 56 centrioles 56 SUMOylation 56 exocytosis 56 mannose 56 CTCF 56 motoneurons 56 piRNAs 56 disulfide bridges 56 constitutively active 56 mitogen activated protein kinase 56 Ago2 56 gp# [002] 56 anaphase 56 synthetase 56 dendritic 56 morphogenesis 56 glutamate receptor 56 6S RNA 56 protein complexes 56 RAD# [001] 56 lysosomal 56 actin binding 56 kinetochores 56 epidermal cells 56 histone proteins 56 mitochondrial gene 56 striatal 56 E3 ubiquitin ligase 56 apoptotic cells 56 epithelial cell 56 cellular membranes 56 constitutively 56 disulfide bonds 56 P gp 56 keratinocytes 56 glycosyltransferase 56 proximal tubule 56 dynactin 56 RNA splicing 56 adherens junctions 56 neuronal cell 56 SVZ 56 arrestin 56 VE cadherin 56 Rac1 56 Ca2 + 56 vascular endothelial cells 56 phosphoprotein 56 metalloproteases 56 Fig. 1B 56 fibroblast cells 56 phosphorylation 56 Argonaute 56 intestinal epithelium 56 dendrite 56 erythrocytes 56 Saccharomyces cerevisiae 56 Rap1 56 conformational changes 56 MDCK cells 56 HOTAIR 56 cathepsin B 56 dimerization 56 importin 56 ribosomal protein 56 heterodimers 56 flavin 56 membrane proximal 56 TGF ß 56 cytoskeleton 56 cysteine 56 Fig. 2b 56 mesenchyme 56 phosphorylated 56 transduced 56 polypeptide chain 56 homodimers 56 catalytic subunit 56 midgut 56 TFIIH 56 nucleosomes 56 cadherins 56 melanocyte 56 caveolin 1 56 embryogenesis 56 cell adhesion molecules 56 Smad3 56 PcG 56 H#K#me# 56 chromatin structure 56 evolutionarily conserved 56 colocalization 56 translocates 56 transmembrane receptor 56 mammalian cells 56 TGF β 56 intron 56 sister chromatids 56 membrane vesicles 56 proteins 56 P. gingivalis 56 phosphorylate 56 cellular organelles 56 heterodimer 56 ERK1 2 55 tropomyosin 55 BMP signaling 55 lamellar 55 granule cells 55 receptor mediated endocytosis 55 cardiac fibroblasts 55 polyadenylation 55 ubiquitinated 55 helicase 55 histones 55 ribosomal 55 fluorescently labeled 55 ligand binding 55 intestinal epithelial cells 55 axon guidance 55 primary cilium 55 Polycomb 55 cultured neurons 55 myofibroblasts 55 perinuclear 55 polycystin 55 histidine 55 coexpression 55 Intracellular 55 chemotaxis 55 Fig. 3b 55 synapse formation 55 transferase 55 Htt 55 Fig. 3B 55 neuromuscular junction 55 regulates gene expression 55 cell nuclei 55 synaptic 55 constitutively expressed 55 encodes protein 55 dephosphorylation 55 lipid bilayer 55 miR# 55 adduct 55 TGFβ 55 FOXO 55 alpha synuclein 55 axon 55 outer membrane 55 progerin 55 operon 55 heme 55 BMAL1 55 Dynein 55 disulfide 55 keratinocyte 55 lipid rafts 55 mitosis 55 intergenic 55 carboxy terminal 55 Aβ# 55 iNOS 55 membrane proteins 55 intracellular compartments 55 methyltransferase 55 stilbene 55 estrogen receptor alpha 55 subunits 55 ubiquitin ligase 55 STIM1 55 cofilin 55 trans Golgi network 55 LRP6 55 ligand receptor 55 morphogens 55 serine protease 55 vacuoles 55 spectrin 55 mice lacking 55 Langerhans cells 55 Math1 55 eukaryotic 55 DNMT1 55 IKKß 55 histone H4 55 vesicle fusion 55 secretory cells 55 myosin VI 55 regulated kinase ERK 55 autophagy 55 vesicle membrane 55 oligomer 55 astrocytes 55 EGFP 55 AMPA receptor 55 isomerase 55 MDSCs 55 Notch signaling 55 fibrillar 55 occludin 55 RNA binding 55 Hedgehog signaling 55 fluorescently tagged 55 synaptogenesis 55 epithelial mesenchymal transition 55 PAX5 55 Sp1 55 BMP4 55 ssDNA 55 antiparallel 55 choroid plexus 54 RNA polymerases 54 peripheral tissues 54 orthologous 54 Fig. 1a 54 ligase 54 spermatogenesis 54 neuroblasts 54 transgenic mice expressing 54 bilayer 54 neuronal migration 54 PDZ domains 54 SH2 domain 54 SOCS3 54 tRNAs 54 stromal 54 outer membrane proteins 54 Prox1 54 CCL# 54 eNOS 54 Purkinje cell 54 kinetochore 54 uracil 54 zebrafish embryo 54 introns 54 Nedd4 54 Dpp 54 Skp2 54 eIF2 54 #BP# 54 PIP3 54 subventricular zone 54 hydroxylation 54 primary cilia 54 rostral 54 calcium ion 54 exonuclease 54 Kupffer cells 54 APOBEC3G 54 neural crest cells 54 beta subunit 54 chaperone proteins 54 receptor mediated 54 GluR1 54 DISC1 54 membrane lipids 54 riboswitch 54 cholesterol efflux 54 glycan 54 budding yeast 54 multiprotein 54 Dicer enzyme 54 protein fragment 54 LKB1 54 beta globin 54 immunodominant 54 mitotic 54 lymphocyte 54 noncoding RNAs 54 At#g# 54 annexin V 54 transcytosis 54 osteoblast 54 germ cells 54 macrophage 54 immunoreactivity 54 secretase 54 XPB 54 neuroepithelial cells 54 semaphorin 54 Fig. 3A 54 S. cerevisiae 54 Hox genes 54 prokaryote 54 microglia 54 superfamily 54 tyrosine phosphorylation 54 serine 54 lipoxygenase 54 CagA 54 ERK1 54 virulence genes 54 peptidoglycan 54 hydrogenase 54 collagen fibers 54 MAPK 54 lipoproteins 54 homologous 54 intracellular signaling 54 Fig. 3a 54 huntingtin protein 54 ncRNAs 54 downregulated 54 cysteines 54 cytochrome c oxidase 54 ERK2 54 TAp# 54 paralogs 54 leukocyte 54 SLC#A# [002] 54 DSBs 54 mitochondrial proteins 54 PGCs 54 glycoprotein 54 SNAREs 54 spindle fibers 54 micelles 54 Sox# 54 stromal cells 54 c Src 54 NR2B subunit 54 MT1 MMP 54 viral genome 54 Vpu 54 TNFR 54 glycans 54 NEDD8 54 NFAT 54 messenger RNA 54 hexose 54 Notch1 54 cytochrome 54 mononuclear 54 H#K# [002] 54 epoxide 54 basal ganglia 54 epigenetic silencing 54 mammary cells 54 A. thaliana 54 tumor suppressor protein 54 histone protein 54 ligands 54 monocyte 54 serine threonine kinase 54 Histone 54 intracellularly 54 site directed mutagenesis 54 misfolded 54 protein tyrosine phosphatase 54 myelinated axons 53 membrane fusion 53 c myc 53 alternatively spliced 53 mutant SOD1 53 cypin 53 reticular 53 MMP9 53 kinase pathway 53 lymphoid 53 PAK1 53 microdomains 53 acetylcholine receptor 53 Figure 1C 53 metabolizing enzyme 53 FGF# 53 Ku# 53 transcriptional regulator 53 Fig. 1b 53 oxidative phosphorylation 53 cell adhesion molecule 53 molecule 53 retrotransposon 53 FOXO3a 53 translationally 53 X inactivation 53 hexamers 53 transcriptionally active 53 Fig. 1D 53 topoisomerases 53 chaperonin 53 Runx2 53 phytochrome 53 bacterial enzyme 53 anterior pituitary 53 leucine zipper 53 ovule 53 thymocytes 53 β catenin 53 polyamines 53 umbilical vein 53 ATP hydrolysis 53 intestinal epithelial 53 seminiferous tubules 53 Abeta 53 basolateral membrane 53 Fig. 2c 53 Vpr 53 costimulatory 53 dendritic cells DCs 53 noncoding 53 collagenous 53 hematopoietic cells 53 podocytes 53 MyoD 53 RANTES 53 SOD1 53 genes encoding 53 RNA polymerase 53 GRP# 53 focal adhesion 53 ribonuclease 53 trabeculae 53 RNA molecule 53 junctional 53 tetragonal 53 SWI SNF 53 synaptic cleft 53 STAT3 53 acyl CoA 53 Syt II 53 podocyte 53 Kv#.# 53 monocytes 53 p# p# 53 epithelium 53 capsid 53 tyrosine kinase 53 GABAergic interneurons 53 T lymphocyte 53 ciliary 53 catalytically active 53 aquaporin 53 amyloid precursor protein 53 neurons 53 amyloid fibrils 53 PU.1 53 neurite outgrowth 53 microvilli 53 signaling molecule 53 oligodendrocyte 53 TORC2 53 myocyte 53 proinsulin 53 transcription factor 53 Sonic hedgehog 53 interconversion 53 rhodopsin 53 actin polymerization 53 trimer 53 beta globin gene 53 neural progenitor cells 53 cytochrome c 53 extracellular signal 53 chromosome condensation 53 NKT cell 53 globular proteins 53 ephrin 53 alanine 53 Sonic Hedgehog 53 mutant huntingtin 53 MDR1 53 NR2B 53 deacetylation 53 cAMP signaling 53 interneurons 53 ERK signaling 53 cysteine residues 53 apoE4 53 proline 53 Cyclin D1 53 KLF4 53 RNA molecules 53 noncoding RNA 53 metalloproteinases 53 homologous recombination 53 glycosylated 53 cell membrane 53 calpain 53 p#NTR 53 nucleolus 53 HDAC6 53 Rad# 53 KaiC 53 cyclins 53 TGF ß1 53 messenger RNA mRNA 53 ectopic expression 53 Phylogenetic analysis 53 NHEJ 53 amyloid peptide 53 upregulation 53 XBP1 53 ganglioside 53 virion 53 NF kB signaling 53 transfected 53 Supplementary Fig 53 apoE 53 thyroid hormone receptor 53 protein tyrosine kinase 53 mitochondrial membrane 53 alveolar epithelial cells 53 pseudogenes 53 Cdk5 53 kinesin 53 hindbrain 53 cell adhesion 53 cyclin 53 Wnt proteins 53 HSCs 53 plasminogen 53 mesenchymal transition 53 cyclic AMP 53 mediated phosphorylation 53 RNA genome 53 Smoothened 53 fig. S4 53 mRNA expression 53 CPEB 53 orthologs 53 transmembrane proteins 53 fibrils 53 TIMP 53 neurone 53 receptor CD# 53 cortical neurons 53 LSD1 53 inducible 53 receptor protein 53 signaling cascade 53 isoprenoid 53 demethylase 53 radial glia 52 TSLP 52 Phenylalanine 52 scavenger receptor 52 Diels Alder reaction 52 macrocycle 52 Src 52 hemoglobin molecule 52 protein synthesis 52 endothelial cell 52 pyruvate kinase 52 somites 52 endogenous 52 suppressor gene 52 substituents 52 GlcNAc 52 palladin 52 upregulated 52 cerebellar 52 HIP1 52 myoblasts 52 paracrine 52 contractile ring 52 mesenchymal cells 52 downstream effector 52 β1 52 Wnt pathway 52 breast epithelial cells 52 Neuronal 52 efferent 52 p# mutations 52 chemotactic 52 Sertoli cells 52 immunoreactive 52 telomere maintenance 52 PrPC 52 Purkinje cells 52 adenine 52 estrogen receptor 52 conformational 52 enolase 52 lymphoid tissue 52 EZH2 52 protease 52 cathepsins 52 cyclin D1 52 Mre# 52 neural cells 52 FAK 52 murine 52 osteocalcin 52 overexpression 52 TGF beta1 52 Actin filaments 52 myocytes 52 endometrial cells 52 polyamine 52 MAPK pathway 52 sialic acid 52 lymphocytes 52 transduction 52 alpha helix 52 chromophore 52 amyloid peptides 52 chromatin remodeling 52 misfolded protein 52 telomeric DNA 52 bcl 2 52 CD1d 52 CIB1 52 nuclei 52 caudal 52 HOX genes 52 STAT1 52 dermal papilla 52 epithelial cells lining 52 palytoxin 52 intracellular proteins 52 immunoprecipitation 52 plexin D1 52 myosin 52 transactivation 52 Fig. 1E 52 synaptotagmin 52 thymic 52 porphyrin 52 naturally occurring enzyme 52 presenilin 52 Ubx 52 microglial activation 52 Hh 52 untranslated regions 52 TrkB 52 fibroblast 52 cytidine 52 messenger molecule 52 major histocompatibility complex 52 overexpressing 52 acinar cells 52 lipid membranes 52 lateral ventricle 52 meiotic recombination 52 cellular senescence 52 MMPs 52 dioxygenase 52 mouse embryo 52 neurite 52 methylation 52 prion proteins 52 p# protein 52 fibrocytes 52 activin 52 aminopeptidase 52 glial cell 52 Dysregulation 52 sphingomyelin 52 muscarinic receptors 52 phosphatase 52 SNARE complex 52 inner mitochondrial membrane 52 proteolytic 52 thioredoxin 52 collagen fibrils 52 Kinesin 52 Fig. 2a 52 molecular motors 52 Aß 52 Tie2 52 germline 52 proton pump 52 IL 1beta 52 bile acids 52 diffusible 52 oncoprotein 52 glutamate receptors 52 phospholipase 52 forebrain 52 photosystem II 52 MEK1 52 NMDAR 52 phospho 52 carboxyl 52 TGF b 52 GSK 3ß 52 quinone 52 Ser# 52 actin remodeling 52 P selectin 52 ceramide 52 skeletal muscle cells 52 stroma 52 neuroligins 52 Klf4 52 DLX5 52 redox reactions 52 PDZ domain 52 RNAP 52 Confocal microscopy 52 Th2 52 amyloid beta protein 52 interphase 52 DDB1 52 pDC 52 NMDA receptor 52 antigen receptor 52 Fig. 52 ribonucleic acid RNA 52 calmodulin 52 Hox gene 52 EGF receptors 52 amyloid β 52 activating mutations 52 macrophages 52 fluorescent molecules 52 SGK1 52 succinate dehydrogenase 52 mutant alleles 52 protein filaments 52 exons 52 lamina 52 depolarization 52 receptor gamma 52 mediated inhibition 52 substrate specificity 52 E1A 52 PTPN# 52 Monocyte 52 ligand binding domain 52 EBNA1 52 vasculature 52 LRP1 52 signaling pathway 52 nAChR 52 glycolysis 52 3' 52 null mice 52 focally 52 fibroblasts 52 Drosophila embryos 52 primordial germ cells 52 micelle 52 neuronal synapses 52 SIRT2 52 enteric nervous 52 mutated protein 51 ß catenin 51 imidazole 51 MEFs 51 CCL2