Related by context. All words. (Click for frequent words.) 73 Chronic inflammation 72 Oxidative damage 72 renal fibrosis 71 excitotoxic 71 Thyroid hormone 70 telomere maintenance 70 neuronal degeneration 69 fatty acid oxidation 69 podocyte 69 Insulin resistance 69 cardiac fibrosis 69 Smad3 68 mitochondrial mutations 68 carbohydrate metabolism 68 nitric oxide synthase 68 peroxynitrite 68 autophagic 68 Brain derived neurotrophic 68 reactive oxygen species ROS 68 excitotoxicity 68 amyloid peptide 67 telomere dysfunction 67 overactivation 67 allergic inflammation 67 oxidative stress inflammation 67 p# activation 67 myofibroblast 67 endoplasmic reticulum stress 67 airway remodeling 67 hyperactivation 67 Endothelial dysfunction 67 gluconeogenesis 67 intestinal epithelium 67 hypothalamic pituitary 67 proteoglycan 67 lipid peroxides 67 Adiponectin 67 fibrogenesis 67 atherogenesis 67 neuronal dysfunction 67 hypothalamic pituitary adrenal axis 67 synaptogenesis 67 endocrine glands 66 Genetic variation 66 catabolism 66 FGFs 66 Skeletal muscle 66 synaptic function 66 channelopathies 66 protein tau 66 antioxidant enzyme 66 TGF b 66 glucocerebroside primarily 66 Angiotensin II 66 superoxide dismutase 66 lipid peroxidation 66 brain derived neurotrophic 66 Prolactin 66 adrenal cortex 66 oxidative damage 66 pressure natriuresis 66 heme oxygenase 66 pancreas pancreatitis 66 prostaglandin synthesis 66 CHD7 66 excitatory neurotransmitter glutamate 66 ERK signaling 66 Hashimoto thyroiditis 66 transcriptional repressor 66 Vascular endothelial growth 66 ectopic expression 66 Aldosterone 66 JAK2 enzyme 66 cardiac hypertrophy 66 Diabetic neuropathy 66 Fas ligand 66 fatty acid synthase 66 PTH secretion 66 Uric acid 66 induced neuronal 65 microtubule dynamics 65 lymphatic vasculature 65 superoxide 65 retinoid X 65 Magnesium deficiency 65 brain neurotransmitter 65 regulates gene expression 65 mitogen activated protein kinase 65 lipofuscin 65 reactive oxygen 65 LRP5 65 Notch signaling 65 mutant huntingtin protein 65 nephron 65 glycation 65 hyperinsulinemia 65 oncogenic transformation 65 Hedgehog signaling 65 unstable detrusor muscle 65 LDL receptor 65 SIRT1 protein 65 TGFβ 65 tumor suppressor protein 65 KCNE2 65 chromosomal instability 65 oxidative stress 65 calcium homeostasis 65 cell adhesion molecules 65 beta amyloid peptide 65 eicosanoids 65 amyloid beta plaques 65 vascular inflammation 65 acetylcholine receptor 65 SGK1 65 lipoprotein metabolism 65 progressive neurodegenerative disorder 65 neuro endocrine 65 amyloid β 65 prostaglandin E2 65 Cathepsin B 65 hyperactivated 65 adipokine 65 hypothalamus pituitary 65 NF κB 65 spermidine 65 lymphocyte activation 65 Dysregulation 65 neurotransmitter glutamate 65 Pulmonary hypertension 65 heme oxygenase 1 65 vWF 65 secretase 65 TGF ß 65 Homocysteine 65 mitochondrial biogenesis 65 leaky gut 65 metabolic abnormalities 65 amyloid ß 65 exocrine 65 glomerular 65 eNOS 65 COX2 65 folate metabolism 65 reactive oxygen species 65 Oncogenic 64 proteolysis 64 impaired glucose metabolism 64 neurofibrillary tangles 64 natriuresis 64 PDE1 64 oncogenesis 64 inducible nitric oxide synthase 64 motor neuron degeneration 64 idiopathic pulmonary 64 inhibitory transmitter 64 Macrophage 64 adipocyte 64 NF kB signaling 64 peroxidation 64 phosphatidylinositol 3 64 toxic amyloid beta 64 mesenchymal transition 64 myopathies 64 Alu RNA 64 synovial cells 64 NF KappaB 64 androgen hormone 64 UCP2 64 extracellular signal 64 cellular metabolism 64 NFkappaB 64 PGC 1α 64 Akt signaling 64 systemic inflammation 64 Aß 64 axonal degeneration 64 Cyclin D1 64 proinflammatory cytokines 64 Amyloid beta 64 protein kinase C 64 insulin signaling pathways 64 ubiquinol 64 pathophysiological 64 soluble fms 64 genotoxic stress 64 ubiquitylation 64 genomic instability 64 diffusible 64 axonal damage 64 paraneoplastic 64 osteoclast activity 64 PDGFR 64 cardiac insufficiency 64 superoxide anion 64 adrenal hormones 64 apoE4 64 Inappropriate activation 64 neuromuscular junction 64 spermatogenesis 64 catecholamine 64 arterial inflammation 64 Male pattern baldness 64 dysregulation 64 naturally occurring amino acid 64 hypoxia inducible transcription 64 obesity insulin resistance 64 exocrine glands 64 disregulation 64 BRAF protein 64 osteoblast 64 Glucocorticoids 64 cardiolipin 64 osteogenic differentiation 64 CaM kinase II 64 endocannabinoid signaling 64 Wnt signaling 64 fibrotic disease 64 glucocorticoid hormones 64 Epstein Barr Virus EBV 64 serine protease 64 Ketoacidosis 64 myelin breakdown 64 signaling cascades 64 receptor gamma 64 neuroinflammation 64 Polycystic ovary syndrome PCOS 64 synaptic transmission 64 factor BDNF 64 humoral immunity 64 podocytes 64 STAT3 signaling 64 endothelial nitric oxide 64 Hypertrophic cardiomyopathy 64 upregulating 64 neuronal plasticity 63 cell adhesion molecule 63 Autophagy 63 thyrotropin 63 lysosomal 63 hepatic glucose production 63 c myc gene 63 Osteoclasts 63 Genetic predisposition 63 epigenetic alterations 63 SIRT6 63 phospholipase A2 63 activin 63 metalloproteinases 63 Diabetic nephropathy 63 collagen synthesis 63 caveolin 63 UCP1 63 melanocyte 63 neuronal differentiation 63 microglial 63 Acetylcholine 63 neuropeptide Y NPY 63 epigenetic inheritance 63 endothelial nitric oxide synthase 63 Glutamate 63 oxidases 63 leukocyte adhesion 63 cytokine signaling 63 hormone aldosterone 63 Aâ 63 p# MAPK 63 nitric oxide synthase NOS 63 collagen VI 63 estrogen metabolism 63 ERK1 2 63 androgen signaling 63 mitochondrial function 63 arachidonic acid AA 63 NADPH oxidase 63 oxidized LDL 63 PON1 63 underlying vasculopathy 63 γ secretase 63 lipid metabolism 63 acinar 63 neurotransmitter acetylcholine 63 GSNO 63 fibrin deposition 63 lymphangiogenesis 63 β amyloid 63 glucose homeostasis 63 TGF ß1 63 nitrotyrosine 63 fibrotic 63 Hypothalamic 63 Reactive oxygen species 63 acetylcholine neurotransmitter 63 adipogenesis 63 platelet activation 63 catenin 63 oxidative DNA 63 synapse formation 63 deacetylation 63 overactivated 63 inflammatory cascade 63 plasminogen activator inhibitor 63 melanocyte stimulating hormone 63 anti inflammatory cytokine 63 Genetic mutations 63 Aortic stenosis 63 signaling molecule 63 vascular endothelial 63 matrix metalloproteinases MMPs 63 glial derived neurotrophic 63 intestinal microflora 63 metabolizing enzyme 63 mitogen 63 myo inositol 63 IL6 63 Abeta# 63 neuronal function 63 histone deacetylases 63 PPAR γ 63 urinary excretion 63 polyunsaturated fatty acid 63 cellular senescence 63 GATA4 63 Zinc deficiency 63 Low density lipoprotein 63 reductase 63 potent inducer 63 neurotransmitter GABA 63 proapoptotic 63 gene p# 63 antibody mediated 63 fatty acid synthesis 63 sphingolipid 63 prostaglandin E2 PGE2 63 autoregulation 63 beta adrenergic receptors 63 hemoglobin molecule 63 adipokines 63 epigenetic silencing 63 TSLP 63 Hemorrhagic stroke 63 Factor VEGF 63 MAP kinase 63 CYP#B# 63 Myocardial infarction 63 Oxidative 63 aldehyde dehydrogenase 63 glucosides 63 neurite outgrowth 63 Fatty liver 63 metabolic disturbances 63 Endothelial 63 dysregulated 63 neurotransmission 63 metabolic abnormality 63 SCD1 63 iron homeostasis 63 glycogen metabolism 63 isoenzyme 63 NOD2 63 neuroligins 63 MEF2A 63 vascular permeability 63 HSF1 63 polyamines 63 MAP kinase pathway 63 cell motility 63 SMAD4 63 progranulin protein 63 mucus glands 62 lipogenesis 62 Hutchinson Gilford progeria 62 dopamine signaling 62 inflammasome 62 epithelial barrier 62 oligomeric 62 plasma lipids 62 catabolic 62 airway hyperresponsiveness 62 Misfolded proteins 62 phenotypic expression 62 cholesterol homeostasis 62 ADAMTS# 62 SETDB1 62 protein beta amyloid 62 Chronic pancreatitis 62 prothrombotic 62 insulin signaling pathway 62 transcriptional activation 62 MAP kinases 62 hormone secretion 62 Autoimmune disorders 62 aberrantly activated 62 intimal hyperplasia 62 redox reactions 62 proNGF 62 invadopodia formation 62 cystine 62 lung fibrosis 62 NR#A# 62 arachidonic acid 62 axon guidance 62 glutamatergic 62 MECP2 gene 62 Leukotrienes 62 anti apoptotic 62 Endothelin 62 dehydrogenases 62 PI3K signaling 62 Dystrophin 62 xanthine 62 muscarinic receptors 62 LDLR 62 pRb 62 demyelination 62 metabolic acidosis 62 amino acid homocysteine 62 chondrocyte 62 FGF2 62 NQO1 62 TXNIP 62 endoplasmic reticulum ER 62 PI3K pathway 62 desmosomes 62 LPS induced 62 proto oncogene 62 erythrocytes 62 naturally occurring enzyme 62 Aromatase 62 xenobiotic 62 Irritable bowel syndrome IBS 62 periodontal tissues 62 mitogenic 62 Bacterial vaginosis 62 arrhythmogenic 62 cholinergic neurons 62 leukemia inhibitory 62 proinflammatory cytokine 62 antiapoptotic 62 inherited retinal degeneration 62 Apolipoprotein E 62 Amyloid plaques 62 cholesterol metabolism 62 HPA axis 62 neuropeptide Y 62 mitochondrial oxidative 62 VE cadherin 62 ferulic acid 62 ß amyloid 62 Von Willebrand 62 Wernicke Korsakoff syndrome 62 proinflammatory 62 #ß HSD1 62 eotaxin 62 HGPS 62 Amino acid 62 lung epithelium 62 Atopic dermatitis 62 de novo mutations 62 myelination 62 regulated kinase ERK 62 mevalonate 62 Phosphorylation 62 chitinase 62 STAT4 62 upregulates 62 GPC5 62 autosomal dominant disorder 62 Skp2 62 Rap1 62 metabolic enzymes 62 neurotransmitters serotonin 62 intracellular signal transduction 62 BRAF gene 62 copper zinc superoxide 62 coenzyme 62 apoE 62 alpha synuclein protein 62 β cells 62 CaM kinase 62 neovascularization 62 Oxidative stress occurs 62 coronary artery atherosclerosis 62 tau protein 62 receptor subtype 62 amyloid beta peptides 62 #ß 62 proteoglycans 62 tumorigenesis 62 leptin signaling 62 mesenchymal cell 62 downstream effector 62 WNK1 62 aldosterone hormone 62 E#F# 62 malignant transformation 62 hyperparathyroidism 62 intracellular pathways 62 IL 1ß 62 apoptotic pathway 62 Stress hormones 62 downregulation 62 mitochondrial enzyme 62 chromatin remodeling 62 sphingomyelin 62 IRS1 62 Retinitis pigmentosa 62 fatty acid metabolism 62 p#NTR 62 adipogenic 62 beta amyloid peptides 62 PTPN# 62 androgen receptor AR 62 hydroxyl radical 62 epigenetic changes 62 nerve degeneration 62 elastic fibers 62 oxidative phosphorylation 62 NF kappaB activation 62 epigenetic modification 62 Src kinase 62 myogenesis 62 pro inflammatory cytokine 62 neuronal signaling 62 NKT cell 62 TNFalpha 62 Uveal melanoma 62 LKB1 62 Essential tremor 62 vasoconstrictor 62 paracrine 62 fat soluble vitamin 62 Helicobacter 62 thyroid dysfunction 62 amyloid cascade 62 Smad7 62 demethylation 62 factor HGF 62 Nitric oxide NO 62 ADPKD 62 Angiotensin converting enzyme 62 interferon pathway 62 neuronal synapses 62 mechanotransduction 62 myocardial fibrosis 62 Hsp# [001] 62 Rab5 62 pathophysiologic 62 serine threonine 62 cardiac myocytes 62 thromboxane A2 62 glia cells 62 elastase 61 potentially modifiable 61 estrone 61 Purkinje cell 61 misregulation 61 Endocannabinoids 61 myocyte 61 genus Plasmodium 61 microglial activation 61 glucocorticoid receptor 61 Eosinophils 61 tryptase 61 glutamate receptors 61 MC1R 61 palmitate 61 encodes protein 61 Thiamine 61 shortened telomeres 61 Monocyte 61 pathological hallmark 61 T lymphocyte 61 neurotransmitters dopamine 61 ß1 61 male hormone androgen 61 predisposing factor 61 lipid synthesis 61 proximal tubule 61 serine proteases 61 neuritic plaques 61 peroxisome 61 S nitrosylation 61 metabolic dysfunction 61 Abeta protein 61 cAMP signaling 61 MMP# 61 factor PlGF 61 histone methylation 61 beta defensin 61 amyloid deposition 61 TGF β 61 phosphorylated tau 61 hormone adiponectin 61 Malassezia 61 mimics estrogen 61 mTORC1 61 clot formation 61 autoinflammatory diseases 61 metallothionein 61 progranulin 61 intercellular communication 61 amyloid beta peptide 61 galanin 61 neuroinflammatory 61 MEK ERK 61 neuropsychiatric disorder 61 neurodegenerative disorder 61 FANCD2 61 cytoskeletal protein 61 mitochondrial respiration 61 improves insulin sensitivity 61 lung epithelial cells 61 antioxidant enzymes 61 neurotrophic 61 sterol regulatory 61 ALDH2 61 Vascular dementia 61 membrane fluidity 61 mineralocorticoid 61 arterial calcification 61 excitatory neurotransmitter 61 epithelial tissues 61 estrogen deficiency 61 Smad4 61 FGFR3 61 caspase activation 61 Frontal lobe 61 Enlarged prostate 61 Vasopressin 61 glucocerebroside 61 GABAA receptors 61 systemic amyloidosis 61 pancreatic endocrine 61 monogenic 61 advanced glycation end 61 glutamate neurotransmission 61 ovarian hormones 61 oligomerization 61 VLDL cholesterol 61 filaggrin 61 amyloid beta proteins 61 hormone secreted 61 gallstone formation 61 NFκB 61 tau proteins 61 SSc 61 dysgenesis 61 Vitamin D insufficiency 61 NAD + 61 osteolytic 61 Alpha lipoic acid 61 abnormal glucose metabolism 61 neuronal cell 61 adrenocortical 61 ectoderm 61 pathophysiological effects 61 ERBB4 61 epithelia 61 Pulmonary arterial hypertension 61 muscular dystrophies 61 SIRT1 gene 61 Peptide YY 61 cholecystokinin CCK 61 myofibroblasts 61 cofactor 61 metabolizing enzymes 61 Aβ 61 Cognitive impairment 61 goblet cells 61 TGF beta pathway 61 lipid homeostasis 61 abnormal angiogenesis 61 neural degeneration 61 lipoxygenase 61 elevated triglyceride levels 61 enzymic 61 PKC beta 61 Oestrogen 61 oxidative 61 growth hormone secretion 61 RIP1 61 Thyroid hormones 61 Dietary fats 61 COX enzymes 61 RUNX3 61 cyclic AMP 61 Genetic mutation 61 Upregulation 61 ACh 61 PHD2 61 plasminogen 61 TNF α 61 von Willebrand Factor vWF 61 Systemic lupus erythematosus 61 underlying pathophysiology 61 dopaminergic cells 61 hepatic insulin resistance 61 Vitamin B5 61 thyroid hormones 61 Diabetes mellitus 61 superoxide dismutase SOD 61 oxidant stress 61 chronic inflammation 61 Hypoxia Inducible Factor 61 Overexpression 61 glutamate signaling 61 Nod1 61 Connective tissue 61 hyperammonemia 61 cyclic guanosine monophosphate 61 mutated protein 61 efferent 61 metalloproteinase 61 mitochondrial dysfunction 61 adrenal hormone 61 LIS1 61 lipoprotein lipase 61 calcineurin 61 hyperprolactinemia 61 MECP2 61 ADAM# 61 neuritic 61 klotho 61 regulating gene expression 61 dioxygenase 61 Nicotinamide 61 endocrine dysfunction 61 gliosis 61 eicosanoid 61 apo B 61 pro angiogenic 61 phosphorylates 61 osteogenesis 61 Polyunsaturated fatty acids 61 GABA receptor 61 neurohormonal 61 Secondhand smoke exposure 61 DNA demethylation 61 gonadotropins 61 cyclic GMP 61 epigenetic regulation 61 AT1R 61 SIRT3 61 HER signaling pathway 61 amyloid proteins 61 hydroxylation 61 proteinases 61 collagen degradation 61 circadian clock genes 61 selective inhibition 61 IL 1β 61 inhibitory neurotransmitters 61 chromosomal aberrations 61 Hh pathway 61 synaptic plasticity 61 Subclinical 61 apoptosis induced 61 hyperphosphorylation 61 Sensorineural hearing loss 61 cyclic adenosine monophosphate cAMP 61 dephosphorylation 61 RANK ligand 61 TGF beta1 61 disease NAFLD 61 autocrine 61 actin polymerization 61 Mitochondrial 61 Cockayne syndrome 61 sortilin 61 secreted protein 61 prostaglandin D2 61 DNA hypomethylation 61 membrane lipids 61 hepatic steatosis 61 osteopontin 61 p# mutations 61 sFlt 1 61 genetic polymorphism 61 ankyrin B 60 EphB2 60 apoC III 60 cardiac fibroblasts 60 peroxisomal 60 PEDF 60 Amyloid Precursor Protein 60 transthyretin 60 vasodilatation 60 NKG2D 60 neurons degenerate 60 amino acid tyrosine 60 vascular calcification 60 syndrome FXTAS 60 multi factorial disease 60 AV conduction 60 estrogen receptor alpha 60 hepatic stellate cells 60 RANK Ligand 60 MEK1 60 plasma fibrinogen 60 CYP #A# 60 RAS RAF MEK 60 Atopic eczema 60 CagA 60 neuronal apoptosis 60 ferroportin 60 calcium excretion 60 GSTT1 60 Cyclin E 60 PDE5A 60 FMRP protein 60 Chondroitin sulfate 60 PrPC 60 metalloprotease 60 cytoskeletal 60 NKX2 60 GAPDH 60 inherited mutations 60 secretory pathway 60 polyamine 60 microvascular endothelial cells 60 ABCA1 60 sumoylation 60 Stress incontinence 60 vasoconstriction 60 Nrf2 60 TGF β1 60 PDGF CC 60 reactive oxygen molecules 60 alveolar macrophages 60 retinol binding protein 60 E3 ligase 60 Leydig cells 60 lymphatic vessel 60 neurotrophin 60 baroreflex 60 macrophage migration 60 disulfide bond 60 prefrontal cortical 60 tyrosine phosphorylation 60 proteolytic enzymes 60 thymidylate synthase 60 intracellular accumulation 60 coagulation cascade 60 leiomyoma 60 enzyme cofactor 60 ORMDL3 60 C5aR 60 Superoxide 60 keratinocyte 60 vasodilatory 60 hypercoagulability 60 uPA 60 TOP2A gene 60 angiotensinogen 60 neuron degeneration 60 microglial cells 60 Leydig cell 60 oligodendrocyte 60 Akt activation 60 bone resorption 60 Treg cell 60 Alzheimer disease pathogenesis 60 Clusterin 60 cholesterol efflux 60 cell signaling pathway 60 cyclic AMP cAMP 60 Abdominal fat 60 endogenous cannabinoids 60 TNF alpha cytokine 60 breast cancer metastasis 60 gamma aminobutyric acid GABA 60 underactive thyroid gland 60 frataxin 60 hormones secreted 60 IRAK1 60 neurexins 60 hepatic lipase 60 micronuclei 60 Ca2 + 60 osteocalcin protein 60 Oxygen deprivation 60 DHA fatty acid 60 osmotic stress 60 cathepsins 60 FGF# 60 Beta amyloid 60 tissue homeostasis 60 neuroendocrine 60 acetylation 60 aetiological 60 desmin 60 primary cilia 60 interstitial fibrosis 60 haematopoietic 60 antidiuretic hormone 60 GRNOPC1 contains 60 hedgehog signaling 60 anti inflammatory cytokines 60 β cell 60 brown adipose tissue 60 histone acetylation 60 Cryptococcus neoformans 60 Genistein 60 activated microglia 60 vasomotor 60 activate p# 60 Rho kinase 60 pyrimidines 60 posttranslational modification 60 intracellular signaling 60 amyloid beta plaque 60 Alpha synuclein 60 resorption 60 alkalosis 60 spongiform encephalopathies 60 Acute pancreatitis 60 neurofibromin 60 fatal myelination disorder 60 redox active 60 acetyl CoA 60 gene polymorphisms 60 catalase 60 HER2 positivity 60 Shortened telomeres 60 pathogenetic 60 Sarcopenia 60 β catenin 60 adipocyte differentiation 60 hematopoiesis 60 digesting enzymes 60 synuclein 60 nonvascular 60 bronchoalveolar 60 E cadherin expression 60 sex hormone estrogen 60 pro oxidant 60 intercellular signaling 60 neural crest 60 cyclooxygenase COX 60 osteoprotegerin 60 NOTCH1 60 cholinergic tone 60 retinal ganglion cell 60 Fatty acids 60 MMP9 60 mutans 60 Lumbar spinal stenosis 60 mediated inhibition 60 insulinlike growth 60 MMP2 60 cytokine receptor 60 Renin 60 reactive molecules 60 glucocorticoid receptors 60 neuroendocrine cells 60 c Src 60 anabolic hormone 60 anabolism 60 sulfation 60 AgRP 60 DNMT1 60 intracellular pH 60 transmembrane receptor 60 Runx2 60 NADPH 60 metabolic processes 60 renal tubular 60 protein misfolding 60 PPAR alpha 60 lichen planus 60 endothelial activation 60 tau phosphorylation 60 ARF1 60 da mage 60 Cancer cachexia 60 cytoprotective 60 glutamate receptor 60 IFNg 60 IL 1beta 60 huntingtin 60 c MET 60 hepatocyte growth 60 naturally occurring molecule 60 NFkB 60 NO synthase 60 phagocytosis 60 nNOS 60 lysophosphatidic acid 60 apoptotic cell 60 TGF Beta 60 dystroglycan 60 intestinal mucosa 60 hypoxia inducible factor 60 Genetic variants 60 serum parathyroid hormone 60 receptor tyrosine kinase 60 ketone bodies 60 debilitating neurodegenerative disorder 60 NFAT