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(Click for frequent words.) 77 etiology 72 pathogenic mechanisms 71 aetiological 71 pathophysiological mechanisms 69 endophenotypes 69 pathophysiological 69 etiologic 69 underlying pathophysiology 68 pathophysiologic 68 etiologic factors 68 pathogenetic 67 etiologies 67 pathophysiology 67 etiological 67 somatoform disorders 66 clinicopathological 66 pathogenesis 66 chronicity 66 Genetic predisposition 65 pathogenetic mechanisms 65 antiphospholipid syndrome 65 monoclonal gammopathy 65 paraneoplastic 65 atherothrombotic 65 alexithymia 64 sonographic appearance 64 genetic loci 64 gastric carcinoma 64 autonomic dysfunction 64 prognostic significance 64 underlying molecular mechanisms 64 pathophysiologic mechanisms 64 preoperative diagnosis 64 Kraepelin 64 neoplastic 63 susceptibility loci 63 syndromal 63 extramedullary 63 comorbid anxiety 63 myeloproliferative diseases 63 SSc 63 neuropsychiatric diseases 63 urolithiasis 63 predisposing factor 63 biopsychosocial 63 nosology 63 genetic polymorphisms 63 comorbid depression 63 Sjögren syndrome 63 neuropsychiatric disorders 63 familial clustering 63 neuropathologic 63 causal pathways 63 intracranial hypertension 63 neuroanatomical 63 airway hyperresponsiveness 63 ANCA associated 62 hypochondriasis 62 myeloproliferative disorders 62 clinicopathologic 62 CP CPPS 62 comorbid disorders 62 Prognostic factors 62 etiologic agent 62 essential thrombocythemia 62 prostate cancer CaP 62 MGUS 62 prognostic markers 62 differential diagnoses 62 syndromic 62 prognostic indicator 62 clinically heterogeneous 62 primary hyperparathyroidism 62 symptomatology 62 prognostic indicators 62 idiopathic pulmonary 62 recurrent miscarriage 62 myopathies 62 prostate carcinogenesis 62 DNA methylation patterns 62 Genetic susceptibility 62 atherogenesis 62 viral etiology 62 lichen planus 62 thyroid nodules 62 mucinous 62 Genetic variants 62 neuropsychological impairments 62 cryptogenic 62 epilepsies 62 pharmacologic intervention 62 idiopathic myelofibrosis 62 APOE genotype 62 radiographic findings 62 myocardial dysfunction 61 CTEPH 61 paragangliomas 61 motor neuron degeneration 61 phenotypic expression 61 thyroid dysfunction 61 Venous thromboembolism 61 potentially modifiable 61 pituitary adenomas 61 prodrome 61 thrombophilia 61 Zollinger Ellison Syndrome 61 gastric adenocarcinoma 61 urothelial carcinoma 61 unmeasured confounders 61 calculi 61 pathophysiologic mechanism 61 Leukemias 61 genetic determinants 61 sonographic diagnosis 61 diabetes mellitus DM 61 POAG 61 psychogenic 61 androgen deficiency 61 pain syndromes 61 hyperacute 61 pericardial effusion 61 delayed gastric emptying 61 pulmonary hypertension PH 61 Cognitive impairment 61 syndromes 61 thromboembolic disease 61 ALI ARDS 61 leiomyomas 61 myeloproliferative 61 genetic locus 61 mycosis fungoides 61 genetic polymorphism 61 physiologic mechanisms 61 nonalcoholic steatohepatitis NASH 61 euthymic patients 61 Cardiotoxicity 61 neoplasm 61 familial aggregation 61 stratifying patients 61 missense mutations 61 molecular biomarkers 61 kinase inhibition 61 pharmacologic treatments 61 haematological 61 rheumatic disorders 61 Keratitis 61 myelofibrosis polycythemia vera 61 molecular mechanisms underlying 61 arrhythmogenic 61 predisposing factors 61 chromosomal rearrangement 61 virally induced 61 biochemical abnormalities 61 coagulopathy 61 poststroke depression 60 psychobiological 60 mito 60 demyelinating 60 diagnostic biomarker 60 multifactorial 60 gene polymorphisms 60 underdiagnosis 60 Bacterial vaginosis 60 hamartomas 60 neovascularisation 60 somatization disorder 60 comorbid psychiatric disorders 60 neuropathological 60 autistic enterocolitis 60 SLC#A# [002] 60 cervicitis 60 seminomas 60 bullous 60 neurocognitive deficits 60 molecular abnormalities 60 metabolic abnormalities 60 pathophysiological processes 60 prognostic marker 60 carcinoids 60 leiomyoma 60 Sezary syndrome 60 G6PD deficiency 60 pharmacological approaches 60 gastroduodenal 60 diathesis 60 differential gene expression 60 IntroductionThe 60 affective disorders 60 multicentric 60 Pneumocystis carinii pneumonia 60 Lipodystrophy 60 polyarticular 60 overt hypothyroidism 60 valvular heart 60 H pylori 60 neurosyphilis 60 subclinical atherosclerosis 60 periprocedural MI 60 angiographically 60 etiological factors 60 Chlamydia pneumoniae 60 Patellofemoral 60 colorectal carcinogenesis 60 diabetic microvascular complications 60 Diabetes mellitus 60 neuropsychological impairment 60 Chronic pancreatitis 60 hereditary predisposition 60 neurocognitive impairment 60 sCJD 60 Pseudomonas aeruginosa infections 60 granulomatous 60 Endothelial dysfunction 60 Idiopathic 60 rhinosinusitis 60 myeloproliferative neoplasms 60 neuronal dysfunction 60 hypothalamic pituitary adrenal axis 60 Hashimoto thyroiditis 60 mycosis 60 Etiology 60 myoclonus 60 Chronic Prostatitis 60 cystic lesions 60 Magnesium deficiency 60 somatic symptoms 60 nonpharmacologic 60 spontaneous regression 60 ataxias 60 breast cancer subtypes 60 psychiatric comorbidity 60 prodromal 60 airway remodeling 60 incidentalomas 60 cAMP signaling 60 immunological mechanisms 60 posttraumatic 60 histologic findings 60 genetic aberrations 60 Polycythemia vera 60 atherothrombotic disease 59 affective psychoses 59 metabolic dysfunction 59 dyslipidaemia 59 nonalcoholic steatohepatitis 59 biologic pathways 59 neuroinflammation 59 osteochondroma 59 neurological abnormalities 59 oncogenesis 59 nodal metastases 59 primary aldosteronism 59 neuritic 59 epithelial tumors 59 morphologic 59 chromosome #p#.# 59 HeFH 59 obesity insulin resistance 59 fibrosing 59 parkinsonian 59 pheochromocytoma 59 CYP#C# gene 59 psychopharmacologic 59 behavioral disinhibition 59 haematuria 59 reflux esophagitis 59 bronchogenic carcinoma 59 familial predisposition 59 Brugada syndrome 59 mitochondrial toxicity 59 adenomatous 59 polymicrobial infections 59 glucose abnormalities 59 pulmonary metastases 59 multi factorial 59 sacral neuromodulation 59 generalized epilepsy 59 hyperalgesia 59 hypogonadotropic hypogonadism 59 untreated psychosis 59 renal scarring 59 intracortical 59 inflammatory demyelinating 59 myocardial fibrosis 59 acetabular dysplasia 59 endoscopic ultrasonography 59 hypovitaminosis D 59 histopathological 59 myocardial ischaemia 59 mediastinitis 59 tumor histology 59 intracerebral haemorrhage 59 malignant lymphomas 59 bronchopulmonary dysplasia BPD 59 microvascular disease 59 Social Phobia 59 causal pathway 59 neurological manifestations 59 atherosclerotic vascular disease 59 primary dysmenorrhoea 59 somatic complaints 59 lipid abnormalities 59 sonographic findings 59 Intussusception 59 Parkinson Disease PD 59 hematopoietic cancers 59 enterocolitis 59 autoimmune thyroid 59 lung fibrosis 59 ADPKD 59 artery stenosis 59 prognostic biomarkers 59 Dysplasia 59 Genetic variation 59 immune dysregulation 59 MTHFD1L gene 59 splenic 59 CagA 59 ocular inflammatory 59 medically unexplained 59 hypercalciuria 59 superior mesenteric artery 59 hepatic cirrhosis 59 glomerulonephritis 59 pharmacological therapies 59 polygenic 59 sequela 59 Neurodegenerative diseases 59 pharmacokinetic interactions 59 T1DM 59 schizophreniform disorder 59 Adrenal Fatigue 59 coinfection 59 molecular determinants 59 nongenetic 59 EEG abnormalities 59 schizophreniform 59 bacterial prostatitis 59 neurologic complications 59 Dysregulation 59 hyperhomocysteinemia 59 pilocytic astrocytomas 59 cardiogenic 59 C. trachomatis 59 Ischemic 59 genetic heterogeneity 59 pleiotropic effects 59 premorbid 59 chronic hepatitis cirrhosis 59 comorbid psychiatric 59 nasal polyposis 59 SLNB 59 electrophysiologic 59 antiphospholipid antibodies 59 PCOD 59 pre malignant lesions 59 choroidal neovascularization 59 aerodigestive tract 59 multisystem disease 59 nonbacterial prostatitis 59 gastro esophageal reflux 59 myalgic encephalomyelitis 59 LVNC 59 emotional dysregulation 59 variant angina 59 membranous nephropathy 59 penetrance 59 tumor necrosis 58 polycythemia vera PV 58 progressive neurodegenerative disorder 58 multi factorial disease 58 mitochondrial disorders 58 aneurysmal bone cyst 58 Thyroid disorders 58 xenobiotic 58 renal fibrosis 58 mechanistic explanation 58 chronic obstructive airway 58 Chronic Fatigue Syndrome CFS 58 hypothalamic pituitary 58 gonococcal 58 Chronic lymphocytic leukemia 58 compulsive hoarding syndrome 58 neurobiological mechanisms 58 constipation OIC 58 epigenetic regulation 58 lipoprotein metabolism 58 metastatic neuroendocrine tumors 58 immunomodulation 58 origin PNH 58 Irritable bowel syndrome 58 polycythemia vera essential thrombocythemia 58 hyperinsulinism 58 asthma rhinitis 58 underlying vasculopathy 58 S. maltophilia 58 hematuria 58 clinico pathological 58 Onychomycosis 58 Subgroup analyzes 58 quasispecies 58 susceptibility locus 58 Leydig cell 58 esophageal carcinoma 58 neoplasms 58 affective psychosis 58 arterial hypertension 58 pyelonephritis 58 silent myocardial ischemia 58 thyrotropin 58 Adjuvant therapy 58 Wernicke Korsakoff syndrome 58 monogenic 58 antiangiogenic therapy 58 papular 58 SIADH 58 FTLD 58 cardiac conduction 58 molecular underpinnings 58 haematopoietic 58 esophagogastric 58 GISTs 58 cardiac allograft vasculopathy 58 Non Alcoholic Fatty 58 Parkinsonian Syndromes 58 pathologic 58 malignant neoplasms 58 germline mutations 58 AKT1 58 levodopa induced 58 microdeletion 58 Nanobacteria 58 immunopathology 58 fibrotic disease 58 protein tyrosine phosphatase 58 de novo mutations 58 gastric cardia 58 cutaneous lupus 58 macroalbuminuria 58 tumorigenicity 58 lymph node enlargement 58 intestinal permeability 58 invasive candidiasis 58 bone scintigraphy 58 torsade de pointes 58 scintigraphic 58 Raynaud syndrome 58 Autistic Disorder 58 pharmacotherapeutic 58 endocannabinoid signaling 58 adjuvant therapies 58 aortic regurgitation 58 diabetes dyslipidemia 58 connective tissue diseases 58 Epstein Barr Virus EBV 58 ccRCC 58 etiological agent 58 neurologic symptoms 58 schizotypal traits 58 BPS IC 58 Comorbid 58 Clinical Relevance 58 PAOD 58 childhood acute lymphoblastic 58 leaky gut 58 Oxidative damage 58 variceal bleeding 58 rheumatic disease 58 chronic thromboembolic pulmonary 58 supratentorial 58 amyloid cascade 58 chorioamnionitis 58 hydrops 58 nonvascular 58 metaplasia 58 infective endocarditis 58 hyperglycaemia 58 vasculopathy 58 fulminant 58 Barrett esophagus BE 58 complement inhibitor eculizumab 58 subclinical 58 hepatic fibrosis 58 hepatic lesions 58 metabolic abnormality 58 convergent validity 58 cholestasis 58 carcinoid tumor 58 choroidal vasculopathy 58 haematologic 58 osteoid osteoma 58 JAK mutations 58 circadian genes 58 chlamydial 58 choriocarcinoma 58 Rhinitis 58 C. pneumoniae 58 prostatitis 58 metabolomic profiles 58 EBV infection 58 ASCUS 58 Vgontzas 58 Periodontitis 58 epithelial barrier 58 CNTNAP2 58 vertebral subluxation 58 lupus scleroderma 58 tissue perfusion 58 pharmacodynamic biomarkers 58 GBA mutations 58 malperfusion 58 Systemic lupus erythematosus SLE 58 cortical dysplasia 58 presymptomatic 58 multisystemic 58 K ras mutations 58 lymphocytic 58 temporal arteritis 58 thromboembolic 58 ATG#L# 58 plexiform 58 telomere dysfunction 58 IPAH 58 hyperinsulinemia 58 murine models 58 TCF#L# gene 58 functional gastrointestinal disorders 58 HRQL 58 murine model 58 acid suppressive therapy 58 postoperative AF 58 postoperative delirium 58 pigmentary 58 hamartoma 58 fulminant hepatic failure 58 metastatic bone 58 thrombotic complications 58 vascular cognitive impairment 58 HSV1 58 inherited predisposition 58 neurogenic 58 histologic subtypes 58 macrovascular events 58 neuropsychiatric disorder 58 genomic alterations 58 herpetic 58 neurasthenia 58 DVT PE 58 serologic tests 58 vaso occlusive crisis 58 postoperative radiotherapy 57 liver metastasis 57 non pharmacological interventions 57 pseudotumor 57 BERKELEY CA UroToday.com 57 vascularisation 57 neuroregenerative 57 laterality 57 primary spontaneous pneumothorax 57 glaucomatous 57 thyrotoxicosis 57 psychiatric comorbidities 57 interstitial pneumonia 57 causative pathogen 57 COX2 57 residual confounding 57 HIV HCV coinfected 57 prognostically 57 bacteraemia 57 noncardiac 57 mitochondrial dysfunction 57 PCNSL 57 Sydenham chorea 57 bile acid metabolism 57 T1a 57 staphylococcal infections 57 multifactorial disease 57 aortic insufficiency 57 esophageal squamous cell carcinoma 57 demyelinating diseases 57 testicular tumors 57 MYH9 57 dopamine receptor gene 57 fibromyalgia syndrome 57 rheumatic diseases 57 imatinib resistance 57 Glucocorticoids 57 thromboembolism 57 HBV genotypes 57 sub syndromal 57 P. falciparum malaria 57 VCFS 57 myofascial pain syndrome 57 hypoxemia 57 Prostatitis 57 erythema nodosum 57 Chronic inflammation 57 microvascular dysfunction 57 ATTR CM 57 Neoplasms 57 juvenile idiopathic arthritis 57 Candida infection 57 GH deficiency 57 carcinomatosis 57 susceptibility genes 57 stress cardiomyopathy 57 subclinical hypothyroidism 57 chlamydial infection 57 carcinoid 57 coronary artery atherosclerosis 57 rheumatologic 57 asplenia 57 gastro oesophageal reflux disease 57 FGFs 57 biochemical markers 57 infantile colic 57 skeletal metastases 57 sporadic ALS 57 transient elastography 57 perineural 57 ALK mutations 57 optic atrophy 57 cardiac insufficiency 57 histologic subtype 57 Cyclin E 57 intersexuality 57 PsA 57 cardiac biomarkers 57 Angiotensin converting enzyme 57 cytopenias 57 microsatellite instability 57 transcriptional regulation 57 PON1 gene 57 mGluR5 inhibition 57 atopic 57 atrophic gastritis 57 Radiographic findings 57 EGFR mutation status 57 psychopathology 57 Aortic stenosis 57 proliferative diabetic retinopathy 57 psychopathological symptoms 57 Cutaneous 57 comorbidity 57 diabetic kidney 57 FDG PET imaging 57 efferent 57 antithrombotic agents 57 antibody mediated 57 cranial irradiation 57 heparin induced thrombocytopenia 57 Liver transplantation 57 orchitis 57 arteritis 57 sociodemographic variables 57 susceptibility gene 57 symptomology 57 hyperparathyroidism 57 methodologic 57 Haptoglobin 57 mechanistic studies 57 hyperplastic 57 explanatory variables 57 causative agents 57 Aggrastat ® tirofiban hydrochloride 57 cerebrovascular accidents 57 Raynaud disease 57 thyroid carcinoma 57 Brodmann Area 57 Subclinical 57 biologic plausibility 57 diagnose coronary artery 57 cerebral vasospasm 57 tryptase 57 nodal metastasis 57 unknown etiology 57 #q# deletion syndrome 57 autistic regression 57 fibrocystic 57 neurobiological underpinnings 57 hepatorenal syndrome 57 hypoperfusion 57 polymorphic ventricular tachycardia 57 vascular dysfunction 57 riociguat 57 anterior uveitis 57 pulmonary metastasis 57 necrotizing 57 CSF biomarkers 57 XMRV infection 57 Irritable Bowel 57 SRBD 57 breast endometrial 57 Neovascular AMD 57 dysthymic disorder 57 adenomyosis 57 antiangiogenic agents 57 hyperoxaluria 57 histological subtype 57 tonsillar 57 genetic syndromes 57 serum biomarkers 57 ependymomas 57 enthesitis 57 pathognomonic 57 mediated inhibition 57 renal cysts 57 probiotic supplementation 57 prodromal phase 57 CFS ME 57 molecular pathogenesis 57 mRNA decay 57 clefting 57 #F FDG PET 57 HER2 overexpression 57 humoral immunity 57 serous ovarian cancer 57 univariate analyzes 57 Helicobacter pylori infection 57 histologic diagnosis 57 N glycan 57 pharmacological interventions 57 pharmacological intervention 57 hypocalcaemia 57 epigenetic modification 57 pseudogout 57 neurobiological basis 57 molecular subtypes 57 Uncontrolled hypertension 57 aberrant activation 57 Frontal lobe 57 FDG uptake 57 Akathisia 57 Alternative splicing 57 myeloproliferative neoplasms MPNs 57 tonsillar hypertrophy 57 antitumor effect 57 psychiatric morbidity 57 epididymitis 57 prognostic factor 57 plasma lipid 57 Candidiasis 57 congenital anomalies 57 primary biliary cirrhosis 57 Vitamin D insufficiency 57 Lymph node 57 atrial tachyarrhythmias 57 dietary interventions 57 macrovascular complications 57 microangiopathy 57 Diabetic neuropathy 57 B streptococcal 57 HBeAg negative 57 HLA DRB1 57 polymyalgia rheumatica 57 kidney urologic 57 PTPN# 57 subsyndromal 57 thromboprophylaxis 57 bullous pemphigoid 57 genetic susceptibilities 57 herpes zoster shingles 57 TTR amyloidosis 57 proteoglycan 57 osteochondromas 57 N. gonorrhoeae 57 Atopic 57 inherited mutations 57 Prenatal diagnosis 57 neoplastic diseases 57 lymphoproliferative disorders 57 endotoxemia 57 adnexal mass 57 systolic hypertension 57 simplex virus 57 PNH patients 57 dysrhythmias 57 Acute respiratory distress 57 psychosocial stressors 57 IDH mutations 57 differential diagnosis 57 OSAHS 57 Prefrontal 57 TGF beta signaling 57 methicillin susceptible Staphylococcus aureus 57 AUDs 56 lymphocyte activation 56 extrapulmonary 56 gastro oesophageal reflux 56 AA Amyloidosis 56 Acute Renal Failure 56 valvular 56 dimensional sonography 56 Metastases 56 cervical lymph nodes 56 neuro endocrine 56 Phenotypic 56 occlusive disease 56 colonoscopic 56 systemic amyloidosis 56 neurotrophic 56 cerebral ischemia 56 meta analytic review 56 neuro developmental disorders 56 haemorrhagic 56 locoregional 56 anterior temporal 56 thiopurine 56 hypometabolism 56 atypical hemolytic uremic syndrome 56 neurogenic bladder 56 petechial rash 56 amyloid deposition 56 lupus multiple sclerosis 56 Basal Cell 56 astrocytic 56 biliary obstruction 56 neurosensory 56 nephrogenic 56 Chlamydia trachomatis 56 thrombo embolic 56 STK# gene 56 Zollinger Ellison syndrome 56 monozygotic twins 56 HRQOL 56 zoster 56 Hutchinson Gilford progeria 56 parenchymal 56 maturational 56 intracellular signal transduction 56 toenail onychomycosis 56 virulence genes 56 Idiopathic pulmonary fibrosis 56 Squamous 56 Sclerosing 56 adenomatous polyps 56 somatoform disorder 56 atopic diseases 56 psychopharmacological 56 Atopic eczema 56 allergic dermatitis 56 elevated CRP 56 decompensated cirrhosis 56 hallux limitus 56 gastrointestinal dysfunction 56 epistasis 56 EoE 56 hepatotoxicity 56 causative agent 56 Glycosylation 56 bladder carcinoma 56 astrocytomas 56 melanocytic 56 anatomic abnormalities 56 tuberculous 56 DSM IV Axis 56 benign positional vertigo 56 incompletely understood 56 nanobacteria 56 cognitive affective 56 unmeasured factors 56 progressive dyspnea 56 neuropathies 56 LV dysfunction 56 LPS induced 56 cataract glaucoma 56 Ischemic heart 56 causative genes 56 Hypothalamic 56 paraganglioma 56 Poisson regression 56 nociceptive pain 56 lupus anticoagulant 56 Socioeconomic status 56 anatomical abnormalities 56 genotype phenotype 56 Accurately identifying 56 microbiota 56 extrapyramidal 56 carotid plaques 56 thrombocytosis 56 adjunctive therapies 56 mosaicism 56 paresis 56 generalized tonic clonic seizures 56 CYT# potent vascular disrupting 56 Sexsomnia 56 tumor subtypes 56 Schizoaffective Disorder 56 nonhereditary 56 Kaplan Meier curve 56 Compulsive hoarding 56 Subtypes 56 node metastases 56 neurocognitive dysfunction 56 vasogenic edema 56 renal tumors 56 acute rheumatic fever 56 Chronic constipation 56 hormonal abnormalities 56 hyperuricaemia 56 streptococcal 56 Electroencephalography 56 γ secretase 56 Dental caries 56 #q#.# [002] 56 hydatid disease 56 constipation predominant irritable bowel 56 surrogate markers 56 testicular germ cell 56 Hypertrophic 56 vascular endothelial dysfunction 56 lymph node metastasis 56 neurologic diseases 56 intracranial hemorrhage ICH 56 proximal colon 56 posttranslational modifications 56 Wound healing 56 diagnostic modality 56 dysglycemia 56 intact parathyroid hormone 56 arterial calcification 56 tricuspid regurgitation 56 mania hypomania 56 Urinary tract 56 dissociative disorders 56 chronic periodontitis 56 aneuploidies 56 Lyme arthritis 56 chronic cerebro spinal 56 iritis 56 osteoporotic vertebral fractures 56 abnormal vaginal bleeding 56 oral thrush 56 oesophageal adenocarcinoma 56 hereditary hemochromatosis 56 hemolytic 56 causative mutations 56 hyperbilirubinemia 56 locoregional recurrence 56 confounder 56 sequelae 56 psychosocial functioning 56 radiculopathy 56 venous malformations 56 lysosomal storage diseases 56 Henoch purpura 56 genes differentially expressed 56 lung epithelium 56 sporadic Creutzfeldt Jakob 56 coinfected patients 56 ORMDL3 56 fluoroquinolone resistance 56 spondyloarthritis 56 β1 56 Diabetic nephropathy 56 Pathologic 56 ERK signaling 56 lymphangiogenesis 56 inhaled corticosteroid therapy 56 KRAS variant 56 carcinoid tumors 56 suppurative 56 myocardial infarction congestive heart 56 Ischaemic heart 56 repolarization 56 Nonalcoholic fatty liver 56 causative 56 allelic variation 56 logistic regression model 56 nephron sparing surgery 56 nasopharyngeal carcinoma 56 nonischemic 56 Fas ligand 56 leukoencephalopathy 56 dementia praecox 56 atopic disorders 56 Trichophyton rubrum 56 PLMs 56 hepatocellular 56 autoimmune thyroiditis 56 molecularly targeted therapies 56 KRAS oncogene 56 tumoral 56 dissociative symptoms 56 p# activation 56 chromosomal translocations 56 Sleep disordered breathing 56 hemorrhagic cystitis 56 fibroma 56 thrombocytopenic 56 ADAMTS# 56 T2DM 56 intravesical therapy 56 chromosomal anomalies 56 isotypes 56 heritable diseases 56 retrovirus XMRV 56 schwannoma