Related by context. All words. (Click for frequent words.) 80 amyloid plaque 78 beta amyloid 77 amyloid 77 beta amyloid plaques 74 neurofibrillary tangles 73 beta amyloid protein 73 tau protein 72 amyloid beta 72 amyloid beta protein 71 amyloid beta plaques 71 amyloid protein 71 amyloid deposits 70 Aβ 70 senile plaques 69 tau tangles 69 protein tau 68 tau proteins 67 protein beta amyloid 67 beta amyloid peptide 67 amyloid proteins 67 beta amyloid plaque 67 amyloid beta peptide 66 amyloids 66 amyloid beta peptides 66 Abeta 66 beta amyloid proteins 65 Abeta# 65 β amyloid 65 mutant protein 65 alpha synuclein 64 protein clumps 64 amyloid beta proteins 64 misfolded proteins 63 tau 63 amyloid β 62 ß amyloid 62 mutant huntingtin 62 amyloid peptides 62 Beta amyloid 62 Aß 62 gamma secretase 62 mutated protein 62 progranulin 61 toxic beta amyloid 61 ADDLs 61 Alu RNA 61 amyloid ß 61 lipofuscin 61 toxic amyloid beta 61 Amyloid beta 61 ceramide 61 protein fragment 61 nicotinic receptors 61 neuritic plaques 60 clusterin 60 beta amyloid peptides 60 alpha synuclein protein 60 tau aggregates 60 misfolded 60 fatty plaques 60 amyloid peptide 60 Lewy bodies 60 Amyloid 60 protein tangles 60 Amyloid plaques 60 SOD1 60 RANKL 60 uric acid 60 ABCA1 60 BACE1 60 Aβ# 59 Amyloid Beta 59 acetylcholine 59 neurodegeneration 59 Aâ 59 pathological hallmark 59 abnormal tau 59 phosphorylated tau 59 microglial cells 59 beta amyloid fragments 59 eosinophils 59 motor neuron degeneration 59 Alzheimer pathology 59 osteopontin 59 beta catenin 59 glutamate 59 huntingtin protein 58 fibrils 58 TGF β 58 Wnt pathway 58 amyloid deposition 58 scavenger cells 58 atherosclerotic plaques 58 Alzheimer disease pathology 58 EZH2 58 NMDA receptors 58 ERK2 58 sortilin 58 microglia 58 fatty substances 58 atherosclerosis 58 amyloid fibrils 58 amyloid protein plaques 58 macrophages 58 LDL receptor 58 FTLD 58 abnormal clumps 58 NKT cells 58 Skp2 58 protein kinase C 58 Th# cells 58 glutamate receptors 58 myelin 58 atherosclerotic plaque 58 oligomers 57 gliosis 57 PGE2 57 osteoclast 57 microglial 57 TGF beta 57 senescent cells 57 cerebrospinal fluid CSF 57 neuronal cell 57 beta amyloids 57 tumor suppressor protein 57 soluble beta amyloid 57 insoluble plaques 57 CatB 57 antioxidant enzyme 57 low density lipoproteins 57 Nrf2 57 sporadic ALS 57 apoE 57 serine protease 57 ERK1 2 57 amyloid precursor protein 57 TSP1 57 excitatory neurotransmitter glutamate 57 PrP 57 NMDA receptor 57 disulfide bond 57 immune cells 57 synaptogenesis 57 stromal cells 57 adipocytes 57 SGK1 57 micro RNAs 57 proteoglycan 57 COX enzymes 56 microglial activation 56 GSK3 56 synuclein 56 nerve cells 56 neuroligin 56 neuronal dysfunction 56 leukemic cells 56 B lymphocytes 56 amyloid β peptide 56 TSLP 56 demyelination 56 Abeta peptide 56 huntingtin 56 caspase activation 56 acetyl groups 56 caspases 56 secretase 56 abnormal prion protein 56 cyclic GMP 56 myelin sheath 56 apoptotic cells 56 neuronal degeneration 56 Smad7 56 Akt 56 glial cells 56 T lymphocytes 56 neurotransmitter acetylcholine 56 protein alpha synuclein 56 FGFR1 56 arterial plaque 56 autoantibodies 56 PDGFR 56 proteins 56 mutant proteins 56 inflammatory cytokines 56 cannabinoid receptors 56 VEGF receptor 56 angiotensin 56 phagocytosis 56 UCP1 56 vascular endothelial cells 56 neuroblastoma cells 56 CXCL# 56 glycolipids 56 HDAC2 56 chylomicrons 56 Schwann cells 56 Akt1 56 retinoic acid 56 lipids 56 uric acid crystals 56 receptor subtype 56 beta catenin protein 56 fatty acid synthase 55 enzyme aromatase 55 reactive oxygen species 55 neurotransmitter glutamate 55 NF kB 55 calpain 55 neuron degeneration 55 bacterial enzyme 55 integrin 55 serotonin receptor 55 neuroinflammation 55 apoE4 55 selective inhibition 55 Amyloid Precursor Protein 55 nicotinamide 55 FDDNP 55 eicosanoids 55 superoxide dismutase 55 drusen 55 SMN protein 55 NPC#L# 55 FGFs 55 EphA2 55 signaling molecule 55 superoxide 55 fibrous tangles 55 pRb 55 LRP6 55 glioblastoma cells 55 Hsp# [001] 55 synapse formation 55 hematopoietic cells 55 autophagy 55 endoplasmic reticulum stress 55 insoluble protein 55 myeloma cells 55 frataxin 55 oligodendrocytes 55 amyloid formation 55 Cyclin D1 55 PPARγ 55 enzyme beta secretase 55 galanin 55 atherosclerotic lesions 55 neurotransmission 55 c myc 55 astrocytes 55 activin 55 glucocerebroside 55 Neutrophils 55 lymphoid tissue 55 myofibroblasts 55 abnormal proteins 55 endogenous cannabinoids 55 cellular metabolism 55 NR2B subunit 55 TET2 55 PIP3 55 amyloid fibers 55 transmembrane protein 55 substantia nigra 55 LKB1 55 bile acid 55 lymphocytes 55 prion proteins 55 cholinergic neurons 55 von Willebrand factor 55 retinal cells 54 endothelial progenitor cells 54 lipid peroxides 54 CCR3 54 amyloid beta plaque 54 palladin 54 OGG1 54 phenylalanine 54 nerve degeneration 54 morphogen 54 IL #p# 54 mutant SOD1 54 proinflammatory cytokines 54 BMP signaling 54 MDM2 54 CD#L 54 SIRT3 54 GABAergic interneurons 54 Notch1 54 genes encode proteins 54 porphyrins 54 osteocalcin 54 collagen VI 54 TGF beta pathway 54 MAPK pathway 54 brain derived neurotrophic 54 muscular dystrophies 54 MUC1 * 54 hedgehog pathway 54 fatty plaque 54 cardiac fibroblasts 54 DISC1 54 p#NTR 54 PPAR gamma 54 Dr. Bezprozvanny 54 mesenchymal cells 54 TGF beta signaling 54 hyperactivation 54 chaperone protein 54 urate 54 effector functions 54 myo inositol 54 Abeta protein 54 neurotrophic factor 54 catenin 54 apoptotic 54 E cadherin 54 fatty acid oxidation 54 VEGF 54 neuromuscular junction 54 miR# 54 activated microglia 54 goblet cells 54 antioxidant enzymes 54 enzymatic activity 54 polyamines 54 phosphorylated 54 AGEs 54 arginase 54 mitochondrial dysfunction 54 TMEM#B 54 tau protein tangles 54 pyrimidine 54 ptau 54 synaptic function 54 vesicle 54 oxidized lipids 54 SOD1 protein 54 mutant huntingtin protein 54 fibrillin 1 54 cyclins 54 glycoproteins 54 neuroligins 54 anthrax toxin 54 progerin 54 oncoprotein 54 acyl CoA 54 renal fibrosis 54 cardiac myocytes 54 prion protein 54 dendritic spines 54 miR #a [002] 54 SIRT1 gene 54 intestinal epithelium 54 focal adhesions 54 reductase 54 fibrotic 54 suppressor cells 54 aP2 54 Htt 54 secretory pathway 54 cystine 54 neurite outgrowth 54 LIS1 54 glycosaminoglycans 54 hippocampal neurons 54 ACh 54 tenascin C 54 lymphatic vessels 54 tumor suppressor 54 TAp# 54 protein 54 BRAF gene 54 opiate receptors 54 serotonin receptors 54 reactive oxygen 54 adhesion molecule 54 atherogenesis 54 pDCs 54 nitric oxide synthase 54 glial scar 54 HDL particles 54 ACAT2 54 misfolded protein 54 chromosomal instability 54 cdk5 54 fetal hemoglobin 54 glucocorticoid receptor 54 fibrillar 54 FGF2 54 viral proteins 54 Aß# 54 insulin secreting cells 54 B7 H1 54 ganglioside 54 IL 1beta 54 microRNA molecules 54 plasminogen 54 cholesterol efflux 54 PrPSc 54 F actin 54 vWF 53 TH# cells 53 focal adhesion kinase FAK 53 eNOS 53 HDACs 53 chitinase 53 CCN2 53 factor HGF 53 kalirin 53 MT1 MMP 53 lysosomal 53 metabolic enzymes 53 MAP kinase 53 neuronal plasticity 53 calcineurin 53 prostaglandin synthesis 53 TGF ß1 53 TNFa 53 amyloidogenic 53 FOXO3a 53 CaMKII 53 TNF alpha 53 cytokines 53 cardiolipin 53 naturally occurring protein 53 factor BDNF 53 53 endothelial nitric oxide 53 caveolin 1 53 podocytes 53 dystroglycan 53 STAT4 53 MDSCs 53 osteoclasts 53 aggregated Abeta 53 IgA antibodies 53 uPAR 53 gene p# 53 transthyretin 53 inflammatory cascade 53 SIRT2 53 GRK2 53 LRRK2 53 normal prion proteins 53 cAMP signaling 53 osteoclast activity 53 proto oncogene 53 avidin 53 BRAF protein 53 neurites 53 Smad3 53 endocannabinoids 53 CCR1 53 mTORC1 53 granzyme B 53 Kupffer cells 53 neurofibrillary 53 Osteoclasts 53 adhesion molecules 53 motor neurones 53 TGF ß 53 Wnts 53 heterochromatin 53 glycoprotein 53 neurotransmitter dopamine 53 LDL receptors 53 γ secretase 53 Oxidative stress 53 transcriptional repressor 53 protein kinase 53 p# protein 53 peptides 53 amygdala neurons 53 PGC 1α 53 micro RNA 53 Th2 cells 53 gamma aminobutyric acid GABA 53 melatonin receptor 53 spermidine 53 furin 53 WT1 53 normal prion protein 53 5 lipoxygenase 53 excess glutamate 53 cardiac hypertrophy 53 excitotoxicity 53 FGFR3 53 leukotrienes 53 p# MAP kinase 53 mitochondrial respiration 53 SCD1 53 BMP4 53 Th1 53 PHD2 53 Notch receptor 53 macrophage cells 53 vascular endothelial growth 53 CIB1 53 Vpu 53 epigenetic markers 53 cell signaling pathways 53 oxidative damage 53 Misfolded proteins 53 LXRs 53 Wnt signaling 53 GPR# [002] 53 cohesin 53 histone 53 myeloid derived 53 EphB2 53 dentate gyrus 53 beta1 integrin 53 neurotransmitter GABA 53 cyclic AMP 53 PRDM# 53 biochemical pathway 53 Cdc# 53 autophagic 53 corpus luteum 53 tetramer 53 tumor cells 53 serotonin synthesis 53 coronary plaques 53 SORL1 53 micelles 53 isothiocyanates 53 enzyme 53 phosphatases 53 paxillin 53 glial 53 orexin 53 oxidative stress 53 triphosphate 53 IGF2 53 AMPA receptors 53 NADPH oxidase 53 Pin1 53 IFNg 53 dopamine receptor 53 fibrotic tissue 53 primary cilia 53 hypocretin 53 proNGF 53 paracrine 52 neurotrophic factors 52 B7 H3 52 VEGF vascular endothelial 52 interleukins 52 collagen fibers 52 mitochondrial oxidative 52 amino acid tyrosine 52 pyramidal neurons 52 chaperone proteins 52 calcium oxalate 52 perivascular 52 intracellular 52 hepatocyte growth 52 STAT3 52 C1q 52 peripheral tissues 52 dimerization 52 CXCL5 52 adenosine receptors 52 antibodies 52 huntingtin gene 52 lipid peroxidation 52 SH#B# 52 telomere dysfunction 52 Runx2 52 HDAC 52 proteins misfold 52 E3 ligase 52 neurones 52 presenilin 52 lipid 52 CTGF 52 gene fusions 52 transmembrane domains 52 exocrine 52 integrin receptors 52 gamma tocotrienol 52 neuropeptide Y 52 NFkB 52 HMG CoA reductase 52 invadopodia 52 cysteine 52 tyrosine phosphorylation 52 astrocyte 52 bile acids 52 CB1 receptors 52 TGF b 52 PAK1 52 GPIHBP1 52 allergic inflammation 52 metalloproteases 52 epigenetic modification 52 cytoplasmic domain 52 autoreactive T cells 52 fatty acid synthesis 52 lipoprotein lipase 52 LRP1 52 CCL# 52 JAK2 enzyme 52 IL 1ß 52 Treg cells 52 lipocalin 52 leptin resistance 52 lipoprotein 52 peroxisome 52 prostaglandin E2 52 NRG1 52 nNOS 52 GABAergic neurons 52 ApoE4 52 mesenchymal cell 52 CD# receptor 52 eotaxin 52 cyclin B1 52 chromatin structure 52 glucokinase 52 inhibitory 52 histone protein 52 estrogen receptor alpha 52 adrenal cortex 52 BDNF 52 trypsin 52 nitrotyrosine 52 P. gingivalis 52 vimentin 52 heparan sulfate 52 aromatase 52 proteasomes 52 granulomas 52 BCL2 52 Th2 52 Mcl 1 52 IRAK1 52 glycosylated 52 glia 52 SWI SNF 52 encodes protein 52 uPA 52 matrix metalloproteinases 52 dopaminergic neurons 52 dopamine neurons 52 procaspase 3 52 β catenin 52 TNF α 52 neuronal migration 52 PI3K pathway 52 mitochondrial enzyme 52 ferritin 52 presynaptic 52 proteases 52 UCP2 52 proteolysis 52 PIP2 52 CB2 receptor 52 fucose 52 artery walls 52 beta adrenergic receptors 52 angiotensin II 52 protein tyrosine phosphatase 1B 52 cystic fibrosis transmembrane conductance 52 germinal centers 52 lipoproteins 52 malignant cells 52 adipogenesis 52 Sp1 52 MAPK 52 naturally occurring molecule 52 hyperphosphorylated tau 52 endocannabinoid receptors 52 costimulatory 52 insulin receptors 52 protein misfolding 52 HER2 protein 52 TGFβ 52 MIF protein 52 neutrophils 52 KLF2 52 thrombi 52 synaptic vesicles 52 molecular pathway 52 necrotic core 52 hypermethylation 52 atherosclerotic 52 DNMT1 52 effector cells 52 antioxidant glutathione 52 cathelicidin 52 receptor molecule 52 prions 52 copper zinc superoxide 52 proinflammatory 52 RANK ligand 52 enzyme phosphodiesterase 52 neurogenesis 52 leukocyte adhesion 52 cellular organelles 52 melanoma tumors 52 bone resorption 52 podocyte 52 breast cancer metastasis 52 AT1R 52 cell adhesion molecules 52 tumor microenvironment 52 messenger molecule 52 pyrimidines 52 LDLs 52 oxysterols 52 receptor gene 52 misfold 52 messenger RNAs mRNAs 52 bacterial toxins 52 glucocerebroside primarily 52 Hedgehog pathway 52 Clusterin 52 annexin V 52 osteoblast 52 keratinocytes 52 myelination 52 ubiquitin ligase 52 EGFr 52 γδ T cells 52 myelin fatty substance 52 GRP# 52 pro inflammatory cytokines 52 transgenic mouse model 52 apoC III 52 neurotrophic 52 tumor suppressor gene 52 ApoA1 52 colorectal tumors 52 potent inhibitors 52 synovial cells 52 reactive molecules 52 PPARg 52 non coding RNA 52 cell adhesion molecule 52 fibril 52 cathepsins 51 mitogen activated protein kinase 51 PKMzeta 51 atheroma 51 NR2B 51 SATB1 51 bile salts 51 NPD1 51 serotonin 51 PrPC 51 actin cytoskeleton 51 dynamin 51 N Myc 51 mice lacking 51 HSP# 51 neurodegenerative disorder 51 RhoA 51 estrogen receptors 51 RAS RAF MEK 51 Wnt signaling pathway 51 lipopolysaccharide 51 axons 51 CFTR protein 51 cathepsin B 51 vesicle fusion 51 α synuclein 51 psoriatic plaques 51 arterial walls 51 CALHM1 51 neurodegenerative diseases 51 peroxynitrite 51 androgen receptors 51 glioma cells 51 ARF1 51 nitric oxide 51 plasma kallikrein 51 PCSK9 protein 51 neurons 51 p# pathway 51 superoxides 51 prostate tissue 51 amyloid buildup 51 Th# 51 fibrillin 51 lymphoid 51 ADAMTS# 51 cellular senescence 51 KLF4 51 Darapladib 51 melanin 51 acetylcholine receptors 51 SIRT1 51 mesothelial cells 51 laforin 51 PTP 1B 51 oxidized phospholipids 51 serine proteases 51 excitotoxic 51 epigenetic alterations 51 glutamate receptor 51 PI3 kinase 51 CHD7 51 Fibroblasts 51 SGLT2 51 malignant transformation 51 neuropeptide Y NPY 51 nAChRs 51 Aldosterone 51 tumor suppressor genes 51 ubiquitination 51 caveolae 51 p# gene 51 NF kappaB activation 51 MAO B 51 LDLR 51 beta Amyloid 51 COX2 51 activating mutations 51 glycosylation 51 inhibitory neurotransmitters 51 dimers 51 mitochondrial mutations 51 ADAM# 51 defensins 51 genomic instability 51 suppressor gene 51 anti inflammatory cytokine 51 neural degeneration 51 erythrocytes 51 catalase 51 phagocytes 51 apelin 51 5 HT1A 51 receptor protein 51 mRNA 51 Src 51 HtrA2 51 atherosclerotic lesion 51 adenosine 51 endocrine glands 51 lipid synthesis 51 choroid plexus 51 IFN gamma 51 Ubx 51 lysosome 51 aldose reductase 51 Huntingtin 51 advanced glycation end 51 adiponectin 51 arterial plaques 51 regulates gene expression 51 IgG antibodies 51 enzyme inhibitors 51 proteinase 51 TNFα 51 ubiquitinated 51 mitochondria 51 cell motility 51 tumoral 51 lysosomal enzyme 51 cytokine 51 TNFalpha 51 Fabrazyme treats Fabry disease 51 Uric acid 51 PDE5A 51 microtubule dynamics 51 brain lesions 51 MMPs 51 reperfusion injury 51 FGF# 51 CD# protein 51 neural crest stem cells 51 MEF2D 51 progranulin protein 51 protein synthesis 51 MEF2 51 signaling pathway 51 acetyl CoA 51 dopaminergic 51 neurodegenerative disease 51 acetylation 51 hedgehog signaling 51 gamma oscillations 51 Smurf1 51 fibroblast growth 51 pro inflammatory cytokine 51 Tregs 51 NF kappa B 51 pancreatic cells 51 cell signaling pathway 51 malignant tissues 51 GATA3 51 neuronal function 51 IKKß 51 Th1 cells 51 melanocyte 51 perirhinal cortex 51 vacuoles 51 intestinal mucosa 51 abnormal prions 51 carcinoembryonic antigen 51 phosphorylate 51 nAChR 51 S#K# 51 tubulin 51 biologic pathways 51 interferon pathway 51 TNFR 51 Hh 51 S1P 51 MAP kinases 51 excess uric acid 51 Purkinje cells 51 VEGFR1 51 endothelin 51 p# activation 51 Siglec 8 51 dendritic cells 51 bone morphogenic protein 51 PTEN gene 51 axonal damage 51 PDGF receptor 51 inhibit angiogenesis 51 nitric oxide NO 51 vascular endothelial 51 extracellular signal 51 diseased tissue 51 peroxisomal 51 mTOR 51 ferroportin 51 myelin sheaths 51 TGFbeta 51 cytochrome c 51 Prox1 51 DNA adducts 51 Cdk5 51 TRPV1 receptors 51 Eg5 51 kynurenic acid 51 ERK pathway 51 Dicer 51 proinsulin 51 glycation 51 metastatic lesions 51 cadherin 51 beta globin gene 51 microparticles 51 acetylcholine receptor 51 thioredoxin 51 DARPP 51 Hypoxia Inducible Factor 51 malonyl CoA 51 c MYC 51 LPA1 51 melatonin receptors 51 NF1 51 FMRP protein 51 PPAR γ 51 basal forebrain 51 retinal pigment epithelium 51 dendritic spine 51 E#F# 51 Dpp 51 DHA fatty acid 51 underlying vasculopathy 51 MDMX 51 E selectin 51 dopamine transporter 51 reactive oxygen species ROS 51 antioxidant compounds 51 LTB4 51 neural cells 51 Sonic hedgehog 51 glutathione 51 VSMC 51 PCSK9 51 adrenergic receptors 51 matrix metalloproteinases MMPs 51 alveolar macrophages 51 catechins 51 cholesterol absorption 51 stroma 51 NKG2D 51 iNOS 51 glia cells 51 oncogenic 51 myogenesis 51 vascular calcification 51 fusion protein 51 beta defensins 51 cell nuclei 51 TNF receptors 51 DLX5 51 gastrin 51 Alpha synuclein 51 chromatin remodeling 51 filaggrin 51 HSF1