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(Click for frequent words.) 76 pro apoptotic 74 antiangiogenic 74 antiproliferative 73 potent anticancer 73 anti angiogenic 73 cytoprotective 72 inhibitory effects 72 antiapoptotic 71 selective inhibition 71 potent antiproliferative 71 pro angiogenic 71 anti apoptotic 70 antitumor 70 CCR2 70 antiproliferative activity 70 anti fibrotic 70 potent inhibition 70 ENMD # 70 IL #p# 69 immune stimulatory 69 eNOS 69 vasodilatory 69 induces apoptosis 68 immunomodulating 68 anti atherogenic 68 anti amnesic 68 EGF receptor 68 receptor inhibitor 68 antitumor effects 68 chemopreventive 68 neurotrophic 68 inhibit tumor 68 M1 muscarinic 68 immunostimulatory 67 anticancer activity 67 xenograft models 67 Symadex 67 inhibitory effect 67 SIRT2 67 antiproliferative effects 67 immunomodulatory 67 inhibitory activity 67 c MYC 67 somatostatin 67 #HT#A 67 antimetastatic 67 favorable pharmacokinetic 67 potent neuroprotective 67 immuno modulatory 67 neuro protective 67 adipogenic 67 mTOR inhibitors 67 TGF ß 67 immune modulating 66 NKG2D 66 partial agonist 66 immune modulatory 66 Hsp# inhibitors 66 PI3K Akt 66 inducible nitric oxide synthase 66 microtubule targeting 66 immunoregulatory 66 cyclooxygenase COX 66 CCR9 66 pleiotropic 66 XL# inhibits 66 GRN#L 66 ERK1 2 66 potent antitumor 66 TNF α 66 mitogenic 66 pyrimidine 66 TNFalpha 66 flavopiridol 66 PPARγ 66 immunomodulatory effects 66 induce apoptosis 66 potent anti angiogenic 66 oral prodrug 66 anti tumoral 66 selectively inhibits 66 IAP inhibitor 66 HSP# inhibitor 66 orally administered inhibitor 65 PDGFR 65 selective antagonist 65 potent inhibitory 65 potently inhibited 65 elastase 65 neurite outgrowth 65 CYC# 65 iNOS 65 selective kinase inhibitor 65 deacetylation 65 geldanamycin 65 EGFr 65 VEGF inhibitors 65 OXi# 65 mediated inhibition 65 IL 1beta 65 anti leukemic 65 anticancer 65 osteogenic 65 cyclooxygenase 2 65 milatuzumab 65 alpha7 65 E#F# 65 mitogen activated protein kinase 65 CTGF 65 IL 1β 65 IGF 1R 65 vascular disrupting 65 Cyclin E 65 mTOR mammalian target 65 neuroprotective properties 65 VEGFR2 65 immunomodulator 65 upregulation 65 PTHrP 65 inhibited tumor 65 tumor suppressive 65 potent inhibitor 65 factor HGF 65 selective modulator 65 IL 1ß 65 potent antiviral 65 VEGF induced 65 thrombopoietin 65 anti CD3 65 phosphate S1P 65 γ secretase 65 IFN γ 65 nitric oxide synthase 65 estrogen receptor beta 65 cytotoxic 65 TGF beta1 65 HDAC inhibition 64 TNFα 64 PHD2 64 FGFR 64 ectopic expression 64 HepG2 cells 64 antiinflammatory 64 dephosphorylation 64 CGRP 64 cytotoxicity 64 CTLA 4 64 potent stimulator 64 antiangiogenic activity 64 antitumor effect 64 inhibiting tumor 64 tumorigenicity 64 NFkappaB 64 proapoptotic 64 IGF IR 64 sphingosine 1 64 cytostatic 64 highly selective inhibitor 64 carcinoembryonic antigen 64 NF kappaB activation 64 tubulin polymerization 64 potent inhibitors 64 cyclooxygenase 64 autophagic 64 antitumoral 64 nanomolar range 64 selective agonist 64 PTP 1B 64 5 HT2A serotonin 64 proinflammatory 64 prostaglandin synthesis 64 Aurora kinase 64 erythropoietic 64 antiangiogenesis 64 active metabolite 64 kinase inhibition 64 deacetylase inhibitors 64 prostaglandin E2 64 GSK3B 64 S1P 64 reversible inhibitor 64 ligand TRAIL 64 anti neoplastic 64 serine threonine 64 Xanafide 64 pan HDAC inhibitor 64 inflammatory cytokine 64 potently inhibit 64 vWF 64 enzyme inhibitors 64 #ME# 64 selectively inhibit 64 antitumor efficacy 64 immunomodulation 64 constitutively active 64 neuroprotective 64 orally bioavailable mimics 64 histone deacetylase inhibitor 64 insulin sensitizing 64 PGE2 64 TTR gene 64 novel peptide 64 chemoprotective 64 peroxidase 63 osteoblastic 63 antisense inhibition 63 anti inflammatory cytokine 63 hedgehog pathway 63 muscarinic 63 N methyl 63 CDK inhibitor 63 Factor VEGF 63 PPARgamma 63 vascular disrupting agents 63 lytic 63 peroxisome proliferator activated 63 glucagon receptor 63 cyclin dependent kinase inhibitor 63 potent cytotoxic 63 TLR8 63 acetylcholinesterase AChE 63 adrenoceptor 63 hypoxia inducible factor 63 endothelial nitric oxide synthase 63 VEGF receptor 63 PDGF receptor 63 MMP2 63 CCR1 63 bronchodilatory 63 prostaglandin E2 PGE2 63 VE cadherin 63 SERMs 63 antithrombotic 63 JAK2 63 vivo 63 vascular endothelial cells 63 TNFa 63 cardio protective 63 chemotherapeutic drug 63 receptor subtypes 63 TGF β 63 p# activation 63 antimitotic 63 dose dependently 63 cytokines IL 63 receptor mediated 63 effector function 63 inhibits protein synthesis 63 PDE#A 63 downregulates 63 pathophysiological effects 63 mouse xenograft models 63 muscarinic receptor 63 BAL# [001] 63 AKT1 63 tryptase 63 5 HT1A 63 protein tyrosine phosphatase 1B 63 COX2 63 Preclinical studies suggest 63 endothelial activation 63 antitumour 63 immune suppressive 63 TrkA 63 HDAC inhibitors 63 preclinical models 63 IL #E 63 proteasome inhibitor 63 63 acetylcholine receptor 63 ERa 63 selective inhibitors 63 Imprime PGG 63 transcriptional activation 63 chemotactic 63 IGFBP 3 63 chemopreventive agent 63 gastrin 63 FasL 63 HCV replication 63 AT1R 63 ERalpha 63 cytochrome P# 63 receptor activation 63 selective inhibitor 63 cytochrome P 63 TRAIL induced apoptosis 63 anti angiogenic agent 63 VEGF receptors 63 p# mitogen activated 63 V#F mutation 63 ABCA1 63 tumorigenic 63 ERK pathway 63 Preclinical studies 63 osteoblast 63 neovasculature 62 novel anticancer 62 MT1 MMP 62 anticancer agent 62 GMX# 62 activin 62 cytolytic 62 phosphatidylinositol 3 62 RANK Ligand 62 demonstrated antitumor activity 62 allosteric 62 inflammatory mediators 62 alkylating agent 62 receptor PPAR 62 antioxidative 62 PXD# 62 angiogenesis inhibitor 62 serine protease 62 anti inflammatory cytokines 62 MTP inhibitor 62 LPA1 receptor 62 microglial activation 62 ß catenin 62 CEACAM1 62 Akt activation 62 liposomal formulation 62 B7 H1 62 tenascin C 62 ERK signaling 62 vimentin 62 estramustine 62 signal transduction inhibitor 62 5 HT6 receptor 62 derived neurotrophic factor 62 HGS ETR2 62 Squalamine 62 glucocorticoid receptor 62 lipoic acid 62 biodistribution 62 act synergistically 62 PI3K inhibitor 62 pharmacokinetic interactions 62 costimulation 62 Apoptone 62 MEK inhibitors 62 calcitriol 62 HCV protease 62 E selectin 62 antitumor activity 62 matrix metalloproteinases 62 Cathepsin B 62 PPARg 62 NPD1 62 Tß4 62 histone acetylation 62 Flt3 62 hydrolases 62 potent antitumor activity 62 D aspartate 62 monocyte chemotactic protein 62 interferon IFN 62 cathepsins 62 mineralocorticoid 62 Abl 62 isoproterenol 62 potently inhibits 62 clusterin 62 selective agonists 62 antiarrhythmic 62 antioxidant enzymes 62 HIF 1α 62 NMDA antagonist 62 lysophosphatidic acid 62 cisplatin resistant 62 sphingolipid 62 radioprotective 62 taxol 62 Immunohistochemical analysis 62 Eg5 62 FGFs 62 CCN2 62 ERK activation 62 EP1 receptor 62 immunosuppressive 62 PEDF 62 erythropoietin receptor 62 inverse agonist 62 STAT1 62 depsipeptide 62 acetylcholinesterase 62 vascular disrupting agent 62 GHRH 62 fosbretabulin 62 PPAR peroxisome proliferator activated 62 CA4P 62 autocrine 62 overexpression 62 AKT inhibitor 62 c MET 62 prostanoid 62 secretory phospholipase A2 sPLA2 62 oestrogenic 62 tolerogenic 62 EGFR receptor 62 histone deacetylases 62 imetelstat 62 COX enzymes 62 multitargeted 62 Hedgehog pathway 62 IL6 62 poly ADP ribose polymerase 62 immune modulator 62 receptor agonists 62 Histone deacetylase 62 induced apoptosis 62 proteoglycan 62 factor TNF 62 dopamine D2 62 favorable pharmacokinetic profile 62 multi kinase inhibitor 62 vitro cytotoxicity 62 S/GSK# 62 apoptosis inducing 62 superoxide dismutase 62 investigational humanized monoclonal antibody 62 agonism 62 Inosine 62 Bcl XL 62 5 HT2A receptor 62 Upregulation 62 binds selectively 62 pRb 62 tyrosine hydroxylase 62 liposome encapsulated 61 GPx 61 molecularly targeted 61 siRNA mediated 61 interleukins 61 CBLC# 61 potentiator 61 mRNA expression 61 perivascular 61 oral JAK1 61 nicotinic acetylcholine receptor 61 leukocyte adhesion 61 antifibrotic 61 etoposide 61 thioredoxin 61 cytokine 61 MGd 61 CK2 61 vascular endothelial 61 talabostat 61 Akt 61 heme oxygenase 61 Hedgehog signaling 61 mTOR pathway 61 tumor vasculature 61 Interferon alpha 61 tumor xenograft models 61 triphosphate 61 CD# antibody [001] 61 signaling cascades 61 CD# expressing 61 4E BP1 61 ENaC 61 lymphangiogenesis 61 JAK1 61 nanomolar 61 fatty acid oxidation 61 vitro studies 61 MUC1 61 serotonin reuptake 61 EGFR tyrosine kinase inhibitors 61 thalidomide Thalomid 61 tumoral 61 GAP #B# 61 phosphatases 61 enzyme inhibitor 61 lenalidomide dexamethasone 61 BCL2 61 oncomodulin 61 CD# receptor 61 factor PlGF 61 FK# 61 HIF 1a 61 sulindac 61 rhIL 7 61 Epothilones 61 Clusterin 61 nicotinic 61 5HT 61 fibrinolytic 61 EGFR signaling 61 EpCAM 61 ErbB 61 upregulates 61 cMET 61 tubulin binding 61 thapsigargin 61 lymphoid cells 61 natriuretic 61 amino acid substitutions 61 gemcitabine Gemzar ® 61 Darinaparsin 61 MAP kinase 61 oncogenic transformation 61 apolipoprotein AI 61 5 lipoxygenase 61 HDACi 61 5 hydroxytryptamine 61 heme oxygenase 1 61 HER3 61 mecamylamine 61 leukotriene pathway 61 DFMO 61 related apoptosis inducing 61 CB1 receptor 61 kinase pathway 61 proto oncogene 61 UsiRNAs 61 LTB4 61 Th2 cytokines 61 hepatocyte growth 61 protein tyrosine kinase 61 eotaxin 61 Overexpression 61 oxidative stress inducer 61 thrombin receptor 61 isoenzymes 61 cardioprotection 61 MEK ERK 61 protein kinase inhibitor 61 serine proteases 61 Aß 61 ESBA# 61 nAChR 61 MMP9 61 multikinase inhibitor 61 CYP#B# 61 Fibroblast Growth Factor Receptor 61 heparanase 61 receptor tyrosine kinase 61 CORT # 61 cytokine signaling 61 potent suppressor 61 cardiac repolarization 61 immune modulation 61 CGEN # 61 antidiabetic 61 IL 1Ra 61 cyclic adenosine monophosphate cAMP 61 intracellular accumulation 61 receptor subtype 61 leukotriene 61 fibrotic disease 61 novel VDA molecule 61 neuronal differentiation 61 haematopoietic 61 HDAC 61 cell adhesion molecule 61 small molecule tyrosine 61 metaglidasen 61 CYP #A# 61 integrin receptors 61 pro inflammatory cytokines 61 Etoposide 61 STAT3 61 upregulated 61 neurotrophic factors 61 serotonin receptor 61 Apo2L 61 solithromycin 61 potent antibacterial 61 Akt signaling 61 serine threonine kinase 61 potency selectivity 61 downregulation 61 GPR# [002] 61 Angiolix 61 tyrosine kinase inhibitor 61 lysophosphatidic acid LPA 61 micronuclei 61 Lyn kinase 61 isoenzyme 61 endostatin 61 dimerization 61 bradykinin 61 EGFR HER 61 tyrosine phosphorylation 61 gamma tocotrienol 61 androgen receptor AR 61 receptor CXCR4 61 trans retinoic acid 61 receptor modulator 61 TGF alpha 61 myeloid derived 61 renal fibrosis 61 LRP5 61 Fc receptors 61 upregulating 61 NFkB 61 NF kB pathway 61 HIF 1alpha 61 serotonergic 61 GRP# 61 proteolytic enzymes 61 Th1 type 61 polyamine 61 inhibit angiogenesis 61 HDAC2 61 P#X# receptors 61 Kupffer cells 60 secreted protein 60 radiolabeled 60 intracellular uptake 60 cathepsin B 60 cyclin E 60 P selectin 60 alpha#beta# integrin 60 NF κB 60 pDCs 60 interleukin IL -# 60 ERK1 60 IGF1R 60 gamma secretase 60 cytosolic 60 transactivation 60 anti mitotic 60 vasodilatation 60 HCV replicon 60 HER2 receptor 60 bactericidal activity 60 PLK1 60 JAK inhibitors 60 parathyroid hormone PTH 60 forskolin 60 CD# monoclonal antibody 60 molecule interleukin 60 platelet adhesion 60 mitogen 60 vinblastine 60 TNF receptors 60 Yap1 60 aberrantly activated 60 cyclin dependent kinases CDKs 60 colon carcinoma 60 cytokine IL 60 incretin 60 EGFR HER2 60 caveolin 1 60 vorinostat 60 bioactive lipids 60 RRM1 60 5 HT2B receptor 60 Panzem R 60 osteoclast 60 bleomycin 60 5 HT4 receptor 60 peptide hormone 60 fibrotic 60 targeting CD# 60 miR #a [002] 60 plasma lipid 60 inhibiting telomerase 60 H#K#me# 60 humoral antibody 60 Pathway Inhibitor 60 HBx 60 indibulin 60 bortezomib Velcade 60 ACh 60 potent anti oxidant 60 ERBB2 60 extracellular signal 60 Wnt#b 60 CXB# 60 costimulatory 60 peripherally acting 60 pegylated liposomal doxorubicin 60 5 HT2A inverse 60 Myolimus 60 chemokine receptor 60 seliciclib 60 muscarinic receptors 60 HMG CoA reductase inhibitors 60 myocyte 60 MDR1 60 IFN α 60 paracrine 60 antibody cytokine 60 oral bioavailability 60 TLE3 60 ERK phosphorylation 60 methyl D aspartate 60 RANK ligand 60 factor Xa 60 inhibits tumor 60 EphA2 60 fibrin deposition 60 receptor tyrosine kinase inhibitor 60 proteasome inhibitors 60 apoptosis induced 60 FGFR2 60 1α 60 TIMP 1 60 neuronal dysfunction 60 erythropoiesis 60 ErbB2 60 neuronal nitric oxide synthase 60 DNMT1 60 apoptotic pathway 60 preclinically 60 bortezomib Velcade ® 60 GSK 3ß 60 decarboxylase 60 superoxide dismutase SOD 60 lymphotoxin 60 3 carbinol 60 ligand induced 60 androgenic 60 AAG geldanamycin analog 60 type glutamate receptor 60 Aplidin 60 MCF7 60 1beta 60 nucleoside analogs 60 orally bioavailable 60 tropomyosin 60 NS#/#A protease 60 cyclic AMP 60 BRAF kinase 60 FGFR4 60 A3 adenosine receptor 60 human tumor xenografts 60 angiogenic 60 kallikrein 60 Notch1 60 tumorigenesis 60 peroxynitrite 60 B7 H4 60 P cadherin 60 mTOR signaling 60 XmAb# 60 receptor gamma 60 HMG CoA reductase 60 mGluR2 NAM 60 p# MAP kinase 60 effector memory 60 ER alpha 60 GRK2 60 S#A# [002] 60 VEGF 60 telomerase inhibitor 60 M2PK 60 MAPK 60 experimental autoimmune encephalomyelitis 60 peripheral blood mononuclear 60 Notch pathway 60 carbohydrate polymer 60 intercellular signaling 60 matrix metalloproteases 60 Tissue Factor 60 NFκB 60 oncogenic 60 PC# cells 60 potentiating 60 inflammatory cytokines 60 CXCR7 60 IFN gamma 60 p# MAPK 60 BZL# 60 peptibody 60 TRPV1 receptors 60 tyrosine kinase 60 immunoreactivity 60 osteoblast differentiation 60 EGFR pathway 60 glial cell 60 Skp2 60 enzymatic activity 60 naturally occurring molecule 60 itraconazole 60 splice variants 60 Gleevec resistant 60 intracellular protein 60 glucokinase 60 CaM 60 remyelination 60 systemically administered 60 MET VEGFR2 60 PI3 kinase 60 humanized antibody 60 PSMA ADC 60 miR #a [001] 60 CYP#A# CYP#D# 60 effector functions 60 pigment epithelium derived 60 Pterostilbene 60 FGF receptor 60 Anticalins ® 60 Wnt signaling pathway 60 mimetics 60 VEGFR1 60 Wnt signaling 60 p# alpha [001] 60 Protelos R 60 inhibit tumor angiogenesis 60 HMG CoA reductase inhibitor 60 1alpha 60 AChE 60 Aβ 60 LY# [002] 60 PI3K/AKT 60 PKCi 60 obatoclax 60 thermosensitive 60 receptor kinase 60 beta adrenergic 60 cytokine interleukin 60 Rho GTPase 60 triterpenoids 60 INGN 60 Aplidin R 60 CD# CD# 60 degranulation 60 PKM2 60 OMP #M# 60 IFN β 60 chemotherapeutic agent 60 fast skeletal troponin 60 5 HT2A 60 subtype selective 60 peptidic 60 pharmacodynamic PD 60 vinca alkaloid 60 collagenase 60 glutamate receptors 60 erlotinib Tarceva ® 60 triglyceride lowering 60 redox active 60 TNFR 60 DiLA2 liposomes 60 IgG1 60 VEGF protein 60 neuroprotective effects 60 somatostatin receptors 60 JAK#/JAK# 60 Seliciclib 60 replicon 60 calcitonin gene related 60 thromboxane A2 60 erlotinib Tarceva 60 ErbB receptors 60 angiotensin II receptor 60 endothelin receptor 60 miR #b [002] 60 YONDELIS 60 thyroid hormone receptor 60 cyclase 60 N cadherin 60 microtubule inhibitor 60 interleukin IL -6 60 HDAC enzymes 60 cyclin D1 60 triggers apoptosis 60 glycolipids 59 naturally occurring amino acid 59 RNA antagonist 59 amyloid β 59 Epidermal Growth Factor Receptor 59 trodusquemine 59 HSP# 59 partial agonists 59 modulatory 59 peptide antigens 59 transcriptional regulation 59 Taxol ® 59 Cloretazine R 59 pharmacokinetic properties 59 Tyrima 59 delta isoform 59 cystic fibrosis transmembrane conductance 59 delafloxacin 59 MAPK pathway 59 histone deacetylase 59 receptor partial agonist 59 ellagitannins 59 glutathione peroxidase 59 IFN alpha 59 β catenin 59 cyclic nucleotide 59 HER2 neu 59 mineralocorticoid receptor 59 epithelial cell 59 phosphoinositide 3 59 isotypes 59 Schisandrin B 59 hydrolytic 59 receptors PPARs 59 contractility 59 olmesartan 59 cis retinoic acid 59 tumor vascularization 59 small molecule defensin 59 oleanolic acid 59 ligand binding 59 KLF4 59 endothelin 59 mTOR inhibition 59 chimeric monoclonal antibody 59 proinflammatory cytokines 59 intracellular signaling 59 thymidine 59 FKBP# 59 microsomal 59 endogenous ligands 59 pharmacokinetics pharmacodynamics 59 proinflammatory mediators 59 HDAC6 59 thymosin beta 4 59 idarubicin 59 radiosensitivity 59 xenograft tumors 59 ErbB4 59 uricase 59 HDACs 59 proteolytic cleavage 59 Wnt beta catenin 59 DNA hypermethylation 59 GABAergic 59 overactivation 59 cell adhesion molecules 59 Gefitinib 59 cleavable linker 59 isoform selective 59 cardioprotective effects 59 bone morphogenic protein 59 VIPR2 59 decitabine 59 CYT# potent vascular disrupting 59 AMACR 59 Raf MEK ERK 59 Y2 receptor 59 adrenergic 59 cyclic peptide 59 synthase TS 59 Fc fusion protein 59 acadesine 59 MEK1 59 alpha 2A adrenergic 59 MAP kinases 59 pharmacodynamic profile 59 antiresorptive 59 ubiquitin ligases 59 chitinase 59 targeted antifolate 59 CCL# 59 tranilast 59 PAK1 59 ornithine decarboxylase 59 transient receptor 59 potent inducer 59 glutathione GSH 59 adenosine receptor 59 SOCS3 59 cytotoxic effects 59 demethylating agents 59 sunitinib Sutent ® 59 Immunohistochemical staining 59 Adenosine 59 kinase inhibitor 59 TRPV4 59 Fc receptor 59 overexpressing 59 resolvins 59 nociceptive 59 p# inhibitor 59 nucleoside analog 59 PEG SN# 59 cholecystokinin CCK 59 CB2 receptor 59 aggrecan 59 adenoviral 59 neurokinin 1 59 cytochrome c 59 vivo efficacy 59 EZN 59 monocyte 59 lipoxygenase 59 FLT3 59 small molecule agonists 59 AT1 receptor 59 tumor regressions 59 drug zotarolimus 59 TGF β1 59 IGFBP7 59 S#P# 59 p#NTR 59 BMP signaling 59 miRs 59 osteoconductive 59 receptor blockers