Related by context. All words. (Click for frequent words.) 76 apoptotic cell 70 apoptosis 69 neuronal cell 68 apoptotic 67 induce apoptosis 66 apoptotic pathway 66 excitotoxic 65 triggers apoptosis 64 induces apoptosis 64 ERK1 2 64 induces apoptosis programmed 64 TGF beta pathway 63 anti apoptotic 63 c MYC 63 endoplasmic reticulum stress 63 prostaglandin synthesis 63 CTGF 63 potent inducer 63 JAK2 enzyme 62 synovial cells 62 caveolin 1 62 cellular senescence 62 TGF b 62 signaling cascades 62 renal fibrosis 62 fainting lightheadedness 62 selective inhibition 62 apoptosis induced 62 Skp2 62 factor PlGF 62 mitotic catastrophe 62 NFkappaB 62 MAPK pathway 62 triggers apoptosis programmed 62 autophagic 62 cyclin E 62 dephosphorylation 62 fibrogenesis 62 inducing apoptosis 62 mitogen 61 neuronal dysfunction 61 Fas ligand 61 intestinal epithelium 61 neurite outgrowth 61 undergo apoptosis 61 MAP kinase 61 TNFa 61 overactivation 61 inducible nitric oxide synthase 61 fatty acid oxidation 61 pro apoptotic 61 NFκB 61 BCL2 61 potent cytotoxic 61 Alu RNA 61 cytolytic 61 acinar 61 tumorigenesis 61 mTOR pathway 61 microtubule dynamics 61 myofibroblast 61 EZH2 61 IL #p# 61 PI3K/Akt pathway 61 prostaglandin E2 PGE2 61 oncoprotein 60 β catenin 60 Smad3 60 mTOR signaling 60 kinase pathway 60 tau phosphorylation 60 Clusterin 60 c myc gene 60 NF kappaB 60 VEGF induced 60 leukotriene pathway 60 hyperactivated 60 cytoprotective 60 heme oxygenase 60 chondrocyte 60 dopaminergic neurons 60 pro inflammatory cytokines 60 potently inhibited 60 tumor suppressor protein 60 mitogen activated protein kinase 60 inhibiting tumor 60 neurotransmitter glutamate 60 STAT3 signaling 60 phosphatidylinositol 3 60 pyruvate kinase 60 microvascular endothelial cells 60 retinoic acid receptor 60 MAP kinases 60 axonal degeneration 60 fast skeletal troponin 60 amyloid β 60 TGF alpha 60 IL 1β 60 IGF 1R 60 activated lymphocytes 60 Akt signaling 60 androgen receptor AR 60 vascular endothelial cells 60 Hedgehog signaling 60 gastrin 59 cathepsins 59 elastase 59 activate p# 59 anti apoptotic proteins 59 tumor vasculature 59 inflammatory cytokine 59 4E BP1 59 ubiquitination 59 apoptotic pathways 59 alpha#beta# 59 pRb 59 neuronal apoptosis 59 cyclic AMP 59 protein tyrosine phosphatase 1B 59 ERK pathway 59 thymidylate synthase TS 59 HIF 1a 59 Oncogenic 59 cell signaling pathway 59 Apoptosis 59 intestinal epithelial cells 59 receptor gamma 59 NF κB 59 fibrin deposition 59 cytochrome c 59 EGF receptor 59 cyclic AMP cAMP 59 cell lysis 59 effector functions 59 specific lectin receptors 59 inflammatory mediators 59 PGE2 59 induce apoptosis programmed 59 paracrine 59 Fibroblast Growth Factor Receptor 59 basophils 59 NF kappaB activation 59 TORC2 59 hormone angiotensin 59 autocrine 59 FasL 59 E#F# 59 interleukins 59 effector function 59 podocyte 59 lung fibrosis 59 T lymphocyte 59 transthyretin 59 mesenchymal cell 59 Caspases 59 autophagy 59 intimal hyperplasia 59 deacetylation 59 IAP inhibitor 59 regulates gene expression 58 NKT cell 58 ligand TRAIL 58 GSK3 58 factor HGF 58 intracellular accumulation 58 spermidine 58 cell motility 58 protein kinase C 58 heme oxygenase 1 58 glutamate receptors 58 antioxidant enzyme 58 Factor VEGF 58 tumor metastasis 58 reactive oxygen species ROS 58 osteoblast 58 mitochondrial biogenesis 58 polyamines 58 adipogenesis 58 mitochondrial respiration 58 TTR gene 58 matrix metalloproteinases 58 VEGF receptor 58 enzyme caspase 58 FGFR3 58 endosomal release 58 LRP5 58 mediated apoptosis 58 phagocytosis 58 PI3K pathway 58 Rab5 58 inhibits tumor 58 V#F mutation 58 cytokine receptor 58 proliferative diseases 58 ImmunoGen DM1 cancer 58 proto oncogene 58 p# activation 58 γ secretase 58 superoxide dismutase 58 related apoptosis inducing 58 extracellular signal 58 NKG2D 58 mitogenic 58 HDAC inhibition 58 pathophysiological effects 58 HER pathway 58 prostaglandin D2 58 IL 1ß 58 clusterin 58 eNOS 58 tumorigenic 58 Vascular Endothelial Growth 58 p# MAPK 58 ERK signaling 58 JNK activation 58 MAP kinase pathway 58 catabolism 58 caspase activation 58 cardiomyocyte 58 synaptogenesis 58 phosphate S1P 58 topoisomerase II 58 toxic misfolded proteins 58 oligodendrocyte 58 failure osmotic nephrosis 58 TNFR 58 Hypoxia Inducible Factor 58 MMP2 58 TGF ß1 58 Aâ 58 ONCONASE triggers apoptosis 58 biochemical cascade 58 osteoclast 58 MAPK 58 MDSCs 58 IFN γ 58 iNOS 58 inhibit angiogenesis 58 prostaglandin E2 58 sphingosine 1 58 renal dysfunction acute renal 58 integrin receptors 58 histone acetylation 58 osteoclast activity 58 ERK phosphorylation 58 tumor cells 58 mediated inhibition 58 polyamine 58 anti inflammatory cytokine 58 cirrhosis liver failure 58 myelofibrosis polycythemia vera 58 cyclooxygenase 2 58 Aβ 58 neuronal differentiation 58 lipogenesis 58 oligodendrocyte progenitor cells 58 synaptic transmission 58 RANKL 58 RAS RAF MEK 58 cytotoxins 58 reactive oxygen species 58 proinflammatory cytokines 58 senescent cells 58 caspases 58 PPARg 58 SIRT3 58 TRAIL receptors 58 GRNOPC1 contains 58 MEK ERK 58 metabolic enzymes 58 CLL cells 58 cytokine signaling 57 osteoclast formation 57 proteolysis 57 UCP2 57 GABAergic 57 DNA intercalator 57 cAMP signaling 57 fibrotic 57 poly ADP ribose polymerase 57 lysyl oxidase 57 endothelial nitric oxide synthase 57 tumor vascularization 57 keratinocyte 57 NF KB 57 cholecystokinin CCK 57 GLI1 57 RANK ligand 57 eicosanoid 57 sPLA2 57 platelet activation 57 atherogenesis 57 excitatory neurotransmitter glutamate 57 tubulin binding 57 JNK pathway 57 fibrotic disease 57 effector cells 57 apoptotic cells 57 Oxidative stress 57 LDL receptor 57 5 FU cytotoxic 57 P glycoprotein 57 Upregulation 57 leukemic cells 57 IGF IR 57 NFAT 57 genotoxic stress 57 mutant huntingtin protein 57 c MET 57 tau aggregates 57 serine protease 57 upregulates 57 intracellular pathways 57 inhibiting enzymes 57 Wnt signaling 57 IL 1beta 57 activin 57 serine threonine 57 leukocyte adhesion 57 leukemic cell 57 endothelial nitric oxide 57 angiogenesis 57 mutant p# 57 neuroinflammatory 57 GABAA receptors 57 upregulating 57 TRAIL induced apoptosis 57 mTORC1 57 SIRT2 57 hyperphosphorylation 57 serine proteases 57 gastrointestinal stromal tumors GISTs 57 COX enzymes 57 EGFR tyrosine kinase inhibitors 57 lysosomal 57 novel peptide 57 trophoblasts 57 epithelial cell 57 Cyclin D1 57 cisplatin resistant 57 antibody mediated 57 pancreatic colon 57 neurofibrillary tangles 57 microglial activation 57 lung epithelium 57 thyroid hormone receptor 57 Notch1 57 TSLP 57 hedgehog pathway 57 myofibroblasts 57 leukaemic stem cells 57 Cathepsin B 57 signaling pathways 57 phagocyte 57 motor neuron 57 apoptosis proteins 57 Wnt pathway 57 NF kB pathway 57 RhoA 57 CYP3A 57 monocytes macrophages 57 kidney urologic 57 p#Kip# 57 mRNA translation 57 apoptosis inducing 57 p# MAP kinase 57 transmembrane receptor 57 histone deacetylation 57 transgene expression 57 phosphorylates 57 cytotoxic effects 57 RUNX3 57 enzyme aromatase 57 transcriptional activation 57 TGF beta1 57 pro inflammatory cytokine 57 VE cadherin 57 redox active 57 vessel constriction 57 FGFR2 57 antioxidant enzymes 57 aberrantly activated 57 agonist induced 57 cellular metabolism 57 calcineurin 57 granzyme B 57 humanized monoclonal antibodies 57 TNFalpha 57 amyloid deposits 57 COX2 57 Akt activation 57 inflammatory cytokines 57 acadesine 57 polymorphonuclear leukocytes 57 PKC isoforms 56 chemokine SDF 1 56 proteosome 56 STAT3 56 EGFR pathway 56 adipogenic 56 messenger molecule 56 intracellular signaling 56 HDAC2 56 TRAIL R2 56 induced neuronal 56 lytic 56 downstream effectors 56 M2 subunit 56 thromboxane A2 56 platelet adhesion 56 UsiRNAs 56 insulin sensitizing 56 intracellular proteins 56 SETDB1 56 cAMP 56 bone morphogenetic proteins BMPs 56 invadopodia formation 56 cyclin B1 56 neutrophil infiltration 56 histone deacetylases 56 peroxisome 56 suppressor cells 56 immune modulator 56 CDK5 56 lymphoid organs 56 antiproliferative activity 56 glucagon receptor 56 glial cell 56 neuronal degeneration 56 pancreatic islet 56 beta amyloid peptide 56 autoreactive T cells 56 selectively inhibited 56 Pim kinases 56 Wnt beta catenin 56 leukemic stem cells 56 PDE4 56 SCD1 56 receptor subtype 56 Bcl xL 56 chemoresistance 56 aberrant activation 56 downregulation 56 osteopontin 56 ABCA1 56 melanocyte 56 acetylcholinesterase AChE 56 Vpr 56 HIF 1α 56 VEGF protein 56 LPA1 receptor 56 catenin 56 cytoskeletal 56 receptor PPAR 56 WT1 56 Cdc7 56 TGF β 56 Wnt signaling pathway 56 osteoprotegerin 56 LTB4 56 malignant transformation 56 molecular signaling pathway 56 cyclic adenosine monophosphate cAMP 56 fibrinolytic 56 phosphoinositide 3 56 enzymatic pathways 56 ß amyloid 56 effector T 56 endothelial activation 56 costimulation 56 cyclooxygenase 56 Treg cells 56 podocytes 56 constitutive activation 56 abnormal angiogenesis 56 tumor suppressor gene 56 PPAR γ 56 myeloma cells 56 hepatic glucose production 56 CD# monoclonal antibody 56 potent antiproliferative 56 5 lipoxygenase 56 Mcl 1 56 aldose reductase 56 superoxides 56 immunomodulatory effects 56 small molecule inhibitors 56 oxidative stress inflammation 56 mutant SOD1 56 tumor angiogenesis 56 gene p# 56 potently inhibit 56 MyoD 56 cardiac contractility 56 oxidant stress 56 amyloid beta plaques 56 HIF 1alpha 56 proliferative disorders 56 intercellular communication 56 Treg cell 56 cell signaling pathways 56 β cells 56 cytotoxic 56 secreted protein 56 TET2 56 intracellularly 56 C5aR 56 tumoral 56 CD#L 56 glucocorticoid receptor 56 PPARγ 56 malignant cells 56 Oct4 promoter 56 Nrf2 56 EphB2 56 c myc 56 GPC5 56 erlotinib Tarceva 56 proapoptotic 56 beta adrenergic 56 focal adhesion kinase FAK 56 hypoxia inducible factor 56 adhesion molecule 56 oncogenesis 56 Raf MEK ERK 56 Pten 56 enzyme AMPK 56 eIF4E 56 anti amnesic 56 β amyloid 56 mevalonate 56 vasodilatation 56 nitric oxide synthase 56 Src 56 breast cancer metastasis 56 sphingolipid 56 CRAC channel 56 super oxide dismutase 56 mitochondrial depolarization 56 β cell 56 angiotensin II hormone 56 antiapoptotic 56 caspase inhibitors 56 dihydrofolate reductase 56 Rap1 56 leukaemic cells 56 Platelet Derived Growth 56 lipid synthesis 56 autophagic cell death 56 downregulating 56 HIF1 56 cyclin dependent kinase inhibitor 56 Nedd4 56 collagen synthesis 56 upregulation 56 hepatic stellate cells 56 receptor mediated endocytosis 56 demethylating agents 56 chemotherapeutic drugs 56 oxidases 56 ryanodine receptor 55 NPD1 55 cyclooxygenase COX 55 activated microglia 55 neurotrophic factors 55 PDGFR 55 pyrimidines 55 cellular pathways 55 triphosphate 55 intracellular 55 suppresses tumor 55 RANK Ligand 55 excess glutamate 55 intracellular protein 55 ketone bodies 55 c Src 55 tumor suppressor proteins 55 PAK1 55 induced apoptosis 55 natriuresis 55 NKX#.# 55 frataxin 55 intercellular signaling 55 NF kB activation 55 lipid peroxides 55 ErbB2 55 NQO1 55 mTOR mammalian target 55 mesenchymal transition 55 FKBP# 55 E3 ligase 55 ectopic expression 55 Fibroblast 55 gluconeogenesis 55 torsade de pointes 55 aminobutyric acid 55 oxidative phosphorylation 55 anionic backbone 55 BCR ABL 55 cyclin dependent kinase 55 tyrosine phosphorylation 55 angiogenic responses 55 TGFbeta 55 peripheral tissues 55 Sp1 55 receptor subtypes 55 Bcr Abl 55 glucokinase 55 vascular inflammation 55 downregulates 55 adrenoceptor 55 neuronal plasticity 55 dimerization 55 steroidogenesis 55 Aß 55 neuromuscular junction 55 HepG2 cells 55 myocyte 55 anti mitotic 55 inhibit viral replication 55 neovascularization 55 inhibiting COX 55 Abeta peptide 55 ACh 55 ceramide 55 PKC alpha 55 colon carcinogenesis 55 Hepcidin 55 breast CSCs 55 PI3K Akt 55 CD#b 55 fatty acid biosynthesis 55 SOD1 55 proinflammatory 55 SGK1 55 PI3K signaling pathway 55 hypermethylation 55 androgen receptor signaling 55 vWF 55 p# alpha [001] 55 intestinal mucosa 55 cathepsin B 55 mTOR 55 TNF α 55 TNFα 55 cirrhosis liver cancer 55 antiangiogenesis 55 posttranslational modification 55 protein synthesis 55 targets Galectin receptors 55 tissue fibrosis 55 excitotoxicity 55 DR5 55 glioma cells 55 tenascin C 55 Src kinase 55 coagulation cascade 55 GABAA receptor 55 cyclin dependent kinases 55 act synergistically 55 MGMT gene 55 cytolytic activity 55 Kupffer cells 55 metalloproteinase 55 species ROS 55 epigenetic alterations 55 signaling pathway 55 microglial 55 S6K 55 microtubule inhibitor 55 DMT1 55 Epstein Barr Virus EBV 55 vinca alkaloids 55 DNA adducts 55 tumorigenicity 55 mesothelial cells 55 neurotransmitter acetylcholine 55 mesothelin 55 acetylcholine receptor 55 cyclic adenosine monophosphate 55 tumor microenvironment 55 erythropoiesis 55 collagen deposition 55 peroxisome proliferator activated 55 muscarinic receptors 55 cell adhesion 55 microtubule destabilizing agent 55 intra tumoral 55 BRAF kinase 55 glycolipids 55 carbohydrate polymer 55 coronary vasodilation 55 radiosensitivity 55 IGFBP7 55 renin angiotensin system 55 chemokines 55 anti CD3 55 drowsiness coma 55 retinal ganglion cell 55 somatostatin 55 paxillin 55 osteogenic differentiation 55 neurotrophic 55 basolateral 55 antitumor immunity 55 systemic antifungal 55 LRP6 55 MAPKs 55 accumulate preferentially 55 PML RARA 55 p#NTR 55 Abeta# 55 molecularly targeted 55 NFkB 55 leukotrienes 55 N cadherin 55 PHD2 55 modulates Akt protein 55 DNA hypermethylation 55 Monocyte 55 matrix metalloproteinases MMPs 55 Oxidative damage 55 IFNg 55 Akt 55 Epidermal Growth Factor Receptor 55 retinal ischemia 55 demyelination 55 casein kinase 55 neuro protective 55 sortilin 55 mitochondrial membrane potential 55 p# Shc 55 neoplastic cells 55 colorectal carcinoma 55 gonadotrophin releasing hormone 55 chromosomal mutations 55 plasminogen 55 receptor mediated 55 PLA2 55 EphA2 55 anthrax toxins 55 mitotic 55 neuronal migration 55 cyclic guanosine monophosphate 55 KLF2 55 recombinant erythropoietin 55 p# pathway 55 chemotherapeutic drug 55 Androgen receptor 55 anti fibrotic 55 HbF 55 interstitium 55 leukocyte 55 Eg5 55 lymphangiogenesis 55 proteoglycan 55 naturally occurring protein 55 neurite 55 inflammatory cascade 55 synapse formation 55 tumor stroma 55 Nitric oxide NO 55 cytostatic 55 GRP# 55 Glucocorticoids 55 pancreatic endocrine 55 cyclic GMP 55 protein CETP 55 protein ubiquitin 55 c Myc 55 E selectin 55 VSMC 55 adrenal cortex 55 antiangiogenic 55 E3 ubiquitin ligase 55 DHFR 55 immunoregulatory 55 cardiac fibroblasts 55 Overexpression 55 cause unconsciousness seizures 55 gamma secretase 55 vascular endothelial 55 receptor inhibitors 55 ErbB3 HER3 55 pro apoptotic proteins 55 CTLA 4 55 cyclin dependent kinases CDKs 55 hormone angiotensin II 55 NMDA receptor 55 toxic amyloid beta 55 EGFR signaling 55 ischemia induced 55 fulminant hepatic failure 55 chronic viral infections 55 Th2 cells 55 serine threonine kinase 55 mitochondrial fragmentation 55 neurturin 55 EP1 receptor 55 ErbB1 55 invading microbes 55 neointimal hyperplasia 55 procaspase 3 55 bcl 2 55 telomerase activation 55 hepatoma 55 underlying vasculopathy 55 HER1 55 EETs 55 Th1 type 55 PDGF BB 55 NF kappaB pathway 55 FADD 54 thyrotropin 54 CYT# potent vascular disrupting 54 proteolytic cleavage 54 Hedgehog signaling pathway 54 #T# L1 54 STAT1 54 amyloid beta peptides 54 catabolic 54 VEGF expression 54 CBLC# 54 catecholamine 54 beta catenin protein 54 myogenesis 54 Epithelial 54 LKB1 54 endothelial cell 54 NF kB 54 p# protein 54 killer NK 54 transdifferentiation 54 plasma kallikrein 54 Angiotensin II 54 neutrophil elastase 54 receptors EGFR 54 pigment epithelium derived 54 thrombopoietin TPO 54 sFlt 1 54 PI3K AKT 54 repolarization 54 pDC 54 siRNA binds 54 PhG alpha 1 54 SIRT1 protein 54 Th1 cells 54 biologic pathway 54 hormone secreted 54 RKIP 54 membrane receptors 54 Notch receptors 54 monocyte derived 54 thymidylate synthase 54 bone metastasis 54 humoral immunity 54 alpha folate receptor 54 tumor suppressor genes 54 genomic instability 54 inhibits protein synthesis 54 lymphotoxin 54 trastuzumab Herceptin ® 54 endosomal 54 Vidaza ® 54 HIF1 alpha 54 mammary cells 54 GABAergic interneurons 54 alpha TNF alpha 54 receptor tyrosine kinases RTKs 54 IFN gamma 54 pDCs 54 toxic beta amyloid 54 TNF alpha 54 BCL#A 54 autoreactive B 54 p#INK#a 54 ubiquitin ligase 54 uPA 54 caspase 54 gene rearrangements 54 cystic fibrosis transmembrane conductance 54 amyloid peptide 54 Protein Kinase C 54 GNAQ 54 neoplastic diseases 54 frataxin gene 54 secretory pathway 54 Notch pathway 54 trophoblast cells 54 kinase PI3K Akt pathway 54 p# INK4a 54 AT1R 54 FGFR1 54 Ras pathway 54 transcriptional repressor 54 endogenous ligands 54 type glutamate receptor 54 oncogenic signaling 54 hippocampal neurogenesis 54 MMAE 54 chloride channels 54 Darapladib 54 isotypes 54 HBV replication 54 insulin secreting 54 Hh pathway 54 cell adhesion molecule 54 oncogenic 54 immuno modulatory 54 osteolytic 54 neuroblastoma cells 54 excess TNF alpha 54 Tumor Necrosis Factor 54 neoplastic transformation 54 HER2 overexpression 54 beta globin gene 54 inhibit oxidative stress 54 SGLT2 54 factor receptor FGFR 54 signal transduction inhibitor 54 chromatin structure 54 estrogen receptor alpha 54 Bcl 2 54 EGFR protein 54 vimentin 54 Aldosterone 54 CYP#B# 54 lymphoid cells 54 Her-2/neu 54 Inappropriate activation 54 insulin secreting beta 54 haematopoietic 54 Integrin 54 ß catenin 54 pancreatic islet cells 54 tau protein 54 protein misfolding 54 superoxide 54 beta secretase 54 epithelial tissues 54 VEGFR 54 FOXO3a 54 antisense inhibitors 54 selectively inhibit 54 PlGF 54 isoenzyme 54 erythropoietic 54 erlotinib Tarceva ® 54 delay bone metastases 54 mTOR inhibitors 54 neurosteroids 54 receptor tyrosine kinase 54 Macrophage 54 organ transplant rejection 54 CDK inhibitor 54 neurotrophins 54 Lp PLA 2 54 CEACAM1 54 insulin secreting cells 54 PPAR alpha 54 proton pump 54 Src kinases 54 cell mediated cytotoxicity 54 signal transduction pathway 54 vinca alkaloid 54 reperfusion injury 54 pharmacological inhibition 54 cyclins 54 peroxidation 54 FGFR4 54 bladder ovarian 54 CaM kinase II 54 potent inhibitor 54 adipocytes fat 54 CDDO Im 54 integrin receptor 54 imatinib Gleevec 54 histone deacetylase HDAC 54 STIM1 54 Phosphorylation 54 Nampt 54 Aurora kinase 54 ERBB4 54 mitochondrial membrane 54 CatB 54 proNGF 54 osteoblastic 54 tyrosine kinase inhibitor 54 hypervascular tumors 54 glucose transporter 54 Leukotrienes 54 ubiquitylation 54 c Fos 54 GPIIb IIIa 54 ABCB1 54 PECAM 54 protein secreted 54 NADPH oxidase 54 ADAMTS#