Related by context. All words. (Click for frequent words.) 73 genomic instability 73 mtDNA mutations 71 p# mutations 71 aneuploidy 71 genotoxic stress 70 p# activation 70 epigenetic silencing 70 de novo mutations 70 Genetic variation 70 HOTAIR 70 malignant transformation 70 telomere dysfunction 70 PTPN# 69 Notch signaling 69 chromosomal rearrangement 69 Cyclin D1 69 transgene expression 69 hypermethylation 69 mitochondrial fusion 69 proteolysis 68 pRb 68 synaptogenesis 68 Genetic predisposition 68 p#NTR 68 renal fibrosis 68 mosaicism 68 microglial 68 shortened telomeres 68 tumorigenesis 68 TGF ß 68 LKB1 68 mitochondrial dysfunction 68 amyloid peptide 68 Foxp3 68 neurite outgrowth 68 SGK1 68 autophagic 68 Prox1 68 epigenetic changes 67 DNMT1 67 somatic mutation 67 CHD7 67 microRNA expression 67 Jhdm2a 67 motor neuron degeneration 67 TGF β 67 ubiquitylation 67 ERK signaling 67 Smad3 67 cyclin E 67 gene rearrangements 67 p# mutation 67 epigenetic alterations 67 podocyte 67 chromosomal aberrations 67 LIS1 67 epigenetic modification 67 STAT4 67 Hedgehog signaling 67 immunoreactivity 67 deacetylation 67 podocytes 66 epigenetic modifications 66 FGFs 66 Leydig cell 66 aldehyde dehydrogenase 66 mitochondrial enzyme 66 LRP6 66 tumor suppressor protein 66 β amyloid 66 neuroinflammation 66 ectopic expression 66 prostate carcinogenesis 66 overactivation 66 melanocyte 66 PTEN protein 66 GLI1 66 PDGFR 66 ß amyloid 66 aneuploidies 66 FGF2 66 PHD2 66 HbF 66 telomerase activity 66 epigenetic markers 66 caspase activation 66 fatty acid oxidation 66 MAPK pathway 66 Pten 66 miRNA expression 66 proto oncogene 66 CD# expression [001] 66 chromosome condensation 66 beta1 integrin 66 MECP2 gene 66 tyrosine phosphorylation 66 transcriptional repression 66 BubR1 66 suppressor gene 66 DNA methylation patterns 66 H#K#me# 66 PARP inhibition 66 tau protein 66 missense mutation 66 telomere shortening 65 telomere maintenance 65 gastric carcinoma 65 SIRT3 65 PTEN gene 65 synapse formation 65 spermatogenesis 65 progranulin 65 miRs 65 Wnt signaling 65 histone acetylation 65 activin 65 fatty acid synthesis 65 ovarian hormones 65 chromosomal rearrangements 65 primary cilia 65 mitochondrial mutations 65 intestinal epithelium 65 VEGF expression 65 neurofibrillary tangles 65 trophoblast cells 65 haematopoietic 65 acinar 65 #BP# 65 OGG1 65 Oxidative stress 65 H#K# [001] 65 NADPH oxidase 65 CEACAM1 65 p#/CBP 65 Aβ 65 familial pancreatic cancer 65 β catenin 65 genomic imprinting 65 miR# 65 tryptase 65 neoplastic 65 VHL gene 65 methylation 65 RIP1 65 antibody mediated 65 p# MAPK 65 osteogenic differentiation 65 TGF b 65 Treg cell 65 synaptic function 65 glycosylation 65 microglial activation 65 alpha synuclein protein 65 FANCD2 65 ADAM# 65 c MYC 65 arterial calcification 65 micro RNAs 65 Clusterin 65 IRF6 65 uPAR 65 p#INK#a 65 NKG2D 65 FMRP protein 65 microdeletion 65 cell motility 65 Cyclin E 65 subcellular compartments 65 missense mutations 65 EBV infection 65 factor PlGF 65 homozygosity 64 mutant proteins 64 HGPS 64 CYP#B# 64 E#F# 64 senescent cells 64 E cadherin 64 S#A# [002] 64 FGFR2 64 LRP5 64 clusterin 64 ARF1 64 FGFR3 64 protein tyrosine phosphatase 64 histone modifications 64 HDAC2 64 epithelia 64 STAT3 signaling 64 transcriptional repressor 64 NFKBIA 64 inherited mutations 64 SMAD4 64 tumorigenicity 64 neuronal dysfunction 64 caveolae 64 HER2 neu 64 familial ALS 64 p#Kip# 64 P cadherin 64 mesenchymal cell 64 adhesion proteins 64 amyloid deposition 64 spontaneous mutation 64 overexpression 64 focal adhesions 64 GRP# 64 TGF ß1 64 atypical hyperplasia 64 HMGA2 64 chromatin structure 64 invadopodia formation 64 BACE1 64 macrophage infiltration 64 cyclin B1 64 Genetic variants 64 airway remodeling 64 monogenic 64 osteopontin 64 palladin 64 acetylation 64 epigenetic mechanisms 64 JAK2 enzyme 64 EGFR signaling 64 colorectal tumor 64 HDAC6 64 BMP signaling 64 hyperinsulinemia 64 DSBs 64 neural crest 64 mutated protein 64 TGFß 64 phenotypic expression 64 PON1 64 MLH1 64 pro angiogenic 64 chromosomal regions 64 phenotypic variation 64 aberrant activation 64 Akt1 64 cohesin 64 MMP9 64 Notch1 64 hedgehog signaling 64 pleiotropic 64 MSH2 64 myofibroblasts 64 gene p# 64 estrogen receptor alpha 64 mutant huntingtin protein 64 oncogenic transformation 64 pancreatic islet 64 autoregulation 64 differential gene expression 64 lymphocyte activation 64 alternatively spliced 64 somatic mutations 64 genetic alterations 64 spontaneous mutations 64 activated microglia 64 neovascularization 64 IL 1ß 64 osteoclast activity 64 Hsp# [001] 64 beta catenin protein 64 epigenetic inheritance 64 BDNF protein 64 amyloid β 64 CDK8 64 prothrombotic 64 platelet activation 64 NQO1 64 cellular senescence 64 carcinogenesis 64 oncogenesis 64 downregulation 64 mutant protein 64 TAp# 64 PEDF 64 ERK2 64 germline mutation 64 ADAMTS# 64 caveolin 1 64 nephron 64 micronuclei 64 constitutively 64 clonogenic 64 basal cell nevus syndrome 64 frataxin 64 chromosomal translocations 64 uPA 64 biochemical abnormalities 64 genetic polymorphism 64 mitochondrial metabolism 64 transthyretin 64 chromosomal translocation 63 systemic inflammation 63 neuroligins 63 atherosclerotic lesions 63 Oxidative damage 63 WNK1 63 vimentin 63 APOL1 63 APOE ε4 63 cell adhesion molecules 63 mitotic progression 63 ADPKD 63 methylation patterns 63 sporadic ALS 63 miRNA genes 63 hyperactivation 63 GSK3 63 neuron degeneration 63 TOP2A gene 63 IDH mutations 63 myelination 63 WT1 63 NFκB 63 histone methylation 63 DNA methylation 63 hyperactivated 63 TMEM#B 63 epithelial barrier 63 iNOS 63 MGUS 63 transcriptional regulation 63 colonic mucosa 63 protein misfolding 63 Cathepsin B 63 receptor kinase 63 lymphoid 63 tumoral 63 excitotoxicity 63 RKIP 63 mRNA expression 63 FUS1 63 c Src 63 Stat5 63 excitotoxic 63 FGF signaling 63 premalignant lesions 63 RUNX3 63 Amino acid 63 neoplastic transformation 63 lymphocytic 63 Bcl xL 63 antioxidant enzyme 63 osteolytic 63 apoC III 63 androgen receptor AR 63 colorectal carcinoma 63 estrogen metabolism 63 nitrotyrosine 63 CNTNAP2 gene 63 PGC 1α 63 lymphangiogenesis 63 ERK1 2 63 TNFα 63 regulated kinase ERK 63 dopamine signaling 63 BMP4 63 DICER1 63 enzymatic activity 63 OPHN1 63 GABAergic interneurons 63 osteoblastic 63 Hh pathway 63 apoE 63 NKX#.# 63 airway hyperresponsiveness 63 prion infection 63 oncogenic 63 cellularity 63 chemoresistance 63 proteoglycan 63 lactate dehydrogenase 63 synuclein 63 Genetic variations 63 mRNA decay 63 ectoderm 63 brain lesions 63 DLX5 63 C EBP alpha 63 secretory pathway 63 nitric oxide synthase 63 nucleoli 63 goblet cells 63 progranulin gene 63 paralogs 63 cAMP signaling 63 cyclin D1 63 GATA4 63 aromatase 63 tumor metastasis 63 TSLP 63 histone modification 63 misregulation 63 chitinase 63 aberrant methylation 63 cardiac myocytes 63 Six3 63 cardiac fibroblasts 63 carcinoembryonic antigen 63 amyloid beta peptides 63 APOE4 63 sphingolipid 63 Skp2 63 Peutz Jeghers syndrome 63 #q#.# [001] 63 γ secretase 63 NR#A# 63 MMP# 63 abnormal proteins 63 breast cancer metastasis 63 cardiac fibrosis 63 Srcasm 63 germline mutations 63 beta amyloid peptides 63 tumor suppressor gene 63 Akt activation 63 PKCi 63 testicular germ cell 63 demethylation 63 collagen VI 63 sequence homology 63 mRNA transcripts 63 COX2 63 myeloperoxidase 63 myocyte 63 CALHM1 63 Aâ 63 osteoclast 63 amyloid deposits 63 posttranslational modifications 63 TET2 63 Hashimoto thyroiditis 63 TCF#L# 63 IGF2 63 CaM kinase II 63 DNA hypomethylation 63 KLF4 63 proapoptotic 63 DNA demethylation 63 TGF beta pathway 63 inducible nitric oxide synthase 63 E3 ubiquitin ligase 63 redox active 63 osteosarcomas 63 Fas ligand 63 Immunohistochemical analysis 63 Hh signaling 63 Akt signaling 63 TGF beta signaling 63 mucinous 63 dephosphorylation 63 colocalization 63 EphB2 63 virulence genes 63 HER2 expression 63 metabolizing enzymes 63 microtubule dynamics 63 myoepithelial 62 UVB induced 62 oncoprotein 62 FGFR1 62 polyamines 62 apoE4 62 GPIHBP1 62 Aß 62 neuronal degeneration 62 PIK3CA 62 amyloidogenic 62 inflammatory cytokine 62 CagA 62 Dpp 62 atherogenesis 62 Smad7 62 NF kB pathway 62 polyadenylation 62 cellular metabolism 62 GSTT1 62 pathophysiological 62 Akt 62 lysosomal 62 ubiquitination 62 synovial cells 62 MT1 MMP 62 NF κB 62 NOD2 62 PKM2 62 cathepsin B 62 p# INK4a 62 Lyn kinase 62 RANKL 62 IGFBP2 62 FGFR4 62 intracellular proteins 62 nAChR 62 phagocytosis 62 mesenchyme 62 cytokine signaling 62 ABCA1 62 myopathies 62 LDL receptor 62 autosomal dominant disorder 62 misfolded protein 62 precursor lesions 62 TXNIP 62 molecular abnormalities 62 BCL2 62 adipogenesis 62 BRAF protein 62 cathepsin K 62 caveolin 62 ADDLs 62 repolarization 62 innate immune responses 62 GRK2 62 oxidant stress 62 ACh 62 histone deacetylases 62 cardiolipin 62 pathogenic mutations 62 TP# gene 62 TNFa 62 alternative splicing 62 Rab5 62 HCV replication 62 genetic alteration 62 NFkappaB 62 polygenic 62 impair fertility 62 tau proteins 62 metalloproteinases 62 regulates gene expression 62 demethylase 62 calcineurin 62 glucokinase 62 oxidized phospholipids 62 deleterious mutations 62 PPAR γ 62 endothelial activation 62 mTOR signaling pathway 62 gene polymorphisms 62 nonsense mutations 62 segmental duplications 62 pancreatic endocrine 62 SIRT1 gene 62 evolutionarily conserved 62 PI3K signaling 62 mutations 62 substrate specificity 62 stem cell pluripotency 62 aneuploid cells 62 hyperplasia 62 gliosis 62 CYP #D# 62 transmembrane receptor 62 chimeric mice 62 eotaxin 62 untreated celiac disease 62 PTEN mutations 62 promoter hypermethylation 62 fatty acid synthase 62 endostatin 62 telomerase activation 62 progerin 62 Rho kinase 62 basal cells 62 neuronal plasticity 62 BCL#A 62 clefting 62 Raf MEK ERK 62 mammographic density 62 IFN γ 62 c myc 62 Wnt pathway 62 perivascular 62 COX enzymes 62 multigenic 62 mesenchymal transition 62 nerve degeneration 62 necrotic core 62 FOXM1 62 ALDH2 62 genetic aberrations 62 transcriptional activation 62 monocyte chemoattractant protein 62 BRAF V#E 62 calcium homeostasis 62 CHI#L# 62 BRAF gene 62 TNFalpha 62 N Myc 62 forkhead 62 epithelial cell 62 GNAQ 62 chromatin remodeling 62 glutamate signaling 62 p tau 62 seminomas 62 APOC3 62 prostate cancer CaP 62 Htt 62 c MET 62 telomere length 62 c Myb 62 fibrillin 1 62 etiologic 62 proinflammatory 62 steroidogenic 62 thyrotropin 62 hippocampal function 62 mammary cancers 62 CCL5 62 cardiomyocyte 62 intracellular signal transduction 62 neural progenitor 62 chromosomal anomalies 62 ZNF# 62 chromosome segregation 62 IKZF1 62 Upregulation 62 transcriptional silencing 62 cell adhesion 62 CTGF 62 mammary cells 62 SETDB1 62 colorectal carcinogenesis 62 pleiotropic effects 62 invadopodia 62 STAT3 62 abnormal prion protein 62 glutathione GSH 62 phenotype 62 APOE e4 62 leukemic cell 62 DGAT1 62 X inactivation 62 miR #a [001] 62 interferon pathway 62 miR #b [001] 62 beta amyloid peptide 62 peroxisome 62 Mcl 1 62 biogenesis 62 FKBP# 62 multidrug resistance 62 chromosomal abnormalities 62 nestin 62 TSC1 62 neural crest stem cells 62 underlying pathophysiology 62 Dysregulation 62 nephrogenic 62 desmosomes 62 hepatic glucose production 62 fetal malformations 62 Genetic mutations 62 TCF#L# gene 62 aneuploid 62 GBM tumors 62 imprinted genes 62 neuronal differentiation 62 protein p# 62 mutant p# 62 beta subunit 62 EphA2 62 Wnt signaling pathway 62 microRNAs miRNAs 62 GATA3 62 unmeasured confounding 62 FMR1 gene 62 acetylcholine receptor 62 non coding RNA 62 Rb gene 62 microdeletions 62 mitochondrial respiration 61 demyelination 61 FGF# 61 microchimerism 61 miR #a [002] 61 luminal cells 61 ADDL 61 cholesterol biosynthesis 61 vascular endothelial cells 61 MC4R gene 61 RAS RAF MEK 61 B7 H3 61 HBx 61 JAK STAT 61 serotonin synthesis 61 TGFβ 61 Folic acid deficiency 61 incidentalomas 61 HER2 overexpression 61 myo inositol 61 metabolic alterations 61 intestinal mucosa 61 RhoA 61 colorectal tumors 61 Runx2 61 epididymal 61 cellular pathways 61 microRNA molecules 61 mediated inhibition 61 XBP1 61 bacterial virulence 61 UCP1 61 hepatic lipase 61 ARNT 61 galanin 61 HMGCR 61 Cdc# 61 receptor activation 61 phenotypes 61 extramedullary 61 DNA rearrangements 61 gene expression patterns 61 Sir2 61 P. gingivalis 61 leukocyte recruitment 61 piRNAs 61 p# pathway 61 amyloid proteins 61 APOE allele 61 prostate epithelial cells 61 C1q 61 oxidases 61 suppressor cells 61 metaplasia 61 neurofibrillary 61 Wnt#b 61 LMNA 61 spermidine 61 SPINK1 61 STAT1 61 adherens junctions 61 Skeletal muscle 61 beta catenin 61 vascular endothelial 61 Nrf2 61 sortilin 61 Ets2 61 familial clustering 61 Leydig cells 61 IDH1 61 filaggrin 61 effector functions 61 antiapoptotic 61 #q#.# [002] 61 NOTCH1 61 Sox9 61 constitutively expressed 61 CFTR gene 61 HepG2 cells 61 glomerular 61 neuronal cell 61 protein kinase C 61 CIB1 61 GABAergic neurons 61 neuronal migration 61 diffusible 61 CPEB 61 lipoprotein lipase 61 amyloid plaque formation 61 Notch pathway 61 IFRD1 61 menin 61 GPx 61 ERBB2 61 MeCP2 gene 61 Purkinje cell 61 MDM2 61 bronchial epithelial cells 61 ERa 61 GLUT1 61 vascular dysfunction 61 S#K# 61 TTR gene 61 apoptosis pathway 61 resistin 61 neural cells 61 CXCL# 61 malignant phenotype 61 Alu RNA 61 centrosome 61 renal cell carcinomas 61 membrane fusion 61 HPA axis 61 xenobiotic 61 Th# cells 61 GSTM1 61 chemosensitivity 61 adipocyte 61 mitogen activated protein kinase 61 TCF4 61 epithelial tissues 61 S6K 61 clonal expansion 61 chimerism 61 mesotheliomas 61 protein tau 61 PPARγ 61 medulloblastomas 61 NKCC1 61 p# Shc 61 microsatellite instability 61 SUMOylation 61 mitotic catastrophe 61 paxillin 61 hepatic stellate cells 61 megakaryocytes 61 leukaemic stem cells 61 adult neurogenesis 61 upregulates 61 RRM1 61 hypomethylation 61 leukocyte adhesion 61 catenin 61 cholesterol homeostasis 61 circadian genes 61 germinal center 61 SFRP1 61 Chronic pancreatitis 61 amyloids 61 Pin1 61 chaperone proteins 61 Src 61 CCN2 61 epigenetic regulation 61 selective inhibition 61 sirtuin enzymes 61 endoplasmic reticulum stress 61 genetic abnormalities 61 SHANK3 61 SMN protein 61 TMPRSS2 ERG fusion 61 misfolding 61 developmental abnormalities 61 nonhereditary 61 periodontal infection 61 proinflammatory cytokine 61 induced neuronal 61 H#K# [002] 61 atherosclerotic lesion 61 molecular pathway 61 immunopathology 61 ubiquitinated 61 Eg5 61 MyoD 61 NKT cell 61 oligomerization 61 heterozygosity 61 telomere lengths 61 Nod1 61 upregulating 61 mutated K ras 61 E selectin 61 myofibroblast 61 folate metabolism 61 NR2B 61 Ras oncogene 61 PrPC 61 G6PD 61 alpha synuclein gene 61 dysregulation 61 protein CETP 61 da mage 61 p# protein 61 tumorigenic 61 renal cysts 61 MAP kinase 61 hypoperfusion 61 PPARg 61 HSF1 61 mitochondrial DNA mutations 61 GSTM1 gene 61 tumor suppressor genes 61 endocannabinoid signaling 61 oncomodulin 61 PKC beta 61 PML RARA 61 divide uncontrollably 61 ERK phosphorylation 61 squamous cell lung cancer 61 fibril formation 61 huntingtin 61 eNOS 61 apoptosis induced 61 ferroportin 61 prodynorphin 61 histological subtype 61 Telomere length 61 cellular prion protein 61 MDSCs 61 oxidative DNA 61 proNGF 61 C. albicans 61 NFkB 61 IL #p# 61 CD4 + CD# 61 male hormone androgen 61 capillary endothelial cells 61 cytoskeletal 61 genetic loci 61 chromosomal mutations 61 CD# expression [002] 61 IGF1 61 osteoblast 61 Cryptococcus neoformans 61 anti apoptotic proteins 61 EZH2 61 neuritic 61 fibrin deposition 61 nodulation 61 amyloid formation 61 CXCL5 61 #p#.# [002] 61 colorectal adenocarcinoma 61 PB1 F2 61 KLF# 61 cypin 61 NKX2 61 rRNA 61 heterozygotes 61 CD8 + 61 MAP kinases 61 chromosomal deletions 61 polyamine 61 cytoprotective 61 clinically insignificant 61 Wnts 61 heparanase 60 humoral immunity 60 presenilin 60 de ath 60 DEAR1 60 phosphorylates 60 cyclin 60 constitutively active 60 NPD1 60 mitochondrial function 60 apoptotic pathway 60 leukaemias 60 procaspase 3 60 KCNE2 60 Phosphorylation 60 FTLD 60 intestinal permeability 60 beta globin 60 catabolism 60 EGFR pathway 60 gene amplification 60 isoenzymes 60 glycolipids 60 inactive X chromosome 60 pre malignant lesions 60 E cadherin expression 60 osteocalcin 60 DUX4 gene 60 underlying molecular mechanisms 60 MTHFR 60 granulocyte 60 Methylation 60 IKKa 60 S nitrosylation 60 cytoskeletal protein 60 leptin receptor 60 sFlt 1 60 pathophysiologic 60 thermodynamic stability 60 endocrine tumors 60 dentate gyrus 60 UCP2 60 pAkt 60 carotid plaque 60 #ß HSD1 60 thioredoxin 60 prognostic marker 60 Chromosomal 60 lymph node metastasis 60 epithelial 60 mTOR signaling 60 ependymal cells 60 glial cell 60 keratinocyte 60 PIP3 60 Abeta# 60 lymphocyte proliferation 60 microvessels 60 arginase 60 inherited predisposition 60 tumor suppressor proteins 60 malignant prostate 60 ligand induced 60 oesophageal adenocarcinoma 60 IFN gamma 60 beta amyloid proteins