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(Click for frequent words.) 76 cytosolic 72 centromeric 71 constitutively 71 presynaptic 71 transcriptional activation 71 ß catenin 70 Rab5 70 β 70 ERK1 2 70 actin 70 transmembrane 69 vimentin 69 CaM 69 COOH terminal 69 F actin 69 GTPase 69 EGFP 69 transactivation 69 cytoplasmic domain 69 membrane protein 69 nucleolar 69 Supplementary Fig 69 Fig. 1C 68 endocytic 68 ATPase 68 Rap1 68 GAPDH 68 plasma membrane 68 endonuclease 68 autophagic 68 γ 68 apical membrane 68 EBNA1 68 vacuolar 68 retinoic acid receptor 68 iNOS 68 VE cadherin 68 catenin 67 synthase 67 proteolytic cleavage 67 basolateral 67 dimeric 67 carboxyl terminal 67 constitutively active 67 perivascular 67 endoplasmic reticulum 67 phosphatidylinositol 67 immunoreactivity 67 NFAT 67 Vps# 67 E cadherin 67 disulfide bond 67 epithelia 67 rRNA 67 homodimers 67 ribonucleoprotein 67 isoforms 67 phosphorylates 67 phosphorylated 67 mRNA expression 67 β catenin 67 plastid 67 mitogen activated protein kinase 66 ATP hydrolysis 66 tyrosine phosphorylation 66 coexpression 66 erythroid 66 beta subunit 66 uPAR 66 importin 66 caveolin 1 66 transmembrane domains 66 RhoA 66 secretory 66 transduced 66 transmembrane protein 66 cells transfected 66 cytosol 66 transferase 66 Phosphorylation 66 actin cytoskeleton 66 CD1d 66 cofilin 66 Fig. 3a 66 Ca2 + 66 DNMT1 66 transcriptional repressor 66 endosomal 66 TGF ß 66 isoform 66 genes encoding 66 polypeptide 66 FGF signaling 66 extracellular 66 Rac1 66 TIMP 66 cytokeratin 65 laminin 65 cadherin 65 ERK1 65 acinar 65 subunit 65 homodimer 65 transfected 65 lysine residues 65 phosphoprotein 65 centromeres 65 lysosomal 65 phytochrome 65 receptor tyrosine kinase 65 ligand receptor 65 ectodomain 65 transferrin receptor 65 annexin V 65 fig. S1 65 mRNA 65 focal adhesions 65 enterocytes 65 downregulated 65 ciliated 65 immunoreactive 65 fibronectin 65 Cytoplasmic 65 colocalization 65 dephosphorylation 65 neurofilament 65 glucose transporter 65 GLUT4 65 centrosome 65 oligomeric 65 chemoattractant 65 exocytosis 65 morphogen 65 intron 65 ligand binding 65 H#K#me# 65 monocyte 65 PIP2 65 factor kappa B 65 Cdc# 65 lymphoid 65 adipocyte 65 TGF ß1 65 MT1 MMP 65 N cadherin 65 melanocyte 65 Smad3 65 cathepsin B 65 1beta 64 Fig. 2a 64 proximal tubule 64 epithelial cell 64 caveolae 64 Golgi 64 intramolecular 64 keratinocyte 64 heterodimers 64 Arp2 3 64 lamina 64 uracil 64 hTERT 64 SUMOylation 64 alveolar epithelial cells 64 heterochromatic 64 subcellular localization 64 splenocytes 64 glomerular 64 syntaxin 64 perinuclear 64 glycoprotein 64 immunostaining 64 STAT1 64 synthetase 64 Smad4 64 proto oncogene 64 proline rich 64 epithelial cells 64 ERBB2 64 Fig. 1B 64 amino terminal 64 luciferase reporter 64 clathrin 64 paxillin 64 apical 64 oligomerization 64 LIS1 64 intracellular 64 caspase activation 64 mitotic 64 PAK1 64 mononuclear 64 JNK1 64 phosphatase 64 histone H3 64 chromatin structure 64 Foxp3 64 dimerization 64 JAK STAT 64 CXCL# 64 erythrocytes 64 myofibroblasts 64 ligand 64 kinetochores 64 chloroplast 64 Nup# 64 cysteine protease 64 synaptic vesicles 64 regulated kinase ERK 64 alpha subunit 64 lysates 64 histone 64 actin polymerization 64 constitutively expressed 64 deacetylation 64 microglial 64 TGF beta1 64 aryl hydrocarbon receptor 64 ubiquitination 64 phospholipase 64 ribosomal 64 vascular endothelial cells 64 fig. S4 64 MyoD 64 E3 ligase 64 overexpressing 64 cyclin B1 64 postsynaptic 64 phagocytosis 64 murine 64 PIP3 64 carcinoembryonic antigen 64 tropomyosin 64 adherens junctions 64 epithelial 64 proteolysis 64 phosphorylation 64 mitochondrial 63 cell adhesion molecule 63 kinase domain 63 superfamily 63 cytochrome c 63 upregulation 63 leucine zipper 63 androgen receptor AR 63 cofactor 63 HIF 1alpha 63 H#K# [002] 63 chemotactic 63 focal adhesion 63 lipoxygenase 63 organelle 63 HepG2 cells 63 fascin 63 FasL 63 HOTAIR 63 c Src 63 Fig. 3b 63 thymocytes 63 lymphoid cells 63 breast epithelial cells 63 translationally 63 cell adhesion molecules 63 CCL# 63 calcium ion 63 FOXO 63 adhesion molecule 63 chromatin 63 dynein 63 methyltransferase 63 hnRNP 63 transgenic mice expressing 63 polycystin 63 LNCaP cells 63 ubiquitin ligase 63 transgene expression 63 CD#b 63 BMAL1 63 β1 63 astrocytic 63 actin binding 63 KLF4 63 subunits 63 phospho 63 Fig. 1D 63 activin 63 telomeric 63 Fig. 1a 63 Jhdm2a 63 coiled coil 63 ERK2 63 glycoproteins 63 diffusible 63 MEFs 63 stromal cells 63 receptor signaling 63 cyclin D1 63 actin filaments 63 tumor suppressor p# 63 aminopeptidase 63 transmembrane domain 63 metabolic enzymes 63 fig. S2 63 centromere 63 Oct4 63 6S RNA 63 guanosine 63 MAP kinase 63 histone modifications 63 membrane proximal 63 fig. S3 63 Fig. 1A 63 ATF2 63 transiently transfected 63 cyclin 63 occludin 63 mRNA encoding 63 wildtype 63 tubulin 63 H2AX 63 oncogenic transformation 63 Macrophage 63 proteins 63 neuroblastoma cells 63 Notch signaling 63 glycosyltransferase 63 COL#A# 63 FGFR3 63 IL 1ß 63 overexpression 63 myocytes 63 transfected cells 63 mRNAs 63 tetramer 63 serine protease 63 condensin 63 dimers 63 pRb 63 serine threonine kinase 63 receptor mediated endocytosis 63 substrate specificity 63 triacylglycerol 63 centrioles 63 Golgi apparatus 63 Htt 63 EF Tu 63 protein tyrosine phosphatase 63 3' 63 PC# cells 63 fibroblast cells 62 tau protein 62 NF κB 62 Smad 62 p# NTR 62 Fas ligand 62 Extracellular 62 lacZ 62 matrix metalloproteinases 62 ribonuclease 62 IL 1beta 62 proteolytic 62 sphingomyelin 62 ER alpha 62 β actin 62 coactivator 62 MEK1 62 biogenesis 62 reductase 62 histone H4 62 polypeptides 62 endosomes 62 caveolin 62 ERK signaling 62 phosphorylate 62 PrP 62 1alpha 62 ubiquitylation 62 anterior pituitary 62 Overexpression 62 integrins 62 alkaline phosphatase 62 cAMP 62 thymocyte 62 thioredoxin 62 HER2 receptor 62 matrix metalloproteinase 62 eukaryotic cell 62 heterochromatin 62 proteoglycan 62 null mice 62 SVZ 62 ERalpha 62 osteoblastic 62 PcG proteins 62 Ki# 62 histidine 62 Peroxisome proliferator activated 62 amino acid residues 62 receptor molecule 62 MyD# 62 H#K# [001] 62 chondrocyte 62 scavenger receptor 62 ubiquitinated 62 antibody antigen 62 IKKß 62 vacuole 62 apoptotic cells 62 beta amyloid peptide 62 intracellular signaling 62 receptor CD# 62 gene encoding 62 cohesin 62 TNFalpha 62 oncoprotein 62 homolog 62 IFN gamma 62 NS3 62 motoneurons 62 p#Kip# 62 apoptotic 62 TGF alpha 62 cell nuclei 62 transcription factor 62 Wnts 62 HER2 neu 62 osteogenic differentiation 62 Fig. 2b 62 lactate dehydrogenase 62 hypothalamic pituitary 62 transmembrane receptor 62 lyase 62 BMP signaling 62 IL 1β 62 tumor suppressor protein 62 Figure 1C 62 Oncogenic 62 cytoplasm 62 carboxy terminal 62 mononuclear cells 62 MnSOD 62 Purkinje cell 62 mesoderm 62 ribosomal DNA 62 ESCRT 62 PDGFR 62 neurite outgrowth 62 VSV G 62 polyadenylation 62 transcription factors 62 MAPK pathway 62 lamin 62 eNOS 62 serine threonine 62 junctional 62 cytoskeletal 62 microglial activation 62 kappaB 62 leukemic cell 62 fibroblast 62 CD# + [001] 62 receptor activator 62 NAD + 62 nucleoli 62 intestinal epithelial cells 62 Wnt signaling 62 chromosome condensation 62 protein fragment 62 secretory pathway 62 Rab# 62 SMAD4 62 acetylated 62 estrogen receptor alpha 62 LDL receptor 62 Leydig cells 62 TRPV4 62 P selectin 62 Caspase 62 eIF4E 62 erythrocyte 62 Cadherin 62 Peyer patches 62 adduct 62 Western blotting 62 RNA polymerases 62 ß1 62 TAp# 62 NFκB 62 Polycomb 62 osteoblast 62 MAPKs 62 hormone receptors 62 mitogen 62 evolutionarily conserved 62 Fig. 2C 61 tubule 61 Cre recombinase 61 GlcNAc 61 NKT cell 61 LRP6 61 synthases 61 transcriptional regulation 61 mice lacking 61 intestinal epithelium 61 epidermal cells 61 neuronal cell 61 phenotype 61 chemotaxis 61 tyrosine kinase receptor 61 beta actin 61 endothelial cell 61 61 mitochondrion 61 E3 ubiquitin ligase 61 Immunohistochemical analysis 61 oxidative phosphorylation 61 C#BL 6 mice 61 unmethylated 61 Upregulation 61 dynamin 61 phospholipid 61 TGF β 61 anaphase promoting complex 61 cystic fibrosis transmembrane conductance 61 vesicle fusion 61 STAT3 61 neuromuscular junction 61 metaphase 61 H#K# methylation 61 anaphase 61 homologous 61 beta globin 61 Ago2 61 cytochrome 61 4E BP1 61 heterodimer 61 forkhead 61 TGFb 61 cytokinesis 61 hepatocyte 61 protein 61 secretase 61 TIMP 1 61 PU.1 61 conformational changes 61 cell motility 61 IRE1 61 peroxisomes 61 ouabain 61 trimeric 61 FGF2 61 proapoptotic 61 RANTES 61 protein phosphatase 61 antigen binding 61 fig. S6 61 Aβ 61 monomeric 61 mannose 61 dimer 61 extracellular signal 61 epithelial cells lining 61 cyclic AMP cAMP 61 microsomal 61 mediated inhibition 61 disulfide bonds 61 Ser# 61 WNK1 61 meiotic 61 myosin 61 VEGFR1 61 transcriptionally 61 germinal center 61 mitochondrial membranes 61 gp# [002] 61 p# [001] 61 umbilical vein 61 posttranslational modification 61 kD 61 oxidase 61 membrane lipids 61 fluorescently tagged 61 induced apoptosis 61 nucleolin 61 ssDNA 61 1α 61 receptor proteins 61 pilus 61 EGF receptor 61 orthologs 61 T lymphocyte 61 PTPN# 61 hippocampal neurons 61 AMPA receptor 61 vesicle 61 c Myb 61 helicase 61 CD# CD# 61 plasminogen 61 esterase 61 alanine 61 chemokine receptor 61 mitotic spindles 61 GTPases 61 muscarinic receptors 61 histone acetylation 61 ectopic expression 61 At#g# 61 SNAREs 61 MDCK cells 61 miRNA expression 61 cysteine residues 61 #ß 61 semaphorin 61 catalytically active 61 beta catenin 61 hydroxylase 61 vesicular 61 p# mitogen activated 61 glycosylation 61 receptor 61 ribosomal protein 61 nucleolus 61 DNase 61 conformational 61 cellular organelles 61 c myc 61 bronchial epithelial cells 61 metalloprotease 61 myofibroblast 61 cytosine 61 Fig. 1d 61 estrogen receptor 61 Cx# [001] 61 EphB4 61 intronic 61 Fig. 2c 61 CagA 61 ncRNAs 61 adrenocortical 61 c Fos 61 upregulated 61 acyl CoA 61 translocates 61 NKX#.# 61 CPEB 61 plasmacytoid dendritic cells 61 virulence genes 61 isoleucine 61 HEK# cells 61 cadherins 61 effector 61 TNFR 61 GluR1 60 Mice deficient 60 stilbene 60 oligomer 60 nuclease 60 SGK1 60 immunodominant 60 Vpr 60 ligands 60 Sp1 60 aggrecan 60 secretory proteins 60 GLI1 60 phagocyte 60 mediated phosphorylation 60 HUVEC 60 tyrosine kinase 60 HtrA2 60 PKC isoforms 60 intercellular adhesion molecule 60 tubules 60 vascular endothelial 60 bone marrow stromal cells 60 intracellularly 60 Secretase 60 PPARg 60 Skeletal muscle 60 cytoplasmic tail 60 endoplasmic reticulum ER 60 Runx1 60 Nedd4 60 downregulation 60 mutant proteins 60 rhodopsin 60 hyperactivation 60 glycolipids 60 HSCs 60 malignant prostate 60 RNAs 60 dehydrogenase 60 mammary cells 60 palytoxin 60 interphase 60 mRNA transcripts 60 TORC2 60 paracellular 60 downregulate 60 Epithelial 60 HSP# 60 Fig. 3B 60 hexamer 60 phosphoinositide 60 endosome 60 keratinocytes 60 supernatants 60 centrosomes 60 cytochrome c oxidase 60 equimolar 60 P cadherin 60 Fig. 1E 60 Drp1 60 posttranslational modifications 60 osteocalcin 60 hyperactivated 60 dynactin 60 c Myc 60 trophoblast cells 60 MAPK 60 intercellular 60 receptor protein 60 somatostatin receptor 60 cytidine 60 Syt II 60 nitric oxide synthase 60 acetyl CoA 60 secretory cells 60 antiapoptotic 60 glycolipid 60 cytokine secretion 60 tyrosine hydroxylase 60 homologs 60 dsRNA 60 chromatid 60 regulating gene expression 60 transgene 60 triphosphate 60 p# MAPK 60 hexamers 60 #HT#A 60 guanine 60 TGFß 60 RNA polymerase II 60 metalloproteases 60 thymic 60 trophoblast 60 lymphocyte 60 Notch receptor 60 TACI 60 glioma cells 60 flavin 60 spindle fibers 60 Histone 60 cardiac myocytes 60 missense mutation 60 WT1 60 synaptogenesis 60 #BP# 60 intermediate filaments 60 microtubule 60 IFNg 60 IFN γ 60 KLF2 60 lung epithelial cells 60 actin filament 60 disulfide 60 adenylate cyclase 60 GPI anchored 60 thrombospondin 60 pyrimidine 60 pro inflammatory cytokine 60 adrenal cortex 60 flagellar 60 ploidy 60 mesenchymal cells 60 receptor gamma 60 Cathepsin B 60 nAChR 60 TGF b 60 clonogenic 60 p#NTR 60 polyamine 60 paracrine 60 SOD1 60 telomerase reverse transcriptase 60 ENaC 60 NADPH 60 kDa 60 Dpp 60 immunoblotting 60 peptidase 60 TGF β1 60 noncoding 60 metalloproteinase 60 ATPase activity 60 cytokine receptors 60 fatty acid synthesis 60 transcriptional regulator 60 cytoskeletal proteins 60 angiotensinogen 60 somatic cells 60 Fig. 3A 60 Fig. 4B 60 CD4 + T lymphocytes 60 synaptic vesicle 60 mitochondrial gene 60 granulocytes 60 T#M 60 Figure 1A 60 Schematic diagram 60 receptor kinase 60 ß amyloid 60 IKKa 60 ryanodine receptor 60 RNA binding 60 PDZ domain 60 hematopoietic progenitors 60 homologue 60 eukaryotic 60 Fig. 2A 60 Fig. 1c 60 desaturase 60 glycosylated 60 transduction 60 Fig. 60 endocytosis 60 IGFBP 60 hydrolase 60 dependent protein kinase 60 miR# 60 stromal 60 acyltransferase 60 hematopoiesis 60 galactosidase 60 potassium ion 60 mammary epithelial cells 60 lymphoid tissue 60 SDS PAGE 60 decarboxylase 60 bcl 2 60 3' UTR 60 fluorophore 60 pDC 60 striatal 60 adipogenic 60 cardiac fibroblasts 60 VEGF expression 60 SOCS3 60 MMP9 60 Nanog 60 survivin 60 PBMCs 60 focal adhesion kinase FAK 60 radial glia 60 protein kinase 60 regulates gene expression 60 N Myc 60 p# mutation 60 histologically 60 receptor gene 60 endothelial 60 NF kappaB 60 basolateral membrane 60 transporter proteins 60 Ku# 60 X inactivation 60 PP2A 60 lymphangiogenesis 60 GLUT1 60 Hedgehog signaling 60 globin gene 59 insulin signaling pathway 59 Rad# 59 Mcl 1 59 adipose cells 59 palmitate 59 dioxygenase 59 RAD# [001] 59 biotinylated 59 NKG2D 59 gut mucosa 59 myo inositol 59 adipogenesis 59 urothelial 59 mTOR signaling 59 fig. S# 59 RAS RAF MEK 59 proteinase 59 Notch1 59 mRNA translation 59 gastric mucosa 59 chromosomal rearrangement 59 opsin 59 Tubulin 59 Sox9 59 glyceraldehyde 3 59 chaperone proteins 59 FAK 59 integrin 59 induces apoptosis 59 ultrastructure 59 polymerases 59 signaling pathway 59 homologues 59 dehydrogenases 59 autocrine 59 enzymatic activity 59 mitotic spindle 59 MALAT1 59 transcriptionally active 59 phagosomes 59 glutamate receptor 59 Rho GTPases 59 P gp 59 RecA 59 c fos 59 3'UTR 59 thymidine 59 micronuclei 59 cis 59 hydrogenase 59 Th2 59 p# activation 59 valine 59 effector function 59 metallothionein 59 chromosomal DNA 59 titin 59 tetramers 59 transcriptional machinery 59 glutamyl 59 unmethylated DNA 59 Ubx 59 downregulates 59 budding yeast 59 A. thaliana 59 mitotic progression 59 fibrillar 59 serine 59 sister chromatid 59 CTCF 59 choroid plexus 59 endogenous 59 cell organelles 59 KaiC 59 pDCs 59 extracellular domain 59 lipid rafts 59 endocytic pathway 59 hematoxylin 59 homozygotes 59 kinase pathway 59 M1 muscarinic 59 neural crest 59 HIP1 59 phosphatidylinositol 3 59 leukocyte 59 protein kinase C 59 corpus luteum 59 membrane vesicles 59 α 59 adhesion molecules 59 dinucleotide 59 polymorphonuclear leukocytes 59 Rb#/p# 59 oligodendrocyte 59 TNF α 59 NOD SCID mice 59 somatostatin receptors 59 protein complexes 59 heme oxygenase 59 neural progenitor cells 59 K + ATPase 59 effector protein 59 microvilli 59 polyglutamine 59 FGFR1 59 fusion protein 59 tetragonal 59 piRNAs 59 pre mRNA splicing 59 SOX9 59 outer membrane 59 PGCs 59 #S rRNA 59 Sertoli cell 59 mitochondrial biogenesis 59 immunofluorescence microscopy 59 Aß 59 rostral 59 demethylase 59 alternatively spliced 59 midgut 59 fission yeast 59 MLL gene 59 cytokine signaling 59 DMT1 59 proinflammatory