downregulated

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(Click for frequent words.) 75 upregulated 75 transduced 75 constitutively active 74 mRNA expression 74 constitutively expressed 74 ERBB2 73 ERK1 2 73 phosphorylated 73 IL 1β 73 somatostatin 73 mitogen activated protein kinase 73 HepG2 cells 72 RhoA 72 isoenzyme 72 receptor tyrosine kinase 72 CXCL# 72 androgen receptor AR 72 STAT1 72 cell adhesion molecule 72 overexpressing 72 catenin 72 transactivation 72 IGFBP 71 IL 1beta 71 CagA 71 FGFR4 71 metalloproteinase 71 caveolin 1 71 transfected cells 71 deacetylation 71 constitutively 71 cytosolic 71 inducible nitric oxide synthase 71 TNFalpha 71 COL#A# 71 S#A# [002] 70 Kupffer cells 70 HIF 1alpha 70 IL 1ß 70 upregulates 70 proto oncogene 70 eNOS 70 c MYC 70 4E BP1 70 p# MAPK 70 PDGFR 70 CD#b 70 uPAR 70 CDK4 70 iNOS 70 CCR7 70 polyamine 70 IFN gamma 70 hypermethylated 70 astrocytic 70 DNMT1 70 nAChR 70 LNCaP cells 70 serine protease 70 ERalpha 70 IL #p# 70 TIMP 1 70 homodimers 70 TIMP 70 miR #a [001] 70 Notch1 70 MAP kinase 70 coexpression 70 caveolin 70 ENaC 70 phosphatidylinositol 70 activating mutations 70 Rab5 70 GSTP1 70 ectopic expression 70 mice lacking 70 protein kinase C 70 matrix metalloproteinases 70 PTPN# 70 MMP2 70 IFN γ 69 Supplementary Fig 69 lipoxygenase 69 transfected 69 SIRT2 69 MAPK 69 monocyte chemoattractant protein 69 c myc 69 ERK signaling 69 tyrosine phosphorylation 69 induces apoptosis 69 amino terminal 69 CCL# 69 phosphorylates 69 miR #b [001] 69 MT1 MMP 69 GLI1 69 upregulation 69 TNF α 69 cathepsins 69 transcriptional activation 69 autophagic 69 Immunohistochemical analysis 69 activin 69 immunoreactivity 69 glycosylated 69 ERK pathway 69 evolutionarily conserved 69 Foxp3 69 polyadenylation 69 mediated inhibition 69 TGF β 69 CaM 69 Rap1 69 chemokine receptor 69 dephosphorylation 69 Clusterin 69 RRM1 69 mRNA transcripts 69 prostaglandin E2 PGE2 69 RANTES 69 tyrosine hydroxylase 69 alpha subunit 69 VEGFR1 69 cytokine signaling 69 overexpressed 69 Kir#.# 69 adrenoceptor 69 hTERT 69 FLT3 69 CD#c 69 eotaxin 69 overexpressing cells 69 heterozygotes 69 ChR2 69 induced apoptosis 69 downregulation 68 phosphorylate 68 TNFa 68 matrix metalloproteinase 68 pDCs 68 secreted protein 68 LDL receptor 68 valine 68 c Src 68 Overexpression 68 estrogen receptor alpha 68 cAMP 68 regulated kinase ERK 68 downregulates 68 1alpha 68 autocrine 68 aminopeptidase 68 erythrocytes 68 null mice 68 potent inhibition 68 transgene expression 68 β catenin 68 E#F# 68 adenylate cyclase 68 Eg5 68 mutant p# 68 cyclin E 68 EGFP 68 homozygotes 68 WT1 68 BMP2 68 genes encoding 68 pyruvate kinase 68 homodimer 68 ubiquitination 68 LRP6 68 transcriptional repressor 68 serine threonine 68 TGF ß 68 cyclooxygenase 68 NKG2D 68 potently inhibited 68 AMACR 68 EGFR protein 68 proapoptotic 68 MAPK pathway 68 lactate dehydrogenase 68 HER2 neu 68 pro inflammatory cytokine 68 beta subunit 68 PHD2 68 Bcl XL 68 bcl 2 68 differentially regulated 68 ß catenin 68 TAp# 68 68 BCL2 68 GRP# 68 NFκB 68 hypermethylation 68 heme oxygenase 68 thioredoxin 68 FasL 68 isoleucine 68 decarboxylase 68 μg ml 68 phosphatases 68 cytokine receptor 68 DLC1 68 neurofilament 68 isoprostane 68 68 alveolar epithelial cells 68 monocyte chemotactic protein 68 dimerization 68 cytokeratin 68 serine threonine kinase 68 kDa protein 68 cyclins 68 leukemic cell 67 Fas ligand 67 vimentin 67 67 receptor CXCR4 67 EphB4 67 induce apoptosis 67 67 antiapoptotic 67 SOX9 67 transmembrane receptor 67 adipogenic 67 cyclooxygenase COX 67 PTHrP 67 wildtype 67 enzymatic activity 67 glomerular 67 BMP signaling 67 tumorigenicity 67 TTR gene 67 metabolizing enzyme 67 p# activation 67 5 lipoxygenase 67 PAX5 67 pDC 67 upregulating 67 TGF alpha 67 transiently transfected 67 protein tyrosine phosphatase 1B 67 MEK1 67 Interferon gamma 67 67 IGF1R 67 acyl CoA 67 TMEM#B 67 cysteine protease 67 μmol L 67 PIP2 67 glucocorticoid receptor 67 transferase 67 cytokine interleukin 67 kinase gene 67 PKC isoforms 67 ErbB4 67 H#K#me# 67 uM 67 CD# CD# 67 hepatoma 67 FOXO3a 67 5 hydroxytryptamine 67 IGF IR 67 HBx 67 isoforms 67 E selectin 67 IGFBP 3 67 dimeric 67 alkaline phosphatase 67 RAS RAF MEK 67 thyroid hormone receptor 67 P2X 67 Nampt 67 osteoblast 67 splice variants 67 EGFRvIII 67 CCR9 67 receptor mediated endocytosis 67 overexpress 67 histone H3 67 PKC beta 67 phosphatase 67 phosphoprotein 67 K + ATPase 67 Pten 67 heterodimers 67 MDR1 67 IL #R 67 VEGF receptor 67 ErbB receptors 67 67 steroidogenic 67 deficient mice 67 P selectin 67 protein tyrosine kinase 67 cyclin dependent kinase inhibitor 67 Hypoxia Inducible Factor 67 BMAL1 67 #β estradiol 67 lysosomal 67 ERa 67 promoter methylation 67 V#F mutation 67 cytokines IL 67 subcellular localization 67 beta actin 67 tryptase 67 prolyl 67 monocyte 67 extracellular signal 67 protein tyrosine phosphatase 67 missense mutations 67 phospho 67 hepatic lipase 67 IgG1 67 cathepsin B 67 Src kinase 67 GlcNAc 67 hematopoietic progenitors 67 Leydig cells 67 terminally differentiated 67 VE cadherin 67 mitogenic 67 LPS induced 67 cofactor 67 cyclin D1 67 Ki# 67 hydrolases 67 RUNX3 67 GLUT4 67 p# p# 67 Skp2 66 cystic fibrosis transmembrane conductance 66 TGF b 66 Dysregulation 66 Vps# 66 μM 66 carboxyl terminal 66 Ca2 + 66 nM 66 1beta 66 p#Kip# 66 FGF2 66 transmembrane protein 66 FGFR3 66 methyltransferase 66 p#NTR 66 c MET 66 leptin receptor 66 Smad3 66 TNFR 66 antiproliferative activity 66 ERK activation 66 ras gene 66 inducible 66 plasmacytoid dendritic cells 66 adduct 66 Th2 66 virulence genes 66 clusterin 66 paxillin 66 PGE2 66 IFN alpha 66 selectively binds 66 IFNg 66 erythroid 66 anti apoptotic 66 oncogenic 66 ubiquitinated 66 succinate dehydrogenase 66 NKCC1 66 adrenergic receptors 66 miR# 66 AMPA receptor 66 PAK1 66 melanocyte 66 NO synthase 66 #HT#A 66 GLUT1 66 CYP# [002] 66 nucleolin 66 PPARg 66 GNAQ 66 microglial activation 66 MLH1 66 proteolytic cleavage 66 HER2/neu 66 isotypes 66 isoform 66 proinflammatory cytokines 66 selectively inhibited 66 anti inflammatory cytokine 66 HIF 1a 66 cyclin B1 66 lacZ 66 intercellular adhesion molecule 66 XL# inhibits 66 Hsp# [001] 66 COX2 66 ribosomal protein 66 AhR 66 CEACAM1 66 Sp1 66 MyoD 66 TRPV4 66 mediated apoptosis 66 caspase activation 66 hydroxylase 66 vascular endothelial cells 66 papillary RCC 66 synthase 66 SOCS3 66 cytokine IL 66 cytoplasmic domain 66 urocortin 66 HDAC2 66 C#BL 6 mice 66 NKX#.# 66 ganglioside 66 adhesion molecule 66 Th1 66 KIT mutations 66 Phosphorylation 66 intronic 66 histone H4 66 IGF binding 66 p# mutation 66 erythrocyte 66 proteolysis 66 Akt signaling 66 secretory 66 thyrotropin 66 mineralocorticoid receptor 66 5alpha reductase 66 TGFb 66 CaMKII 66 phosphoinositide 66 interleukin IL -6 66 interferon IFN 66 neoplastic cells 66 colon carcinoma 66 β 66 TNFα 66 Jhdm2a 66 STAT5 66 splenocytes 66 beta1 integrin 66 interleukins 66 hypoxia inducible factor 66 lysyl oxidase 66 PKC inhibitor 66 selective modulator 66 mTOR signaling 66 Cx# [001] 66 carcinoembryonic antigen 66 acetylated 66 motoneurons 66 CYP#B# 66 potent inducer 66 phosphatidylinositol 3 66 tropomyosin 66 aberrantly activated 66 transcriptional regulation 66 serotonin receptor 66 LRAT 66 TCF#L# 66 stably transfected 66 CYP#A# [002] 66 reductase 66 Rho GTPases 66 receptor kinase 66 c KIT 66 E3 ligase 66 GHRH 66 endothelial nitric oxide synthase 66 muscarinic 66 HepG2 66 secretory pathway 66 FGFR1 66 Cathepsin B 66 C. albicans 65 MDM2 65 immunoreactive 65 basolateral 65 acetyl CoA 65 nutlin 3a 65 PTP1B 65 induced phosphorylation 65 overexpression 65 Akt 65 Î ² 65 SMAD4 65 TrkB 65 Macrophage 65 CD8 + 65 chemoattractant 65 unmutated 65 inhibited tumor 65 autoantibody 65 GAPDH 65 TRAIL induced apoptosis 65 pRb 65 neurite outgrowth 65 PI3 kinase 65 alternatively spliced 65 EGFr 65 protein encoded 65 MMP9 65 SNP rs# [002] 65 tumor suppressor protein 65 Drosha 65 glycolytic 65 SCD1 65 microglial 65 effector memory 65 KRAS oncogene 65 hypothalamic pituitary 65 cyclin dependent kinase 65 CTGF 65 coactivator 65 MSH2 65 TGF beta1 65 constitutive activation 65 alpha2 65 ABCA1 65 KLF4 65 Dpp 65 cyclic AMP cAMP 65 H#K# [002] 65 fig. S1 65 ErbB 65 osteocalcin 65 enterocytes 65 cisplatin resistant 65 oncogenic transformation 65 hCG Beta 65 mitochondrial respiration 65 acinar 65 neuronal differentiation 65 p# mitogen activated 65 MUC1 65 receptor gamma 65 JAK STAT 65 kinase pathway 65 regulated kinase 65 HLA DR4 immune 65 proximal tubule 65 EphA2 65 NFkB 65 rRNA 65 HER2 HER2 65 TGF ß1 65 Th1 cells 65 tyrosine kinase 65 osteoprotegerin 65 unmethylated 65 myo inositol 65 colocalization 65 RASSF1A 65 transmembrane domains 65 MEFs 65 tyrosine kinases 65 matrix metalloproteinases MMPs 65 c Fos 65 VSV G 65 receptor inhibitor 65 ABCB1 65 lymphoid cells 65 oligomerization 65 cytoplasmic 65 T#M 65 nitric oxide synthase 65 GSTT1 65 anterior pituitary 65 circadian clock genes 65 GTPase 65 protein secreted 65 lactate dehydrogenase LDH 65 syngeneic 65 cyclooxygenase 2 65 E cadherin expression 65 steroidogenesis 65 synaptogenesis 65 MTHFR 65 transcriptional regulator 65 thrombospondin 65 fibroblast 65 neuroblastoma cells 65 miRNA genes 65 pro apoptotic 65 downregulate 65 IRE1 65 erythropoiesis 65 ribosomal proteins 65 FGF receptor 65 sequence homology 65 thrombin receptor 65 myeloid derived 65 PBMCs 65 pro angiogenic 65 peroxisomal 65 β cells 65 RAR beta 65 TGF β1 65 oxidase 65 cellular prion protein 65 thymosin 65 anaphase promoting complex 65 ERK1 65 cyclin dependent kinases CDKs 65 LNCaP 65 sphingolipid 65 phosphate dehydrogenase 65 LRP5 65 actin binding 65 SUMOylation 65 intron 65 Mcl 1 65 downregulating 65 chemokine 65 JNK1 65 cytochrome 65 FUS1 65 Immunohistochemical staining 65 extracellular domain 65 K#R [002] 65 redox active 65 inhibitory receptor 65 CD1d 65 acyltransferase 65 P cadherin 65 mutated p# 65 VIPR2 65 inflammatory cytokines 65 IFN g 65 DRG neurons 65 Htt 65 claudin 65 insulin receptors 65 ErbB2 65 Mice lacking 65 factor HGF 65 immunostaining 65 HDAC6 65 myocytes 65 SGLT2 65 MAPKs 65 PI3K Akt 65 constitutively activated 65 peptide receptor 65 substrate specificity 65 H#K# methylation 65 cofilin 65 intestinal epithelial cells 65 cell adhesion molecules 65 Akt1 65 casein kinase 65 retinoic acid receptor 65 stably expressing 65 neuronal dysfunction 65 MMP# 65 oligomeric 65 potent inhibitors 65 epithelia 65 hydrolase 65 thymic 65 cells transfected 65 Flt3 65 JAK2 enzyme 64 uPA 64 RNA polymerases 64 Jurkat cells 64 caveolae 64 MyD# 64 Th2 cells 64 N Myc 64 D aspartate 64 dioxygenase 64 granulocytes 64 IGFBP2 64 eIF4E 64 apoE 64 RKIP 64 PARP1 64 lytic 64 STAT3 64 calpain 64 Protein Kinase C 64 cotransporter 64 potent inhibitor 64 exocytosis 64 survivin 64 TOP2A gene 64 defensin 64 SMase 64 cyclic AMP 64 p# deficient 64 HIF 1α 64 VCAM 1 64 PLA2 64 IFN ß 64 dehydrogenase 64 Upregulation 64 tau phosphorylation 64 mRNA encoding 64 mRNA translation 64 acetylcholine receptor 64 pathophysiological effects 64 myocyte enhancer factor 64 E cadherin 64 cysteine residues 64 BACE1 64 glyceraldehyde 3 64 Wnt beta catenin 64 heme oxygenase 1 64 Cyclin E 64 Cdc# 64 Peyer patches 64 transiently 64 vWF 64 acetylation 64 cholecystokinin CCK 64 inverse agonist 64 monocytes macrophages 64 TRAF6 64 TrkA 64 RANK ligand 64 ß amyloid 64 Gly 64 alpha1 64 basophils 64 GSTM1 64 CD4 + CD# 64 Notch signaling 64 cAMP signaling 64 kDa 64 Rb#/p# 64 Rho GTPase 64 desaturase 64 FGFs 64 lyase 64 PIK3CA 64 thymocytes 64 lysine residues 64 c fos 64 mitogen activated protein kinases 64 CatB 64 synthetase 64 E3 ubiquitin ligase 64 GPI anchored 64 peroxidase 64 Cyclin D1 64 ubiquitin ligase 64 Tie2 64 hnRNP 64 UCP1 64 cells overexpressing 64 glycosylated proteins 64 syntaxin 64 NF kappaB activation 64 arginase 64 LKB1 64 VEGFR2 64 ubiquitylation 64 beta globin 64 aggrecan 64 Western blotting 64 Bcl 64 kinase domain 64 presynaptic 64 Notch receptor 64 receptor binding 64 receptor gene 64 Akt activation 64 isoenzymes 64 phosphate S1P 64 Bcl2 64 dehydroepiandrosterone sulfate 64 muscarinic receptors 64 C#Y 64 metalloprotease 64 ouabain 64 PDE#A 64 PON1 64 Monocyte 64 FANCD2 64 metaphase 64 CXCR2 64 hepatocellular carcinomas 64 mevalonate 64 receptors EGFR 64 β1 64 HER2 amplification 64 AT1R 64 BRAF V#E 64 ^ sup + 64 paracrine 64 PEDF 64 coding genes 64 GFAP 64 FGF signaling 64 thymocyte 64 N methyl 64 inhibitory effect 64 mineralocorticoid 64 vacuolar 64 apoA 64 VEGFR 64 Fig. 1A 64 PTP 1B 64 MDA MB 64 IKKß 64 SETDB1 64 tumorigenic 64 epithelial cells lining 64 clonogenic 64 inflammatory cytokine 64 MnSOD 64 proteinase 64 PGC 1α 64 Supplemental Figure 64 rs# [004] 64 vasodilatory 64 tumor antigen 64 nanomolar 64 PcG proteins 64 enolase 64 FGFR2 64 H#K# [001] 64 SMN1 64 miRNA expression 64 lymphangiogenesis 64 FGF# 64 cytokine secretion 64 sFlt 1 64 ACh 64 activated macrophages 64 PDGFR alpha 64 FOXO 64 prostaglandin synthesis 64 ZNF# 64 alkaline phosphatase ALP 64 histone acetylation 64 prostate epithelial cells 64 γ 64 F actin 64 interferon pathway 64 endogenous 64 cytidine 64 TOP2A 64 EGFR receptor 64 aldose reductase 64 ATPase 64 β amyloid 64 TERT 64 CD# + [001] 64 bile acid 64 phagocytosis 64 pituitary hormones 64 S. cerevisiae 64 Tubulin 64 NFkappaB 64 beta catenin 64 microtubule associated 64 Fig. 1B 64 TET2 64 POMC neurons 64 histone deacetylases 64 palladin 64 hENT1 64 glucose transporter 64 matrix metalloproteases 64 Fig. 1C 64 FKBP# 64 neuronal apoptosis 64 lymphoid 64 transmembrane 64 regulates gene expression 64 xenograft tumors 64 BMP4 64 prostate carcinoma 64 transthyretin 64 CCL2 64 lymphocytic 64 phospholipase 64 γ secretase 64 μ opioid receptor 64 trophoblast cells 64 intestinal epithelium 64 GluR1 64 midgut 64 kinase enzyme 64 actinin 64 cytolytic 64 paralogs 64 mice overexpressing 64 PAR1 64 hyperactivation 64 lysates 64 secretase 64 colony stimulating factor 64 α 64 NFAT 64 transcriptionally 64 mitogen 64 nNOS 64 potent stimulator 64 glutamic acid decarboxylase 64 glioma cells 63 Abeta# 63 IL6 63 p# alpha [001] 63 ornithine decarboxylase 63 spermatogenesis 63 RANKL 63 proteolytic processing 63 Heterozygous 63 short hairpin RNA 63 osteopontin 63 microRNA molecule 63 isomerase 63 inhibin B 63 SPINK1 63 orthologs 63 keratinocyte 63 cAMP dependent 63 CXCL5 63 Oct4 63 proinflammatory 63 histone methyltransferase 63 intracellular 63 PKM2 63 heparanase 63 excitatory neurotransmitter glutamate 63 NOTCH1 63 Wnt signaling 63 NADPH oxidase 63 polycystin 63 endonuclease 63 proteins encoded 63 endocytic 63 DNA methyltransferases 63 allelic variants 63 lymph node metastasis 63 chitinase 63 costimulatory molecules 63 GATA3 63 prostaglandin E 63 pyrimidine 63 LTB4 63 MDCK cells 63 calcineurin 63 serine 63 SATB1 63 RAD# [001] 63 UCP2 63 mPGES 1 63 p#INK#a 63 db db mice 63 aromatase 63 NF kB pathway 63 EGF receptor 63 Her2/neu 63 inflammatory cytokines TNF 63 Raf MEK ERK 63 gene encodes 63 5 HT2A serotonin 63 BRAF protein 63 antisense inhibition 63 estrogen receptor beta 63 nucleolar 63 agonist induced 63 intracellular signaling 63 cyclin 63 Vpr 63 SCN5A 63 uncoupling protein 63 lymphocyte activation 63 HUVEC 63 peripheral blood mononuclear 63 methylenetetrahydrofolate reductase 63 oncoproteins 63 IL8 63 TGFβ 63 amyloid deposition 63 proteases 63 acetylcholinesterase 63 Activating mutations 63 primary cilia 63 mitochondrial biogenesis 63 ribonuclease 63 5 HT2C receptor 63 leukocyte adhesion 63 interleukin IL -# 63 overactivation

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