Related by context. All words. (Click for frequent words.) 70 genotoxicity 69 cytotoxicity 66 carcinogenicity 66 immunotoxicity 65 anticancer activity 64 tryptase 64 mutagenicity 64 antitumor 64 radioprotective 63 estrogenic 63 histone deacetylase inhibitor 63 reproductive toxicity 63 cytoprotective 63 chemopreventive 63 thrombin receptor 63 teratogenic 63 erythropoietic 63 ERK signaling 63 plasma pharmacokinetics 63 prostanoid 63 endocrine disrupting 63 detoxify harmful 63 tumorigenicity 63 Cyclin E 63 DNMT1 63 Cathepsin B 62 AhR 62 potent inhibitor 62 NS#/#A protease 62 mutagenic 62 partial agonists 62 IgG antibody 62 redox active 62 potent inhibitors 62 Leukotrienes 62 antitumoral 62 mitogenic 62 antineoplastic 62 mediated inhibition 62 radiolabeled 62 splice variants 62 physico chemical properties 62 antitumor effect 62 histone deacetylases 62 induce apoptosis 62 potent anticancer 62 CYP#B# 62 carbamate insecticides 62 phosphate S1P 62 anticarcinogenic 62 receptor inhibitor 62 immunomodulating 62 tumorigenic 61 biotransformation 61 lyase 61 PPARgamma 61 oestrogenic 61 SIRT2 61 BCL2 61 adipogenic 61 homodimers 61 estrogenic effects 61 #beta 61 pathophysiological effects 61 p# activation 61 highly selective inhibitor 61 elastase 61 antiproliferative effects 61 potent neuroprotective 61 favorable pharmacokinetic profile 61 toxicity 61 potent carcinogen 61 neuroprotective properties 61 mutagens 61 immune modulatory 61 xenobiotic 61 systemically administered 61 mitogen activated protein kinase 61 MetAP2 61 glycolipids 61 HCV protease 61 Clusterin 61 antiangiogenic activity 61 CCR2 61 diphosphate 61 teratogens 61 pleiotropic 61 chemoprotective 61 Upregulation 61 apoptosis inducing 61 mitochondrial toxicity 61 interferon IFN 61 proteinase 61 Ionizing radiation 61 peroxidase 61 pharmacokinetic interactions 61 biodistribution 61 microsomal 61 Benzo pyrene 61 heterodimers 61 forskolin 60 antiproliferative activity 60 quinone 60 pharmacologically active 60 FUS1 60 teratogenic effects 60 antitumour 60 endocrine disrupter 60 potent inducer 60 HAAH 60 CYP #A# 60 nanomolar 60 heparanase 60 renal toxicity 60 pro apoptotic 60 transcriptional regulation 60 retapamulin 60 alkylating agent 60 hepatotoxic 60 stably transfected 60 selective modulator 60 HER2 receptor 60 Immunohistochemical analysis 60 acetylcholinesterase 60 adrenoceptor 60 TRAIL induced apoptosis 60 sulindac 60 developmental neurotoxicity 60 pharmacodynamic properties 60 somatostatin 60 cyclin dependent kinase inhibitor 60 proapoptotic 60 Lyn kinase 60 N methyl 60 topoisomerase II 60 polyamines 60 benzimidazole 60 selective inhibition 60 phosphatidylinositol 3 60 Cytochrome P# 60 fluorogenic 60 pRb 60 LRP5 60 immunotoxin 60 cardiotoxic 60 SERMs 60 antiproliferative 60 JAK2 enzyme 60 cytochrome P# 60 FGFR2 60 sGC 60 p# MAPK 60 Cotinine 60 transgene expression 60 cytopathic 60 cytotoxic 60 antiapoptotic 60 neurotoxicity 59 potent inhibition 59 immunomodulatory effects 59 spermidine 59 dermatophytes 59 HMG CoA reductase inhibitors 59 effector function 59 Aurora kinase 59 hypermethylated 59 oncogenic 59 assay detects 59 chemosensitivity 59 ecotoxicological 59 culture supernatants 59 alkylating 59 induced apoptosis 59 CB2 receptor 59 vasodilatory 59 EGFR tyrosine kinase inhibitors 59 deacetylation 59 IL #p# 59 promoter methylation 59 breast carcinogenesis 59 immune modulating 59 nephrotoxic 59 butyrylcholinesterase 59 glutathione peroxidase 59 chemopreventive agent 59 prolyl 59 3 carbinol 59 CDK inhibitor 59 cytotoxic effects 59 DFMO 59 selectively inhibited 59 inhibitory effects 59 inverse agonist 59 interleukin IL -# 59 micronuclei 59 naturally occurring amino acid 59 histone acetylation 59 glucocorticoid receptor 59 4E BP1 59 Darinaparsin 59 bronchodilatory 59 B. cepacia 59 HIF 1α 59 photoprotective 59 HepG2 cells 59 H#K# [001] 59 anti androgenic 59 cytostatic 59 IL 1β 59 pyrophosphate 59 preclinically 59 replicon 59 pharmacodynamic markers 59 equimolar 59 MGd 59 anti amnesic 59 antifibrotic 59 endotoxins 59 anti proliferative 59 T#M 59 FGFs 59 insulin sensitizing 59 p#Kip# 59 monomeric 59 ERalpha 59 oxysterols 59 Raf MEK ERK 59 L cysteine 59 antitumor effects 59 potent antiproliferative 59 hydroperoxide 59 excitotoxic 59 poly ADP ribose polymerase 59 hydrolase 59 flavopiridol 59 beta actin 59 phototoxicity 59 acrolein 59 NKX#.# 59 oligomeric 59 Sulforaphane 59 plasma lipid 59 endothelial nitric oxide 59 cardioprotective effects 59 PCV1 59 E#F# 59 inflammasome 58 HBx 58 TPMT 58 androgen receptor AR 58 WNK1 58 MTHFR 58 immunomodulation 58 apoptosis induced 58 hydrolases 58 K ras mutations 58 NF kappaB activation 58 peroxisome proliferator activated 58 mimics estrogen 58 pharmacodynamic PD 58 potent antitumor 58 E. faecalis 58 inhibit angiogenesis 58 ABCB1 58 somatostatin receptor 58 triacylglycerols 58 regulated kinase ERK 58 non nucleoside 58 CDDO Im 58 cyclic adenosine monophosphate cAMP 58 prostaglandin E2 PGE2 58 PPARγ 58 immune stimulatory 58 immunomodulatory properties 58 nicotinamide 58 anti atherogenic 58 Akt activation 58 glycosylated 58 c myc 58 FK# 58 naturally occurring molecule 58 neurotrophic 58 essential amino acid 58 mertansine 58 inhibit tumor 58 oral prodrug 58 orally bioavailable 58 Superoxide 58 vitro cytotoxicity 58 environmental toxicants 58 Enterobacter 58 Cytotoxic 58 58 serum biomarkers 58 inhibitory effect 58 metabolizing enzymes 58 anti apoptotic 58 inhibits protein synthesis 58 silymarin 58 5 HT2A serotonin 58 act synergistically 58 protein tyrosine phosphatase 58 toxicological studies 58 beta. 58 PHD2 58 CD#c 58 synthases 58 TNFalpha 58 pertussis toxin 58 carcinogenic polycyclic aromatic hydrocarbons 58 carcinogenic 58 ubiquinone 58 HDACi 58 pharmacodynamic endpoints 58 Lp PLA 2 58 chlamydial 58 substrates inhibitors 58 sPLA2 58 immunomodulatory 58 NPD1 58 sensitizer 58 malondialdehyde 58 Elevated serum 58 substrate specificity 58 safety tolerability pharmacokinetic 58 potency selectivity 58 #,# DCB 58 antioxidative 58 hormone disruptor 58 myeloperoxidase 58 CCR9 58 antimetastatic 58 riociguat 58 antiangiogenic 58 calcitonin gene related 58 ginsenosides 58 antimitotic 58 methylated DNA 58 GSTP1 58 Reactive oxygen species 58 vimentin 58 diol 58 NMDA antagonists 58 Histone 58 oligomerization 58 carcinoembryonic antigen 58 #ß 58 subcellular localization 58 immunostimulatory 58 axonal degeneration 58 Valortim ® 58 oxidase 58 potently inhibit 58 acesulfame 58 enzyme inhibition 58 IgA antibodies 58 retinoid X 58 busulfan 58 carboxylic acids 58 druggable target 58 favorable pharmacokinetic 58 glutathione GSH 58 thromboxane A2 58 phosphorylate 58 adipogenesis 58 proteasome inhibitor 58 sulfated 58 amine oxidase 58 Metabolites 58 serine threonine 58 Drospirenone 58 virulence genes 58 Sphingomab 58 serum antibodies 58 immunoblot 58 lipopolysaccharide 58 estrone 58 novel anticancer 58 induces apoptosis 58 clinically meaningful differences 58 pyrimidines 58 ENMD # 58 NFkappaB 58 Pgp 58 Genetic variation 58 costimulation 57 PARP inhibition 57 antiandrogens 57 aminotransferase 57 dihydrofolate reductase 57 Nedd4 57 superoxide anion 57 heme oxygenase 57 sublethal 57 synthetic lethality 57 allergenic proteins 57 Pegylated 57 cyclase 57 ochratoxin 57 SIRT1 activators 57 potent stimulator 57 prenatal exposures 57 methylxanthines 57 TGF ß 57 airway responsiveness 57 serine protease 57 teratogen 57 ionizing irradiation 57 PDGFR 57 antiinflammatory 57 lysophosphatidic acid 57 peroxynitrite 57 PTPN# 57 flavanones 57 malate 57 endoxifen 57 PARP inhibitor 57 Cdc7 57 biologically inactive 57 RRM1 57 mucins 57 GAP #B# 57 phosphatases 57 resistin 57 polybrominated 57 outer membrane proteins 57 thiourea 57 enzyme cofactor 57 hormonally active 57 endogenous ligands 57 xenobiotics 57 anti neoplastic 57 acetylated 57 γ secretase 57 cell lysis 57 defensin mimetic antibiotic 57 Phytoestrogens 57 methylate 57 topoisomerase II inhibitor 57 mineralocorticoid 57 aryl hydrocarbon receptor 57 asparaginase 57 sensitizers 57 TGF alpha 57 transferase 57 immunostimulatory effects 57 cMET 57 isoenzyme 57 endocrine disruptor 57 immunotoxins 57 potent cytotoxic 57 IL #E 57 Posiphen 57 immune suppressive 57 BaP 57 metabolites 57 GRP# 57 kinase inhibition 57 histone deacetylase HDAC 57 histone acetyltransferase 57 bile acid 57 arabinose 57 gliadin 57 oxidant stress 57 estrogen receptor beta 57 muscarinic 57 Hh pathway 57 allergenicity 57 p# alpha [001] 57 propyl 57 GPx 57 E selectin 57 orally dosed 57 endoglin 57 constitutively expressed 57 PI3 kinase inhibitors 57 microtubule targeting 57 thrombogenic 57 HCV replicon 57 receptor agonists 57 5alpha reductase 57 bacterial endotoxin 57 #ME# 57 hydrolyzing 57 GABAB receptors 57 oncoproteins 57 OGG1 57 V#F mutation 57 ENaC 57 upregulate 57 myo inositol 57 DNA methyltransferases 57 furan 57 β carotene 57 JAK#/JAK# 57 Soy isoflavones 57 preclinical efficacy 57 upregulation 57 thyrotropin 57 NNK 57 BChE 57 ergot alkaloids 57 alpha glucosidase 57 butylated 57 albumin bound paclitaxel 57 adducts 57 Butyrate 57 mitochondrial metabolism 57 lymphotoxin 57 #beta HSD1 57 degranulation 57 selective kinase inhibitor 57 cytochrome P# #A# 57 vascular disrupting 57 beta subunit 57 antitumor activity 57 murine models 57 Hsp# [001] 57 adenosine diphosphate ADP 57 Aurora Kinase 57 5 HT1A receptor 57 lung epithelial cells 57 REP# 57 leukotriene 57 HCV replication 57 CYT# potent vascular disrupting 57 xanthine 57 miRNA expression 57 matrix metalloproteinases MMPs 57 Onconase 57 IL 1ß 57 intracellular uptake 57 Valortim R 57 immunoreactivity 57 peroxidation 57 aspartate 57 HCV protease inhibitors 57 Th1 type 57 demonstrated antitumor activity 57 phosphorylates 57 anti fibrotic 57 SIRT3 57 thymidylate synthase 57 benzothiazole 57 pyridoxal 57 ISTODAX 57 follicle stimulating hormone FSH 57 anti leukemic 57 daidzein 57 isotypes 57 aberrantly activated 57 VE cadherin 57 potent inhibitory 57 mRNA expression 57 IL6 57 glucagon receptor 57 receptor gamma 57 colorectal tumors 57 fosbretabulin 57 5 HT1A 57 enzyme inhibitor 57 bleomycin 57 sarcosine 56 Oxidative 56 phenolphthalein 56 Immunohistochemical 56 hydrolytic 56 tubulin binding 56 mTOR inhibitors 56 oxidases 56 dose dependently 56 RNAi mediated 56 synthetic analogues 56 prostaglandin synthesis 56 miRNA expression profiles 56 Tyrima 56 cell adhesion molecule 56 arsenic trioxide ATO 56 lipid soluble 56 tubulin polymerization 56 dimeric 56 kappa B 56 nephrotoxicity 56 evolutionarily conserved 56 methyltransferases 56 CDK4 56 GLP 1R 56 FGFR4 56 ACh 56 cyclooxygenase COX 56 inhibitory activity 56 immunological responses 56 ethyl mesilate 56 COX enzymes 56 neuropeptide Y NPY 56 lymphocyte proliferation 56 demethylase 56 dimethyl 56 prostaglandin E2 56 triphosphate 56 phosphonate 56 pDCs 56 ALV# 56 erlotinib Tarceva ® 56 cisplatin resistant 56 aminobutyric acid 56 β amyloid 56 PIK3CA 56 ERK activation 56 intracellular accumulation 56 lysosomal 56 triterpenoids 56 dehydrogenases 56 GLI1 56 bronchoalveolar lavage fluid 56 sirtuin enzymes 56 IAP inhibitor 56 basophils 56 inducible nitric oxide synthase 56 LJ# [002] 56 triphendiol 56 antiandrogen 56 zearalenone 56 cathepsins 56 Or#b 56 vinca alkaloid 56 PDE#A 56 Celecoxib 56 benzalkonium chloride 56 vitro studies 56 cytokine receptor 56 mechanistic insights 56 racemate 56 adenylate cyclase 56 ESR1 56 systemic toxicity 56 pharmacodynamic effects 56 HIF 1a 56 sulfonylhydrazine class 56 DNA adducts 56 tumor subtypes 56 autoantigens 56 super oxide dismutase 56 agonists antagonists 56 potentiator 56 C. difficile toxins 56 nucleoside analogues 56 Interferon alpha 56 mRNA transcripts 56 chemically modify 56 solithromycin 56 LPA1 receptor 56 antitumor efficacy 56 histone deacetylase HDAC inhibitor 56 trophoblast cells 56 nitric oxide synthase 56 antidiabetic 56 Preclinical studies 56 serum lipid 56 carcinogenesis 56 PI3K/mTOR 56 cytotoxin 56 superantigen 56 Nicotinamide 56 hypericin 56 TNFa 56 mecamylamine 56 converting enzyme 56 PKCi 56 defensin 56 selective adenosine 56 IGFBP2 56 inosine 56 oestrogens 56 Bifidobacterium infantis 56 oxidative enzymes 56 MMP7 56 induced oxidative stress 56 epigenetic silencing 56 carbonyls 56 Amphinex ® 56 IKK2 56 receptor PPAR 56 ERK1 2 56 anti tumoral 56 CYP# [002] 56 IFNg 56 liposome encapsulated 56 p# mutations 56 HDAC2 56 antibiofilm 56 heptachlor 56 endothelin receptor antagonists 56 endothelial activation 56 catenin 56 indibulin 56 Ki# 56 Cry1Ab 56 iNOS 56 VIPR2 56 carboxylase 56 resistant mutants 56 β catenin 56 TMPRSS2 ERG 56 polybrominated diphenyl ethers PBDEs 56 phthalic acid 56 small molecule defensin 56 antioxidant enzyme 56 cleavable linker 56 ubiquitinated 56 Notch1 56 binding affinity 56 selectively inhibit 56 follicular adenoma 56 Vorinostat 56 diffusible 56 superoxide dismutase 56 polycyclic aromatic hydrocarbons PAH 56 SAR# [004] 56 phytoestrogen 56 TGF beta1 56 CYP#E# 56 glucoside 56 GSTT1 56 diethyl 56 tropomyosin 56 CYC# 56 antisense oligonucleotide 56 Kinoid 56 ABCA1 56 amifostine 56 protein tyrosine phosphatase 1B 56 MAGE A3 ASCI 56 ellagitannins 56 bioaccumulative 56 synthetase 56 Fas ligand 56 colon carcinoma 56 selenium supplementation 56 dimerization 56 MAPK pathway 56 luteolin 56 thiols 56 dephosphorylation 56 thioredoxin 56 pathogenetic 56 HQK 56 carbamates 56 hormone disruptors 56 valine 56 enteric bacteria 56 JAK inhibitors 56 Immunomodulatory 56 hERG 56 androgenic 56 Secretase 56 bortezomib Velcade 56 tiotropium bromide 56 magnesium stearate 56 MAPKs 56 nitrite nitrate 56 peripheral blood mononuclear 56 irritancy 56 metal cations 56 pro angiogenic 56 immunoglobulin G 56 peroxides 56 potent carcinogens 56 vivo potency 56 adrenocorticotropic hormone ACTH 56 paracrine 56 mtDNA mutations 56 microglial 56 genotoxic stress 56 IMiDs ® 56 vWF 56 airway hyperresponsiveness 56 IgG1 56 prostaglandin E1 56 DHFR 56 clioquinol 56 chromosomal rearrangement 56 clusterin 56 CCR1 56 ON #.Na 56 bexarotene 56 propionate 56 AMACR 56 conjugated estrogen 56 L alanine 56 viral kinetics 56 μg ml 56 carcinogenic mutagenic 56 selective inhibitor 56 drug metabolizing enzyme 55 nonsteroidal 55 pharmacodynamic 55 Toxicological 55 genotypic 55 PGC 1α 55 CYP#A# inhibitors 55 acute toxicity 55 adrenomedullin 55 alpha1 55 Sterols 55 HSF1 55 mGluR2 NAM 55 anti secretory 55 chimeric monoclonal antibody 55 prostaglandin E 55 autophagic 55 AAG geldanamycin analog 55 mGlu2 3 55 phagocytic cells 55 hormone disrupter 55 SMAD4 55 MUC1 55 neuroprotective effects 55 thyroid stimulating hormone 55 furanocoumarins 55 hypermethylation 55 cathepsin B 55 esterases 55 beta sitosterol 55 covalently linked 55 vascular disrupting agent 55 antiviral efficacy 55 neuro protective 55 histopathological 55 intestinal mucosal 55 phosphate binding 55 GLYX 55 hydroxyl radical 55 RASSF1A 55 estramustine 55 malondialdehyde MDA 55 downregulation 55 hydroxylase 55 enzymatic activity 55 thyroxine T4 55 IFN g 55 p# mutation 55 tyrosine phosphorylation 55 urinary concentrations 55 benzoates 55 Preclinical studies suggest 55 benzyl 55 Endotoxin 55 apolipoprotein B 55 acadesine 55 inhibiting COX 55 LRP6 55 teratogenicity 55 Schisandrin B 55 Flavanols 55 p# Shc 55 5' triphosphate 55 activate p# 55 investigational humanized monoclonal antibody 55 isoenzymes 55 unmeasured confounders 55 EGF receptor 55 Neuroprotective 55 neuroligins 55 TSLP 55 antiviral antibacterial 55 anti CD3 55 potent antibacterial 55 immunomodulator 55 BCR ABL mutations 55 MAP kinase 55 histone deacetylase 55 allelopathic 55 impair fertility 55 apigenin 55 florbetaben 55 activin 55 alkylating agents 55 selectively inhibits 55 heterocyclic amines 55 salinomycin 55 CRAC channel 55 pyrimidine 55 Hsp# inhibitors 55 Smad3 55 anticancer agent 55 hepatotoxicity 55 diamine 55 matrix metalloproteinases 55 enterolactone 55 p# antigen 55 VEGF receptor 55 neurotoxic 55 PEDF 55 potent antiviral 55 colorectal carcinogenesis 55 coactivators 55 solubilizing 55 thalidomide Thalomid 55 Corynebacterium 55 Kupffer cells 55 vivo 55 platelet adhesion 55 sphingolipid 55 gastrin 55 drug metabolizing enzymes 55 apoptotic pathway 55 Glucocorticoids 55 WT1 55 GAPDH 55 cyclic nucleotide 55 IgG4 55 toxicological 55 gamma aminobutyric acid 55 biochemical abnormalities 55 chemically reactive 55 S equol 55 Tß4 55 biologically active 55 haematopoietic 55 aflatoxin B1 55 malignant transformation 55 Valproic acid 55 osteoprotegerin 55 antisense inhibitor 55 telomere dysfunction 55 cultured mammalian cells 55 Anticalins ® 55 unconjugated 55 glycopeptide 55 immunohistochemical analysis 55 S/GSK# 55 proinflammatory 55 neurotoxic effects 55 phyto oestrogens 55 bone marrow suppression 55 non coding RNA 55 CD# expression [002] 55 sitosterol 55 murine model 55 LDL receptor 55 mevalonate 55 melanocyte stimulating hormone 55 potently inhibits 55 Dasatinib 55 phospho 55 etiologic 55 avidin 55 murine 55 Angiolix 55 lipoxygenase 55 sorafenib Nexavar 55 overactivated 55 kanamycin 55 Rap1 55 ALDH2 55 chemoresistance 55 antigenic proteins 55 biosynthetic pathways 55 Pim kinases 55 hesperidin 55 NF κB 55 PI3K Akt 55 GABAA receptors 55 eIF4E 55 hypoxia inducible factor 55 iodine uptake 55 Cloretazine R 55 cytolytic 55 RANTES 55 NFκB 55 carboxylic acid 55 flavones 55 thymidine 55 myopathy rhabdomyolysis 55 IgG antibodies 55 suppressor gene 55 glucuronide 55 hematopoietic cancers 55 c MYC 55 chromosomal instability 55 UsiRNAs 55 neuroinflammation 55 selective antagonist 55 AChE inhibitors 55 HMG CoA reductase 55 I3C 55 secretase 55 NQO1 55 neurite outgrowth 55 Organophosphate 55 thermal decomposition 55 gene polymorphisms 55 sulfonic acid 55 Immunohistochemical staining 55 antimicrobial peptide 55 TBBPA 55 metallothionein 55 Pathway Inhibitor