Related by context. All words. (Click for frequent words.) 70 genotoxic 68 mutagenicity 67 pharmacodynamic markers 66 immunotoxicity 65 tumorigenicity 65 plasma pharmacokinetics 65 STAT3 signaling 65 developmental neurotoxicity 65 anticancer activity 65 immunoblot 64 tryptase 64 chlamydial 64 pharmacodynamic properties 64 immunological responses 64 MetAP2 64 genotoxicity studies 63 Lp PLA 2 63 riociguat 63 bovine thrombin 63 Multimeric 63 QT QTc 63 preclinical efficacy 63 carcinogenicity 63 biochemical abnormalities 63 antitumor efficacy 63 cardioprotective effects 63 teratogenicity 63 redox active 63 pharmacodynamic PD 63 preclinically 63 favorable pharmacokinetic profile 63 cytotoxicity 63 cardiac repolarization 63 cytotoxic effects 63 histone deacetylase HDAC 62 chemosensitivity 62 HER2 expression 62 indibulin 62 antitumor effect 62 selenium supplementation 62 busulfan 62 MGd 62 pituitary hormone 62 reproductive toxicity 62 chemopreventive agent 62 induced oxidative stress 62 erythropoietic 62 immunohistochemical 62 transgenic rats 62 dose dependently 62 demonstrated antitumor activity 62 serum biomarkers 62 pharmacodynamic parameters 62 prion infection 62 phototoxicity 62 serum lipid 62 renal toxicity 62 potent inducer 62 pharmacokinetics PK 62 ADAMTS# 61 ELISpot 61 hERG 61 mediated inhibition 61 pulmonary toxicity 61 p# activation 61 systemically administered 61 epithelial barrier 61 Clusterin 61 flavopiridol 61 PCV1 61 physiologic mechanisms 61 NMDA antagonists 61 Darinaparsin 61 Onconase 61 prostanoid 61 metabolite concentrations 61 microdose 61 receptor inhibitor 61 Ophena 61 TPMT 61 vitro assay 61 tolerability pharmacokinetics 61 prenatal exposures 61 GRNCM1 61 murine model 61 p# MAPK 61 Azedra 61 pharmacokinetic equivalence 61 neurotoxicity 61 TLR antagonists 61 hepatotoxic 61 histone acetylation 61 systemic toxicity 61 serum antibody 61 allergenicity 61 vivo potency 61 5alpha reductase 61 ERK signaling 61 teratogenic effects 61 Valortim ® 61 pharmacokinetic pharmacodynamic 61 GPx 61 histone deacetylase inhibitor 61 pharmacokinetics pharmacodynamics 61 MAGE A3 ASCI 61 kallikrein 61 menadione 61 CYT# potent vascular disrupting 61 airway responsiveness 61 CYP #A# 61 HER2 overexpression 61 Pharmacodynamic 61 ovarian hormones 61 teratogenic 60 thyroid stimulating hormone 60 Aspergillus nidulans 60 iodine uptake 60 RRM1 60 steroidogenic 60 microglial 60 biodistribution 60 safety tolerability pharmacokinetic 60 endometrial hyperplasia 60 carcinoembryonic antigen 60 haematologic 60 GRP# 60 homocysteine concentrations 60 hematological parameters 60 aminotransferase 60 mertansine 60 CDK inhibitor 60 CCR9 60 Akt activation 60 prostaglandin synthesis 60 thalidomide Thalomid 60 mTOR inhibition 60 HDACi 60 EliA 60 adrenocorticotropic hormone ACTH 60 cMET 60 metabolomic profiling 60 ENMD # 60 alpha fetoprotein AFP 60 immunohistochemistry IHC 60 monoclonal anti 60 radiolabeled 60 impair fertility 60 Immunohistochemical staining 60 rBChE 60 neuroprotective effects 60 subchronic 60 RNAi mediated 60 neuroprotective properties 60 ABL1 60 Cytochrome P# 60 Western blotting 60 potent suppressor 60 ERalpha 60 immunopathology 60 neutrophil gelatinase associated lipocalin 60 Cotinine 60 immunomodulation 60 Fas ligand 60 acute toxicity 60 vitro dissolution 60 interferon IFN 60 interleukin IL -# 60 vidofludimus 60 rhITF 60 hepatic toxicity 60 activate p# 60 transgene expression 60 toxicological studies 60 thymidylate synthase TS 60 genotoxic stress 60 cyclooxygenase COX 60 potent cytotoxic 60 cell lysis 60 P2V TM 60 deacetylation 60 pharmacodynamic endpoints 60 Immunohistochemical analysis 59 chromosomal aberrations 59 Solorel TM 59 pharmacodynamic effects 59 procalcitonin 59 thorough QT 59 NF kappaB activation 59 AmpliChip 59 oxysterols 59 plasma kallikrein 59 CD# expression [002] 59 follicle stimulating hormone FSH 59 retapamulin 59 immune modulator 59 lactate dehydrogenase 59 PARP inhibition 59 androgen receptor AR 59 CBLC# 59 dose proportionality 59 platelet activation 59 malondialdehyde 59 Cardiotoxicity 59 oral prodrug 59 K ras mutations 59 serum cortisol 59 cytoprotective 59 immunohistochemical analysis 59 GSK3B 59 thromboxane A2 59 pharmacokinetic characteristics 59 sulindac 59 enzymatic pathways 59 MoxDuo ® IR 59 prostate carcinogenesis 59 sulodexide 59 selective inhibition 59 sonographic diagnosis 59 antitumour 59 AEG# 59 CG# [003] 59 elastase 59 solithromycin 59 environmental toxicants 59 Valortim R 59 PhG alpha 1 59 Flow cytometry 59 GLP toxicology studies 59 molecular biomarkers 59 Prodarsan ® 59 #beta 59 micronuclei 59 cisplatin resistant 59 axonal degeneration 59 Cardiorespiratory fitness 59 EGFR HER2 59 virulence genes 59 pleiotropic 59 HepG2 cells 59 effector function 59 heterologous expression 59 microRNA profiling 59 endoplasmic reticulum stress 59 PC# cells 59 spermidine 59 anti CD3 antibody 59 maternal serum 59 hepatic fibrosis 59 viral kinetics 59 mitochondrial toxicity 59 mutated K ras 59 antitumor 59 Trofex 59 plasma renin activity 59 culture supernatants 59 Genetic variation 59 PSMA ADC 59 Cyclin E 59 murine models 59 E selectin 59 retinoid X 59 OMP #M# 59 PTHrP 59 adrenal suppression 59 myeloperoxidase 59 selective modulator 59 physiologically relevant 59 humoral immunity 59 CDK4 59 Annexin V 59 pharmacokinetic PK 59 PI3 kinase inhibitors 59 Pharmacokinetic studies 59 PPARγ 59 erlotinib Tarceva ® 59 NF kB pathway 59 sitaxsentan 59 serum antibodies 59 ERK1 2 59 Xanafide 59 Amphinex ® 59 Drospirenone 59 enzyme inhibition 59 ELISPOT assay 59 Zoraxel 59 aminotransferase levels 59 antibody mediated 59 CCR5 antagonist 59 E. faecalis 59 thyroid stimulating hormone TSH 59 fetal malformations 59 humoral antibody 59 DNA demethylation 59 heparanase 59 isotypes 59 steroidogenesis 59 gastric adenocarcinoma 59 annexin 58 LRP5 58 excitotoxic 58 CD# expression [001] 58 Pharmacokinetic PK 58 etiologic 58 neuroregenerative 58 HIF 1a 58 Non inferiority 58 mimetics 58 APTIMA HPV 58 hypersensitivity allergic reactions 58 HCV replication 58 ON #.Na 58 acetylcysteine 58 thyrotropin 58 DFMO 58 Aviptadil 58 Androxal TM 58 inhibiting mTOR 58 sensitizer 58 orally dosed 58 non nucleoside 58 arachidonic acid AA 58 prostaglandin E1 58 genotypic resistance 58 GLYX 58 cardiotoxic 58 β blockers 58 Vidaza azacitidine 58 Soy isoflavones 58 soy isoflavone 58 motor neuron degeneration 58 vitro cytotoxicity 58 intact parathyroid hormone 58 immune dysregulation 58 immunofluorescent 58 Serological 58 Poly ICLC 58 UGT#A# 58 myopathy rhabdomyolysis 58 microglial activation 58 gene rearrangements 58 HCV protease inhibitors 58 VEGF expression 58 cardiac toxicity 58 bronchial lavage 58 fatty acid oxidation 58 SCD1 58 IL 1ß 58 intestinal mucosal 58 pharmacodynamic profile 58 compound AEZS 58 APOPTONE 58 enteric bacteria 58 radiosensitivity 58 optimal dosing 58 Posiphen 58 ERK5 58 antitumoral 58 toxicity 58 lymphocyte proliferation 58 pyrimidines 58 favorable pharmacokinetic 58 fibrotic disease 58 inhibitory effects 58 synthetic lethality 58 reproductive abnormalities 58 peroxidase 58 Th1 type 58 ALV# 58 β1 58 Ki# 58 pharmacokinetic PK profile 58 LT NS# 58 vitro experiments 58 salinomycin 58 amifostine 58 antiproliferative effects 58 autoimmune reactions 58 GPI anchored 58 Proellex TM 58 CTAP# Capsules 58 vivo efficacy 58 transcriptional regulation 58 replicon 58 DNMT1 58 mechanistic insights 58 bazedoxifene conjugated estrogens 58 neuronal differentiation 58 tumor hypoxia 58 Kinoid 58 growth hormone secretion 58 nephrotoxicity 58 imatinib therapy 58 preclinical pharmacokinetic 58 MTHFR 58 mitochondrial metabolism 58 immunohistochemical staining 58 plasmid encoding 58 DNA intercalator 58 cobiprostone 58 genetic polymorphism 58 Afatinib 58 biotransformation 58 substrate specificity 58 lactate dehydrogenase LDH 58 biologic plausibility 58 glucose homeostasis 58 #T# L1 58 metabolomic profiles 58 anti androgens 58 AST ALT 58 BioSilicon 58 metastatic neuroendocrine tumors 58 potent inhibitors 58 fluoroquinolone resistance 58 inducible nitric oxide synthase 58 inhibin B 58 EGFR signaling 58 pharmacokinetic interactions 58 vitro studies 58 mTOR inhibitors 58 LJ# [002] 58 immunoblotting 58 TNFalpha 58 ecotoxicological 58 alkaline phosphatase ALP 58 viral tropism 58 NQO1 58 inecalcitol 58 serum IgE 58 BRAF kinase 58 xenobiotic 58 acadesine 58 FISH fluorescence 58 HIF 1α 58 VA# [002] 58 PSN# [002] 58 human chorionic gonadotropin hCG 58 PDE#A 58 STRIDE PD 58 lipid oxidation 58 inhibitor rofecoxib 58 cyclophilin D 58 siRNA knockdown 58 Hh pathway 58 mda 7 58 DNA methyltransferases 58 microsomal 58 COPEGUS therapy 58 viral nucleic acids 58 squamous intraepithelial lesions 58 canakinumab 58 TNF α 58 natriuretic peptides 58 YONDELIS 58 biodistribution studies 58 acrolein 58 Six3 58 tumoral 58 immunostimulatory effects 58 liposomal amphotericin B 58 bFGF 58 CCR5 inhibitor 58 KRAS mutation status 58 lipoxygenase 58 mucosal immune responses 58 depsipeptide 58 bortezomib Velcade 58 corrected QT interval 58 5 HT2A serotonin 58 pharmacokinetic parameters 58 intracellular bacteria 58 CEACAM1 58 mycobacterial 58 nutlin 3a 58 Immunohistochemistry 58 colorectal adenoma 58 thyroxine T4 58 rhLF 58 cytological 58 trophoblast cells 57 qRT PCR 57 relapsed MM 57 reactogenicity 57 ALK inhibitors 57 thrombogenic 57 HIF 1alpha 57 LungAlert TM 57 Vidofludimus 57 uricase 57 edifoligide 57 homodimers 57 PENNVAX B 57 OGG1 57 endothelial activation 57 bevacizumab Avastin ® 57 bronchoalveolar lavage 57 HDAC inhibition 57 multiplex assay 57 experimentally induced 57 osteopontin OPN 57 p# antigen 57 neuro developmental disorders 57 chromosome aberrations 57 ELACYT 57 proteomic analysis 57 HER2 neu 57 SSc 57 masitinib 57 cardioprotection 57 anti CD3 57 plasma lipid 57 Chlamydia psittaci 57 cynomolgus monkeys 57 investigational humanized monoclonal antibody 57 prostate cancer CaP 57 LB# [003] 57 Tasigna prolongs 57 adrenocortical 57 CXCR7 57 serum concentrations 57 neurotrophic 57 bioequivalency 57 annexin V 57 enzymatic assay 57 histopathological 57 nonclinical studies 57 Zalypsis 57 PROCHYMAL 57 haematopoietic 57 Pharmacokinetics PK 57 antibody titer 57 CINTREDEKIN BESUDOTOX 57 #beta HSD1 57 CYP# [001] 57 vivo validation 57 skin sterol 57 NOD SCID mice 57 fosbretabulin 57 metabolic parameters 57 NKX#.# 57 PRT# 57 antigenicity 57 HGS ETR2 57 #F FDG PET 57 cardiac troponin 57 potency selectivity 57 MMP inhibitor 57 galiximab 57 glutamate signaling 57 malignant transformation 57 antitumor effects 57 sorafenib Nexavar 57 estrone 57 cisplatin gemcitabine 57 immunochemical 57 antiangiogenesis 57 REP# 57 adipogenic 57 Anticalins ® 57 neuron degeneration 57 FTIs 57 oestrogenic 57 sirtuin enzymes 57 NPC#L# 57 immune modulating 57 induces apoptosis 57 anti androgenic 57 bactericidal activity 57 IL #E 57 carcinogenesis 57 orally bioavailable mimics 57 hydroxy vitamin D 57 caspofungin 57 antiandrogens 57 glucocorticoid receptor 57 nucleotide substitutions 57 degranulation 57 d dimer 57 4E BP1 57 AGHD 57 alkylating agent 57 IgG1 57 miRNA expression 57 follicular fluid 57 TAT2 57 antiangiogenic agent 57 kinase inhibition 57 promoter methylation 57 hormone disruptor 57 coexpression 57 oocyte maturation 57 chemopreventive 57 recombinant erythropoietin 57 Jurkat cells 57 beta lactam antibiotic 57 somatostatin 57 FUS1 57 renoprotective 57 vascular disrupting agent 57 QTc prolongation 57 autophagic 57 serologic 57 Cathepsin B 57 apolipoproteins 57 organophosphorus compounds 57 hMG 57 CCX# 57 ABCB1 57 endogenous ligands 57 Tß4 57 endothelial nitric oxide 57 methacholine challenge 57 immunoglobulin G 57 parathyroid hormone PTH 57 IAP inhibitor 57 Leydig cell 57 teratogens 57 NFκB 57 quantitative PCR 57 cytologic 57 recurrent miscarriage 57 NFkappaB 57 nonvaccine 57 Aplidin 57 NPM1 mutation 57 receptor activator 57 IFN α 57 HGPIN 57 BSE prions 57 estrogen receptor beta 57 pDCs 57 immunostaining 57 antiviral efficacy 57 CD#c 57 colorectal adenocarcinoma 57 index assay IVDMIA 57 anterior pituitary 57 convergent validity 57 butyrylcholinesterase 57 chlamydial infection 57 Pegylated 57 #beta estradiol 57 HMG CoA reductase inhibitors 57 immunotoxins 57 intravenous bisphosphonates 57 antitumour activity 57 antiangiogenic agents 57 isoenzyme 57 Neisseria gonorrhoeae 57 ImmuKnow 57 iroxanadine 57 delipidation 57 cytokine receptor 57 MMP# 57 vimentin 57 MTT assay 57 #ß 57 viral titers 57 Nedd4 57 bronchoalveolar lavage fluid 57 Tyrima 57 VEGF receptor 57 cobalamin 57 antineoplastic 57 iPS derived 57 HepDirect prodrug 57 gastrointestinal absorption 57 resistant mutants 57 underlying molecular mechanisms 57 meta regression 57 kanamycin 57 Cry1Ab 57 intravenous dosing 57 PLX cells 57 Panzem 57 prucalopride 57 immunotoxin 57 erythropoiesis 57 midstage trials 57 airway hyperresponsiveness 57 D Dimer 57 peroxynitrite 57 NAGS deficiency 57 antiproliferative activity 57 LC#m# 57 peroxidation 57 prognostic significance 57 eprotirome 57 atherogenesis 57 HPA axis 57 chitinase 57 Dr. Bezprozvanny 57 radiolabeled TM# 57 prognostic markers 57 inosine 57 splice variants 57 TRO# 57 gastric mucosa 57 hemagglutination inhibition 57 TNFa 57 trastuzumab Herceptin ® 57 MORAb 57 alpha7 NNR 57 SIRT2 57 TriGrid ™ 57 glomerular filtration 57 multivariate Cox 57 exploratory endpoints 57 IntroductionThe 57 nitrates nitrites 57 bronchodilatory 57 epithelial tumors 57 LPS induced 57 8 OHdG 57 potent inhibition 57 Sym# 57 MGUS 57 mTOR kinase 57 PEDF 57 potent antitumor activity 57 Symadex 57 calcineurin inhibitors 57 novel VDA molecule 56 small molecule activators 56 thyroglobulin 56 phosphoprotein 56 inhibit angiogenesis 56 thiopurine 56 immunocytochemistry 56 telomerase activation 56 CoVal TM fusion 56 Enzastaurin 56 topoisomerase II inhibitor 56 capsular polysaccharide 56 antidepressant efficacy 56 #ME# 56 nucleoside analogues 56 myeloproliferative diseases 56 bronchial hyperresponsiveness 56 SNT MC# 56 Vaxfectin R adjuvant 56 potent stimulator 56 bacterial colonization 56 KRAS mutation 56 perfusion MRI 56 biochemical marker 56 nitrite nitrate 56 methylated DNA 56 anti androgen 56 Chlamydia pneumoniae 56 EGFR receptor 56 elevated homocysteine 56 nitrosothiols 56 IL6 56 postexposure 56 outer membrane proteins 56 retinal ischemia 56 ISTODAX 56 enterolactone 56 triphendiol 56 thymidylate synthase 56 macrophage infiltration 56 HCV replicon 56 anti amnesic 56 creatine kinase 56 Interferon alpha 56 irritancy 56 BAL# [002] 56 cell adhesion molecule 56 hematopoietic cancers 56 inflammatory biomarkers 56 bioscavenger 56 ischemia induced 56 osteogenic 56 coadministration 56 diagnostic biomarker 56 mucins 56 retaspimycin 56 NS#/#A protease 56 potent neuroprotective 56 Vaxfectin 56 ERCC1 56 metabonomics 56 thymosin beta 4 56 CaPre ™ 56 hepatotoxicity 56 IGF IR 56 adipocyte differentiation 56 S/GSK# 56 polysaccharide polymer 56 mecamylamine 56 isoprenoid 56 Butyrate 56 transgenic mice expressing 56 parthenolide 56 CLORETAZINE TM VNP#M 56 vivo experiments 56 WT1 56 mitogenic 56 lysophosphatidic acid 56 leukotriene pathway 56 nanocarrier 56 #I TM# 56 gamete formation 56 secretin 56 intranasal delivery 56 aberrant activation 56 vapreotide acetate 56 Cervista HPV 56 glycosylation pattern 56 vasodilatory 56 FOXP3 56 endocrine disrupting 56 IgG antibody 56 Prodarsan R 56 candidate DXL# CD# 56 parasitemia 56 prolonged QT interval 56 antibiofilm 56 semiquantitative 56 glomerular 56 inhibit viral replication 56 IFN γ 56 nicotinamide 56 chemoprotective 56 gadobutrol 56 GHRH 56 β carotene 56 endotoxemia 56 cytotoxic T lymphocyte 56 ionophore 56 sensitizers 56 FGFR3 56 5 Fluorouracil 56 Teriflunomide 56 delafloxacin 56 GAP #B# 56 β catenin 56 antiandrogen 56 potent anticancer 56 glycolytic 56 urine cytology 56 florbetaben 56 PSA nadir 56 inhibits protein synthesis 56 IL #p# 56 Endotoxin 56 ELISPOT 56 pan HDAC inhibitor 56 conjugated estrogen 56 biochemical markers 56 Creatinine 56 insertional mutagenesis 56 GW# [003] 56 XmAb# 56 bone marrow suppression 56 TMPRSS2 ERG 56 immunomodulatory effects 56 selective agonist 56 toxicologic 56 allergic airway inflammation 56 bevacizumab Avastin Genentech 56 anti fibrotic 56 NEUGENE antisense 56 serotonin synthesis 56 rtPA 56 CellCiphr 56 TLE3 56 acetylcholinesterase AChE 56 albumin bound paclitaxel 56 Cytotoxicity 56 sFlt 1 56 anti atherogenic 56 matrix metalloproteinases MMPs 56 potently inhibited 56 hepatoma 56 hematopoietic 56 fumagillin nanoparticles 56 radiation dosimetry 56 pleiotropic effects 56 pain palliation 56 eTag assays 56 antiangiogenic activity 56 MAPKs 56 fusion enhancers 56 posttranslational modification 56 IL 1β 56 Zysolin TM 56 transthyretin 56 PKC# 56 Haptoglobin 56 molecular diagnostic assay 56 DNA glycosylase 56 humoral immune responses 56 BMP2 56 SCH # 56 malignant polyps 56 inhibitor RG# 56 CETP inhibition 56 potentially hepatotoxic 56 hemostatic efficacy 56 intracellular uptake 56 ganciclovir 56 Dr. Sperandio 56 intravascular hemolysis 56 Cyclosporine 56 chemoprevention trials 56 ovarian carcinoma 56 prostaglandin E 56 serine protease 56 unmeasured confounders 56 Aclidinium 56 induced sputum 56 immunological 56 transdifferentiation 56 zearalenone 56 ionizing irradiation 56 ERK pathway 56 Antioxidant supplements 56 cannabinor 56 humanized monoclonal antibodies 56 F FDG PET 56 myo inositol 56 Dasatinib 56 therapeutic equivalence 56 PGC 1α 56 ultrastructural 56 murine 56 COPREXA ™ 56 teriflunomide 56 recombinant interferon 56 PET tracers 56 KRAS status 56 ATL# [001] 56 serine threonine 56 PCR assay 56 constitutively expressed 56 hydralazine 56 elotuzumab 56 SAR# [004] 56 prognostic indicator 56 highly immunogenic 56 CDDO Im 56 efaproxiral 56 E#F# 56 IFN g 56 SIRT3 56 estrogenic effects 56 cytochrome P 56 Cloretazine 56 eicosanoid 56 Tasimelteon 56 c MYC 56 PEGylated anti 56 xenograft models 56 analgesic efficacy 56 dihydrofolate reductase 56 monomeric 56 DHEA supplementation 56 soluble CD# 56 BrachySil 56 Meta analyzes 56 mammalian toxicity 56 inhaled TPI ASM8 56 immunologic 56 protein electrophoresis 56 N glycan 56 neointimal proliferation 56 Granulocyte Colony Stimulating Factor 56 Subgroup analyzes 56 FGFR4 56 ERa 56 FGFs 56 syngeneic 56 TLK# 56 Multivariate logistic regression 56 esterases 56 vivo pharmacology 56 orofacial clefts 56 herpesviruses 56 paricalcitol 56 EGFR TKI 56 transgenic mouse models 56 adult mesenchymal stem 56 56 electrophysiologic 56 urothelial cancer 56 CardioPET 56 osteogenic differentiation 56 enzymatic activity 56 Provecta TM 56 epoetin alpha 56 acetylcholinesterase 56 aurora kinase 56 ancrod 56 intestinal mucosa 56 endotoxins 56 CYP#B# 56 synthetic retinoid