Related by context. All words. (Click for frequent words.) 80 homozygous 75 homozygotes 74 heterozygotes 74 alleles 73 allele 71 C#Y 71 homozygosity 70 MLH1 69 genotype 69 mutant allele 69 phenotype 69 variant alleles 68 genotypes 68 germline mutations 68 MTHFR 68 missense mutations 68 homozygote 67 polymorphism 67 heterozygote 67 penetrance 67 K#N 67 Homozygous 67 GSTM1 67 rs# [001] 67 mosaicism 66 orthologs 66 rs# [004] 66 CC genotype 66 haplotypes 66 mutation 66 proband 66 null mice 66 haplotype 66 ABCB1 66 autosomal recessive 66 polymorphisms 65 MSH2 65 missense mutation 65 mutated gene 65 allele frequencies 65 COL#A# 65 rs# [002] 65 variant allele 65 Heterozygous 65 mice lacking 65 CDKN2A 65 rs# [003] 65 IL#B 65 wildtype 65 K#R [002] 65 PTPN# 65 UGT#A# * 65 PON1 65 CCR5 delta# 64 mutant alleles 64 GSTT1 64 immunoreactivity 64 transfected 64 mutations 64 C#BL/#J 64 CpG 64 apolipoprotein E 64 mutant gene 64 MnSOD 64 autosomal dominant 64 mRNA expression 64 APOE e4 64 unmethylated 64 normal karyotype 64 TT genotype 64 genotyped 64 germline mutation 64 diploid 63 maternally inherited 63 NF1 63 APOE4 63 genes encoding 63 overexpressing 63 heterozygosity 63 phenotypes 63 BRAF V#E 63 paternally inherited 63 LRAT 63 MC1R gene 63 A. thaliana 63 constitutively active 63 FMR1 63 V#F mutation 63 ApoE4 allele 63 syngeneic 63 apolipoprotein E gene 63 karyotypes 63 downregulated 63 genes predisposing 63 APOE ε4 63 ApoE4 63 APOE gene 63 EGFR mutations 63 UGT#B# 63 microsatellite instability 63 autosomal 63 APOC3 63 HFE gene 63 allelic variants 63 CAG repeats 63 KRAS mutations 63 OPRM1 gene 62 NNRTI resistance 62 DRD2 62 seronegative 62 selfing 62 CYP#C# * 62 IgA deficiency 62 HLA DRB1 * 62 ERBB2 62 frameshift mutation 62 allelic 62 breast carcinomas 62 karyotype 62 HLA B 62 noncarriers 62 #q# [001] 62 MYH9 gene 62 MHC genes 62 HLA DR 62 chromosome #q# [001] 62 phenotypically 62 dinucleotide 62 valine 62 ApoE gene 62 lymphocytic 62 deficient mice 62 ApoE 62 TP# mutation 62 dopamine transporter gene 62 microdeletion 62 methylenetetrahydrofolate reductase 62 gene polymorphism 62 thymic 62 K ras mutations 62 GSTP1 62 hepatocellular carcinomas 62 gene locus 62 sporadic ALS 62 FMR1 gene 62 CYP#C# [002] 62 transgene expression 62 chromosome #q# [002] 62 APOE allele 61 germline 61 CFH gene 61 autosomal recessive disease 61 promoter methylation 61 genetic variant 61 activating mutations 61 allele frequency 61 monozygotic 61 TP# mutations 61 immunocompetent 61 HepG2 cells 61 missense 61 familial ALS 61 Alu elements 61 cyclin E 61 intron 61 APOE4 gene 61 D. melanogaster 61 constitutively expressed 61 HBeAg positive 61 lymphocyte 61 VNTR 61 Leydig cell 61 #q#.# [001] 61 SHANK3 61 R#W [002] 61 receptor gene 61 CHD7 61 hypogonadotropic hypogonadism 61 HLA B# 61 Fig. 1C 61 thymocytes 61 CagA 61 virulence genes 61 C#BL 6 61 G allele 61 ApoE4 gene 61 KRAS gene 61 MLL gene 61 recessive gene 61 BALB c 61 intronic 61 RASSF1A 61 MTHFR gene 61 IFN gamma 61 GABRA2 61 TIMP 61 mutated K ras 61 premutation 61 PCa 61 microdeletions 61 immunoreactive 60 synuclein 60 genotypic 60 ε4 60 neoplasm 60 caveolin 60 dizygotic twins 60 FLT3 60 CD#c 60 hypermethylated 60 TMEM#B 60 BRCA1 BRCA2 60 MECP2 gene 60 BRCA2 mutation 60 EGFR gene 60 isoforms 60 C#BL 6 mice 60 EGFP 60 APOE e4 gene 60 haplogroups 60 PGCs 60 unmutated 60 #q# [002] 60 p# mutation 60 CNVs 60 KIF6 gene 60 prostate carcinoma 60 BDNF gene 60 ADH1B * 60 BRCA1 mutations 60 lymphoid cells 60 Th1 60 outbred 60 K ras gene 60 haplogroup 60 poorer prognosis 60 PDGFRA 60 inbred strains 60 dizygotic 60 HLA DQ2 60 CYP#D# 60 ribosomal protein 60 transfected cells 60 Immunohistochemical analysis 60 breast carcinoma 60 MAOA 60 rhesus 60 transmembrane protein 60 GISTs 60 xenograft tumors 60 pg ml 60 Leydig cells 60 loci 60 globin genes 60 MSH6 60 T2DM 60 monozygotic twins 60 #q#.# [002] 60 transgenic mice 60 cytokeratin 60 recessive genes 60 adenoma 60 decarboxylase 60 indels 60 apolipoprotein E4 60 subclinical 60 MetS 60 hereditary hemochromatosis 60 CD8 + 60 activating mutation 60 BRCA1 gene 60 dopamine receptor gene 60 orthologous 60 apoE4 60 ZNF# 59 gene variant 59 inherited mutations 59 euthyroid 59 CDH1 59 BALB c mice 59 immunofluorescence staining 59 erythrocytes 59 ploidy 59 mRNA transcripts 59 linkage disequilibrium 59 MDM2 59 trisomic 59 isoform 59 IKZF1 59 Nf2 59 upregulated 59 homologs 59 transcriptional repressor 59 paralogs 59 cell adhesion molecule 59 HbF 59 Wistar rats 59 aneuploid 59 HBV genotype 59 cytochrome b 59 Klinefelter syndrome 59 HNPCC 59 BMP2 59 MEFs 59 PALB2 59 5 HTTLPR 59 gene expression patterns 59 SNP rs# [001] 59 GFAP 59 HLA genes 59 atherosclerotic lesions 59 HCV genotype 59 Wwox 59 overexpressing cells 59 #p# [003] 59 chromosomal aberrations 59 APOE epsilon 4 59 enzymatic activity 59 SMN2 gene 59 pseudogenes 59 metaplasia 59 Fragile X gene 59 LPA gene 59 BRCA2 gene 59 Haplogroup 59 IGF2 59 parkinsonism 59 periventricular 59 gene mutations 59 Jhdm2a 59 mucinous 59 adenocarcinomas 59 del 5q 59 parasitaemia 59 FGFR2 59 cagA 59 seropositivity 59 apoE 59 isoprostane 59 c KIT 59 IDH2 59 isoleucine 59 isogenic 59 heritable traits 59 estrogen receptor ER 59 spontaneous mutation 59 MAOA gene 59 hTERT 59 coinfected 59 C. albicans 59 histologically 59 ribosomal proteins 59 isoenzymes 59 miR #a [001] 59 murine 59 interferon IFN 59 CYP#D# gene 59 IGFBP 59 isoenzyme 59 insertion deletion 59 proto oncogene 59 X inactivation 59 granulocyte 59 APOL1 59 transduced 59 hamartomas 59 TACI mutations 59 Foxp3 59 PTEN gene 59 Supplementary Fig 58 CYP#B# 58 subtype 58 multivariate Cox 58 #S rRNA 58 differentially expressed genes 58 defensin 58 phylogenetically 58 transferase 58 HBeAg negative 58 imprinted genes 58 nondemented 58 de novo mutations 58 herpesviruses 58 tyrosine phosphorylation 58 MC1R 58 fig. S1 58 cTnT 58 somatic mutations 58 VKORC1 58 TOP2A 58 μg ml 58 C1q 58 GSTM1 gene 58 HBsAg 58 hepatoma 58 SNPs 58 kDa protein 58 autoantibodies 58 MLL2 58 protein encoded 58 chromosomal rearrangements 58 pDC 58 lymph node metastasis 58 #p#.# [001] 58 HLA A2 58 Genotypes 58 Asymptomatic 58 granulocytes 58 EGFR mutation 58 single nucleotide polymorphism 58 vimentin 58 homologues 58 Bos taurus 58 monophyletic 58 chromosomal rearrangement 58 presenilin 58 atypical hyperplasia 58 SMN1 58 ortholog 58 immunostaining 58 monocyte chemotactic protein 58 VHL gene 58 BRCA2 carriers 58 microsatellite markers 58 FXTAS 58 cysteines 58 CYP#C# gene 58 germline cells 58 SLC#A# [002] 58 HLA DR4 immune 58 NRTI resistance 58 autosomes 58 alpha2 58 QTLs 58 mutant worms 58 haematopoietic 58 WT1 58 NPM1 mutations 58 M#V 58 CDK4 58 COMT gene 58 CFTR gene 58 cellular prion protein 58 serum concentrations 58 alpha1 58 gastric carcinogenesis 58 K ras 58 CYP# [002] 58 #p#.# [002] 58 APOE 58 probands 58 lamivudine resistant 58 rRNA 58 beta globin 58 deleterious mutations 58 amino acid substitutions 58 subcellular localization 58 lymphoid 58 pDCs 58 indel 58 P cadherin 58 leptin receptor 58 evolutionarily conserved 58 heritable 58 cytopathic 58 BRCA mutations 58 Clusterin 58 T#I [002] 58 YKL 58 inhibin 58 alveolar epithelial cells 58 nondiabetic 58 homologue 58 iNOS 58 chromosome #q#.# [001] 58 peripheral blood mononuclear 58 HGPIN 58 H#K#me# 58 TTR gene 58 fig. S2 58 gambiae 58 transgenic mice expressing 58 serine 58 gene polymorphisms 58 P. falciparum 58 recessive mutation 58 ciliated 58 haploid 58 HLA DRB1 SE 58 lobular 58 alternatively spliced 58 PDGFR 58 Fig. 1E 58 NF1 gene 58 immunoblotting 58 SRY gene 58 HIV uninfected 58 genetic polymorphism 58 clusterin 58 KLF4 58 monogenic 58 D#N 58 TCF#L# gene 58 ADPKD 58 BRAF mutation 58 Hashimoto thyroiditis 58 homodimer 58 V Leiden 58 gene variants 57 astrocytomas 57 nonsense mutation 57 gastric carcinoma 57 morphologic 57 CCR7 57 overexpressed 57 gene MECP2 57 Polymorphisms 57 LNCaP cells 57 IGF1 57 overexpress 57 X chromosome 57 exon 57 myostatin gene 57 BRCA mutation 57 TACI 57 neoplasms 57 CGG repeats 57 CHEK2 57 prostate cancer CaP 57 major histocompatibility complex 57 papillary renal cell carcinoma 57 C#T [001] 57 PTEN mutations 57 androgen receptor AR 57 gene mutation 57 BRCA1 mutation 57 MMSE score 57 genotypic resistance 57 2n = 57 androgen receptor gene 57 Nf1 57 Aß 57 basal cell nevus syndrome 57 cerebellar 57 clade B 57 DQB1 * 57 ALDH2 57 malignant transformation 57 ovarian carcinoma 57 GTPase 57 myeloid 57 CYP#C# [001] 57 morphologically 57 microcephalin 57 CD4 + CD# 57 E cadherin 57 mitochondrial DNA mtDNA 57 TCF#L# 57 BRAF V#E mutation 57 hypothalamic pituitary 57 miRNA expression 57 endostatin 57 alkaline phosphatase 57 DRD2 gene 57 TAp# 57 infarcts 57 potent inhibition 57 incomplete penetrance 57 transiently transfected 57 segmental duplications 57 Li Fraumeni syndrome 57 promoter polymorphism 57 SMAD4 57 IFN ß 57 constitutively 57 PrPSc 57 BMPR2 57 phosphorylate 57 alanine 57 KIT mutations 57 CD# + [001] 57 hydrolase 57 multivariate analyzes 57 HNSCC 57 functional polymorphism 57 ERCC1 57 Mice deficient 57 AMACR 57 IgG1 57 hyperplastic 57 mouse embryonic fibroblasts 57 recessive trait 57 BARD1 57 lysosomal 57 coexpression 57 overexpression 57 urothelial carcinoma 57 ESR1 57 chromosome #q 57 N acetyltransferase 57 TSC1 57 Histologic 57 MHC molecules 57 breast cancer genes BRCA1 57 substrate specificity 57 CEACAM1 57 inducible 57 leukemic cell 57 gene amplification 57 methylation patterns 57 ^ sup #m 57 polyploid 57 M. genitalium 57 TIMP 1 57 activin 57 PBMCs 57 APOA5 57 nonsense mutations 57 SNP rs# [002] 57 DRB1 * 57 pheochromocytomas 57 homolog 57 asymptomatic carriers 57 prepubertal 57 M#V mutation 57 globin 57 CIN3 57 ovariectomized 57 histological subtype 57 paragangliomas 57 FLT3 ITD 57 intergenic 57 Igf2 57 GBM tumors 57 ependymomas 57 tau gene 57 LPS induced 57 Apolipoprotein E 57 thyroglobulin 57 KRAS wild 57 survivin 57 brucei 57 Supplemental Figure 57 eotaxin 57 miRNA genes 57 synthases 57 lacZ 57 TOMM# 57 cells transfected 57 subfamily 57 CLL cells 57 PAX5 57 luminal 57 DRD4 57 alpha synuclein gene 57 autosomal dominant disorder 57 polyomavirus 57 STAT4 57 titers 57 DNMT1 57 leukemia AML 57 colorectal carcinoma 57 elevated triglyceride levels 57 Cowden syndrome 57 gene rearrangements 57 monozygotic twin 57 eNOS 57 Plasmodium 57 plasma folate 57 susceptibility gene 57 adipogenic 57 gonadotropins 57 BRAC2 57 defective gene 56 variant rs# 56 chromosomal regions 56 Alleles 56 splice variants 56 p# mutations 56 secretory 56 cytosolic 56 F#del mutation 56 MC4R gene 56 LRRK2 gene 56 beta thalassemia 56 LIS1 56 Figure 2C 56 papillary RCC 56 methyltransferase 56 hypermethylation 56 epistasis 56 neoplasias 56 mtDNA 56 mammary tumors 56 epigenetically 56 ERK1 2 56 inhibin B 56 coding exons 56 EBNA1 56 gene APOE 56 Th2 56 S. enterica 56 telomere lengths 56 matrix metalloproteinase 56 autoantibody 56 histologic 56 inducible nitric oxide synthase 56 clonally 56 phenotypic variation 56 gametophyte 56 microfilariae 56 CXCL# 56 MDR1 56 TOP2A gene 56 syntaxin 56 carboxyl terminal 56 KRAS oncogene 56 sexually dimorphic 56 Dpp 56 mtDNA mutations 56 Haptoglobin 56 spontaneous mutations 56 homozygous FH 56 pCR 56 isotypes 56 SCN5A 56 atopic 56 subtypes 56 autoreactive 56 hydroxylase 56 HER2 amplification 56 μ opioid receptor 56 RUNX3 56 WNK1 56 squamous 56 breast cancer subtypes 56 Abl 56 histopathological 56 pRb 56 alanine aminotransferase ALT 56 1 diabetes T1D 56 colorectal neoplasia 56 pyruvate kinase 56 epigenetic silencing 56 proteolytic cleavage 56 neuroblastomas 56 glycosylated 56 CpG island 56 NNRTI resistant virus 56 gene 56 abnormal chromosome 56 HMGA2 56 Serum concentrations 56 hypogonadal 56 glutamic acid decarboxylase 56 p# activation 56 sequence homology 56 Pgp 56 μmol L 56 GLUT1 56 TRAF1 C5 56 HLA DRB1 56 chromosomal abnormalities 56 human leukocyte antigen 56 monocytic 56 TNFalpha 56 nucleotide substitutions 56 Mutational 56 TGF β1 56 GNAQ 56 mediated apoptosis 56 S#A# [002] 56 familial pancreatic cancer 56 prothrombotic 56 fetal hemoglobin 56 Hh 56 CD#b 56 MDA MB 56 congenital adrenal hyperplasia CAH 56 RRM1 56 genetic polymorphisms 56 X chromosomes 56 DLC1 56 apolipoprotein E APOE 56 TET2 56 clonal 56 Polymorphism 56 TYMS 56 homodimers 56 rDNA 56 chromosomal alterations 56 monocyte 56 perivascular 56 proapoptotic 56 DR4 56 thymosin 56 HLA DR4 56 CCL#L# 56 PRNP 56 SLC#A# gene [002] 56 serine protease 56 leukemic stem cells 56 epithelia 56 STAT1 56 amino terminal 56 CCL2 56 mutant p# 56 TRIM5 56 transgenic mouse models 56 miR# 56 5 HTT gene 56 lymphovascular invasion 56 #q#.# deletion syndrome 56 midgut 56 heterotaxy 56 aggrecan 56 mutated BRCA1 56 immunohistochemical 56 ob ob mice 56 mGluR 56 gastric carcinomas 56 immunodeficient 56 mitogen activated protein kinase 56 HIV HCV coinfected 56 genetic mutation 56 SLC#A# [001] 56 Transgenic Mice 56 hippocampal neurons 56 differentially regulated 56 p# p# 56 littermates 56 Bacteroides 56 CD# CD# 56 advanced neoplasia 56 E#F# 56 db db mice 56 PIK3CA 56 postnatally 56 thyroid hormone levels 56 FDG uptake 56 Immunohistochemical staining 56 CIN2 + 56 trisomy 56 TEL AML1 56 aldehyde dehydrogenase 56 3'UTR 56 mRNAs 56 G#D 56 P. gingivalis 56 supratentorial 56 postsynaptic 56 H. influenzae 56 glomerular 56 tumor suppressor gene 56 aneuploidies 56 viremia 56 HBeAg 56 ENPP1 56 cDNAs 56 endometrioid 56 ALK gene 56 antibody titers 56 papillomas 56 BRCA2 56 Overexpression 56 pathogenic mutations 56 #ß 56 normotensive 56 Hurthle cell 56 HLA molecules 56 O methyltransferase 56 1alpha 56 IgG antibody 56 Fig. 1B 56 protein isoforms 56 inhibitory receptor 56 CatB 56 liver metastasis 56 Phosphorylation 56 ductal lobular 56 protein tyrosine phosphatase 56 HTLV 56 Gleevec resistant 56 proteolytic processing 56 vWF 56 gene encoding 56 methylated DNA 56 phylogenetic analyzes 56 neuroD2 56 colocalization 56 intraperitoneal injection 56 KCNH2 56 basal forebrain 56 proteolysis 56 astrocytic 56 vesicular stomatitis virus 56 neuroblasts 56 fig. S4 56 cellularity 56 HPV# 56 succinate dehydrogenase 56 Trichophyton rubrum 56 plasmacytoid 56 ORFs 56 COMT 56 EGFR protein 56 essential thrombocythemia 56 catenin 55 NRTIs 55 quantitative trait loci 55 homologous 55 splenocytes 55 FADS2 gene 55 autosomal recessive disorder 55 p# deficient 55 TMPRSS2 ERG 55 malignant lymphoma 55 HLA DR2 55 HMGA1 55 narcolepsy cataplexy 55 NFkB 55 HCV infected 55 deacetylation 55 TP# gene 55 hyper IgE syndrome 55 neurofibromas 55 biochemical relapse 55 IDH1 mutation 55 leukemia CLL 55 mesotheliomas 55 testis 55 chronic eosinophilic leukemia 55 neoplastic cells 55 receptor blocker 55 ovules 55 melanocyte 55 taxa 55 transgene 55 parkin gene 55 estrogen receptor negative 55 #q# deletion 55 cytidine 55 polygenic 55 prion gene 55 C. neoformans 55 transactivation 55 GenBank accession 55 CD4 + CD8 + 55 vivax 55 apolipoproteins 55 JAK2 V#F 55 BRAF protein 55 albicans 55 histologic subtype 55 Enterobacteriaceae 55 brain lesions 55 Sprague Dawley rats 55 caveolin 1 55 cognitively normal 55 ASCUS 55 Notch1 55 dimeric 55 serotonin transporter gene 55 JAK2 gene 55 CD# expression [002] 55 orthologous genes 55 ENaC 55 somatostatin 55 G6PD 55 HER2 expression 55 HRCT 55 phenotypic 55 BCL#A 55 PC# cells 55 pheochromocytoma 55 LDL receptor 55 cisplatin resistant 55 hypercholesterolemic 55 poor metabolizers 55 DNA methyltransferase 55 DAT1 55 serologic 55 hemagglutinin H 55 HER2/neu 55 immunohistochemical staining 55 neuroblastoma cells 55 cytosine 55 chromosome #p# [001] 55 oncoproteins 55 prion protein gene 55 trinucleotide 55 cynomolgus monkeys 55 ligand receptor 55 susceptibility genes 55 multivariable analysis 55 claudin 55 Sjögren syndrome 55 MeCP2 gene 55 Plasmodium falciparum