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(Click for frequent words.) 74 nucleosome 73 chromatin structure 72 chromatin 72 histones 71 Cdc# 71 E cadherin 70 acetylation 70 histone H3 70 ubiquitin 70 mRNA 70 histone protein 69 ubiquitination 69 tubulin 69 heterochromatin 69 cadherin 69 proteins 69 histone proteins 68 ubiquitylation 68 dynamin 68 phosphorylated 68 cohesin 68 phosphorylates 68 mRNAs 68 glycoproteins 67 myosin 67 proteolysis 67 intron 67 catenin 67 Myc 67 centromere 67 calpain 67 Wnt signaling 67 histone modifications 67 transcription factor 67 glutamate receptor 67 ubiquitin ligase 67 PrP 67 microtubule 67 Polycomb 67 beta catenin 67 Rab# 67 actin cytoskeleton 67 Skp2 66 methylation 66 F actin 66 transcription factors 66 H#K# [002] 66 tropomyosin 66 p# protein 66 overexpression 66 Src 66 Foxp3 66 centrosome 66 SUMOylation 66 transcriptional repressor 66 cofilin 66 alpha synuclein 66 EZH2 66 HOTAIR 66 p# [001] 66 ubiquitins 66 mutant protein 66 isoforms 66 LRP6 66 caveolin 1 66 actin 66 RhoA 65 phosphorylation 65 presynaptic 65 AMPA receptors 65 E3 ubiquitin ligase 65 integrin 65 miR #a [002] 65 exocytosis 65 cytokinesis 65 rRNA 65 MAPK 65 transcriptional activation 65 cytoskeletal 65 PIP3 65 Runx2 65 Notch signaling 65 MyoD 65 receptor molecule 65 uPAR 65 H#K#me# 65 endonuclease 65 cell motility 65 ERK1 2 65 tumor suppressor protein 65 glycosylation 65 Smad3 65 integrins 65 myosin VI 65 Mcl 1 65 tau protein 65 RNAs 65 amino acid residues 65 enzymatic activity 65 proteases 65 SGK1 65 TGF β 65 tRNA 65 Rab5 65 gamma secretase 65 NEDD8 65 HDACs 65 oncoprotein 65 genes encoding 65 nucleosomes 65 MT1 MMP 65 GAPDH 65 cytochrome c 65 telomeric 65 FOXO3a 65 STAT1 64 receptor 64 plasma membrane 64 DNA methylation 64 c myc 64 FOXO 64 histone H4 64 Oct4 64 DNMT1 64 mRNA expression 64 FGF# 64 ligases 64 proteasome 64 STAT3 64 signaling pathway 64 adhesion molecule 64 TAp# 64 SATB1 64 XBP1 64 miR# 64 acetyl groups 64 osteocalcin 64 endoplasmic reticulum 64 transmembrane 64 endocytic 64 glutamate receptors 64 gp# [002] 64 intracellular signaling 64 SWI SNF 64 MeCP2 64 membrane protein 64 cytosolic 64 miRNA expression 64 Cyclin D1 64 pRb 64 fibronectin 64 MDM2 64 PcG 64 #BP# 64 CD1d 64 phosphatase 64 glycoprotein 64 cytoplasmic 64 β 64 tyrosine phosphorylation 64 cyclins 64 E#F# 64 chromatin remodeling 64 MMPs 64 subunit 64 cyclin B1 64 miR #b [002] 64 focal adhesions 64 Ago2 64 clathrin 64 homodimer 64 coiled coil 64 paxillin 64 β catenin 64 dynein 64 postsynaptic 64 homologs 64 VE cadherin 64 mutant SOD1 64 microglial 64 alpha subunit 64 TGF ß 64 methyl groups 64 MEF2 64 Dicer 64 SOD1 63 miRNAs 63 ATPase 63 activin 63 melanocyte 63 occludin 63 intracellular 63 protein complexes 63 Hox genes 63 RNAP 63 Notch1 63 coactivator 63 extracellular 63 estrogen receptor 63 microtubules 63 beta subunit 63 centromeres 63 ligand 63 huntingtin 63 messenger RNA 63 BMP signaling 63 mitogen activated protein kinase 63 cAMP 63 cyclin 63 FAK 63 neuronal cell 63 epigenetic silencing 63 Abeta 63 substrate specificity 63 Aβ 63 c Myc 63 neurite outgrowth 63 polymerases 63 amino terminal 63 vimentin 63 homodimers 63 phagocytosis 63 transcriptionally 63 RNA polymerase 63 cytoplasmic domain 63 E3 ligase 63 dimer 63 dimerization 63 Vps# 63 APOBEC3G 63 transcriptional regulation 63 RNA splicing 63 RNA polymerases 63 demethylase 63 histone methylation 63 glycolipids 63 deacetylation 63 cyclin D1 63 Golgi 63 myosin II 63 Rap1 63 GRP# 63 molecule 63 RNA polymerase II 63 hypermethylation 63 GluR1 63 caspases 63 protein synthesis 63 receptor gene 63 ß catenin 63 fatty acid synthesis 63 matrix metalloproteinase 63 chloroplast 63 protein 63 MDSCs 63 GLI1 63 BCL6 63 KLF4 63 tumor suppressor gene 63 metabolic enzymes 63 Ubx 62 subcellular localization 62 ubiquitin molecules 62 mammalian cells 62 p#Kip# 62 TRF1 62 RNA molecule 62 X inactivation 62 IFN gamma 62 proapoptotic 62 c MYC 62 protease 62 downregulated 62 lysine residues 62 immunoreactivity 62 ABCA1 62 dystroglycan 62 PAK1 62 miRNA 62 gp# [001] 62 HBx 62 phosphorylate 62 colocalization 62 GLUT4 62 ERK2 62 5 hydroxymethylcytosine 62 PKC delta 62 PDGFR 62 GTPase 62 peptide 62 Jhdm2a 62 centrosomes 62 glycan 62 constitutively 62 autophagic 62 thioredoxin 62 tetramer 62 cyclic AMP 62 piRNAs 62 vascular endothelial cells 62 kinase domain 62 Wnt 62 JAK STAT 62 Phosphorylation 62 cofactor 62 AMPA receptor 62 p# MAPK 62 RNA molecules 62 dimers 62 helices 62 protein fragment 62 actin filaments 62 PKD1 62 estrogen receptor alpha 62 LIS1 62 untranslated regions 62 Aß 62 RNA strand 62 chromosomal translocation 62 Smoothened 62 enzyme 62 paralogs 62 ERK1 62 subunits 62 amyloid fibrils 62 B7 H1 62 IL 1beta 62 actin binding 62 mitotic 62 homolog 62 messenger RNAs 62 c Src 62 polypeptides 62 heparan sulfate 62 DISC1 62 ribosomal protein 62 RecA 62 TORC2 62 caveolae 62 histone modification 62 MAPK pathway 62 MMP9 62 phosphatidylinositol 62 laminin 62 centromeric 62 superfamily 62 SIRT3 62 upregulated 62 6S RNA 62 proto oncogene 62 clusterin 62 conformational 62 effector 62 apoptotic 62 constitutively active 62 polyadenylation 62 PIP2 62 apoptotic cells 62 calmodulin 62 metaphase 62 RAD# [001] 62 alternative splicing 62 caveolin 62 iNOS 62 TFIIH 62 ERK signaling 62 morphogen 62 tumor suppressor genes 62 tumor suppressor p# 62 chaperone proteins 62 oligomeric 61 Wnt pathway 61 Wnt proteins 61 striatal 61 synapse formation 61 neuroblastoma cells 61 auxin 61 Hox gene 61 helicase 61 microRNA molecules 61 Nedd4 61 BMP4 61 evolutionarily conserved 61 Hedgehog signaling 61 monocyte 61 Arp2 3 61 apoE 61 heterodimers 61 Th2 61 disulfide bond 61 genomic instability 61 ganglioside 61 micro RNAs 61 endocytosis 61 phosphatases 61 Sox# 61 oxidative phosphorylation 61 signaling molecule 61 neuromuscular junction 61 viral RNA 61 intronic 61 conformational changes 61 hTERT 61 exon 61 presenilin 61 riboswitch 61 receptor tyrosine kinase 61 EphA2 61 IKKß 61 epithelial 61 PTPN# 61 fission yeast 61 biogenesis 61 catalytic subunit 61 synthase 61 transactivation 61 gene transcription 61 MAP kinase 61 kinesin 61 syntaxin 61 mitotic spindle 61 organelle 61 glycans 61 ribosomal proteins 61 Cdk5 61 Nup# 61 ligands 61 HDAC 61 utrophin 61 nucleotide 61 carboxyl terminal 61 actin filament 61 mesoderm 61 P cadherin 61 IGF 1R 61 cilium 61 CXCL# 61 epithelial cell 61 ATF2 61 isoform 61 ceramide 61 Supplementary Fig 61 cathepsins 61 XBP 1 61 vesicle 61 survivin 61 E1A 61 regulates gene expression 61 secretase 61 membrane fusion 61 IL 1β 61 TGFβ 61 S#A# [002] 61 centrioles 61 adhesion molecules 61 cathepsin B 61 BACE1 61 methyl 61 transmembrane domains 61 inhibitory 61 Fig. 1C 61 aromatase 61 FGFR3 61 epitope 61 ribonuclease 61 matrix metalloproteinases 61 RANKL 61 tumorigenesis 61 Ca2 + 61 Pol IV 61 Pax6 61 cdk5 61 Fig. 3b 61 metalloproteinases 61 prion protein 61 chromosomal DNA 61 H2AX 61 PP2A 61 topoisomerase 61 Akt1 61 cysteine 61 HtrA2 61 miR 61 heterochromatic 61 NF kB 61 amino acid substitutions 61 mutant proteins 61 palytoxin 61 endosomal 61 budding yeast 61 TERT 61 VEGF receptor 61 noncoding 61 tRNA synthetase 61 neuropilin 61 oligomer 61 S#K# 61 dsRNA 61 CEACAM1 61 LDL receptor 61 overexpressed 61 NF κB 61 3'UTR 61 ESCRT 61 N cadherin 61 lysosome 61 ER alpha 61 KaiC 61 HSP# 61 vinculin 61 spectrin 61 posttranslational modifications 61 p# gene 61 capsid 61 messenger RNAs mRNAs 60 Argonaute 60 DLC1 60 lamin 60 repressor 60 mRNA transcripts 60 ERBB2 60 ligase 60 forkhead 60 protein phosphatase 60 hyperactivation 60 c Myb 60 androgen receptor 60 BH3 60 tumor suppressor 60 endosome 60 epithelia 60 nucleolus 60 laforin 60 polymerase 60 Rad# 60 ncRNAs 60 Wnt beta catenin 60 miRNA genes 60 PAX5 60 HDAC2 60 FUS1 60 H#K# [001] 60 receptors 60 dopamine receptor 60 oncogenes 60 EF Tu 60 NHEJ 60 stromal cells 60 serine 60 arginase 60 GSK 3ß 60 Htt 60 intracellular proteins 60 Hh 60 nucleolar 60 PGE2 60 IRF5 60 casein kinase 60 DNA demethylation 60 BMAL1 60 transcriptional machinery 60 protein kinase 60 TGF beta 60 epigenetic 60 telomerase activity 60 pre mRNA splicing 60 TNFalpha 60 Wnt1 60 cyclin E 60 mice lacking 60 MAPKs 60 eNOS 60 IKKa 60 p# activation 60 adherens junctions 60 gene expression 60 nicotinic receptors 60 prion proteins 60 Hsp# [001] 60 mRNA translation 60 exons 60 morphogens 60 Histone 60 histone deacetylases 60 WT1 60 ubiquitinated 60 annexin V 60 coding RNA 60 tyrosine kinase 60 cell adhesion 60 microRNAs miRNAs 60 cypin 60 protein kinase C 60 tRNAs 60 serotonin receptor 60 topoisomerases 60 neuroligin 60 matrix metalloproteinases MMPs 60 oncogenic 60 cysteines 60 Syk 60 insulin receptors 60 ciliated 60 protein encoded 60 heterodimer 60 FtsZ 60 phenotype 60 ribosomal RNA 60 kinetochores 60 transgene expression 60 HSF1 60 LRRK2 60 oligomers 60 receptor subunit 60 FGF2 60 glial 60 serine threonine 60 retinoic acid 60 molecular pathway 60 gene p# 60 phytochrome 60 Akt 60 XPB 60 synaptogenesis 60 IL 1ß 60 membrane proteins 60 transmembrane protein 60 mTOR signaling 60 vesicle fusion 60 LKB1 60 adduct 60 SREBP 60 introns 60 microRNAs 60 TRAF6 60 anti apoptotic 60 CpG 60 nuclease 60 costimulatory 60 cytosine 60 cell adhesion molecules 60 p#NTR 60 binding proteins 60 cell signaling pathways 60 SIRT2 60 chromosomal instability 60 alanine 60 amyloid beta peptides 60 NKG2D 60 PPARg 60 caspase 60 Pten 60 intramolecular 60 coactivators 60 OCT4 60 thiol 60 noncoding RNAs 60 MEK1 60 astrocytes 60 dopamine transporter 60 cytochrome 60 histone acetylation 60 GSK3 60 fibrils 60 Dpp 60 4E BP1 60 NMDA receptor 60 cellular metabolism 60 Sp1 60 AMACR 60 Vpr 60 β amyloid 60 Pin1 60 receptor proteins 60 histidine 60 amyloids 60 oxidase 60 methyltransferases 60 CD# [002] 60 hippocampal neurons 60 protein tyrosine kinase 60 PTEN gene 60 transgenic mice 60 primary cilium 60 SIRT6 60 noncoding RNA 60 valine 60 immunodominant 60 viral genome 60 oligomerization 59 PTEN protein 59 HDAC6 59 titin 59 cellular senescence 59 amyloid precursor protein 59 ligand binding 59 Fig. 1A 59 TSLP 59 lysosomal 59 eukaryotic cells 59 focal adhesion kinase FAK 59 epigenetic modifications 59 neural crest cells 59 TIR1 59 methylated DNA 59 non coding RNA 59 dendrite 59 fibril 59 nucleolin 59 CTCF 59 EGF receptor 59 myeloid cells 59 MALAT1 59 methylated 59 tyrosine 59 c fos 59 RUNX3 59 nucleotide sequence 59 flavin 59 meiotic 59 fluorescent molecules 59 microRNA miR 59 neuronal 59 PHD2 59 Wnts 59 pyrrolysine 59 NFκB 59 apoE4 59 neurofibrillary tangles 59 TrkB 59 FoxO1 59 homologous 59 ADAM# 59 signaling cascade 59 synaptic transmission 59 arginine residues 59 Vpu 59 DNA polymerase 59 CFTR 59 ß amyloid 59 recombinase 59 palladin 59 thrombospondin 59 peptides 59 endonucleases 59 CDK5 59 KLF2 59 dephosphorylation 59 protein filaments 59 rhodopsin 59 proinsulin 59 S1P 59 antigen binding 59 Rac1 59 downstream effector 59 GATA3 59 EBNA1 59 Microtubule 59 sRNA 59 protein p# 59 NFAT 59 axon guidance 59 granzyme B 59 HIF 1a 59 cellular pathways 59 serine protease 59 upregulation 59 mitotic progression 59 TLR2 59 epigenetic modification 59 serotonin transporter 59 chromophore 59 homologous recombination 59 3' UTR 59 transcriptional 59 insulin receptor 59 lymphocyte 59 transmembrane receptor 59 Bcl xL 59 secretory pathway 59 hnRNP 59 RNA sequences 59 Mdm2 59 SIRT1 59 Golgi apparatus 59 TACI 59 TLR4 59 acetyl CoA 59 ACh 59 IRE1 59 C1q 59 interneurons 59 overexpressing 59 fibrillar 59 ERa 59 podocytes 59 KLF# 59 UTRs 59 PMR1 59 calpastatin 59 PTP1B 59 catalase 59 NF kappaB 59 SH#B# 59 alpha synuclein gene 59 pDCs 59 receptor signaling 59 signaling pathways 59 osteoblast 59 ribosomal 59 Cdx2 59 fatty acid synthase 59 PHLPP 59 dimeric 59 nucleolar dominance 59 granule cells 59 JAK2 59 amyloid β 59 constitutively expressed 59 alternatively spliced 59 calcineurin 59 RNA transcripts 59 kinase enzymes 59 adipogenesis 59 biosynthesis 59 coiled coil domain 59 PDZ domains 59 eIF4E 59 BCL2 59 amyloid beta 59 SCD1 59 operon 59 SOCS3 59 telomere 59 Rb#/p# 59 PcG proteins 59 actin polymerization 59 Dysregulation 59 Nrf2 59 cysteine residues 59 eotaxin 59 glucocorticoid receptor 59 importin 59 DARPP 59 amyloid beta protein 59 oncogene 59 neural crest 59 lectin 59 cytosol 59 inhibitory receptor 59 TNFR 59 Sonic hedgehog 59 ectopic expression 59 EGFP 59 procaspase 3 59 downregulation 59 catalytically active 59 biomolecule 59 DNA methyltransferases 59 chromatid 59 myofibroblasts 59 Cathepsin B 59 HLA molecules 59 metalloproteinase 59 mutant huntingtin 59 messenger RNA mRNA 59 kinase 59 TGF b 59 var genes 59 beta arrestin 59 non coding RNAs 59 chromatin remodeling complex 59 3' 59 pyrimidine 59 GPR# [002] 59 microRNA molecule 59 cAMP signaling 58 semaphorin 58 MLL gene 58 PGC 1α 58 focal adhesion 58 PDZ domain 58 telomerase RNA 58 SVZ 58 TLE3 58 progerin 58 PI3 kinase 58 subcellular 58 Mre# 58 adhesion proteins 58 dehydrogenase 58 filopodia 58 epigenetically 58 coexpression 58 cortical neurons 58 gene encoding 58 mutant p# 58 TGF beta pathway 58 synuclein 58 trophoblast cells 58 radial glia 58 Methylation 58 FKBP# 58 plasminogen 58 HERV 58 protein tyrosine phosphatase 58 ncRNA 58 myogenesis 58 amino acid 58 biochemical pathway 58 Wnt signaling pathway 58 neuronal migration 58 NR2B 58 RNA binding 58 mitochondrial gene 58 ssDNA 58 phospholipase 58 mitochondrial respiration 58 TGFb 58 Schwann cells 58 Ku# 58 transferase 58 adipocyte 58 guanosine 58 nucleases 58 synthases 58 fig. S1 58 caspase activation 58 neurones 58 cytokine 58 primary cilia 58 PKM2 58 HipA 58 secretory 58 cardiomyocyte 58 ectodomain 58 HIP1 58 ErbB2 58 p# p# 58 glial cell 58 NMDA receptors 58 Akt activation 58 Sir2 58 receptor gamma 58 pro apoptotic 58 bacterial enzyme 58 HIF 1alpha 58 PKC isoforms 58 cultured cells 58 ADDLs 58 RAR beta 58 GABAergic 58 LSD1 58 histone deacetylation 58 neuronal differentiation 58 SH2 B 58 C EBP alpha 58 Cx# [001] 58 lymphoid cells 58 protein ubiquitin 58 CaM 58 miR #b [001] 58 P selectin 58 binding affinities 58 receptor protein 58 isoleucine 58 PPARγ 58 uracil 58 leukocytes 58 Alu elements 58 BCR ABL 58 apoptotic pathway 58 beta globin 58 MMP# 58 nAChR 58 molecule binds 58 DNA methylation patterns 58 farnesyl 58 homology 58 methyltransferase 58 breast epithelial cells 58 neurofilament 58 serotonin receptors 58 ERK 58 selenoproteins 58 PI3K Akt 58 podocyte 58 inducible nitric oxide synthase 58 monocytes 58 Purkinje cell 58 operons 58 HSCs 58 transgenic mouse model 58 ligand receptor 58 glomerular 58 chemokine receptor 58 structural rearrangements 58 microglial activation 58 antigen receptor