Related by context. All words. (Click for frequent words.) 77 inhibiting 76 inhibits 72 inhibited 70 impede 69 hinder 64 impair 61 selectively inhibit 61 inhibit tumor 61 hamper 60 impedes 59 potentiate 58 modulate 57 upregulate 57 hinders 57 stifle 57 suppresses 56 inhibits tumor 55 inhibition 55 constrain 55 potent stimulator 54 impairs 54 induce apoptosis 54 induce 54 stimulates 54 inhibited tumor 54 inhibiting tumor 54 tumor suppressor PTEN 54 stimulate 53 aldose reductase 53 detoxify harmful 53 mitogenic 53 downregulate 53 thereby inhibiting 53 prostaglandin E2 PGE2 53 suppresses tumor 53 MetAP2 52 osteoclast formation 52 interfere 52 cytoprotective 52 CDK5 52 negatively affect 52 Src kinase 52 chloride channels 52 attenuate 52 adversely affect 52 inhibitor 52 suppress 52 FGFs 52 cathepsins 52 PDGF alpha receptor 52 overactivated 52 upregulates 52 potent activator 52 retarding 52 undermine 52 impeding 52 inhibit viral replication 52 discourage 52 JAK#/JAK# 52 inhibiting COX 52 activate p# 52 regulate gene expression 52 MT1 MMP 52 dampen 52 inhibit microbial 51 inhibits bacterial 51 stimulate insulin secretion 51 Inhibiting 51 efflux pumps 51 inhibitory 51 hindered 51 factor NGF 51 5 HT2A serotonin 51 potentiating 51 endothelial nitric oxide 51 enzyme acetylcholinesterase 51 inhibitors 51 negatively impact 51 potent inhibitors 51 potently inhibited 51 inhibit bacterial 51 glucocorticoid receptor 51 selectively inhibited 51 cyclin B1 51 S#K# 51 PPARg 51 restrict 51 #HT#A receptor 50 microsomal 50 Myostatin 50 neurotransmitter receptors 50 disrupt 50 histone deacetylation 50 COX enzymes 50 histone deacetylases HDACs 50 orexin receptors 50 coactivators 50 PPARγ 50 cyclooxygenase COX 50 TXNIP 50 matrix metalloproteinases 50 inhibitory effects 50 Hsp# chaperone 50 stymie 50 inhibit angiogenesis 50 protein CETP 50 potent inducer 50 NK1R 50 induce angiogenesis 50 MMP2 50 inhibit enzymes 50 secreted proteins 50 antimetastatic 50 detrimental 50 HDAC2 50 hindering 50 retard 50 Dr. Ivashkiv 50 Treg cells 50 act synergistically 50 renin angiotensin system 50 HepG2 cells 50 Preclinical studies suggest 50 thromboxane A2 49 nitric oxide synthase 49 BRAF kinase 49 curtail 49 TRPV1 receptors 49 casein kinase 49 ERK5 49 neuromuscular junction 49 interferes 49 nicotinic 49 Androgen receptor 49 attenuates 49 β catenin 49 Gleevec inhibits 49 affect 49 inhibit replication 49 misregulation 49 impairing 49 gamma aminobutyric acid 49 thrombin receptor 49 ERK pathway 49 angiotensin II receptor 49 thromboxane 49 impeded 49 prostaglandin synthesis 49 serine proteases 49 metabolize cholesterol 49 inhibitory neurotransmitters 49 NF kappaB activation 49 dendritic spine 49 potently inhibit 49 cholesterol homeostasis 49 Hsp# chaperone system 49 inactivate 49 immunomodulatory effects 49 Hh pathway 49 secrete proteins 49 neurotrophic 49 MAP kinase 49 calpain 49 inhibitory effect 49 inactivates 49 induces 49 spur 49 acetylcholinesterase 49 pleiotropic 49 pro oxidant 49 actin cytoskeleton 49 Hedgehog pathway 49 chemically modify 49 lysyl oxidase 49 neuronal apoptosis 48 Wnt signaling pathway 48 myeloid derived 48 exacerbate 48 constitutively active 48 transcriptional activity 48 NF KappaB 48 stifles 48 depress 48 mutant huntingtin protein 48 #HT#A 48 histone deacetylases 48 HIF PH 48 peptide hormones 48 inhibit vascular endothelial 48 factor PDGF 48 pro angiogenic 48 inhibitory molecules 48 phosphorylate 48 preclude 48 CB1 receptor 48 ERK1 2 48 c myc gene 48 glutamate receptors 48 hedgehog pathway 48 constrict 48 Akt signaling 48 TRPV1 receptor 48 COX2 48 selective inhibition 48 mu receptor 48 downregulates 48 GABA aminotransferase 48 TrkB 48 inducible 48 mitochondrial pore 48 intracellular protein 48 inhibit tumor angiogenesis 48 trans splicing 48 neuro protective 48 interleukin 1beta 48 cyclic AMP cAMP 48 anti tumoral 48 CRAC channel 48 heme oxygenase 48 stimulated 48 eicosanoid 48 beta endorphin 48 potent anti oxidant 48 PKC alpha 48 Integrins 48 isoenzymes 48 stellate cells 48 eIF4E 48 Bcl 48 peroxisome 48 leukotrienes 48 Flt3 48 PDGF receptor 48 secreted protein 48 P#Y# receptor 48 inhibit VEGF 48 galanin 48 viral proteins 48 cytokine signaling 48 calcitonin gene related 48 toxic beta amyloid 48 predispose 48 acyl CoA 48 p# MAPK 48 excitotoxic 48 mitochondrial enzymes 47 curtails 47 impair fertility 47 underlie 47 perturb 47 serotonin uptake 47 intracellular pathways 47 modulate gene expression 47 dampens 47 histone deacetylase HDAC 47 heparanase 47 ephrin A1 47 enzyme aromatase 47 phosphatases 47 IL #p# 47 HMG CoA reductase 47 HIV reverse transcriptase 47 SIRT2 47 FKBP# 47 5 lipoxygenase 47 MAPK signaling pathway 47 detrimentally affect 47 detoxify carcinogens 47 methyl D aspartate 47 autoreactive 47 RAF kinase 47 apoptosis induced 47 FOXO 47 PECAM 1 47 GSK3B 47 potentiates 47 renin angiotensin 47 BCL2 47 cyclins 47 oncogenic transformation 47 biogenic amine 47 sphingolipids 47 RANK Ligand 47 TrkA 47 MMP9 47 poly ADP ribose polymerase 47 cytolytic 47 Her-2/neu 47 mediated inhibition 47 awaken dormant 47 mRNA cleavage 47 ligand TRAIL 47 DGAT 47 superoxide radicals 47 inhibit KSP 47 chemically modifying 47 histone deacetylase 47 c Abl 47 cripple 47 Th2 cytokines 47 transcriptional repressor 47 E selectin 47 NKG2D 47 serotonin reuptake 47 NF kappaB 47 enzyme COX 47 extracellular calcium 47 adipocytes fat 47 maturation inhibitors 47 potent inhibitor 47 squelch 47 glucocorticoid receptors 47 Caspases 47 alveolar macrophage 47 cofactors 47 S6K 47 fibril formation 47 cotransporter 47 tumor vasculature 47 innervate 47 TGF beta1 47 μ opioid receptor 47 cyclic nucleotide 47 FOXO3a 47 proteolytic 47 chitinase 47 Protease inhibitors 47 potentiated 47 androgen hormone 47 lipid synthesis 47 NO synthase 47 Hedgehog signaling 47 beta adrenergic 47 PKC inhibitor 47 antiapoptotic 47 synthetic fertilizers hormones 47 ARF1 47 tumor stroma 47 adenosine receptor 47 cytotoxic T lymphocyte 47 angiotensin receptor 47 cdk5 47 VEGF pathway 47 uPAR 47 deter 47 metalloproteinase 47 CCR2 47 prostaglandin E2 47 oncoproteins 47 potent suppressor 47 aberrant activation 47 gamma amino butyric 47 autocrine 47 NKT cells 47 hampering 47 mu opioid receptors 47 enzyme cyclooxygenase 47 lysosomal 47 Vpr 47 c MYC 47 airway epithelial 47 cyclooxygenase 2 47 overactivation 47 Hsp# [001] 47 eotaxin 47 allosteric 47 Inhibit 47 CB1 receptors 47 secretase 47 TGFβ 47 tetherin 47 xanthine oxidase 46 AT1R 46 IAP inhibitor 46 inactivating 46 mTOR mammalian target 46 HIF 1alpha 46 enzyme inhibitor 46 matrix metalloproteinases MMPs 46 oxidant stress 46 RAS RAF MEK 46 CaMKII 46 adversely impact 46 FasL 46 estrogen receptor beta 46 toxic amyloid beta 46 platelet activation 46 induced neuronal 46 NMDA receptors 46 NF KB 46 habenula 46 dysregulated 46 inflammatory cytokines 46 proapoptotic 46 enkephalin 46 cyclic adenosine monophosphate cAMP 46 LTB4 46 tumor angiogenesis 46 synaptogenesis 46 protein kinase C 46 cytoskeletal 46 glucagon receptor 46 costimulation 46 factor EGF 46 Aâ 46 chemical acetylcholine 46 Vascular Endothelial Growth 46 tumor suppressor proteins 46 PKC isoforms 46 TNFα 46 AMPA receptor 46 PP2A 46 cyclooxygenase 46 obstruct 46 potent antitumor 46 GGTase 46 enzyme beta secretase 46 SFRP1 46 GPR# receptor [002] 46 selectively inhibits 46 superoxide anion 46 toxic misfolded proteins 46 ErbB4 46 receptor inhibitor 46 D3 receptors 46 anti apoptotic 46 opioid receptors 46 clusterin protein 46 macrophage inflammatory 46 soluble amyloid beta 46 p# activation 46 proinflammatory mediators 46 CB2 receptor 46 miR #a [002] 46 NR2B subunit 46 vessel constriction 46 enkephalins 46 downregulated 46 ki ll 46 TMEM#B 46 ligases 46 CDK4 46 paracrine 46 jeopardize 46 AMP kinase 46 hormone secretion 46 activate AMPK 46 D2 receptor 46 pro apoptotic 46 transferrin receptors 46 branching morphogenesis 46 NS5A 46 cytokine IL 46 TGF ß1 46 serpin 46 protease enzyme 46 cyclase 46 amyloidogenic 46 potent anticancer 46 KIT mutations 46 ornithine decarboxylase 46 endogenous 46 neurotrophic factors 46 Cdc7 46 lymphotoxin 46 hormone angiotensin II 46 immune effector 46 selectively inhibiting 46 palmitoylation 46 teratogens 46 CRF receptors 46 inflammatory cytokine 46 Rho GTPases 46 diminish 46 secrete chemicals 46 metabolizing enzymes 46 PTP1B 46 downregulating 46 gamma secretase 46 digesting enzymes 46 leukocyte recruitment 46 neurite outgrowth 46 bacterial enzyme 46 upregulation 46 receptor CXCR4 46 synaptic transmission 46 4E BP1 46 XL# inhibits 46 γ secretase 46 factor receptor FGFR 46 androgen receptors 46 CD8 + cytotoxic 46 Notch inhibitor 46 beta arrestin 46 EphB2 46 inflammatory mediators 46 selective agonists 46 weaken 46 SOCS3 46 p#NTR 46 PDE1 46 ameliorates 46 PI3 kinase 46 Y2 receptor 46 suppressing 46 elastase 46 mutated protein 46 cyclophilin D 46 aberrantly activated 46 CCR1 46 proton pump 46 microtubule dynamics 46 endothelin receptors 46 Notch receptor 46 selective inhibitors 46 adhesion proteins 46 protein synthesis inhibitors 46 amyloid beta peptides 46 Mechanistically 46 anti inflammatory cytokine 46 psoriatic skin 46 Tissue Factor 46 GABA receptors 46 glutamate neurotransmitter 46 Quorum sensing 46 amino acid tyrosine 46 cell adhesion molecules 46 paxillin 46 Siglec 8 46 SUMOylation 46 embryonic tissues 46 γδ T cells 46 MDMX 46 pRb 46 downstream effectors 46 AKT pathway 46 TPO receptor 45 XBP 1s 45 amyloid plaque formation 45 factor VEGF 45 treating neuropathic pain 45 inverse agonist 45 fibrogenesis 45 Smac mimetic 45 TGF ß 45 nitric oxide synthase NOS 45 growth hormone secretion 45 CCR3 45 Factor VEGF 45 inhibit blood clotting 45 deters 45 PEPCK 45 inhibiting enzymes 45 EETs 45 caspase activation 45 pro inflammatory cytokines 45 proliferation apoptosis 45 receptor PPAR 45 mTORC1 45 IGF1R 45 KATP channels 45 LDL receptors 45 HER2 neu 45 phosphoinositide 45 CCL# 45 β1 45 mineralocorticoid 45 epithelial barrier 45 tyrosinase 45 mTOR signaling 45 ERa 45 serine threonine 45 beta amyloid peptide 45 neurotransmission 45 PI3K/Akt pathway 45 topoisomerase II 45 c myb 45 ENaC 45 Lyn kinase 45 transcriptional activation 45 gastrin 45 pro inflammatory cytokine 45 inhibit platelet aggregation 45 alveolar macrophages 45 NKX#.# 45 dopamine transporter DAT 45 mitochondrial enzyme 45 granzyme B 45 protein tyrosine kinases 45 Notch receptors 45 CDK8 45 IFN γ 45 Sertoli cell 45 HSF1 45 therapeutically relevant 45 5 HT2A inverse 45 aminobutyric acid 45 CXCL5 45 N Myc 45 muscarinic receptors 45 antitumoral 45 FGFR4 45 PI3K signaling 45 complicate 45 45 enzymatic pathway 45 cytokines 45 potent inhibition 45 counteracts 45 molecular chaperone 45 LRP1 45 receptor subtypes 45 induces apoptosis 45 integrin receptors 45 integrin alpha 4 45 lipoxygenase 45 glucokinase 45 pyramidal cells 45 druggable target 45 TGR5 45 selective modulator 45 causally linked 45 GABAA receptors 45 serotonin receptor 45 enzyme inhibitors 45 sphingolipid 45 TGF beta 45 VEGF signaling 45 antiviral cytokines 45 tropomyosin 45 apoptosis inducing 45 adenylate cyclase 45 cyclin dependent kinase inhibitor 45 EGFR pathway 45 mesenchymal cell 45 intestinal epithelial cells 45 neuronal dysfunction 45 metalloproteinases 45 SNAREs 45 dopamine D1 45 factor HGF 45 breast carcinogenesis 45 hepatic glucose 45 chaperone protein 45 TGFbeta 45 Treg cell 45 protein secretion 45 HDAC6 45 MAPK pathway 45 CEACAM1 45 opiate receptors 45 immunoregulatory 45 PDGFR 45 activin 45 virulence genes 45 VEGF receptor 45 radioprotective 45 prostanoid 45 fibrotic disease 45 LDL receptor 45 IFNg 45 HDACs 45 Eg5 kinesin motor 45 posttranslational 45 HIF 1a 45 DNA methyltransferases 45 mevalonate 45 disrupts 45 stimulate neurogenesis 45 degrading enzyme 45 TGF beta signaling 45 protease enzymes 45 GABAergic 45 degranulation 45 GATA3 45 Inhibitory 45 SWI SNF 45 Fibroblast Growth Factor 45 ER alpha 45 5 HT2A receptor 45 endoplasmic 45 leukocyte adhesion 45 Ras MAPK pathway 45 neurotransmitter glutamate 45 lipopolysaccharide 45 HBx 45 NF kB pathway 45 CXCR4 receptor 45 A2A adenosine receptor 45 SGLT2 inhibitors 45 SERMs 45 factor PlGF 45 NPC#L# 45 endothelial nitric oxide synthase 45 lymphangiogenesis 45 Shp2 45 constitutively expressed 45 stimulating 45 imperil 45 HER2 receptors 45 VSMC 45 Aurora kinases 45 cytokine receptor 45 DGAT1 45 neurotrophins 45 Polycomb proteins 45 Rb#/p# 45 stimulate collagen 45 ASIC1a 45 HIF 2alpha 45 TNFR 45 CYP#B# 45 FOXP3 + 45 PHD2 44 phosphorylates 44 leukotriene 44 aromatase enzyme 44 Ang2 44 Th2 immune 44 adipokines 44 triggers apoptosis 44 DNA adducts 44 C5aR 44 TGF alpha 44 receptor gamma 44 miR #b [002] 44 Factor Receptor 44 SCD1 44 UCP1 44 chemopreventive 44 erythropoietin receptor 44 nociceptive 44 antiproliferative 44 alveolar epithelial 44 suppressor cells 44 CD#L 44 monocytes macrophages 44 vascular constriction 44 Th1 type 44 vasoconstrictor 44 catalyze 44 neuropeptides 44 soluble CD# 44 preferentially bind 44 MetAP 44 inhibit metastasis 44 CXCL# 44 regulates gene expression 44 ischemic diseases 44 isradipine 44 factor receptor EGFr 44 CTLA4 44 Osteopontin 44 endogenous opioid 44 adult neurogenesis 44 clonogenic 44 Abeta# 44 gluconeogenesis 44 excess glutamate 44 protein tyrosine kinase 44 Apo2L 44 antiangiogenesis 44 Eg5 44 dystroglycan 44 VEGF receptors 44 M1 muscarinic 44 unduly restrict 44 overexpressing 44 induced angiogenesis 44 opioid peptides 44 transmembrane receptor 44 PI3K AKT 44 proinflammatory cytokine 44 RNA polymerases 44 ERb 44 adipogenesis 44 E cadherin 44 extracellular signaling 44 MEK1 44 CTLA 4 44 GLI1 44 aff ect 44 converting enzyme 44 phagocytic 44 IKK2 44 enzyme caspase 44 CatB 44 cathepsin 44 nicotinic receptor 44 inducing apoptosis 44 PGE2 44 induced phosphorylation 44 Retinoids 44 small molecule tyrosine 44 immunomodulating 44 endothelial 44 activated macrophages 44 PDE# 44 Kinoid 44 integrin activation 44 degradative 44 IGF IR 44 hypoxia inducible 44 prolyl 44 HIF 1α 44 M1 macrophages 44 stifle creativity 44 encode proteins 44 bacterial virulence 44 Cdc# 44 VEGF vascular endothelial 44 ACh 44 myoepithelial cells 44 mGluR5 antagonist 44 COL#A# 44 cell motility 44 autophagic 44 androgen receptor AR 44 induced cytotoxicity 44 therapeutically useful 44 ErbB3 HER3 44 proinflammatory cytokines 44 NPD1 44 amyloid β 44 tumor metastasis 44 fusogen 44 oncomodulin 44 agonist induced 44 vasodilatation 44 reductase 44 PPAR alpha 44 PKCi 44 Raf kinase 44 kinase pathway 44 beta1 integrin 44 endogenous ligands 44 proteasome inhibition 44 HMG CoA 44 iNOS 44 BCL#A 44 stathmin 44 receptor tyrosine kinase 44 anti proliferative 44 fibrin deposition 44 mutant huntingtin 44 SIRT1 gene 44 electrophilic 44 hyperactivated 44 Angiotensin 44 bone morphogenetic proteins 44 restricting 44 antiproliferative activity 44 PPAR peroxisome proliferator activated 44 endogenous ligand 44 renal tubular 44 GPI anchored 44 Ii protein 44 progesterone receptor 44 C. pneumoniae 44 IFN g 44 MAPK 44 immuno modulatory 44 IKKß 44 dopamine receptor 44 Pim kinases 44 cyclic guanosine monophosphate cGMP 44 anti TNFa 44 activated lymphocytes 44 endanger 44 Ets2 44 gastric carcinomas 44 VE cadherin 44 adhesion molecule 44 JNK1 44 glycosaminoglycans 44 NADPH oxidase 44 tyrosine phosphatase 44 neuroinflammatory 44 interferon pathway 44 synapse formation 44 mTOR signaling pathway 44 CCR5 co 44 PGC 1α 44 antimitotic 44 antiviral antibacterial 44 aP2 44 cytokine 44 inosine 44 potent antibacterial 44 IGFBP 3 44 dNTP 44 ZFP TF 44 proteinase 44 coactivator 44 dehydrogenases 44 PPAR γ 44 divide uncontrollably 44 DNA gyrase 44 genotoxic stress 44 mitochondrial membrane 44 MAP kinases 44 CD# ligand 44 cholinergic neurons 44 phosphatase 44 MAO B 44 TSLP 44 IL 1β 44 inhibit platelet function 44 microglial activation 44 Th2 44 neuronal differentiation 44 VEGFR1 44 plasminogen activator 44 podocyte 44 TNFa 44 Hfq 44 plasminogen 44 E#F# 44 hormone secreting 44 lipoprotein lipase 44 colon carcinogenesis 44 CYP#A# enzyme 44 STAT1 44 PPAR gamma receptor 44 amyloid formation 44 coagulation cascade 44 ErbB2 44 tumorigenesis 44 fatty acid synthase 44 antiangiogenic 44 prostaglandin D2 44 immunostimulatory effects 44 Smoothened 44 #ß 44 catalase 44 TAT Bim 44 lymphoid organs 44 accelerate 44 glutamate transporters 44 FGF2 44 inducible nitric oxide synthase 44 intracellular signaling 44 demyelinated 44 hormone secreted 44 adversely affects 44 acetylcholine receptor 44 adeno associated viruses 44 capillary endothelial cells 44 redox active 44 isomerase 44 gyrase 44 metabolic enzymes 44 secrete hormones 44 axon outgrowth 44 serine protease 44 PI3K Akt 44 PI3K pathway 44 dilating blood 44 impinge upon 44 superantigens 44 XBP1 44 cholesterol biosynthesis 44 messenger ribonucleic acid 44 colorectal carcinogenesis 44 rolipram 44 D aspartate 44 MEK ERK 44 reuptake 44 mPGES 1 44 reversible inhibitor 44 Akt1 44 antimicrobial peptides 44 pancreatic islet 44 cell signaling pathways 44 Ellagic acid 44 induce regression 44 PAK1 44 glucose transporter 44 eNOS 44 HDAC 44 signaling pathway 44 paralyze 44 ANGPTL4 44 inhibits inflammation 44 NFκB 44 syk 44 pancreatic alpha 44 adrenoceptor 44 chemoprotective 44 modulates 44 Hedgehog signaling pathway 44 podocytes 44 potent antiproliferative 44 humanized monoclonal antibodies 44 oligomerization 44 proteolytic degradation 44 immune suppressive 44 CDKs 44 malonyl CoA