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(Click for frequent words.) 74 genes encoding 74 isoform 72 mRNA expression 72 transcription factors 71 constitutively 71 paralogs 71 cysteine residues 71 homodimers 70 phosphorylated 70 constitutively active 70 substrate specificity 70 caveolin 1 70 splice variants 70 cytosolic 70 MAPK 70 catenin 70 transmembrane protein 69 orthologs 69 somatostatin 69 proteins 69 Foxp3 69 mitogen activated protein kinase 69 Vps# 69 ERK1 69 ERK1 2 69 transmembrane 69 miRNAs 69 IFN gamma 69 uPAR 69 iNOS 69 heterodimers 69 isoenzymes 69 ERK2 69 metabolic enzymes 69 subunits 68 H#K#me# 68 overexpression 68 Rap1 68 homologs 68 tyrosine phosphorylation 68 ncRNAs 68 E cadherin 68 cyclins 68 mice lacking 68 transactivation 68 mRNA 68 Smad3 68 beta subunit 68 pRb 68 Notch1 68 transcriptional activation 68 intracellular 68 polymorphisms 68 CD1d 68 IL 1β 68 transcription factor 68 missense mutations 68 overexpressing 68 histone H3 68 transcriptional regulation 67 constitutively expressed 67 androgen receptor AR 67 upregulated 67 nucleolin 67 caveolin 67 micro RNAs 67 H#K# [002] 67 isotypes 67 PrP 67 TGF β 67 basolateral 67 TAp# 67 dimerization 67 downregulated 67 subunit 67 ligands 67 E#F# 67 mRNA molecules 67 GAPDH 67 STAT3 67 neurofilament 67 homodimer 67 epithelia 67 glucocorticoid receptor 67 Rab5 67 inhibitory receptor 67 FasL 67 Akt 67 cDNAs 67 proteins encoded 67 protein kinase C 67 KLF4 67 receptors 67 receptor subtypes 67 hTERT 67 V#F mutation 67 cadherin 67 proteolysis 67 proto oncogene 67 phosphatases 67 cells transfected 67 cytoplasmic 67 murine 67 MyoD 67 alleles 67 estrogen receptor 67 S#A# [002] 67 transcriptional repressor 67 glucose transporter 67 RNA sequences 67 ribosomal proteins 67 syntaxin 67 secretory 67 thioredoxin 67 serine protease 67 IGFBP 67 polypeptide 67 phosphorylation 67 synthase 67 neurite outgrowth 66 transduced 66 FGFR2 66 mRNAs 66 noncoding RNAs 66 CXCL# 66 phospho 66 glycosylated 66 EGFP 66 subcellular localization 66 HepG2 cells 66 dsRNA 66 Cre recombinase 66 IL 1beta 66 c myc 66 histone modifications 66 miR #a [001] 66 Cdc# 66 cell adhesion molecules 66 coactivator 66 HDACs 66 RNAs 66 eukaryotic cells 66 glycoprotein 66 Alu elements 66 MDR1 66 TGF ß 66 isozymes 66 BMP signaling 66 cathepsin B 66 phosphatase 66 CD#b 66 IGF 1R 66 vimentin 66 synuclein 66 protein kinases 66 serine threonine 66 polypeptides 66 miR 66 thrombospondin 66 phosphorylates 66 apoE 66 signaling pathways 66 SIRT2 66 superfamily 66 operon 66 transfected 66 MAPK pathway 66 c MYC 66 receptor 66 TNFalpha 66 cytochrome 66 enzymatic activity 66 Phosphorylation 66 polymerases 66 protein isoforms 66 HSCs 66 globin genes 66 gene encoding 66 GTPase 66 histone 66 presynaptic 66 EphB4 66 missense mutation 66 untranslated regions 66 peptides 66 interferon IFN 66 hydroxylase 66 ß catenin 66 exon 66 tropomyosin 66 cAMP 66 morphogen 66 proteases 65 adrenergic receptors 65 virulence genes 65 phenotype 65 ErbB2 65 mRNA transcripts 65 drug metabolizing enzymes 65 pDC 65 receptor gene 65 activin 65 microRNA miR 65 upregulation 65 potent inhibitors 65 cell adhesion molecule 65 CagA 65 serine threonine kinase 65 calpain 65 ABCA1 65 phosphorylate 65 amino acid residues 65 miRNA expression 65 EBNA1 65 mutant p# 65 Supplementary Fig 65 matrix metalloproteinase 65 RNA transcripts 65 pDCs 65 fascin 65 Kupffer cells 65 messenger RNAs mRNAs 65 tyrosine kinases 65 eotaxin 65 transgene expression 65 hippocampal neurons 65 regulated kinase ERK 65 coding genes 65 eukaryotic 65 cofactor 65 Klf4 65 cyclin D1 65 SLC#A# [002] 65 cyclin 65 extracellular signal 65 Fas ligand 65 cyclin E 65 eNOS 65 BCL2 65 ENaC 65 MDM2 65 EphA2 65 estrogen receptor alpha 65 bcl 2 65 MMPs 65 lysosomal 65 tetramer 65 MAPKs 65 serotonin receptor 65 HIF 1alpha 65 glycoproteins 65 S1P 65 HSP# 65 DNMT1 65 thymocytes 65 endonuclease 65 PAK1 65 membrane protein 65 phenotypes 65 mutant proteins 65 65 stromal cells 65 integrins 65 exocytosis 65 cytochrome c 65 DLC1 65 inducible 65 CCR7 65 paxillin 65 survivin 65 cytoplasmic domain 65 lipoxygenase 65 STAT1 65 phospholipase 65 protein tyrosine phosphatase 65 Hsp# [001] 65 PC# cells 65 MDSCs 65 alternatively spliced 65 nicotinic receptors 65 β 64 homologues 64 homozygotes 64 vascular endothelial cells 64 chromatin structure 64 Aβ 64 lymphoid cells 64 PDGFR 64 extracellular 64 rRNA 64 ligand 64 synthetase 64 transcriptionally 64 LIS1 64 lymphocyte 64 intergenic 64 laminin 64 receptor binding 64 receptor subtype 64 Kv#.# 64 promoter methylation 64 Aß 64 inhibitory activity 64 hydrolases 64 TIMP 64 melanocyte 64 leucine zipper 64 BDNF gene 64 BMP2 64 deficient mice 64 VE cadherin 64 p#Kip# 64 GLUT4 64 cyclin dependent kinase 64 SOD1 64 fibroblast 64 acetylation 64 Notch signaling 64 RhoA 64 transgenic mice expressing 64 nicotinic receptor 64 calcineurin 64 TNFR1 64 Wnt signaling 64 VEGF receptor 64 ERa 64 piRNAs 64 HEK# cells 64 Nedd4 64 Th2 64 CD4 + CD# 64 deacetylation 64 adhesion molecule 64 glutamate receptors 64 RNA molecules 64 osteoblast 64 intestinal epithelial cells 64 cathepsins 64 transfected cells 64 interleukins 64 receptor gamma 64 muscarinic receptors 64 GRP# 64 protein encoded 64 oncoproteins 64 SOD1 protein 64 circadian genes 64 overexpressed 64 receptor tyrosine kinase 64 amino acid substitutions 64 cytokine 64 methyltransferases 64 immunoreactivity 64 chloroplast 64 dynamin 64 intracellular signaling 64 WT1 64 tumor antigen 64 HOTAIR 64 overexpressing cells 64 biogenesis 64 NFκB 64 TGF β1 64 GTPases 64 beta globin 64 miR #b [001] 64 astrocytic 64 estrogen receptor beta 64 binding proteins 64 PU.1 64 hyperactivation 64 NKG2D 64 Jhdm2a 64 tumor suppressor genes 64 intronic 64 Skp2 64 mammalian cells 64 TRAF6 64 PAX5 64 histone acetylation 64 EZH2 64 Dpp 64 hypermethylation 64 methylation patterns 64 nucleolar 64 PGE2 64 proapoptotic 64 claudin 64 downregulate 64 gene polymorphisms 64 valine 64 oligomerization 64 ER alpha 64 oncogenic 64 Activating mutations 64 Clusterin 64 TGF alpha 64 synthases 64 inhibitory effects 64 Sox2 64 integrin 64 transferrin receptor 64 phosphatidylinositol 64 non coding RNA 64 ganglioside 64 sequence homology 64 metabolizing enzymes 64 ribosomal protein 64 postsynaptic 64 beta actin 64 plasma membrane 64 GlcNAc 64 oncogenes 64 signaling molecules 64 annexin V 64 ERBB2 64 condensin 64 endogenous ligand 63 glycolipids 63 transferase 63 TGF beta1 63 FGF# 63 mesenchymal cells 63 Sp1 63 β1 63 TNFR 63 protein kinase 63 MT1 MMP 63 loci 63 tRNA synthetase 63 nucleotide 63 FKBP# 63 interneurons 63 NF κB 63 miR# 63 coexpression 63 hepatocyte 63 MyD# 63 intron 63 tyrosine kinase 63 monocyte 63 enolase 63 evolutionarily conserved 63 cardiac fibroblasts 63 phosphatidylinositol 3 63 MEK1 63 var genes 63 synaptogenesis 63 Tregs 63 cyclin dependent kinase inhibitor 63 isomers 63 alveolar epithelial cells 63 IL 1ß 63 activating mutations 63 extracellular domain 63 ubiquitylation 63 polyamine 63 IFN γ 63 ciliated 63 prostaglandin E 63 protein tyrosine kinase 63 RASSF1A 63 microglial activation 63 microRNAs 63 heterozygotes 63 occludin 63 retinoic acid receptor 63 XBP1 63 LNCaP cells 63 transcriptional regulators 63 induced apoptosis 63 peroxidase 63 thymocyte 63 Rab# 63 binding affinity 63 HMG CoA reductase 63 tetramers 63 Pol IV 63 VEGFR1 63 TLR4 63 glioma cells 63 ligand receptor 63 Cx# [001] 63 Overexpression 63 epigenetic mechanisms 63 CEACAM1 63 glycosylation 63 endocytic 63 serine 63 Huntingtin 63 non coding RNAs 63 subtypes 63 FLT3 63 μM 63 short hairpin RNAs 63 fibronectin 63 prolyl 63 anterior pituitary 63 HIF 1a 63 downregulation 63 pro angiogenic 63 PI3K Akt 63 actin binding 63 oncoprotein 63 dimers 63 ERK signaling 63 receptor signaling 63 ATPase 63 kinases 63 cysteine protease 63 HDAC 63 receptor subunit 63 knockout mice 63 HDAC2 63 cysteines 63 cystic fibrosis transmembrane conductance 63 NKT cells 63 microRNA molecules 63 RRM1 63 #ß 63 cytokine secretion 63 DNA polymerases 63 homologue 63 AMPA receptors 63 PKC isoforms 63 transmembrane domains 63 glucocorticoid 63 miRNA molecules 63 IL #p# 63 cytokines IL 63 glioblastoma cells 63 TERT 63 miRNA genes 63 VEGFR2 63 CTCF 63 MEFs 63 Rac1 63 autophagic 63 exons 63 proteoglycan 63 coding sequences 63 beta catenin 63 EGF receptor 63 NKX#.# 63 p# MAPK 63 P2X 63 chaperone proteins 63 lymphoid 63 plasminogen 63 amino terminal 63 PTPN# 63 regulates gene expression 63 triphosphate 63 microglial 63 At#g# 63 semaphorin 63 adipocyte 63 c Fos 63 BMAL1 63 autocrine 63 major histocompatibility complex 63 dimeric 63 mediated inhibition 63 amino acid sequence 63 inhibitory effect 63 peroxisome proliferator activated 63 COL#A# 63 ubiquitin ligase 63 endosomal 63 S. cerevisiae 63 lymphocyte activation 63 lysine residues 63 clades 63 C1q 63 FOXO 63 Upregulation 63 1α 63 leptin receptors 63 Wnt 63 acyl CoA 62 transgenic mice 62 selective antagonists 62 cytokine IL 62 tumor suppressor protein 62 signaling pathway 62 granule cells 62 ubiquitination 62 PPAR gamma 62 orthologous 62 CFTR 62 microRNAs miRNAs 62 selective inhibitors 62 PI3 kinase 62 unmethylated 62 induce apoptosis 62 ncRNA 62 myocyte enhancer factor 62 p#NTR 62 N cadherin 62 matrix metalloproteinases 62 chemokine 62 phosphoprotein 62 Fig. 1C 62 RNA polymerases 62 TNFa 62 endothelial cell 62 epitope 62 caspases 62 Rad# 62 microRNAs miR 62 PPARγ 62 defensin 62 immunodominant 62 cofilin 62 isomerase 62 differentially regulated 62 CD# + [001] 62 heterochromatic 62 Th1 62 acyltransferase 62 alpha subunit 62 Runx2 62 CaM 62 vacuolar 62 wildtype 62 TSP1 62 NF kappaB 62 IL #R 62 alanine 62 cellular organelles 62 IGFBP 3 62 CCR2 62 nucleotide sequence 62 nNOS 62 5 HT1A 62 PPARg 62 C EBP 62 kinase domain 62 miR #b [002] 62 cotransporter 62 oligomeric 62 homolog 62 hepatoma 62 genotypes 62 erythrocytes 62 gene rearrangements 62 signaling molecule 62 short hairpin RNA 62 RUNX3 62 superoxide dismutase 62 p# p# 62 chromosomal regions 62 CDK4 62 carcinoembryonic antigen 62 5 lipoxygenase 62 beta globin gene 62 goblet cells 62 thyroid hormone receptor 62 FUS1 62 serotonin transporter 62 noncoding RNA 62 neuronal differentiation 62 β cells 62 TLRs 62 Flt3 62 Mcl 1 62 DNA demethylation 62 apical membrane 62 p# activation 62 splice variant 62 IRE1 62 ERK pathway 62 MAP kinase 62 inhibitory 62 UCP2 62 caveolae 62 FAK 62 neurones 62 GSK 3ß 62 somatic mutations 62 Kinesin 62 cis 62 ubiquitinated 62 outer membrane proteins 62 TGFb 62 3' UTR 62 #S rRNA 62 6S RNA 62 IFN alpha 62 CD8 + 62 operons 62 VSV G 62 proteolytic cleavage 62 ESR1 62 endogenous 62 cytochrome P# 62 MALAT1 62 carboxyl terminal 62 receptor molecule 62 CXCR4 62 metalloprotease 62 polyadenylation 62 hnRNP 62 tumor suppressor gene 62 GLI1 62 miR #a [002] 62 CD# receptor 62 endogenous ligands 62 fig. S2 62 hydrolase 62 kinase 62 Stat3 62 radial glia 62 Syk 62 IKKß 62 cytokine receptor 62 apoE4 62 presenilin 62 cyclooxygenase COX 62 excitatory synapses 62 costimulatory 62 MDCK cells 62 nAChR 62 Supplemental Figure 62 dehydrogenases 62 AMPA receptor 62 GluR1 62 DISC1 62 methyltransferase 62 T#M 62 regulated kinase 62 Fig. 1A 62 epigenetic silencing 62 HER2 receptors 62 adenylate cyclase 62 GLUT1 62 mammary cells 62 ABCB1 62 p# [001] 62 PC3 cells 62 micro RNA 62 HBx 62 cysteine 62 adhesion molecules 62 phagocytosis 62 LDL receptor 62 nAChRs 62 pyrimidines 62 PTHrP 62 tocopherol 62 Akt1 62 Mice deficient 62 P cadherin 62 tyrosine residues 62 HIF 1α 62 glial 62 lyase 62 binding affinities 62 miRs 62 chemokine receptor 62 TrkB 62 JAK STAT 62 clusterin 62 gene locus 62 signaling cascades 62 Eg5 62 genes 62 TLR2 62 steroidogenic 62 USP# 62 RAR beta 62 pro inflammatory cytokines 62 mucins 62 allelic 62 Bcl XL 62 neoplastic 62 cellular pathways 61 monocyte chemotactic protein 61 CHD5 61 Wnt1 61 bile acid 61 phosphoinositide 61 androgen receptor 61 aminopeptidase 61 dinucleotide 61 HLA DR 61 neutralizing antibody 61 deletion mutant 61 acetylcholine receptor 61 mutant allele 61 alpha Gal 61 podocytes 61 MiRNAs 61 FGF2 61 ZNF# 61 immunostaining 61 fig. S1 61 DARPP 61 virulence factors 61 potent inhibitor 61 dephosphorylation 61 SGK1 61 histone deacetylases 61 μ opioid receptor 61 RANTES 61 A. thaliana 61 TrkA 61 membrane proximal 61 annexin 61 pyrimidine 61 EGFRvIII 61 inflammatory cytokines 61 adrenal cortex 61 glycosyltransferase 61 c Myc 61 differentially expressed genes 61 motoneurons 61 mutant SOD1 61 gp# [002] 61 anti apoptotic proteins 61 kDa 61 MnSOD 61 TRPV3 61 centrosome 61 constitutively activated 61 cAMP signaling 61 c KIT 61 NMDA receptor 61 costimulation 61 PPARgamma 61 Sertoli cell 61 WNK1 61 ChR2 61 neuropeptides 61 cytokine signaling 61 myeloid cells 61 β catenin 61 Drosha 61 allelic variants 61 homologous 61 peptide 61 F actin 61 Neuregulin 1 61 NFAT 61 serotonin receptors 61 SMAD4 61 antigenic epitopes 61 eIF4E 61 PKM2 61 acinar 61 decarboxylase 61 PTEN gene 61 NR2B 61 Wnts 61 polycystin 61 tubulin 61 Transgenic Mice 61 oxidative phosphorylation 61 oxidase 61 paracrine 61 OCT4 61 astrocytes 61 downstream effectors 61 homozygosity 61 gamma secretase 61 potent inhibition 61 amino acid residue 61 glia 61 cyclooxygenase 61 Rho GTPases 61 neurotrophin 61 thymidine 61 Oct4 61 miRNAs miR 61 cytochrome P 61 kD 61 Treg cells 61 IgG1 61 p# mitogen activated 61 neuroligins 61 effector cells 61 apoptotic cells 61 db db mice 61 ErbB4 61 C. elegans 61 CTGF 61 tumor suppressors 61 receptor CD# 61 epithelial 61 cell signaling pathways 61 IDH2 61 Macrophage 61 adipokines 61 guanosine 61 PHD2 61 GABA receptor 61 TNF α 61 mutant protein 61 metalloproteases 61 dopaminergic neurons 61 mesothelin 61 Sgk1 61 isoleucine 61 oligosaccharide 61 HDAC6 61 immunoregulatory 61 cytoplasmic tail 61 glyceraldehyde 3 61 p# NTR 61 tyrosine hydroxylase 61 mutational status 61 costimulatory molecules 61 overactivation 61 proinflammatory cytokines 61 epitopes 61 mitochondrial gene 61 rs# [004] 61 nestin 61 epithelial cells lining 61 soluble proteins 61 cytokeratin 61 COX2 61 monocytes macrophages 61 chaperone protein 61 neural cells 61 steroidogenesis 61 H#K# [001] 61 hypoxia inducible factor 61 striatal 61 kDa protein 61 transporter proteins 61 epithelial cell 61 transmembrane receptor 61 granzyme B 61 Arp2 3 61 mutant alleles 61 4E BP1 61 cytosol 61 posttranslational modifications 61 soluble fms 61 esterase 61 COOH terminal 61 actin cytoskeleton 61 apoptotic pathway 61 anti apoptotic 61 UTRs 61 keratinocyte 61 Nup# 61 adrenoceptor 61 ligases 61 Bcl 61 transgene 61 insulin receptors 61 catalytic subunit 61 progranulin 61 aggrecan 61 histone H4 61 centromeres 61 CYP#B# 61 NR2B subunit 61 Cdx2 61 PDE#A 61 ERalpha 61 plastids 61 c fos 61 substituents 61 centrioles 61 CpG 61 auxin 61 antiapoptotic 61 GPR# [001] 61 sphingolipid 61 hematopoietic cells 61 CCL# 61 Saccharomyces cerevisiae 61 BACE1 61 NF kB 61 connexin# 61 DLX5 61 sensory neurons 61 CDKs 61 GABAergic 61 JNK1 61 overexpress 61 alpha2 61 sortilin 61 EGFR 61 D2 receptors 61 cytotoxicity 61 Cathepsin B 61 fusion proteins 61 RCAN1 61 dystroglycan 61 Wnt#b 61 FGFR1 61 trophoblast cells 61 acetyl CoA 61 PIP2 61 apoptotic