Related by context. All words. (Click for frequent words.) 73 renal insufficiency 73 left ventricular systolic 73 renal dysfunction 73 myocardial ischemia 73 left ventricular hypertrophy 73 β blockers 72 systolic dysfunction 71 thromboembolic events 71 hypoperfusion 71 LV dysfunction 71 paroxysmal AF 71 renal artery stenosis 70 silent ischemia 70 periprocedural 70 preserved ejection fraction 70 occlusive disease 70 cerebral ischemia 70 revascularization procedures 70 reinfarction 70 myocardial infarction 70 myocardial infarction MI 70 thromboembolic 70 LVSD 69 carotid stenosis 69 systolic hypertension 69 microvascular disease 69 postoperative complication 69 hypercalcemia 69 paclitaxel eluting stents 69 rhythm disturbances 69 β blocker 69 ventricular arrhythmia 69 postoperative AF 69 thyrotoxicosis 69 unstable angina pectoris 69 multivessel disease 69 torsades de pointes 69 thrombotic events 69 nonischemic 69 hyperkalemia 68 stenoses 68 dysfunction LVSD 68 infarctions 68 cardiac dysfunction 68 ATACAND 68 coronary revascularization 68 intracerebral hemorrhage 68 cerebral infarction 68 atrioventricular block 68 ventricular fibrillation VF 68 aminotransferases 68 macrovascular disease 68 airflow obstruction 68 angina pectoris 68 subclinical hypothyroidism 68 renal impairment 68 colorectal adenoma 68 ischemic cardiomyopathy 68 thromboembolic complications 68 aortic regurgitation 68 acute myocardial infarction AMI 68 proliferative diabetic retinopathy 68 upper gastrointestinal bleeding 68 hypoxemia 68 eplerenone 68 pericardial effusion 68 cardiogenic shock 68 recurrent ischemia 67 cerebrovascular events 67 aortic valve stenosis 67 mitral stenosis 67 mitral insufficiency 67 cerebral vasospasm 67 thromboembolism 67 prolonged QT interval 67 diastolic heart 67 inotropic agents 67 myocardial infarct 67 cTnT 67 NYHA class 67 arteriography 67 hyperglycaemia 67 decompensated heart failure 67 perioperative complications 67 cytopenias 67 UA NSTEMI 67 nonfatal MI 67 QTc interval 67 tirofiban 67 ejection fractions 67 postoperative morbidity 67 angioplasty stenting 67 pneumonectomy 67 valvular disease 67 stable angina 67 dobutamine 67 bypass grafting 67 antihypertensive therapy 67 extrapyramidal symptoms 67 CK MB 67 thrombotic complications 67 CABG surgery 67 diastolic dysfunction 67 detrusor overactivity 67 inotropic 66 adrenal insufficiency 66 hypokalemia 66 non valvular atrial 66 undergoing coronary artery 66 jugular venous 66 macroalbuminuria 66 VAPRISOL 66 microbleeds 66 infarcts 66 malperfusion 66 MACCE 66 coronary stenosis 66 recurrent VTE 66 Erythropoietic therapies may 66 asymptomatic carotid stenosis 66 paroxysmal atrial fibrillation 66 hemodynamic instability 66 revascularisation 66 nicardipine 66 carotid intima media 66 echocardiographic 66 stenosis 66 torsade de pointes 66 carotid artery blockage 66 pseudoaneurysm 66 pulmonary artery banding 66 angina chest 66 coronary artery disease 66 ischemic stroke 66 alteplase 66 loop diuretics 66 nephrotoxicity 66 lung resection 66 angiotensin converting enzyme inhibitor 66 NYHA Class II 66 ventricular arrhythmias 66 tolvaptan 66 artery stenosis 66 hyperalgesia 66 macrovascular 66 perioperative mortality 66 thrombus aspiration 66 atrioventricular valve 66 esophageal perforation 66 hemorrhagic complications 66 transthoracic 66 atherosclerotic disease 66 ventricular dysfunction 66 albuminuria 65 tricuspid regurgitation 65 severe hypoglycemia 65 beta blocker therapy 65 oral antidiabetic medication 65 overt nephropathy 65 atherosclerotic lesions 65 Hypotension 65 hypercholesterolaemia 65 rebleeding 65 myocardial infarction stroke 65 incomplete revascularization 65 hyperprolactinemia 65 revascularization procedure 65 Pulmonary hypertension 65 myopathy rhabdomyolysis 65 LVEF 65 Thrombolysis 65 carotid atherosclerosis 65 tumor lysis syndrome 65 coronary stenoses 65 fibrinolytic therapy 65 acute myocardial infarction 65 left ventricular ejection 65 serum creatinine levels 65 stent implantation 65 mitral regurgitation 65 acute myocardial infarction MI 65 hypoglycemic events 65 ischemic complications 65 detrusor 65 hematuria 65 CIMZIA ™ 65 denervation 65 tachyarrhythmias 65 left ventricular LV 65 coronary blockages 65 ventricular dilatation 65 fibrinolysis 65 postoperative mortality 65 coagulopathy 65 septal defects 65 carotid IMT 65 reperfusion therapy 65 transaminase elevations 65 coronary intervention 65 cardiac tamponade 65 stenotic 65 microvascular complications 65 sinus bradycardia 65 acute decompensation 65 Torsades de Pointes 65 electrical cardioversion 65 thrombolytic therapy 65 venous thrombosis 65 cerebrovascular accident 65 intracoronary 65 glycated hemoglobin levels 65 cardioembolic stroke 65 thrombophlebitis 65 subtrochanteric 65 troponin T 65 primary aldosteronism 65 OPCAB 65 systemic embolism 65 elevated triglyceride levels 65 RVOT 65 ischaemia 65 nondiabetic patients 65 sinus node dysfunction 65 rFVIIa 65 QT prolongation 65 coronary calcification 65 CTEPH 65 QRS duration 65 QTc prolongation 65 NSTEMI 65 atrophic gastritis 64 candesartan 64 postoperative pulmonary 64 primary percutaneous coronary 64 cardiac insufficiency 64 Mitral regurgitation 64 infarct size 64 conventional angiography 64 carotid artery stenosis 64 morphometric vertebral fractures 64 TEAEs 64 afterload 64 platelet reactivity 64 typical antipsychotics 64 aspartate aminotransferase AST 64 hypocalcemia 64 T2DM 64 hyperacute 64 dyssynchrony 64 fatal myocardial infarction 64 esophageal varices 64 TNF antagonist 64 onset atrial fibrillation 64 antiarrhythmic drug 64 ventricular tachyarrhythmia 64 CYP #A# 64 PAOD 64 impaired renal 64 acutely decompensated congestive heart 64 cryptogenic stroke 64 corticosteroid therapy 64 delayed gastric emptying 64 contrast induced nephropathy 64 recurrent atrial fibrillation 64 aspirin clopidogrel 64 aortic arch 64 coronary artery bypass grafting 64 leiomyomas 64 undergoing CABG 64 DAPT 64 hypotension 64 reoperations 64 adrenalectomy 64 noncardiac 64 ventricular septal defects 64 variceal bleeding 64 thrombocytopenic 64 angiotensin converting enzyme inhibitors 64 QT intervals 64 myocardial infarctions 64 microalbuminuria 64 induce orthostatic hypotension 64 sinus tachycardia 64 estimated glomerular filtration 64 APTIVUS r 64 coronary artery stenosis 64 amenorrhoea 64 postoperative delirium 64 ventricular tachycardia VT 64 lipid lowering therapy 64 BYSTOLIC 64 vasospasm 64 thrombus formation 64 superficial femoral 64 hypoglycemic episodes 64 angiotensin II receptor blockers 64 COREG 64 VIIBRYD 64 arterial calcification 64 intraventricular 64 systemic hypotension 64 revascularization 64 candesartan cilexetil 64 arterial thromboembolic events 64 platelet inhibition 64 mitral regurgitation MR 64 plasminogen activators 64 postoperative complications 64 neointimal hyperplasia 64 QTc 64 valvular 64 cardiovascular mortality 64 Eisenmenger syndrome 64 chronic thromboembolic pulmonary 64 distensibility 64 symptomatic intracranial 64 interstitial pneumonia 64 pericardial effusions 64 systemic corticosteroids 64 DMARD 64 percutaneous intervention 64 inotropes 64 abciximab 64 HIV HCV coinfected 64 tenecteplase 64 arrhythmias 64 thyrotropin levels 64 cardiomegaly 64 systemic corticosteroid 64 intima media thickness 64 hepatotoxicity 64 resynchronization therapy 64 paricalcitol 64 milrinone 64 bradycardia 64 hepatic failure 64 ropivacaine 64 ischemia driven 64 perfusion defects 64 elevated ALT 64 hypercalcaemia 64 salmeterol HFA MDI 63 serum phosphate 63 antiarrhythmic drugs 63 post thrombotic syndrome 63 intracranial hemorrhage ICH 63 aldosterone antagonists 63 nonobstructive CAD 63 angiographically 63 pulmonary resection 63 aortic insufficiency 63 reintervention 63 varices 63 GnRH agonist 63 mixed hyperlipidemia 63 bronchial hyperresponsiveness 63 dosage regimens 63 eptifibatide 63 pseudoaneurysms 63 cardiovascular hospitalizations 63 hERG channel 63 posttransplant 63 gouty arthritis 63 PSA nadir 63 NATRECOR ® 63 coronary angiography 63 intrahepatic 63 antiplatelet drugs 63 mechanical dyssynchrony 63 drug eluting stent implantation 63 hyperparathyroidism 63 reflux symptoms 63 intravenous bisphosphonates 63 metabolic acidosis 63 receiving VELCADE 63 Intracranial 63 claudication 63 deep vein thromboses 63 neurologic deficits 63 fibrinolytic 63 serum calcium levels 63 stent placement 63 gastrointestinal perforation 63 Stent thrombosis 63 severe exacerbations 63 generalized tonic clonic seizures 63 hemodilution 63 abnormal uterine bleeding 63 calcified plaques 63 antithrombotic therapy 63 parathyroidectomy 63 coronary disease 63 thrombolytic agents 63 elevated triglycerides 63 lactic acidosis 63 Prehypertension 63 repolarization 63 calculi 63 ventricular remodeling 63 vertebral fracture 63 glomerular filtration rate 63 EXJADE 63 nonfatal stroke 63 nonfatal myocardial infarction 63 unstable angina UA 63 transesophageal echocardiography 63 valvular heart disease 63 plasma creatinine 63 hemodynamics 63 severe renal impairment 63 cardiac conduction 63 colorectal liver metastases 63 ventricular dyssynchrony 63 antihypertensive medications 63 valve regurgitation 63 femoral neck fracture 63 surgical revascularization 63 Tasigna prolongs 63 elevated CRP 63 pheochromocytoma 63 pulmonary arterial 63 QT interval prolongation 63 glomerular filtration 63 cirrhotic 63 systolic function 63 primidone 63 serum phosphorous 63 deep venous thromboses 63 serum uric acid 63 mL/min/#.# m 2 63 postoperative atrial fibrillation 63 ipsilateral stroke 63 aortic stenosis 63 patients undergoing CABG 63 proliferative retinopathy 63 valve implantation 63 thromboses 63 thromboprophylaxis 63 cardiac toxicity 63 endoleaks 63 sotalol 63 cytoreductive surgery 63 transurethral resection 63 onset diabetes mellitus 63 atrial fibrillation AF 63 atherothrombosis 63 dopaminergic therapy 63 cardiac resynchronization 63 QTc intervals 63 fluid overload 63 postoperative hemorrhage 63 MGUS 63 outflow tract 63 intracerebral 63 Mitral valve 63 percutaneous transluminal coronary angioplasty 63 intravesical therapy 63 balloon valvuloplasty 63 infarction STEMI 63 arterial occlusion 63 ICD shocks 63 cardiopulmonary bypass CPB 63 hepatocellular 63 INTEGRILIN R 63 progressive dyspnea 63 noncardiac surgery 63 acute coronary syndromes 63 arrhythmogenic 63 extubation 63 parenchymal 63 syncope 63 obstructive CAD 63 cerebral perfusion 63 PRADAXA #mg 63 electrolyte abnormalities 63 perioperatively 63 NYHA Class III 63 bezafibrate 63 aortic root replacement 62 severe mitral regurgitation 62 intravitreal injections 62 Thal Dex 62 endometrial hyperplasia 62 neurologic complications 62 perioperative morbidity 62 Pegylated Liposomal Doxorubicin 62 acetabular dysplasia 62 androgen deprivation 62 anticoagulation therapy 62 airway narrowing 62 Coronary Artery Bypass Graft 62 arterial thrombosis 62 isolated systolic hypertension 62 cholecystitis 62 benazepril 62 myocardial perfusion 62 LV ejection fraction 62 refractory ischemia 62 elevated LDL cholesterol 62 vasodilators 62 arteriolar 62 patients undergoing percutaneous 62 vessel occlusion 62 ICD implantation 62 nephropathy 62 generalized seizures 62 septal 62 percutaneous interventions 62 ß blockers 62 chest radiographs 62 liver metastasis 62 cardiopulmonary bypass 62 pulmonary vasculature 62 ventricular tachycardia 62 aldosterone antagonist 62 heart arrhythmias 62 intracranial atherosclerosis 62 silent myocardial ischemia 62 recombinant tissue plasminogen 62 NATRECOR R 62 irbesartan 62 cilostazol 62 acute myocardial infarctions 62 arrythmias 62 pathologic fractures 62 Duodenal 62 infarction NSTEMI 62 pleural effusions 62 infarction 62 chronic pancreatitis 62 paroxysmal supraventricular tachycardia 62 atrioventricular 62 hypothermic circulatory arrest 62 hemodynamically 62 coronary insufficiency 62 ischemia 62 serum urate levels 62 acute aortic dissection 62 HbA1c levels 62 intraoperative complications 62 orthostatic hypotension 62 Postoperative complications 62 hepatic metastases 62 venous reflux 62 haemorrhagic stroke 62 anticholinergic medications 62 chloride secretion 62 lipid lowering drugs 62 impaired hepatic 62 atherothrombotic disease 62 repeat revascularization 62 MULTAQ 62 selective cerebral perfusion 62 autonomic dysfunction 62 edifoligide 62 serum creatinine 62 angiotensin receptor blockers ARBs 62 dysuria 62 ULORIC 62 carcinoids 62 hypoglycaemic episodes 62 tHcy 62 comorbid conditions 62 mediastinum 62 LMWH 62 olmesartan 62 asystole 62 comorbidities 62 infective endocarditis 62 acute hepatic 62 crossclamp 62 adenomatous 62 revascularizations 62 benign prostate 62 ischemic 62 proximal DVT 62 alpha blocker 62 antithrombotic 62 cirrhotic patients 62 Postoperative 62 prostate TURP 62 cTnI 62 intravenous diuretics 62 arteriovenous access 62 transaminases 62 secondary hyperparathyroidism 62 peri procedural 62 HMG CoA reductase inhibitors 62 basal cell nevus syndrome 62 preserved systolic 62 cytopenia 62 ventricular dilation 62 PLX STROKE targeting 62 ivabradine 62 methotrexate therapy 62 hepatic function 62 neurologic symptoms 62 angiotensin receptor blockers 62 subclinical atherosclerosis 62 ribavirin therapy 62 acute coronary syndrome 62 esophagogastric 62 akinesia 62 anastomotic leak 62 AV fistulas 62 retransplantation 62 atrial arrhythmias 62 serum potassium 62 cerebrovascular accidents 62 ileus 62 warfarin therapy 62 airflow limitation 62 corrected QT interval 62 pulmonary exacerbation 62 acromegalic patients 62 narrowings 62 oral hypoglycemic agents 62 verapamil 62 pulmonary infiltrates 62 thrombolytics 62 metformin monotherapy 62 transcatheter closure 62 urethral strictures 62 hypokalemia hypomagnesemia 62 bosentan 62 isoproterenol 62 moderate renal impairment 62 cystic lesions 62 sustained ventricular tachycardia 62 NIHSS score 62 aneurysmal subarachnoid hemorrhage 62 cardiac troponin 62 atherothrombotic events 62 vasopressor 62 myocardial contractility 62 vertebrobasilar 62 Aortic valve 62 VADT 62 hydrops 62 aminotransferase levels 62 VT VF 62 flecainide 62 stroke transient ischemic 62 diastolic hypertension 62 Ventricular Tachycardia 62 ALT flares 62 pathologic fracture 62 intracranial stenosis 62 irregular quivering 62 surgically induced 62 platelet activation 62 severe hypersensitivity reactions 62 elevated serum creatinine 62 tricuspid 62 sirolimus eluting stents 62 carotid plaque 62 inhaled budesonide 62 paragangliomas 62 esophagitis 62 haemodynamic 62 hemodynamically significant 62 hyperglycemia 62 cerebral angiography 62 unknown etiology 62 normotensive 62 osteochondroma 62 Candesartan 62 concomitant medications 62 intact parathyroid hormone 62 embolic stroke 62 hematologic toxicity 62 cystectomy 62 serum phosphate levels 62 Lp PLA2 62 elevated creatinine 62 pacemaker implantation 62 endoleak 62 NMIBC 62 intravenous cyclophosphamide 61 hamartomas 61 left ventricular diastolic 61 gastroduodenal 61 biventricular pacing 61 pulmonary capillary wedge 61 ventricular myocardium 61 ventricular RV 61 GISTs 61 macrovascular events 61 nadolol 61 recanalization 61 reinterventions 61 arteriovenous fistula 61 baroreflex 61 tachycardias 61 radiotherapy RT 61 hypercalciuria 61 cardiac repolarization 61 PREZISTA r 61 hepatic cirrhosis 61 liver transaminases 61 prostate carcinoma 61 nonrandomized 61 proteinuria 61 arterial hypertension 61 anthracycline therapy 61 artery occlusion 61 creatine kinase MB 61 tachyarrhythmia 61 sirolimus stent 61 intermittent claudication 61 Asymptomatic 61 hypotensive 61 familial hypercholesterolemia 61 binary restenosis 61 hepatectomy 61 hemodynamic parameters 61 XIENCE V PROMUS Stent 61 baroreflex sensitivity 61 GnRH agonists 61 ADPKD 61 nesiritide 61 thiazide diuretics 61 anticoagulant therapy 61 oral anticoagulation 61 lipid lowering agents 61 coronary artery revascularization 61 dronedarone 61 coronary artery bypass grafts 61 EEG abnormalities 61 patent foramen ovale 61 ADHF 61 plasma uric acid 61 lipid abnormalities 61 Aortic stenosis 61 hypercholesterolemic patients 61 NSAID therapy 61 ximelagatran 61 ventricular function 61 glycoprotein IIb IIIa inhibitors 61 DMARD therapy 61 serum urate 61 atrial fibrillation 61 undergoing coronary angiography 61 thoracoscopic lobectomy 61 biliary tree 61 Fontan procedure 61 thrombolysis 61 Renal dysfunction 61 diastolic function 61 thyroidectomy 61 occlusions 61 IIIa inhibitor 61 sinus rhythm 61 antiarrhythmic 61 lacunar 61 colorectal adenomas 61 hypopneas 61 lipid lowering therapies 61 Severe hypoglycemia 61 ischemic mitral regurgitation 61 myocardial fibrosis 61 endarterectomy 61 LV systolic dysfunction 61 intra arterial 61 mitral valve regurgitation 61 T1DM 61 diabetes mellitus DM 61 hypovolemia 61 nonoperative treatment 61 saphenous vein grafts 61 POAG 61 catheter angiography 61 asthma exacerbation 61 nonvertebral fracture 61 biliary obstruction 61 PSADT 61 acute coronary syndromes ACS 61 cervical lymph nodes 61 nonoperative 61 PsA 61 postprocedure 61 laboratory abnormalities 61 cinacalcet 61 ABCB1 61 dorsalis pedis 61 tumor resection 61 hypertensives 61 peptide BNP 61 CVD mortality 61 carotid artery stenting CAS 61 endophthalmitis 61 arterial revascularization 61 cardiovascular hospitalization 61 impaired fasting glucose 61 thrombosis 61 NYHA functional class 61 myocardium 61 serum ALT 61 hypertension diabetes mellitus 61 radicular pain 61 tamsulosin 61 transferrin saturation 61 primary hypercholesterolemia 61 atherogenic dyslipidemia 61 invasive coronary angiography 61 cardioprotection 61 hypophosphatemia 61 Events MACE 61 nasal obstruction 61 pulmonary artery hypertension 61 impaired cognition 61 thrombotic 61 endometrial carcinoma 61 fibrin deposition 61 fluvastatin 61 viable myocardium 61 LV hypertrophy 61 Endothelial dysfunction 61 retinal vein occlusion 61 gastric varices 61 rosuvastatin #mg 61 azacitidine 61 macrovascular complications 61 perindopril 61 gastrointestinal toxicity 61 Ivabradine 61 Vaprisol 61 hypomagnesemia 61 pulmonary dysfunction 61 levodopa therapy 61 glucocorticoid therapy 61 antiplatelet medications 61 virologic failure 61 endobronchial 61 PSVT 61 postoperative chemotherapy 61 amyloid deposition 61 subclinical hyperthyroidism 61 #mm Hg 61 coronary occlusion 61 calcaneal fractures 61 occlusion CRVO 61 hepatic enzyme 61 steatosis 61 haloperidol Haldol 61 thoracic aortic aneurysm 61 ARIXTRA 61 Thrombocytopenia 61 potentially hepatotoxic 61 intracardiac 61 invasive angiography 61 androgen suppression 61 uncontrolled hypertension 61 angioedema 61 pulmonary toxicity 61 pharmacokinetic interactions 61 carotid plaques 61 Doxil ® 61 Acute Myocardial Infarction 61 hypercapnia 61 intracerebral hemorrhage ICH 61 serum calcium 61 depressive symptomatology 61 dysrhythmias 61 Complication rates 61 thiazide diuretic 61 coadministration 61 Dronedarone 61 evaluating CK # 61 alanine aminotransferase ALT 61 clomipramine 61 ST elevation myocardial 61 mild renal insufficiency 61 adenomatous polyps 61 thrombi 61 hypertrophy 61 riociguat 61 Myocardial infarction 61 Taxus Stent 61 fractional shortening 61 Ebstein anomaly 61 vagal 61 Statin therapy 61 pathophysiologic 61 graft occlusion 61 fibrosis scarring 61 nonvertebral fractures 61 pulmonary exacerbations 61 intensive statin therapy 61 ACTOplus met XR 61 Aneurysms 61 peritumoral 61 pulmonary arteries 61 choroidal neovascularization CNV 61 prostate cancer CaP 61 angina 61 vascular dysfunction 61 thickness IMT 61 antiplatelet therapy 61 symptomatic paroxysmal AF 61 pressor response 61 HMG CoA reductase inhibitor 61 symptomatic carotid stenosis 61 severe bronchial asthma 61 venlafaxine Effexor 61 coarctation 61 Cardiopulmonary bypass 61 gout flares 61 metastatic malignant 61 cranial irradiation 61 choroidal neovascularization 61 malignant neoplasm 61 underwent coronary angiography 61 Venous thromboembolism 61 unstable angina 61 OADs 61 parathyroid carcinoma 61 pancytopenia 61 atheroma 61 gross hematuria 61 renal scarring 61 renal cysts 61 mucinous 61 prednisone prednisolone 61 induce regression 61 neuroleptics 61 Pioglitazone 60 radical nephrectomy 60 creatinine clearance 60 ACTOplus met 60 abdominal adiposity 60 cardiomyopathies 60 reflux esophagitis 60 TURP 60 thromboembolic disease 60 SGPT 60 AST ALT 60 TAXUS Express Stent 60 weekly subcutaneous injections 60 functional mitral regurgitation 60 colectomy 60 cardiac biomarkers 60 hypercoagulable 60 gestational hypertension 60 elevated IOP 60 Hashimoto thyroiditis 60 HeFH 60 lichen planus 60 femoral shaft fractures 60 muscarinic receptors 60 hematopoietic cancers 60 Brugada syndrome 60 coronary 60 QT QTc 60 endothelial dysfunction 60 reteplase 60 TACE 60 hypertriglyceridemia 60 cystatin C 60 CrCl 60 onset seizures 60 liver resection 60 QT interval 60 ipsilateral 60 postintervention 60 tamponade 60 stratifying patients 60 carcinoid tumor 60 reperfusion 60 mediastinitis 60 hemorrhagic strokes 60 anticoagulants blood thinners 60 airway hyperresponsiveness 60 Atrial 60 definite stent thrombosis 60 unfractionated heparin 60 diabetes mellitus 60 biochemical recurrence 60 hepatic insufficiency 60 ischemic colitis 60 liver histology 60 ascending aortic 60 atrial enlargement 60 Carvedilol 60 intracerebral haemorrhage 60 CRVO 60 intravesical 60 nonfatal myocardial infarction MI 60 Atacand 60 myocardial 60 pelvic lymphadenectomy 60 intimal hyperplasia 60 IPAH 60 IOP lowering 60 colorectal carcinoma 60 lobectomy 60 NIASPAN 60 acute ischemic stroke 60 cardiovascular morbidity