Related by context. All words. (Click for frequent words.) 78 cholesterol metabolism 77 carbohydrate metabolism 73 lipoprotein metabolism 70 mitochondrial function 70 fatty acid metabolism 69 estrogen metabolism 69 transcriptional regulation 69 glycogen metabolism 68 calcium homeostasis 68 tumorigenesis 68 synapse maturation 68 podocytes 68 signaling pathways 67 synaptic transmission 67 BMP signaling 67 metabolic 67 plasma lipids 67 neuronal differentiation 67 plasma lipid 67 UCP2 67 catabolism 67 glucose homeostasis 67 metabolic pathways 67 dysregulation 66 chromatin structure 66 insulin secretion 66 PPAR gamma 66 sortilin 66 molecular mechanisms underlying 66 lipid homeostasis 66 pathophysiological 66 receptor gamma 66 carcinogenesis 66 fatty acid oxidation 66 proinflammatory 66 hypothalamic 66 neurofibromin 66 pathogenesis 66 cell signaling pathways 66 Notch signaling 66 lipids 66 podocyte 66 peroxisome proliferator activated 66 neuronal signaling 66 SH2 B 66 tyrosine phosphorylation 66 molecular pathways 66 LDL receptor 66 hormone adiponectin 66 Wnt signaling 66 chromatin remodeling 66 Akt 65 PPAR alpha 65 bile acid metabolism 65 ERK signaling 65 regulating gene expression 65 mitogen activated protein kinase 65 signaling pathway 65 SIRT1 65 insulin resistance 65 phosphatidylinositol 3 65 serine proteases 65 adipokines 65 calpain 65 adipokine 65 sphingolipids 65 glucose metabolism 65 axon guidance 65 cholesterol homeostasis 65 NF kappaB pathway 65 synaptic function 65 apoptotic pathway 65 molecular pathway 65 ABCA1 64 atherogenesis 64 NF kappaB 64 folate metabolism 64 cellular pathways 64 apoE 64 epigenetic mechanisms 64 telomere maintenance 64 protein kinase C 64 neurotransmission 64 adipogenesis 64 oxidative phosphorylation 64 gene transcription 64 vascular endothelial 64 metabolism 64 neuroendocrine 64 hypothalamic pituitary adrenal axis 64 bone metabolism 64 HMG CoA reductase 64 synaptic plasticity 64 cell signaling pathway 64 gastric carcinogenesis 64 epigenetic regulation 64 eNOS 64 histone modifications 64 signaling cascades 64 pathophysiological mechanisms 64 molecular mechanism 64 nitric oxide synthase 64 endocannabinoid system 64 SH#B# 64 Smad3 64 caveolin 64 histone deacetylases 64 Aldosterone 64 metabolizing enzymes 64 DISC1 64 SREBP 64 autophagic 64 neuronal plasticity 64 tumor suppressor protein 64 RUNX3 64 prostate carcinogenesis 64 lipoprotein lipase 64 PPARg 64 intestinal microflora 64 metabolic processes 64 extracellular signal 64 metabolic enzymes 64 isoenzymes 64 CaM kinase II 64 HSF1 64 neuronal dysfunction 63 biochemical pathways 63 Angiotensin converting enzyme 63 Hedgehog signaling 63 lipid synthesis 63 LXRs 63 p# MAPK 63 adipogenic 63 neuropeptide Y NPY 63 eicosanoids 63 cellular metabolism 63 motor neuron degeneration 63 TXNIP 63 leptin signaling 63 Phosphorylation 63 biogenesis 63 dystroglycan 63 Oxidative stress 63 systemic inflammation 63 TNFalpha 63 Wnt proteins 63 adipocyte 63 lipid 63 PPARγ 63 signal transduction 63 hyperinsulinemia 63 apoE4 63 receptor subtypes 63 neurite outgrowth 63 biochemical mechanisms 63 Wnt pathway 63 SCD1 63 glycolipids 63 prostaglandin synthesis 63 insulin signaling pathways 63 RBP4 63 drug metabolizing enzymes 63 steroid hormones 63 mRNA expression 63 hematopoiesis 63 ENaC 63 activin 63 neuronal function 63 PPAR γ 63 osteocalcin 63 COX enzymes 63 TMEM#B 63 intracellular signaling 63 FGF2 63 IL6 63 gut microbiota 63 LRP5 63 hypoxia inducible factor 63 enzymatic pathways 63 KLF4 63 PI3K signaling 63 HPA axis 63 malonyl CoA 63 biologic pathways 63 K + ATPase 63 calcineurin 63 Notch pathway 63 tau phosphorylation 62 incretin 62 cell adhesion 62 lipoxygenase 62 TGF β 62 gene expression 62 proteolysis 62 FGFs 62 glutamate receptors 62 intracellular signaling pathways 62 genetic polymorphism 62 GABAA receptors 62 hormone secretion 62 obesity insulin resistance 62 TLR4 62 cardiolipin 62 biochemical pathway 62 CTGF 62 renin angiotensin aldosterone 62 secretory pathway 62 melanocortin 62 signaling molecule 62 LKB1 62 gluconeogenesis 62 pro angiogenic 62 eotaxin 62 tumor suppressor PTEN 62 biosynthesis 62 DNA methylation patterns 62 micro RNAs 62 superoxide dismutase 62 pathophysiology 62 glucocorticoid receptor 62 POMC neurons 62 LIS1 62 dysregulated 62 oxidase 62 resistin 62 FoxO1 62 intracellular proteins 62 MMPs 62 protein kinases 62 γ secretase 62 PON1 62 COX2 62 actin cytoskeleton 62 proapoptotic 62 ERK1 2 62 airway remodeling 62 Dysregulation 62 hormones leptin 62 synaptogenesis 62 synapse formation 62 Sirt1 62 PTPN# 62 pre mRNA splicing 62 protein synthesis 62 triglyceride metabolism 62 neurodegeneration 62 IL 1β 62 colorectal carcinogenesis 62 amylin 62 TCF#L# 62 lipid levels 62 gene polymorphisms 62 SGLT1 62 FOXO 62 autocrine 62 PDGFR 62 mitochondrial biogenesis 62 mitochondrial dysfunction 62 oncogenesis 62 cofactors 62 endocannabinoid signaling 62 casein kinase 62 cholesterol efflux 62 endothelial dysfunction 62 intestinal epithelium 62 immunomodulatory effects 62 Wnt signaling pathway 62 cAMP signaling 62 lipid rafts 62 UCP1 62 collagen synthesis 62 Sirt3 62 endothelial nitric oxide synthase 62 AT1R 62 Proteostasis Network 62 biochemical processes 62 plasma lipid profiles 62 fibrogenesis 62 potent inhibitors 62 MAPK 62 calcium calmodulin dependent 62 blood lipids 62 VE cadherin 62 intracellular signal transduction 62 mTOR 62 metabolic disturbances 62 regulated kinase ERK 62 neurohormonal 62 lymphocyte activation 62 oxidases 61 glucose tolerance 61 Thyroid hormone 61 HCV replication 61 hepcidin 61 CEACAM1 61 retinoid X 61 cystic fibrosis transmembrane conductance 61 enzyme cofactor 61 adult neurogenesis 61 glutamatergic 61 muscarinic receptors 61 melanocortin receptors 61 methylation patterns 61 cytoskeletal 61 palmitate 61 improves insulin sensitivity 61 antioxidative 61 TSP1 61 orexin 61 adiponectin 61 insulin sensitivity 61 SIRT2 61 glucose transporter 61 phosphorylates 61 Wnts 61 protein phosphorylation 61 genetic polymorphisms 61 β catenin 61 EGFR signaling 61 neuropeptide Y 61 ACh 61 RANK ligand 61 selective inhibition 61 NMDA receptors 61 cytokine 61 histone acetylation 61 osteoclast formation 61 glucose uptake 61 D aspartic acid 61 XBP1 61 phospholipase A2 61 cypin 61 p# activation 61 presenilin 61 retinol binding protein 61 renal fibrosis 61 Lp PLA 2 61 serine protease 61 mitochondrial metabolism 61 RIP1 61 neuronal degeneration 61 paxillin 61 tumor microenvironment 61 physiological mechanisms 61 TORC2 61 PDE5A 61 acetylcholine receptor 61 fatty acid synthase 61 insulin receptors 61 cyclooxygenase 2 61 leptin receptor 61 serotonin receptor 61 neurocircuitry 61 osteoblast 61 oxidized LDL 61 mTORC1 61 cholesterol biosynthesis 61 hypothalamic pituitary 61 peroxisomal 61 ERK pathway 61 ubiquitylation 61 serotonin signaling 61 chitinase 61 p# pathway 61 intestinal microbiota 61 polyamine 61 epigenetic alterations 61 plasma kallikrein 61 mTOR signaling 61 modulatory 61 innate immunity 61 Hh pathway 61 encodes protein 61 histone modification 61 p#/CBP 61 hedgehog signaling 61 CHD7 61 JNK1 61 GluR1 61 cell adhesion molecule 61 erythropoiesis 61 mediated inhibition 61 glucagon secretion 61 proto oncogene 61 neuroinflammation 61 ABCB1 61 Kv#.# 61 Galectin 3 61 stem cell differentiation 61 polyamines 61 PGC 1α 61 proinflammatory cytokine 61 FOXO3a 61 triacylglycerol 61 dietary fats 61 antioxidant enzyme 61 downregulation 61 histone methylation 61 protein tyrosine kinase 61 eicosanoid 61 tumor angiogenesis 61 NR2B 61 hepatic glucose production 61 c myc gene 61 glycosylation 61 endothelial function 61 mitochondrial oxidative 61 osteoblast differentiation 61 intracellular pathways 61 GCN2 61 GABA neurotransmitter 61 acetylation 61 muscle contractility 61 Clusterin 61 NRF2 gene 61 chromatin remodeling complex 61 TGF ß 61 remnant lipoproteins 61 heparan sulfate 61 Vascular endothelial growth 61 transcription factors 61 overactivation 60 downstream effector 60 non coding RNA 60 dietary fatty acids 60 PEDF 60 GRP# 60 Rab5 60 estrogen receptor alpha 60 ALDH2 60 cytochrome P# 60 mitochondrial respiration 60 TGF b 60 hypocretin 60 FGF# 60 aldosterone 60 inducible nitric oxide synthase 60 NMDA receptor 60 Genetic variants 60 MAP kinases 60 progranulin 60 glucokinase 60 dopaminergic 60 S1P 60 platelet activation 60 gut microflora 60 Nrf2 60 endothelial activation 60 spermidine 60 Apolipoprotein E 60 PP2A 60 cystic fibrosis transmembrane 60 glucocorticoid receptor GR 60 incretins 60 VIPR2 60 lipogenesis 60 NF kB signaling 60 S#A# [002] 60 Nedd4 60 interleukin 1beta 60 cardiometabolic disorders 60 membrane lipids 60 pleiotropic effects 60 hepatic lipase 60 MAP kinase pathway 60 thyroid hormones 60 HIF 1alpha 60 PI3K pathway 60 receptor subtype 60 molecular signaling pathway 60 transcriptional activation 60 NFAT 60 insulin signaling pathway 60 serine threonine kinase 60 regulates gene expression 60 inhibitory neurotransmitters 60 ACE2 60 nNOS 60 endocrine glands 60 melatonin receptor 60 GLI1 60 CB2 receptor 60 Hypoxia Inducible Factor 60 tumor metastasis 60 PDE#A 60 factor BDNF 60 hyperphosphorylation 60 Angiotensin II 60 lysosomal 60 mutant huntingtin protein 60 Sgk1 60 axon outgrowth 60 Aβ 60 Wnt beta catenin 60 transcriptional coactivator 60 hormone aldosterone 60 mTOR mammalian target 60 MTHFR 60 Smurf1 60 serum lipid 60 enzyme COX 60 PKC beta 60 tumor suppressive 60 NOD2 60 serine threonine 60 apo AI 60 IL 1beta 60 SLC#A# [002] 60 p# mitogen activated 60 cell motility 60 signaling cascade 60 serum cholesterol 60 adenosine A2A receptor 60 CYP#C# [002] 60 nAChRs 60 metabolic abnormalities 60 small molecule agonists 60 prolyl 60 anti apoptotic 60 adenosine receptors 60 ERK2 60 receptor gene 60 NADPH oxidase 60 peripheral tissues 60 Akt activation 60 SGLT2 60 metabolic homeostasis 60 intercellular communication 60 Mcl 1 60 Adiponectin 60 metabolic alterations 60 physiologic functions 60 receptor PPAR 60 TSC1 60 MEF2D 60 Brain derived neurotrophic 60 myogenesis 60 miRNA expression 60 proteinases 60 cyclooxygenase COX 60 signal transduction pathways 60 NRF2 60 PHD2 60 neurotransmitter receptors 60 effector functions 60 microglial activation 60 dietary antioxidants 60 oxidative stress 60 Akt signaling 60 KLF# 60 Polyunsaturated fatty acids 60 serotonin transporter 60 myocyte 60 costimulation 60 PTEN protein 60 galectin 60 neurotransmitter receptor 60 CYP#E# 60 mitochondrial proteins 60 NF kB 60 genes encoding 60 PKC alpha 60 LRP1 60 antiapoptotic 60 prefrontal cortical 60 adrenergic receptors 60 HIF 1α 60 mevalonate 60 metabolic parameters 60 WNK1 60 phosphatases 60 natriuretic 60 GABAergic 60 E3 ubiquitin ligase 60 nAChR 60 cardiac hypertrophy 60 ion channels 60 motilin 60 apolipoprotein E 60 pigment epithelium derived 60 caveolae 60 vascular dysfunction 60 Runx2 60 mitochondrial oxidative phosphorylation 60 VLDL cholesterol 60 hydrolases 60 dopamine transporter 60 TRP channels 60 proNGF 60 c MET 59 HDAC2 59 metabolizing enzyme 59 NFkappaB 59 pathophysiological effects 59 SGK1 59 glycolytic 59 adaptive immunity 59 vascular inflammation 59 MAPK pathway 59 clusterin 59 ADAM# 59 molecular mechanisms 59 acyl CoA 59 nicotinic receptor 59 reductase 59 HIF1 alpha 59 lipid oxidation 59 kinase pathway 59 ERK1 59 secreted protein 59 5 hydroxytryptamine 59 STIM1 59 arginase 59 PGC1 59 NR#A# 59 neuromuscular junction 59 immunological mechanisms 59 oligomerization 59 insulin secreting cells 59 hormones ghrelin 59 beta amyloid peptide 59 Akt3 59 NFkB 59 VEGF expression 59 CPT1c 59 SIRT1 gene 59 mice lacking 59 transmembrane receptor 59 desmin 59 Rho GTPases 59 gamma aminobutyric acid GABA 59 vascular reactivity 59 pyrimidines 59 4E BP1 59 growth hormone secretion 59 autoantigens 59 IRF6 59 androgen receptor AR 59 phosphorylation 59 miR# 59 SIRT3 59 oxidative stress markers 59 IL #p# 59 beta arrestin 59 cholesterol absorption 59 NAD + 59 proximal tubule 59 glomerular 59 TGF beta 59 MEK1 59 acyltransferase 59 CCL5 59 β amyloid 59 proteoglycan 59 sphingolipid 59 NF kB pathway 59 hedgehog pathway 59 Ago2 59 HSP# 59 Smad4 59 mTOR pathway 59 glucocorticoid 59 RNA splicing 59 striatal dopamine 59 dopamine signaling 59 Jhdm2a 59 incretin hormones 59 Rap1 59 GATA4 59 59 steroidogenic 59 inflammatory markers 59 estrone 59 leukotriene pathway 59 Cyclin E 59 gene locus 59 chromosome condensation 59 pathogenic mechanisms 59 proteolytic 59 Cdk5 59 PINK1 59 LPA1 receptor 59 pro inflammatory cytokines 59 HDACs 59 glucose transporters 59 iNOS 59 synaptic vesicle 59 FGFR3 59 intestinal epithelial 59 receptor activation 59 hormone leptin 59 caveolin 1 59 actin dynamics 59 physico chemical properties 59 transcriptional repressor 59 proteins 59 adiponectin hormone 59 plasminogen 59 metabolic disorders 59 PPAR delta 59 lipid profiles 59 prostaglandin E 59 Six3 59 inflammasome 59 innate immune 59 calcium absorption 59 RANK Ligand 59 Oncogenic 59 CagA 59 Stat3 59 amyloid β 59 modifiable lifestyle 59 noncoding RNAs 59 circadian clock genes 59 circadian genes 59 STAT4 59 intracellular calcium 59 osteopontin 59 monocyte chemoattractant protein 59 perilipin 59 adiposity 59 metabolic dysfunction 59 cytoprotective 59 endothelial nitric oxide 59 #beta HSD1 59 exocrine 59 muscular dystrophies 59 APOE genotype 59 apoC III 59 hepatic stellate cells 59 NF κB 59 PTH secretion 59 bile acid 59 myopathies 59 cholecystokinin CCK 59 GATA3 59 neurotransmitters serotonin 59 E#F# 59 Thyroid hormones 59 Oxidative damage 59 arachidonic acid 59 prostaglandin E2 59 transcription factor 59 protein CETP 59 pancreatic alpha 59 secretion 59 PTP1B 59 protein 59 aldosterone hormone 59 spermatogenesis 59 glucocorticoid hormones 59 pRb 59 STAT3 signaling 59 Low density lipoprotein 59 FKBP# 59 PTP 1B 59 nitrotyrosine 59 Fas ligand 59 PTEN gene 59 neurohormones 59 lipopolysaccharide 59 coenzyme 59 acetylcholinesterase 59 CYP #A# 59 phosphatase 59 elastase 59 morphogenesis 59 GPx 59 dendritic spine 59 neurochemistry 59 adiponectin levels 59 protein tyrosine phosphatase 59 hypoxia inducible transcription 59 RAS RAF MEK 59 amino acid metabolism 59 H#K# [002] 59 leukocyte recruitment 59 uncoupling protein 59 osteoclast activity 59 myelination 59 Signal transduction 59 lipoic acid 59 beta adrenergic receptors 59 neuronal cells 59 endothelial 58 impaired glucose metabolism 58 beta catenin 58 amyloid formation 58 evolutionarily conserved 58 #ß 58 airway reactivity 58 morphogen 58 arachidonic acid AA 58 excitatory neurotransmitter 58 airway hyperresponsiveness 58 Wnt#b 58 Skeletal muscle 58 JAK2 enzyme 58 Hypothalamic 58 serotonin synthesis 58 GLUT4 58 PU.1 58 TSLP 58 cell adhesion molecules 58 tropomyosin 58 N myc 58 cathepsins 58 MAP kinase 58 humanin 58 hypoxia inducible 58 IKK beta 58 protein phosphatase 58 microcirculation 58 cysteine 58 SNCA 58 cyclooxygenase 58 receptor inhibitor 58 estrogen receptors 58 #ß HSD1 58 transcriptional regulators 58 galanin 58 heme oxygenase 58 NFκB 58 neuropsychiatric diseases 58 atherogenic 58 Gata4 58 MicroRNA 58 gene expression patterns 58 PIK3CA 58 dopamine receptor 58 abnormal angiogenesis 58 CYP#C# [001] 58 cyclin dependent kinase inhibitor 58 neurotrophic 58 allergic inflammation 58 somatostatin 58 FOXO1 58 Treg cell 58 dopamine D2 58 tryptase 58 focal adhesion kinase 58 mediated apoptosis 58 BDNF 58 Notch signaling pathway 58 coagulation cascade 58 HDAC9 58 molecular underpinnings 58 GTPase 58 abscisic acid 58 KIAA# 58 galectin 3 58 anti inflammatory cytokines 58 diabetic microvascular complications 58 lipoprotein 58 fat hormone leptin 58 CaM kinase 58 receptor tyrosine kinases RTKs 58 inflammatory mediators 58 baroreceptor reflex 58 GSK3B 58 Endothelial 58 Frizzled 58 fatty molecules 58 costimulatory 58 kinase domain 58 chromosomal regions 58 proinflammatory mediators 58 MMP# 58 cannabinoid receptor 58 breast cancer metastasis 58 homeostasis 58 catenin 58 epigenetic silencing 58 inverse agonist 58 vitamin D receptors 58 plasma lipoprotein 58 TORC1 58 GSK3 58 phosphate S1P 58 gamma aminobutyric acid 58 alternative splicing 58 intracellular pH 58 serum lipids 58 Incretin 58 PIP2 58 angiotensin 58 VKORC1 58 FGFR1 58 chondrocyte 58 enzyme AMPK 58 apolipoproteins 58 COMT 58 NF KB 58 IRS1 58 Bcl xL 58 dietary intakes 58 alpha7 NNR 58 cardiac fibrosis 58 GnT 4a 58 SREBP 1c 58 nitric oxide synthase NOS 58 polycystin 58 CDK5 58 cyclic AMP 58 isoenzyme 58 immunoregulatory 58 endocrine abnormalities 58 peripheral insulin sensitivity 58 monounsaturated fatty acid 58 dietary DHA 58 phosphoinositide 58 neuronal cell 58 c MYC 58 ß catenin 58 thromboxane A2 58 Genetic variation 58 AMPK 58 DNA methylation 58 Aß 58 metalloproteinases 58 lipid peroxides 58 CCR9 58 primary cilia 58 aberrant activation 58 vasodilatation 58 protein conformation 58 hydroxylase 58 dopamine D2 receptors 58 PI3K Akt 58 TNFR 58 protein kinase 58 glutamate receptor 58 phospholipase 58 protein SIRT1 58 potentially modifiable 58 glucosides 58 LDLR 58 TMPRSS6 58 GTPases 58 PPARs 58 epigenetic 58 ribosomal protein 58 murine model 58 fibrotic disease 58 angiotensin II receptor 58 proton pump 58 prostanoids 58 MMP7 58 Cdc7 58 neuronal synapses 58 H#K# [001] 58 biosynthetic pathways 58 V#F mutation 58 cardioprotective effects 58 neurohormone 58 serum triglycerides 58 cellular organelles 58 soluble fms 58 urocortin 58 triglyceride synthesis 58 STAT3 58 palmitoylation 58 exocytosis 58 neuroligins 58 serum leptin 58 KEAP1 58 HIF 1a 58 Prolactin 58 Prox1 58 metabolic acidosis 58 ischemia reperfusion injury 58 breast carcinogenesis 58 ovarian hormones 58 bone resorption 58 deacetylation 58 nephronophthisis 58 KCNE2 58 Androgen receptor 58 oligosaccharides 58 gene loci 58 neuroprotective effects 58 Elevated serum 58 glycogen synthesis 58 p#INK#a 58 NR2B subunit 58 S#K# 58 cytokine receptor 58 epithelial barrier 58 contractility 58 xanthine 58 RANKL 58 GSTT1 58 thyrotropin 58 microtubule dynamics 58 neuronal nitric oxide synthase 58 cyclic AMP cAMP 58 neurotransmitter glutamate 58 intracellular 58 tRNA synthetase