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(Click for frequent words.) 71 signaling pathways 70 molecular pathways 69 cellular pathways 69 metabolic enzymes 69 metabolic processes 68 signaling pathway 67 biological pathways 67 lipid metabolism 66 biochemical pathways 66 proteins 66 biochemical mechanisms 66 biosynthetic pathways 66 biochemical pathway 65 chromatin structure 65 biochemical processes 65 actin cytoskeleton 65 cellular signaling pathways 65 enzymes 65 histone modifications 64 metabolic pathway 64 adult neurogenesis 64 cell signaling pathways 64 genes 64 calpain 64 fatty acid metabolism 64 signaling cascades 63 enzymatic pathways 63 micro RNAs 63 secretory pathway 63 transcriptional regulation 63 epigenetic mechanisms 63 intracellular proteins 63 glutamate receptors 63 protein kinases 63 oxidative phosphorylation 63 MEF2D 63 gut microbiota 63 synaptogenesis 63 mitochondrial 63 proteolysis 62 Wnt pathway 62 molecular pathway 62 selenoproteins 62 transcriptional coactivator 62 metabolic 62 neural circuits 62 intracellular pathways 62 glucocorticoid receptor GR 62 eukaryotic cells 62 gut microbes 62 cell signaling pathway 62 drug metabolizing enzymes 62 polyamines 62 TRP channels 62 cellular metabolism 62 autophagy 62 gene expression 62 neurotransmission 62 estrogen metabolism 62 Wnt signaling 62 neurite outgrowth 62 Notch signaling 61 podocyte 61 cellular organelles 61 cholesterol metabolism 61 ion channels 61 endocannabinoid system 61 MAPK 61 metabolizing enzymes 61 circadian clock genes 61 noncoding RNAs 61 receptor gamma 61 tRNA synthetase 61 RNA splicing 61 Ago2 61 biosynthesis 61 ncRNAs 61 peroxisome proliferator activated 61 Wnt signaling pathway 61 metabolism 61 ligases 61 enzymatic reactions 61 intestinal microflora 61 PPARg 61 chromatin remodeling 61 intracellular signaling 61 isoprenoid 61 MMPs 61 proteases 61 neuronal signaling 61 gut microflora 61 genes encoding 61 HSF1 61 epigenetic alterations 61 mitochondrial function 61 protein synthesis 61 mammalian cells 61 lysosomal 61 FOXO 61 gluconeogenesis 61 mitochondrial proteins 60 FOXO3a 60 non coding RNA 60 molecular underpinnings 60 signaling molecules 60 glucocorticoid receptor 60 transcription factors 60 p# pathway 60 synaptic transmission 60 hedgehog pathway 60 isoforms 60 molecular mechanisms 60 biologic pathways 60 MEF2 60 lipid synthesis 60 DISC1 60 signal transduction pathways 60 druggable target 60 chromosomal regions 60 hydrolases 60 synapse formation 60 HDACs 60 epigenetic regulation 60 biosynthetic pathway 60 carbohydrate metabolism 60 glycolipids 60 miRNAs 60 underlying molecular mechanisms 60 protein 60 peroxisomal 60 JNK1 60 5 hydroxymethylcytosine 60 sirtuin 60 Skp2 60 chloroplast 60 signal transduction 60 potent inhibitors 60 SIRT3 60 mitochondria 60 sphingolipids 60 SIRT1 60 gut flora 60 telomere maintenance 60 proteolytic 60 neuronal plasticity 60 metabolites 60 BMP signaling 59 adenosine A2A receptor 59 molecular mechanism 59 adipokines 59 phenotypes 59 p# activation 59 transcriptional 59 RUNX3 59 dopamine receptor 59 SIRT1 gene 59 NADPH oxidase 59 neuronal differentiation 59 intracellular signal transduction 59 SH2 B 59 MAPK pathway 59 p#/CBP 59 neural cells 59 lipoxygenase 59 TGF b 59 microRNAs 59 CYP#E# 59 glycosylation 59 mitochondrial oxidative phosphorylation 59 protein biosynthesis 59 SCD1 59 FGFs 59 synaptic plasticity 59 JAK STAT 59 axon guidance 59 calcineurin 59 neuronal circuits 59 NFκB 59 receptor subtypes 59 STAT3 59 innate immunity 59 PKC isoforms 59 Hedgehog signaling 59 effector proteins 59 serine proteases 59 intracellular signaling pathways 59 acyl CoA 59 epigenome 59 microRNA molecules 59 sphingolipid 59 intracellular 59 podocytes 59 membrane fusion 59 oxidase 59 mitogen activated protein kinase 59 lincRNAs 59 lipids 59 virulence factors 59 peroxisome 59 membrane receptors 59 Notch pathway 59 UCP2 59 cofactors 59 cathepsins 59 cytoskeletal 59 normal prion proteins 59 steroid hormones 59 miR #a [002] 59 SGK1 59 biogenesis 59 melanocortin receptors 59 protein kinase C 59 PPARγ 59 lipid rafts 59 ubiquitylation 59 naturally occurring enzyme 59 H#K# methylation 59 nodulation 59 neurotransmitter receptor 59 arginase 59 neuromuscular junction 58 posttranslational modification 58 mutant huntingtin protein 58 morphogens 58 COX enzymes 58 Smad3 58 nAChRs 58 histone deacetylases 58 Klf4 58 proto oncogene 58 NMDA receptor 58 disulfide bond 58 FOXO1 58 tumor suppressor protein 58 XBP1 58 FoxO1 58 epigenetically 58 Hypoxia Inducible Factor 58 mRNA molecules 58 outer membrane proteins 58 Rho GTPases 58 yeast genome 58 fission yeast 58 4E BP1 58 heparan sulfate 58 Hox gene 58 enzyme 58 autophagic 58 ERK1 2 58 KIAA# 58 nicotinic receptors 58 cyclins 58 molecular mechanisms underlying 58 homologs 58 HIF 1α 58 histone modification 58 excitatory neurotransmitter 58 enzymatic pathway 58 tyrosine phosphorylation 58 cellulases 58 Sirt1 58 epigenetic 58 plasminogen 58 Dictyostelium 58 operon 58 ERK2 58 gene locus 58 Rab# 58 gene expression patterns 58 LKB1 58 methylation patterns 58 TORC2 58 neuropsychiatric diseases 58 EGFR signaling 58 PPAR alpha 58 intracellular protein 58 transcriptional repressor 58 carcinogenesis 58 posttranslational modifications 58 PI3K AKT 58 p# MAPK 58 virulence genes 58 Wnt proteins 58 ERK pathway 58 genetic determinants 58 phagocytosis 58 serine threonine 58 organelle 58 microRNAs miRNAs 58 cofactor 58 protein kinase 58 Wnts 58 mRNAs 58 cyclophilin D 58 mevalonate 58 messenger RNAs 58 miRNA 58 chloroplasts 58 spermidine 58 beta catenin 58 acetylcholine receptors 58 lipoprotein metabolism 58 substrate specificity 58 MAP kinases 58 tumorigenesis 58 mutant proteins 58 glycolytic 58 homodimers 58 neurotransmitter receptors 58 riboswitches 58 mutated protein 58 catabolism 58 RNA sequences 58 GSK3 58 Vps# 58 paxillin 58 Rap1 58 evolutionarily conserved 58 DLC1 58 serotonin receptor 58 acetylcholine receptor 58 signaling molecule 58 proline 58 oxidases 58 uPAR 58 miRNA expression 58 sRNA 58 fungal genomes 58 ubiquitination 58 epigenetic changes 58 metazoans 58 stem cell differentiation 58 oncogenesis 58 galectins 58 LRP1 58 neurobiological mechanisms 58 neurosteroids 58 ERK1 58 dopamine transporter 58 serine threonine kinase 58 neurosteroid 58 neurotransmitter serotonin 58 neurones 58 superfamily 58 ryanodine receptor 57 Rab5 57 PKC alpha 57 mTOR signaling 57 organelles 57 eicosanoid 57 NMDA receptors 57 causative genes 57 casein kinase 57 operons 57 protein misfolding 57 Hsp# [001] 57 tumor microenvironment 57 synaptic function 57 calcium homeostasis 57 synapse maturation 57 leptin signaling 57 TXNIP 57 FGFR1 57 fatty acid biosynthesis 57 intestinal microbiota 57 apoE 57 membrane proteins 57 PPAR gamma 57 gene 57 biochemically 57 PI3K signaling 57 bacterial toxins 57 auxin 57 physiological mechanisms 57 TNFa 57 bacterial enzyme 57 c Abl 57 intestinal epithelium 57 neuroligin 57 TRAF6 57 subcellular compartments 57 cell motility 57 lysosome 57 GABAergic 57 DARPP 57 cardiac fibroblasts 57 normal prion protein 57 protein conformation 57 MC4R 57 Photosystem II 57 protein tyrosine phosphatases 57 xenobiotic 57 MAP kinase 57 mechanistically 57 TGF β 57 NAD + 57 circadian genes 57 endogenous ligands 57 Hh pathway 57 chromosome condensation 57 Amyloid Precursor Protein 57 metalloprotease 57 cannabinoid receptors 57 NF KB 57 FGF signaling 57 oxidized LDL 57 transcription factor 57 eukaryotic 57 GluR1 57 trans splicing 57 PI3K Akt 57 mRNA translation 57 SH#B# 57 chitinase 57 proteostasis 57 ligands 57 myogenesis 57 eukaryotes 57 KLF4 57 mRNA expression 57 Pol IV 57 matrix metalloproteinases 57 neuronal synapses 57 histone code 57 microglial 57 amylin 57 ERK signaling 57 paralogs 57 PIP2 57 pathogenesis 57 regulates gene expression 57 alpha synuclein toxicity 57 intercellular communication 57 HCV replication 57 Kv#.# 57 neuronal dysfunction 57 PTEN gene 57 PI3K pathway 57 ribosomal RNA 57 PKM2 57 synaptic vesicle 57 stem cell pluripotency 57 apoptotic pathway 57 oncoprotein 57 serotonin transporter 57 enzymatic activity 57 LXRs 57 fatty acid synthesis 57 NF kappaB 57 oligomeric 57 dystroglycan 57 phosphorylates 57 HOTAIR 57 S#K# 57 RNA polymerases 57 HDAC2 57 cell adhesion molecules 57 kinase domain 57 peroxisomes 57 GABA receptors 57 DLX5 57 mitochondrial biogenesis 57 interconversion 57 membrane protein 57 histone acetylation 57 prostaglandin synthesis 57 tropomyosin 57 adipocyte 57 pathogenic mechanisms 57 acetyl CoA 57 DNA methylation patterns 57 acetylation 57 DNA demethylation 57 glycogen metabolism 57 insulin signaling pathway 57 Runx2 57 TIR1 57 dopamine receptors 57 γ secretase 57 phosphatases 57 sortilin 57 glucose homeostasis 57 Skeletal muscle 57 Rubisco 57 eicosanoids 57 dopamine signaling 57 molecular 57 isotypes 57 constitutively expressed 57 laforin 57 GABA receptor 57 E1A 57 Hfq 57 costimulatory 57 effector molecules 56 phytochrome 56 genetic underpinnings 56 tumor suppressor genes 56 Caspases 56 APOBEC3G 56 androgen receptor 56 proton pump 56 RNAi pathway 56 plastid 56 Rho proteins 56 enzyme inhibitors 56 neuronal function 56 Htt 56 NF kB pathway 56 insulin receptors 56 Genetic variations 56 oncogenes 56 lipases 56 transcriptional activation 56 subcellular localization 56 PTPN# 56 NF κB 56 molecular biomarkers 56 LIS1 56 GABAA receptors 56 eukaryotic cell 56 presenilin 56 protein secretion 56 inhibitory 56 alpha synuclein 56 superoxide dismutase 56 microbiota 56 dopaminergic 56 C. elegans 56 S nitrosylation 56 Dpp 56 neurotransmitters 56 SUMOylation 56 ubiquitin ligase 56 centrosome 56 activin 56 transcriptional regulators 56 molecules 56 CPT1c 56 neuronal circuitry 56 nematode Caenorhabditis elegans 56 p# mutations 56 TOR pathway 56 proteasomes 56 Cdc7 56 phospholipase 56 mitochondrion 56 Transcription factors 56 TMEM#B 56 gene polymorphisms 56 glycoproteins 56 AgRP neurons 56 protein alpha synuclein 56 copper zinc superoxide 56 PPAR delta 56 Shh signaling 56 CD1d 56 aberrantly activated 56 RNA binding 56 intracellular bacteria 56 genetic polymorphisms 56 cytoskeleton 56 intestinal epithelial 56 Akt3 56 adipogenesis 56 amino acids 56 MeCP2 56 alternative splicing 56 pre mRNA splicing 56 catenin 56 biosynthetic enzymes 56 apoE4 56 neural crest 56 BMAL1 56 interleukin 1beta 56 amino acid 56 Histone 56 muscular dystrophies 56 rRNA 56 retinoid X 56 binding proteins 56 biochemical 56 caveolin 56 eNOS 56 biochemical reactions 56 PON1 56 collagens 56 octopamine 56 IL 1β 56 cPLA2 56 GSK3B 56 pathogen interactions 56 mitochondrial metabolism 56 hematopoietic cells 56 E3 ligase 56 amyloid fibers 56 NFkappaB 56 thrombospondin 56 FGF2 56 progranulin 56 neurons 56 bacterium Escherichia coli 56 intracellularly 56 unicellular organism 56 hypocretin 56 SOD1 56 glycan 56 yeast Saccharomyces cerevisiae 56 hypoxia inducible factor 56 adaptive immunity 56 mammalian genomes 56 nAChR 56 prostanoids 56 neuronal pathways 56 regulate gene expression 56 protein complexes 56 primary cilia 56 neurofibromin 56 biological molecules 56 GAPDH 56 deacetylation 56 SREBP 56 tyrosine kinases 56 regulating gene expression 56 mitochondrial enzymes 56 quantitative trait loci 56 CB1 receptors 56 coding RNA 56 effector protein 56 netrin 1 56 centromeres 56 synaptic proteins 56 neuronal 56 histone methylation 56 endonucleases 56 subcellular 56 cortical circuits 56 PrPC 56 senescent cells 56 cypin 56 S1P 56 TGF beta pathway 56 beta adrenergic receptors 56 protease enzyme 56 CB2 receptor 56 β catenin 56 protease enzymes 56 Orexin 56 TGF ß 56 proinflammatory 56 NF kappaB pathway 56 habenula 56 Alu elements 56 innate immune responses 56 NR2B 56 eotaxin 56 telomeric 56 hematopoiesis 55 bacterial virulence 55 ADAM# 55 hyperactivation 55 pRb 55 WNK1 55 transcriptional machinery 55 bioactive compounds 55 JAK2 enzyme 55 dysregulated 55 protein tyrosine kinase 55 Pten 55 KLF# 55 missense mutations 55 bile acid 55 AMPA receptor 55 myo inositol 55 Fc receptor 55 HPA axis 55 abscisic acid 55 galactose 55 CHD7 55 AMPA receptors 55 disulfide bonds 55 endogenous cannabinoids 55 LDL receptor 55 homologous recombination 55 tumor metastasis 55 cysteine 55 angiotensinogen 55 interleukins 55 receptor subtype 55 mesenchymal cells 55 pathways 55 encodes protein 55 Vpr 55 insulin signaling pathways 55 NF kB 55 Cdc# 55 degrading enzymes 55 RNAs 55 VE cadherin 55 mGluRs 55 HIF1 alpha 55 IL 7R 55 LSD1 55 glutamate 55 pleiotropic effects 55 TLR4 55 inosine 55 genetic loci 55 metazoan 55 mitochondrial genes 55 PTP1B 55 Notch receptor 55 ENaC 55 proteomes 55 circadian clocks 55 biochemical signaling pathways 55 mTOR pathway 55 neural circuitry 55 NAADP 55 HMG CoA reductase 55 ribosomal proteins 55 anabolism 55 MEK1 55 S. cerevisiae 55 dietary restriction 55 bioactive molecules 55 chemical messengers 55 receptors 55 PTEN protein 55 Id1 55 adiponectin hormone 55 phenotype 55 adenosine receptors 55 coactivators 55 GABAB receptors 55 synthases 55 beta globin gene 55 lipopolysaccharide 55 cysteine residues 55 Hedgehog pathway 55 alpha synuclein gene 55 receptor proteins 55 beta1 integrin 55 p# tumor suppressor 55 NF kB signaling 55 pyrimidines 55 MAPKs 55 glycosaminoglycans 55 mitochondrial enzyme 55 molecule 55 BACE1 55 gene transcription 55 miR #a [001] 55 lung epithelium 55 mitochondrial gene 55 PGC1 55 Src 55 ncRNA 55 glucosides 55 immunomodulatory effects 55 Cyclin D1 55 synthetase 55 STAT1 55 effector functions 55 epigenetic silencing 55 Smoothened 55 antiapoptotic 55 transmembrane receptor 55 airway remodeling 55 cyclic AMP 55 CEACAM1 55 nucleases 55 colorectal carcinogenesis 55 PPAR γ 55 c Myb 55 dehydrogenases 55 DGAT1 55 DNMT1 55 hypocretin neurons 55 circadian rhythms 55 splice variants 55 signaling cascade 55 c MET 55 Dysregulation 55 matrix metalloproteinases MMPs 55 Nrf2 55 RhoA 55 galanin 55 cannabinoid receptor 55 plastids 55 cytochrome P# 55 glutamatergic 55 glucocorticoid receptors 55 cytochromes P# 55 mTOR 55 genes encode proteins 55 prodynorphin 55 metalloproteins 55 oligosaccharide 55 Nup# 55 S6K 55 lymphocyte activation 55 cortical neurons 55 opioid receptor 55 cholesterol efflux 55 astrocyte 55 neurogenesis 55 molecular interactions 55 LRRK2 55 muscle contractility 55 porphyrins 55 symbiotic bacteria 55 Akt1 55 isozymes 55 misfolded protein 55 neuroligins 55 protein folding 55 cyclin D1 55 tumor suppressor proteins 55 pharmacologically 55 epigenetic marks 55 transgene expression 55 biotransformation 55 membrane permeability 55 tRNA synthetases 55 selective inhibition 55 palmitate 55 mammary cells 55 secreted proteins 55 pathophysiological 55 chaperone proteins 55 insulin secreting cells 55 digesting enzymes 55 coding genes 55 exocytosis 55 receptor gene 55 BubR1 55 PAK1 55 SMN2 55 root nodules 55 prokaryotic 55 transcriptome 55 cyclin dependent kinases 55 enzyme COX 55 heterochromatin 55 demethylase 55 act synergistically 55 axon outgrowth 55 HSCs 55 RecA 55 ALDH2 55 symbiont 55 neurochemical 55 RNA molecules 55 protein glycosylation 55 metabolic homeostasis 55 ATPase 55 heterodimers 55 adhesion molecule 55 PIP3 55 enzymatic 55 macrophage activation 55 skeletal muscle 55 inhibit enzymes 55 hippocampal neurons 55 urocortin 55 neurocircuitry 55 chromosomal DNA 55 methyltransferases 55 species ROS 55 hypothalamic 55 budding yeast 55 orexin 55 HDAC6 55 protein phosphorylation 55 polysaccharides 55 MALAT1 55 uncoupling protein 55 binding affinities 55 lipid homeostasis 55 phosphatidylinositol 3 55 androgen receptor AR 55 hydrogenase 55 pharmacological inhibition 55 nitrogenase 55 TAp# 55 biochemical assays 55 hippocampal cells 55 neurite 55 neuropeptides 55 toxic beta amyloid 55 epithelial tissues 55 Siglec 8 55 ABCA1 55 intestinal epithelial cells 55 non coding RNAs 55 peptide hormone 55 serine protease 55 Sir2 55 metabolize cholesterol 55 tau protein 55 NKT cells 55 neuregulin 55 FGFR2 55 glutamine 55 fatty acid synthase 55 vitamin D receptors 55 oligomerization 55 TGF beta 55 FGFR3 55 immunological mechanisms 55 telomerase enzyme 55 IKK beta 55 isoenzymes 55 tRNAs 55 neural mechanisms 55 somatostatin 55 tyrosine 55 leptin receptor 55 Stat3 55 yeast cells 55 transmembrane proteins 54 extracellular signal 54 post transcriptional 54 multipotent stem cells 54 peroxynitrite 54 HipA 54 GnRH neurons 54 oxysterols 54 enzyme AMPK 54 serotonin signaling 54 vacuolar 54 prostaglandin E2 54 CPEB 54 Drosha 54 topoisomerases 54 FANCD2 54 neural pathways 54 vascular endothelial 54 micro RNA 54 cytokine 54 MDSCs 54 cdk5 54 biochemical cascade 54 Hox genes 54 Smurf1 54 cAMP signaling 54 gamma aminobutyric acid GABA 54 telomere DNA 54 IKKß 54 coexpression 54 glycolysis 54 kinase pathway 54 roundworm C. elegans 54 lectins 54 secreted protein 54 xanthine 54 antisense RNA 54 small RNAs 54 inositol 54 hypothalamic pituitary 54 Argonaute proteins 54 biosynthetic 54 P#s [002] 54 PKC enzyme 54 redox active 54 C. jejuni 54 molecular abnormalities 54 Rad# 54 physiologic mechanisms 54 hypothalamic pituitary adrenal axis 54 hormone secretion 54 coactivator 54 gamma secretase 54 pseudogenes 54 genetic polymorphism 54 genetic variants 54 transduce 54 reproductive hormones 54 malonyl CoA 54 prolyl 54 piRNAs 54 cellular senescence 54 microglial cells 54 thyroid hormones 54 inhibitory neurotransmitters 54 SIRT2 54 Phosphorylation 54 helicases 54 gene rearrangements 54 endonuclease 54 LRRK2 gene 54 opiate receptors 54 glyceraldehyde 3 54 E#F# 54 Amino acid 54 synthase 54 Cdk5 54 palmitoylation