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(Click for frequent words.) 77 rats 74 mutant mice 72 knockout mice 71 transgenic mice 71 deficient mice 70 mutant flies 69 Mice 67 genetically engineered mice 66 mice genetically engineered 66 genetically altered mice 65 mice lacking 64 rodents 63 rhesus monkeys 63 mutant worms 63 mouse embryos 63 diabetic mice 62 neurons 62 breast epithelial cells 62 fruit flies 62 dopamine neurons 62 leptin deficient 61 mice genetically altered 60 genetically modified mice 60 nematode worms 60 neurones 60 hippocampal neurons 60 cultured cells 60 leptin 60 splenocytes 60 PTP1B 59 cultured neurons 59 mammary cells 59 rhesus macaque monkeys 59 mammary tumor formation 59 myocytes 59 TRPA1 gene 59 mouse 59 mutant proteins 59 diabetic rats 59 D2 receptors 59 kisspeptin 58 leptin receptors 58 rat pups 58 neuroblastoma cells 58 CB1 receptors 58 yeast cells 58 monkeys 58 luteolin 58 astrocytes 58 zebrafish 58 fibroblast cells 58 stress hormone corticosterone 58 ES cells 58 Mice lacking 58 mutant mouse 58 neural cells 58 transgenic rats 58 BDNF 58 neuronal cells 58 MPTP 58 podocytes 58 IKK2 58 Sprague Dawley rats 57 C. elegans 57 experimentally induced 57 CD8 T cells 57 humanized mice 57 Wnt signaling 57 corticosterone 57 atypical neuroleptics 57 CD8 cells 57 uncoupling protein 57 Hsp# [001] 57 PrP 57 retinal cells 57 rhesus macaques 57 littermates 57 fruitflies 57 FGF# 57 C#BL 6 mice 57 mutant zebrafish 57 ovariectomized 57 BALB c 57 follistatin 57 stathmin 57 Mutant mice 57 Foxp3 56 hamsters 56 overexpressing 56 lung fibroblasts 56 bone marrow stromal cells 56 serotonin receptor 56 leptin deficient mice 56 telomerase gene 56 lab rats 56 ChR2 56 immunized mice 56 insulin receptors 56 IGF2 56 RGS2 56 mutant protein 56 glioblastoma cells 56 CatB 56 mammalian cells 56 skeletal muscle cells 56 murine 56 TrkB 56 PC# cells 56 nerve cells 56 Mice genetically engineered 56 S#K# 56 cyclophilin D 56 mammary gland tumors 56 endostatin 56 Arabidopsis plants 56 orexin receptors 56 ob ob mice 56 Stat1 56 TNFa 56 cardiac myocytes 56 Jhdm2a 55 Akt1 55 inbred strains 55 PPARγ 55 mutant strains 55 CCR7 55 normal littermates 55 C EBP alpha 55 neural stem cells 55 mutant alleles 55 hypothalamic neurons 55 Transgenic mice 55 fibrous tangles 55 Prox1 55 cardiomyocytes 55 roundworms 55 Neural stem cells 55 ob ob 55 transgenic mouse 55 chimeric mice 55 cells 55 neuroD2 55 granule cells 55 IGF1 55 nNOS 55 genetically altered mouse 55 meadow voles 55 immune cells 55 cyclopamine 55 Kv#.# channels 55 neurogenesis 55 hippocampal cells 55 solitary locusts 55 leptin receptor 55 transgenic mouse model 55 olfactory neurons 55 BDNF gene 55 CaMKII 55 SH2 B 55 calorically restricted 55 stathmin gene 55 Nrf2 55 glucocorticoid 55 chitinase 55 NPY AgRP neurons 55 microglial cells 55 tumor cells 55 NFkB 55 PGE2 55 SGS# 55 fibroblasts 55 induced apoptosis 55 XBP1 55 S#A# [002] 55 NKT cells 54 GRK2 54 ErbB4 54 Notch signaling 54 receptor 54 mutant mice lacking 54 Wistar rats 54 Klotho gene 54 GABAergic neurons 54 zebrafish embryos 54 neural crest cells 54 untreated mice 54 chick embryos 54 ovalbumin 54 neuropeptide Y 54 PKM2 54 BACE1 54 midgut 54 germ cells 54 PrP gene 54 klotho 54 TGF ß 54 cofilin 54 Sirt3 54 macrophages 54 glioma cells 54 experimental autoimmune encephalomyelitis 54 BALB c mice 54 transfected cells 54 Uch L1 54 worm C. elegans 54 goblet cells 54 receptors 54 fumagillin nanoparticles 54 TRAF6 54 enterocytes 54 GDNF 54 locomotor activity 54 NOD mice 54 prion proteins 54 siRNA knockdown 54 SIR2 gene 54 SIRT6 54 glutamate receptors 54 neural progenitor cells 54 ouabain 54 FGF2 54 p#Kip# 54 phenotype 54 somatostatin 54 transthyretin 54 beta spectrin 54 nonhuman primates 54 proteins 54 dopaminergic neurons 54 SIRT1 54 P. gingivalis 54 overexpress 54 OGG1 54 oncomodulin 54 Androgen receptor 54 HCV replication 54 GRFT 54 TAp# 54 CCR5 receptors 54 CEACAM1 54 POMC neurons 54 enzymatic activity 54 pancreatic cells 54 corticosterone levels 54 SOD1 protein 54 p# deficient 54 alveolar epithelial cells 54 melanoma tumors 54 neuronal stem cells 54 germline stem cells 54 mouse embryo 54 intestinal epithelial cells 54 microglia 54 enzyme 54 NK cells 54 cortical neurons 54 AdPLA 54 arrestin 54 furin 54 mammary cancers 54 eotaxin 53 serotonin transporter 53 Ronald DePinho MD 53 endothelial cells 53 BMP signaling 53 excitatory synapses 53 LDLR 53 p# [001] 53 nicotinamide 53 Wwox 53 MEFs 53 neutralizing antibody 53 granulosa 53 lipin 53 CXCL# 53 cisplatin resistant 53 Treg cells 53 spermatogonia 53 iNOS 53 retinal degeneration 53 hepatocytes 53 activin 53 FoxO3 53 estrogen receptor alpha 53 trophoblast cells 53 beta adrenergic receptors 53 LRAT 53 Rhes 53 ghrelin 53 myoblasts 53 UCP2 53 antigenic epitopes 53 phthalate syndrome 53 cannabinoid receptors 53 db db mice 53 DLC1 53 pyruvate kinase 53 ERK2 53 Fragile X gene 53 Hcrt 53 Caenorhabditis elegans 53 hematopoetic stem cells 53 fruitfly Drosophila 53 vascular endothelial cells 53 dendritic cells DCs 53 SRT# [002] 53 BDNF protein 53 oxyntomodulin 53 vivo 53 SIRT1 gene 53 ß amyloid 53 Anopheles gambiae mosquitoes 53 stellate cells 53 CpG ODN 53 AMPK 53 insulin secreting cells 53 genes encoding 53 sonic hedgehog 53 male Sprague Dawley 53 protein 53 IGFBP 3 53 6 OHDA 53 Wnt 53 Leydig cells 53 genetically engineered mouse 53 Notch1 53 Panksepp studies 53 KLF# 53 prostate epithelial cells 53 SIRT3 53 PGC1 53 IL 1beta 53 Klotho 53 null mice 53 Wnt1 53 zebrafish embryo 53 hairless mice 53 toxic beta amyloid 53 pancreatic islet 53 adenovirus 53 antisense inhibition 53 pDCs 53 receptor gene 53 inhibitory 53 DGAT1 53 MIF gene 53 overexpression 53 PPAR gamma 53 flavopiridol 53 phagocytes 53 GLUT4 53 nestin 53 dopamine receptor 53 xenograft tumors 53 gene 53 SOCS1 53 adult neurogenesis 53 Paneth cells 53 mutated protein 53 Wnts 52 STAT3 52 HSCs 52 cortical plasticity 52 dopamine receptors 52 ZFN modified cells 52 inhibitory neurons 52 tumor suppressor protein 52 Macaca mulatta 52 somatic stem cells 52 glucocorticoid receptors 52 lymphoid cells 52 hormone adiponectin 52 neurotrophic factor 52 macrophage 52 rat neurons 52 bone marrow stem cells 52 elastase 52 PIP3 52 motoneurons 52 receptor inhibitor 52 MeCP2 52 heterozygotes 52 rapamycin 52 IFN gamma 52 soluble receptor 52 CLL cells 52 mammary tumors 52 hair follicle stem cells 52 bacterium Escherichia coli 52 endocannabinoids 52 mouse embryonic fibroblasts 52 mutant SOD1 52 genetic alteration 52 protein fragment 52 glucocorticoids 52 Genetically engineered mice 52 Math1 52 pDC 52 recessive mutation 52 lipid accumulation 52 alpha4 52 mitogen 52 hedgehog pathway 52 CIB1 52 forskolin 52 fumagillin 52 receptor protein 52 neuron degeneration 52 NMDA receptors 52 dopamine signaling 52 Neu5Gc 52 wildtype 52 NFATc1 52 M. vaccae 52 atherosclerotic lesions 52 mitochondrial proteins 52 Akt phosphorylation 52 immunodeficient mice 52 PBMCs 52 androgen receptors 52 TRIM5 52 syngeneic 52 CRF1 receptor 52 preadipocytes 52 mole rats 52 mouse testes 52 STAT4 52 monocytes 52 sortilin 52 neuroprotective effects 52 Rhesus monkeys 52 transgene expression 52 colorectal tumor 52 c Myc 52 PKC beta 52 proinsulin 52 neurotrophin 52 MC4R gene 52 TNFalpha 52 brain lesions 52 methylation patterns 52 NPY expression 52 osteocalcin 52 thymosin 52 Fibroblasts 52 PPAR delta 52 longdaysin 52 C#BL 6 52 kalirin 52 GFP gene 52 keratins 52 Dicer enzyme 52 PYY3 52 reprogrammed cells 52 mRNA transcripts 52 BMP4 52 HepG2 cells 52 Mus musculus 52 rodent 52 LXRs 52 mutant huntingtin 52 p# alpha [001] 52 irradiated mice 52 oxidized lipids 52 bioengineered mice 52 phagocyte 52 Sonic Hedgehog 52 cells overexpressing 52 TGF beta pathway 52 planarian 52 prion protein gene 52 vasopressin 52 CD4 + cells 52 transgene 52 rhodopsin 52 SIRT1 protein 52 Hoxb8 52 netrin 1 52 calcineurin 52 Hh 52 acinar cells 52 Treated mice 52 autophagic 52 E cadherin 51 neuroligin 51 Drosophila 51 HSP# 51 Sonic hedgehog 51 TGFb 51 mdx 51 cyclin E 51 streptozotocin 51 miR #a [002] 51 SOCS3 51 BH4 51 immunoreactivity 51 GPR# [002] 51 metabolizing enzyme 51 ovarian follicles 51 SIV infected 51 vomeronasal organ 51 myo inositol 51 gene encoding 51 CD#c 51 gene p# 51 neuronal 51 myostatin gene 51 homozygotes 51 downregulated 51 opsin 51 defensins 51 intracellular 51 glutamate 51 adenosine receptor 51 herpes viruses 51 primary cilia 51 hormone leptin 51 Ets2 51 planarians 51 retinoic acid 51 alpha synuclein 51 progenitor cells 51 microRNA molecules 51 JAK2 enzyme 51 transfected 51 ATPase activity 51 FOXO1 51 PIP2 51 oligodendrocytes 51 CRTC3 51 GBM tumors 51 signaling molecule 51 lysophosphatidic acid 51 PrPSc 51 HU# [002] 51 Untreated mice 51 Mice deficient 51 dendritic cells 51 adipose cells 51 p# gene 51 EZH2 51 Marfan mice 51 xenografts 51 mesenchymal cells 51 malonyl CoA 51 C#Y 51 neurite outgrowth 51 dentate gyrus 51 adrenal cortex 51 transgenic mosquitoes 51 apoE 51 p# protein 51 phosphorylated 51 MSNs 51 rod photoreceptors 51 CRTC3 gene 51 morphogen 51 beta1 integrin 51 primordial germ cells 51 costimulatory 51 transgenic mouse models 51 mdx mice 51 skin fibroblasts 51 genetically reprogrammed 51 vasopressin receptor 51 connexin 51 macaques 51 Smad3 51 TGF beta 51 ERK1 2 51 Htt 51 Pten gene 51 C1q 51 islet cells 51 overexpressing cells 51 NKCC1 51 acetylcholinesterase 51 RYGB surgery 51 PGCs 51 TGF beta1 51 gamma secretase inhibitor 51 osteoblast 51 lentiviruses 51 Akt 51 hMSCs 51 biochemically 51 TLR2 51 ALDH2 51 UCP1 51 Pin1 51 gibbon ape 51 CB2 receptor 51 MDSCs 51 kappa opioid receptor 51 palladin 51 neprilysin 51 cortisol hormone produced 51 urocortin 51 receptor blocker 51 FUS1 51 metreleptin 51 piRNAs 51 HUCB cells 51 antibodies 51 experimentally infected 51 aP2 51 astressin B 51 Vpu 51 cholecystokinin CCK 51 worm Caenorhabditis elegans 51 myeloma cells 51 cyclic AMP 51 MnSOD 51 TET2 51 epithelial stem cells 51 calpain 51 ceramide 51 diphtheria toxin 51 FMR1 gene 51 upregulated 51 chimerism 51 granulocytes 51 TOR pathway 51 spermidine 51 TEL AML1 51 hunger hormone ghrelin 51 Myostatin 51 RKIP 51 ERa 51 cytokine interleukin 51 NRG1 51 MDM2 51 anti Neu5Gc antibodies 51 miR #b [001] 51 whipworm 51 Hh pathway 51 exocytosis 51 BRAF mutation 51 melanocyte stem cells 51 defensin 51 Tg# [002] 51 KLF4 51 ALDH 51 retinal neurons 51 basophils 51 HDAC2 51 mammary tumor 51 amygdalas 51 NMDA receptor 51 alpha synuclein toxicity 51 kainate 51 interferon gamma 51 dystroglycan 51 GPR# [001] 51 lethally irradiated 51 exendin 4 51 leptin signaling 51 FKBP# 51 CDK4 51 orexin 51 PINK1 51 lymphocytes 51 MAPK 51 cardiac fibroblasts 51 Pten 51 NADPH oxidase 51 retinoblastoma protein 51 suppressor gene 51 myostatin 51 Rb protein 51 IGFBP2 51 KCNH2 51 cAMP 51 senescent cells 51 β catenin 51 hyperactivation 51 CD# protein 51 TGF β 51 Caveolin 1 51 estradiol 51 nematode worm 51 N. benthamiana 51 fatty acid synthase 51 mutant p# 51 poxvirus 50 induced colitis 50 oxysterols 50 NAD + 50 paxillin 50 H#N# mAbs 50 mutant 50 granulosa cells 50 fru 50 SOD1 50 amylin 50 transgenic mice expressing 50 tetherin 50 gerbils 50 Helicobacter 50 p#NTR 50 mTORC1 50 superoxide dismutase 50 Purkinje cells 50 peptides 50 sialic acids 50 Cdx2 50 iPSCs 50 SCID mice 50 tadpoles 50 TGF ß1 50 adiponectin 50 valproic acid 50 PTHrP 50 pRb 50 tumor suppressor gene 50 lentivirus 50 striatal 50 glutamate transporters 50 Hh signaling 50 CRF receptors 50 PrPC 50 arcuate nucleus 50 cdk5 50 cells hESCs 50 GAPDH 50 obestatin 50 Wnt signaling pathway 50 Rad# 50 CCL# 50 LKB1 50 synapse formation 50 salivary protein 50 excitatory 50 photoreceptor 50 coreceptor 50 HBx 50 nAChR 50 receptor subunit 50 mitochondrial mutations 50 hamsters rats 50 hippocampal synapses 50 naturally occurring enzyme 50 WWP2 50 Immunohistochemical analysis 50 CXCR2 50 E. faecalis 50 PTEN gene 50 exocrine cells 50 signaling pathway 50 Sir2 50 IFNg 50 suppressor cells 50 TRPV4 50 Rapamycin 50 inhibitory effect 50 interferon pathway 50 cordless laser 50 TLR3 50 habenula 50 luciferase 50 PTPN# 50 Nrf2 pathway 50 T lymphocytes 50 GSTT1 50 constitutively expressed 50 glucocorticoid receptor 50 olfactory receptor neurons 50 postnatally 50 testes 50 cyclin D1 50 Bcl xL 50 IGFBP7 50 telomerase enzyme 50 platelet aggregation 50 prion gene 50 demethylase 50 transduced 50 nematode Caenorhabditis elegans 50 microglial 50 Prolla 50 vasopressin receptors 50 catenin 50 TRIM5a 50 ependymal cells 50 SATB1 50 mammary stem cells 50 PcG proteins 50 MEF2D 50 vitro experiments 50 leptin resistance 50 Cyclin D1 50 leucocytes 50 tyrosine hydroxylase 50 tumor xenografts 50 p# activation 50 AMPA receptors 50 BCL#A 50 IL 1β 50 mRNA expression 50 MMP2 gene 50 caspase 50 mammalian 50 pea aphid 50 NEIL1 50 Nf1 50 caloric restriction 50 peptide YY 50 Sox9 50 Prairie voles 50 TRPV3 50 motor neurons 50 MMP2 50 Siglec 8 50 dauer 50 caveolin 50 AMPA receptor 50 sporozoites 50 Notch receptor 50 GSTM1 50 c Abl 50 utrophin 50 estrogen receptors 50 TORC1 50 D2 receptor 50 vivo experiments 50 virulence genes 50 miR 50 electrically stimulated 50 cholinergic receptors 50 cannabinoid receptor 50 Irs2 50 melanopsin 50 hematopoietic cells 50 neutrophil 50 PGC 1alpha 50 diapause 50 Schwann cells 50 immunocompromised mice 50 PAK1 50 leukemic cells 50 PTEN protein 50 LDL receptor 50 glycosylation 50 aneuploid cells 50 SCN neurons 50 Or#b 50 hind paw 50 lymphocytic choriomeningitis 50 genes 50 isoforms 50 metyrapone 50 leptin hormone 50 leukemic stem cells 50 RUNX3 50 protein SIRT1 50 sirtuin 50 ciliates 50 engrafted cells 50 circulating lymphocytes 50 PKD1 50 arginase 50 maternal antibodies 50 Alu elements 50 myeloid cells 50 Nkx#.# 50 Fruit flies 50 demyelinated 50 Drosophila melanogaster 50 induced pluripotent cells 50 acetylcholine 50 epigenetically 50 melanocyte stimulating hormone 50 cystic fibrosis transmembrane conductance 50 Shp2 50 odorant receptor 50 IgG1 50 Th2 cytokines 50 DISC1 50 planaria 50 iPS cells 50 receptor molecule 50 SHANK3 50 NR2B subunit 50 trypanosome 50 mouse oocytes 50 interferon IFN 50 cat allergen 50 airway epithelial cells 50 glia 50 progerin 50 embryoid bodies 50 cysteine 50 intraperitoneal injection 50 RANKL 50 TRP channels 50 PPAR alpha 50 DNMT1 50 HSF1 50 constitutively 50 outer membrane proteins 50 immune responses 50 fatty acid metabolism 50 mutations 50 Stat3 50 epigenetic silencing 50 trypsin 50 cynomolgus monkeys 50 Wnt protein 50 MAPCs 50 genetic manipulations 50 epiblast stem cells 50 imprinted genes 50 RGS# 50 proteasomes 50 lymphocytic choriomeningitis virus 50 STAT1 50 osteoblasts 50 XPB 50 Wnt#b 50 N Myc 50 synaptic vesicles 50 OCT4 50 measles virus 50 allele 50 Siberian hamsters 50 brainstems 50 cysteines 50 mutant allele 50 MAP kinase 50 Th1 cells 49 peptoids 49 mutated gene 49 fetal hemoglobin 49 hormone angiotensin II 49 gastrointestinal tracts 49 glutamate receptor 49 PEPCK 49 heterozygous 49 spermatogonial stem cells 49 dystrophin 49 pigtail macaques 49 mesenchymal stem cells 49 larvae 49 glutamate signaling 49 mutants 49 proteases 49 brain derived neurotrophic 49 primordia 49 5 HT1A 49 neural progenitor 49 BMAL1 49 hypoxia induced 49 inhibited tumor 49 aromatase 49 MAPK pathway 49 amyloid deposits 49 PD# [005] 49 MEF2 49 colorectal tumors 49 stromal cells 49 ACAT2 49 CD#L 49 synaptic proteins 49 PDGFR 49 microfilariae 49 PP2A 49 E1A 49 WT1 49 neuropilin 49 putrescine 49 MCF7 cells 49 DUX4 49 glucose tolerance 49 beta1 49 TG2 49 metalloproteinases 49 C. pneumoniae 49 pituitary hormone 49 GH secretion 49 amyloid deposition 49 inosine 49 GHRH 49 airway hyper responsiveness 49 Tregs 49 PGC 1α 49 GLUT1 49 ENaC 49 clioquinol 49 glycoproteins 49 hypocretin 49 dopamine synthesis 49 Kv#.# 49 caveolin 1 49 odorant receptors 49 lipopolysaccharide 49 protein synthesis 49 potentiation 49 antibody IgE 49 inhibition