Related by context. All words. (Click for frequent words.) 69 cognitively normal 68 cognitive impairment 68 cognitive decline 65 mild cognitive 65 amnestic MCI 65 cognitive function 65 dementia 65 amnestic mild cognitive impairment 65 microalbuminuria 64 brain shrinkage 64 impaired glucose tolerance 63 metabolic syndrome 63 Alzheimer disease 63 impaired fasting glucose 62 prehypertension 61 Mild Cognitive Impairment 61 glucose intolerance 60 Mild cognitive impairment 60 MMSE scores 60 Alzheimer dementia 60 prediabetes 60 NAFLD 59 vascular dementia 59 subclinical hyperthyroidism 59 brain atrophy 59 MetS 58 Alzheimer disease AD 58 diabetes mellitus DM 58 subclinical hypothyroidism 57 cognitive functioning 57 cognitive 57 white matter hyperintensities 57 donepezil 57 kidney function 57 bulimia nervosa 56 ApoE4 56 Parkinson disease PD 56 hippocampal volume 56 APOE e4 gene 55 proliferative retinopathy 55 prehypertensive 55 insulin resistance 55 T1DM 55 cognitive deficits 55 APOE e4 55 relapsing remitting 55 FTLD 55 proliferative diabetic retinopathy 55 depressive symptoms 55 diabetic retinopathy 55 cognitive dysfunction 55 mild cognitive impairments 55 T2DM 55 impaired cognition 55 extrapyramidal symptoms 55 urate levels 55 HbA1c levels 55 cardiorespiratory fitness 55 osteopenia 54 relapsing remitting MS 54 cognition 54 elevated triglyceride levels 54 schizophrenia 54 aMCI 54 VaD 54 cognitive impairments 54 dementias 54 androgen deficiency 54 glucose metabolism 54 Alzheimer pathology 54 arterial thickening 54 perimenopausal women 54 narcolepsy cataplexy 54 OSAHS 54 subclinical atherosclerosis 54 metabolic syndrome MetS 54 subclinical 54 ApoE4 gene 54 cognitively intact 54 retinopathy 54 APOE4 54 amyloid plaque 54 LQTS 54 Alzheimer disease vascular dementia 53 advanced adenoma 53 nondepressed 53 transaminase levels 53 frontotemporal dementia 53 fasting glucose 53 fasting blood glucose 53 fasting glucose levels 53 colorectal adenomas 53 thyrotropin levels 53 Barrett esophagus 53 perimenopause 53 neurocognitive function 53 disease NAFLD 53 drusen 53 overt nephropathy 53 APOE ε4 53 psychosocial functioning 53 psychotic disorders 53 T2D 53 APOE gene 53 macroalbuminuria 53 atherosclerosis 53 cerebral infarction 53 euthymic patients 53 knee OA 53 nondemented 53 acute myelogenous leukemia AML 53 cognitive functions 53 familial hypercholesterolemia 52 Alzheimer 52 sporadic ALS 52 plasma homocysteine 52 psychotic symptoms 52 elevated depressive symptoms 52 hippocampal atrophy 52 subsyndromal 52 proteinuria 52 disease progression 52 diabetes mellitus 52 familial ALS 52 fasting insulin 52 Alzheimer Disease AD 52 adenoma 52 neuropathological 52 prediabetic 52 untreated sleep apnea 52 normotensive 52 gallstone disease 52 hyperuricemia 52 neovascular AMD 52 nondiabetic 52 polycystic ovary syndrome PCOS 52 neurofibrillary tangles 52 microbleeds 52 neuropsychiatric symptoms 52 coronary calcification 52 knee osteoarthritis 52 lung function 52 apnea hypopnea index 52 affective psychosis 52 APOE 52 basal cell nevus syndrome 52 homocysteine levels 52 benign breast 52 antihypertensive therapy 52 nonalcoholic steatohepatitis NASH 52 low ptau levels 52 Prehypertension 52 amyloid deposition 52 postmenopause 52 Haptoglobin 52 major depressive disorder 52 affective disorders 52 vascular cognitive impairment 51 albuminuria 51 uric acid levels 51 coronary artery calcium 51 endothelial dysfunction 51 Lewy bodies 51 autonomic dysfunction 51 affective psychoses 51 moderate renal impairment 51 vitamin B# deficiency 51 glucose tolerance 51 antidiabetic medication 51 nonalcoholic fatty liver 51 diastolic heart 51 carotid atherosclerosis 51 adenomas 51 onset Alzheimer disease 51 cardiovascular mortality 51 prodromal symptoms 51 HNPCC 51 intermittent claudication 51 Osteopenia 51 nonalcoholic steatohepatitis 51 advanced adenomas 51 MMSE 51 carotid IMT 51 Wernicke Korsakoff syndrome 51 neurocognitive deficits 51 non affective psychosis 51 olfactory dysfunction 51 poor metabolizers 51 neuropsychological 51 HNSCC 51 Major Depressive Disorder 51 psychotic illnesses 51 dopaminergic therapy 51 elevated CRP 51 Alzheimers Disease 51 kidney dysfunction 51 albumin excretion 51 urinary symptoms 51 fetuin 51 diagnose Alzheimer disease 51 generalized anxiety disorder 51 psychotic illness 51 diagnosing Alzheimer disease 51 progressive neurodegenerative disorder 51 coronary artery calcification 51 macular degeneration 51 atherogenic dyslipidemia 51 brain lesions 51 dietary glycemic index 51 impaired renal 51 multi infarct dementia 51 SORL1 51 cardiovascular disease 51 Cognitive impairment 50 neuropsychological tests 50 parkinsonism 50 NP CRNs 50 hematopoietic cancers 50 PCa 50 hydroxyvitamin D levels 50 amyloid pathology 50 neovascular 50 hippocampal function 50 silent myocardial ischemia 50 mood disorders 50 premenopausal 50 elevated triglycerides 50 onset Alzheimer 50 clinically insignificant 50 ADPKD 50 systolic hypertension 50 adjunctive ABILIFY 50 insulin resistance syndrome 50 reflux symptoms 50 ADAS Cog 50 premenopause 50 functional dyspepsia 50 thyroid dysfunction 50 calcium metabolism 50 coronary disease 50 onset diabetes 50 schizophrenia CIAS 50 colorectal polyps 50 irritable bowel syndrome IBS 50 verbal fluency 50 hepatic steatosis 50 metabolic abnormalities 50 left ventricular systolic 50 HbA 1c 50 hippocampal volumes 50 homozygous familial hypercholesterolemia 50 Framingham Offspring 50 cystatin C 50 Excessive daytime sleepiness 50 postmenopausal women 50 renal function 50 coronary artery disease 50 sarcopenia 50 serum folate 50 premorbid 50 dysthymia 50 atypical neuroleptics 50 MGUS 50 attention-deficit/hyperactivity disorder ADHD 50 CSF biomarkers 50 asymptomatic 50 LUTS 50 MMSE score 50 aMCI precursor 50 psychiatric disorders 50 nerve degeneration 50 neurocognitive functioning 50 levodopa therapy 50 colorectal adenoma 50 prostate cancer CaP 50 nonobese 50 cortical thinning 50 urate 50 elevated homocysteine 50 Alzheimers disease 50 State Examination MMSE 50 generalized epilepsy 50 neurocognitive 50 depressive symptomatology 50 hypothyroidism 50 choroidal neovascularization 50 1 diabetes T1D 50 beta amyloid plaque 50 hypochondriasis 50 fatty liver disease 50 eosinophilic asthma 50 glycemic diet 50 amyloid deposits 50 abdominal obesity 50 triglyceride levels 50 late onset hypogonadism 50 alcoholic fatty liver 50 lowest tertile 50 shorter telomere length 50 triglycerides 50 asymptomatic PAD 50 IBS C 50 GBA mutations 50 creatinine levels 50 hemoglobin A1c levels 50 neurodevelopmental outcome 50 sleep disordered breathing 50 cholinesterase inhibitor 50 GH deficiency 49 beta amyloid 49 nondiabetics 49 colorectal neoplasia 49 KIBRA 49 fasting plasma glucose 49 glycated hemoglobin levels 49 amyloid plaques 49 eGFR 49 poststroke 49 hyperactivity impulsivity 49 progranulin mutations 49 serum PSA 49 myelin breakdown 49 hepatic encephalopathy 49 cognitively impaired 49 homocysteine 49 PSADT 49 Insulin resistance 49 hereditary predisposition 49 metabolic acidosis 49 elevated blood glucose 49 metabolically healthy 49 asymptomatic carotid stenosis 49 retinitis pigmentosa 49 ADHD 49 atrial fibrillation 49 variable ptau levels 49 claudication 49 chromium picolinate supplementation 49 nondrinkers 49 Alzheimer Disease 49 NF1 49 C reactive protein 49 preeclampsia 49 pre menopausal 49 mL/min/#.# m 2 49 recurrent VTE 49 non aspirin NSAIDs 49 coronary heart 49 CrCl 49 levodopa 49 left ventricular diastolic 49 renal dysfunction 49 carotid stenosis 49 systemic lupus erythematosus SLE 49 serum folate concentrations 49 NAION 49 TEAEs 49 Chronic insomnia 49 untreated celiac disease 49 hypomania 49 Framingham Offspring Study 49 serum vitamin D 49 ischemic strokes 49 obstructive sleep apnea 49 baseline HbA1c 49 serum creatinine levels 49 valvular disease 49 CC genotype 49 alexithymia 49 idiopathic Parkinson disease 49 diabetes mellitus T2DM 49 APOC3 49 HDL2 49 hyposmia 49 confidence interval #.#-#.# 49 dysglycemia 49 reflux disease 49 adrenal function 49 neurodegenerative disease 49 CLA supplementation 49 CYP#D# 49 episodic migraine 49 gene variant 49 hypogonadal men 49 ischemic stroke 49 left ventricular hypertrophy 49 familial adenomatous polyposis 49 synaptic function 49 osteoporotic fracture 49 bipolar illness 49 nonadherence 49 undergoing radical prostatectomy 49 shorter telomeres 49 AREDS 49 postmenopausal breast cancer 49 prodromal 49 retinitis pigmentosa RP 49 Depressive symptoms 49 MS relapses 49 primary ovarian insufficiency 49 abstainers 49 hemoglobin A1c HbA1c 49 POAG 49 hsCRP levels 49 Anxiety disorders 49 COPD 49 telomere length 49 inflammatory polyarthritis 49 lipid lowering medications 49 tau tangles 49 APOE allele 49 fructose intake 49 VADT 49 depressive disorders 49 diastolic dysfunction 49 thyroid function 49 Sarcopenia 49 hepatic fibrosis 49 frontotemporal dementia FTD 49 comorbid anxiety 49 Obstructive sleep apnea 49 folate deficiency 49 related macular degeneration 49 comorbid depression 49 β amyloid 49 primary generalized tonic 49 alanine aminotransferase ALT 49 infarcts 49 primary biliary cirrhosis 49 steatosis 49 hypertension 49 Alzheimer disease pathology 49 AGHD 49 polyp recurrence 49 SORL1 gene 49 chronic insomnia 49 obsessive compulsive disorder OCD 49 symptom severity 49 sleep disturbances 49 coronary calcium 49 hyperglycaemia 48 isolated systolic hypertension 48 spinocerebellar ataxia 48 neuropsychological deficits 48 nonmelanoma skin cancer 48 recurrent wheezing 48 PsA 48 apolipoprotein E4 48 lipid abnormalities 48 testosterone supplementation 48 nephropathy 48 hypercholesterolemic patients 48 dysthymic disorder 48 highest tertile 48 daytime alertness 48 SHPT 48 postmenopausal 48 neuropathologic 48 ARMD 48 serum cholesterol 48 creatinine clearance 48 venlafaxine XR 48 fructose intolerant 48 NIHSS score 48 migraineurs 48 penetrance 48 psoriatic arthritis PsA 48 neurodegenerative disorder 48 Binge eating 48 cardioembolic stroke 48 optic neuritis 48 recurrent atrial fibrillation 48 glycosylated hemoglobin 48 amino acid homocysteine 48 cholinesterase inhibitors 48 cataract formation 48 SRBD 48 telomere lengths 48 adenoma recurrence 48 steatohepatitis 48 VMAT2 48 Mini Mental 48 REM sleep behavior 48 beta blocker therapy 48 HDL cholesterol 48 inflammatory markers 48 FXTAS 48 bone density 48 endometrial hyperplasia 48 TOMM# 48 plasma folate 48 juvenile idiopathic arthritis 48 fragility fractures 48 seizure disorders 48 Hb A1C 48 neurodegeneration 48 hypertensives 48 daytime drowsiness 48 microscopic hematuria 48 MADRS score 48 motor neuron degeneration 48 prodromal phase 48 binge eating disorders 48 anxiety disorders 48 Neovascular AMD 48 systolic dysfunction 48 serum calcium 48 neurologic symptoms 48 unmeasured factors 48 Diabetes Mellitus 48 precursor mild cognitive 48 QTc 48 macular edema 48 GERD 48 angiotensin receptor blockers ARBs 48 open angle glaucoma 48 colon polyps 48 Hashimoto thyroiditis 48 adenomatous polyps 48 disorder PTSD 48 insulin sensitivity 48 non alcoholic steatohepatitis 48 lactose malabsorption 48 familial pancreatic cancer 48 hypersomnia 48 tarenflurbil 48 Alzheimer's 48 severe renal impairment 48 lipid lowering therapy 48 Impaired glucose tolerance 48 serum testosterone 48 recurrent acute pancreatitis 48 benign proliferative breast 48 EDSS score 48 pramlintide 48 airflow obstruction 48 borderline personality disorder 48 diastolic function 48 nonfasting triglycerides 48 elevated LDL cholesterol 48 hyponatremia 48 nonfasting triglyceride levels 48 HCV infected 48 uric acid 48 renal impairment 48 #q# deletion syndrome 48 rs# [002] 48 INVEGA ® 48 geographic atrophy 48 diabetes 48 severe hypoglycemia 48 tardive dyskinesia 48 amyloid 48 vestibular dysfunction 48 RLS symptoms 48 lipid levels 48 APOE genotype 48 retinal degeneration 48 maintaining cardiorespiratory fitness 48 comorbid disorders 48 gene APOE 48 metabolic disturbances 48 serum phosphate 48 glomerular filtration rate 48 AVODART 48 valproate 48 medial temporal 48 creatinine 48 medically unexplained 48 Parkinson Disease PD 48 heterozygous FH 48 postoperative pulmonary 48 cognitive abilities 48 fatty liver 48 atypical hyperplasia 48 CETP gene 48 sCJD 48 neuroimaging studies 48 Mood disorders 48 primary aldosteronism 48 sudden cardiac death 48 IgA deficiency 48 troponin T 48 abnormal lipid 48 paroxysmal AF 48 bipolar disorder 48 insulin resistant 48 Relapsing remitting MS 48 generalized anxiety disorder GAD 48 orthostatic hypotension 48 apolipoprotein E APOE 48 neoplasia 48 Sleep disordered breathing 48 estimated GFR 48 habitual snoring 47 Alzheimer's related 47 mIU L 47 severely cognitively impaired 47 cardiac dysfunction 47 LDL cholesterol levels 47 esophageal adenocarcinoma 47 abstinent alcoholics 47 slow metabolizers 47 clomipramine 47 autoimmune thyroiditis 47 beta amyloid plaques 47 affective disorder 47 serum urate levels 47 elevated serum creatinine 47 tHcy 47 alcoholic cirrhosis 47 macrovascular disease 47 neurocognitive impairment 47 citalopram 47 B# deficiency 47 fingolimod 47 unmeasured confounders 47 chronic pancreatitis 47 urinary albumin 47 myelodysplastic syndrome MDS 47 prefrontal regions 47 Rheumatoid Arthritis RA 47 Schizophrenia 47 gait disturbances 47 latent TB infection 47 rs# [003] 47 hypoglycemic episodes 47 Diabetic retinopathy 47 serum uric acid 47 liver fibrosis 47 relapsing remitting multiple sclerosis 47 elevated LDL 47 colorectal cancer 47 subcortical 47 Metabolic syndrome 47 mitochondrial function 47 clinically meaningful improvements 47 ApoE gene 47 serum creatinine 47 dietary calcium intake 47 overt hypothyroidism 47 abdominally obese 47 unprovoked seizures 47 pathophysiological mechanisms 47 stone formers 47 vitamin B# supplements 47 serum sodium 47 serum BDNF 47 myocardial ischemia 47 prolonged QT interval 47 EGFR mutations 47 arterial stiffness 47 neuropsychiatric disorder 47 brain scans 47 CIN3 47 schizophrenics 47 hyperglycemia 47 PAOD 47 Alzheimer Dementia 47 bone resorption 47 colorectal cancer CRC 47 hydroxyvitamin D 47 euthymic 47 Korsakoff syndrome 47 progressive dyspnea 47 resistant hypertension 47 hyperintense lesions 47 atypia 47 presymptomatic 47 progranulin 47 PNES 47 pathological hallmark 47 cirrhosis 47 diabetic kidney 47 hsCRP 47 generalized seizures 47 klotho 47 activity MAOA 47 cardiovascular disease cerebrovascular disease 47 dietary DHA 47 HIV HCV coinfected 47 comorbidity 47 atherosclerotic disease 47 diabetic nephropathy 47 Hyponatremia 47 haptoglobin 47 STEP BD 47 androgen depletion 47 cerebral microbleeds 47 relapsing MS 47 left ventricular dysfunction 47 cerebrospinal fluid CSF 47 calcitriol 47 aminotransferase levels 47 dietary interventions 47 vertebral fracture 47 AA Amyloidosis 47 syndromal 47 aminotransferases 47 neurological abnormalities 47 homocysteine concentrations 47 hypertensive 47 Subgroup analyzes 47 temper dysregulation disorder 47 AAT deficiency 47 Major depressive disorder 47 WOMAC pain 47 paricalcitol 47 obese 47 2 diabetes T2D 47 PSA velocity 47 ketoacidosis 47 knee osteoarthritis OA 47 aneurysmal subarachnoid hemorrhage 47 Alzheimer Disease Cooperative 47 somatic symptoms 47 antidepressant therapy 47 lipid profiles 47 A1 allele 47 newer antipsychotics 47 BMI z 47 quetiapine Seroquel 47 conventional antipsychotics 47 unipolar depression 47 Dr. Sudha Seshadri 47 gene APOE4 47 essential thrombocythemia 47 asthma exacerbations 47 venous thrombosis 47 serum IGF 47 HbA1c 47 neurobehavioural 47 plasma homocysteine levels 47 clusterin 47 prodrome 47 thyrotoxicosis 47 infantile onset 47 grade dysplasia 47 rheumatoid arthritis RA 47 atopic 47 chronic heartburn 47 OADs 47 pathologic 47 heart disease 47 Myelodysplastic Syndrome MDS 47 autoimmune thyroid 47 cardiometabolic risk 47 autoantibodies 47 irreversible blindness 47 comorbid 47 DCCT 47 Leber congenital amaurosis 47 hyperphosphorylated tau 47 intestinal polyps 47 daytime sleepiness 47 CARDIA 47 apoE4 47 NNT = 47 onset seizures 47 Endothelial function 47 neurologic disorder 47 fasting triglyceride levels 47 teriparatide 47 ADHD symptoms 47 dysfunctional voiding 47 ASDs 47 kidney insufficiency 47 microvascular disease 47 mm Hg systolic 47 serum lipid levels 47 underwent coronary angiography 47 mg dL 47 osteopontin 47 Brodmann Area 47 Prediabetes 47 glomerular filtration 47 hypercalcemia 47 tryptophan depletion 47 GH deficient 47 dysbindin gene 47 candesartan 47 systolic BP 47 artery calcification 47 amenorrhea 47 SOD1 gene 47 familial AF 47 mild renal insufficiency 47 Barrett Esophagus 47 subsyndromal depression 47 hypokalemia hypomagnesemia 47 hyperlipidaemia 47 LVEF 47 Sjögren syndrome 47 severely obese 47 neurodevelopmental outcomes 46 oophorectomy 46 hyperhomocysteinemia 46 magnesium intake 46 adiponectin levels 46 urinary N telopeptide 46 NATRECOR R 46 HPA axis 46 T2 lesions 46 neuronal dysfunction 46 Vitamin B# deficiency 46 psychiatric comorbidities 46 olanzapine 46 #q#.# deletion syndrome 46 migraine sufferers 46 presbyopia 46 lung adenocarcinoma 46 genetic variants 46 index BMI 46 preserved ejection fraction 46 ventricular enlargement 46 advanced neoplasia 46 Posiphen 46 euthyroid 46 pulmonary hypertension PH 46 monoclonal gammopathy 46 habitual snorers 46 allostatic load 46 preserved systolic 46 sinus rhythm 46 anticholinergic medications 46 optic neuropathy 46 galanin 46 artery stenosis 46 amisulpride 46 HGPIN 46 suicidality 46 neurologic 46 dietary supplementation 46 hepatocellular carcinomas 46 Aortic stenosis 46 Generalized Anxiety Disorder 46 tic disorder 46 pathological gambling 46 thyrotropin 46 tibolone 46 glaucomatous 46 THIS STUDY 46 dapagliflozin plus 46 clinically meaningful reductions 46 Genetic variants 46 hyperinsulinemia 46 neovascular form 46 typical antipsychotics 46 transferrin saturation 46 pathophysiologic 46 neurofibrillary 46 Nonalcoholic Fatty Liver Disease 46 calcium supplementation 46 HIV lipodystrophy 46 fructose diet 46 CAG repeats 46 risperidone Risperdal 46 bradykinesia 46 NSTEMI 46 Wernicke encephalopathy 46 intermittent exotropia 46 stable angina 46 nmol L 46 metformin 46 triiodothyronine 46 oral glucose tolerance 46 HOMA IR 46 hemoglobin A1C 46 pre eclampsia 46 Cholinesterase inhibitors 46 NPH insulin 46 hyperthyroidism 46 fructose intolerance 46 prostate carcinogenesis 46 ARVD 46 schizophreniform disorder 46 ApoE 46 leptin deficient mice 46 malignant polyps 46 elevated IOP 46 COREG 46 squamous cell lung cancer 46 somatoform disorders 46 onset diabetes mellitus 46 nonpsychotic 46 CKD 46 muscle dysmorphia 46 untreated obstructive sleep 46 transient ischemic attack 46 nocturia 46 visual acuity 46 mild TBI 46 prefrontal cortical 46 LHON 46 exudative AMD 46 cognitive domains 46 aldehyde dehydrogenase 46 schizophrenia schizoaffective disorder 46 pharmacological therapy 46 ABCB1 46 overnight polysomnography 46 postmenopausal estrogen 46 Study AREDS 46 Wisconsin Sleep Cohort 46 circadian misalignment 46 memantine Namenda 46 FMR1 gene 46 anticholinergics 46 pernicious anemia 46 statin 46 hypoparathyroidism 46 somatization 46 seminoma 46 tau pathology 46 MYH9 gene 46 PTSD symptoms 46 ACh 46 onset atrial fibrillation 46 antihypertensive medications 46 underlying pathophysiology 46 e4 allele 46 Asperger disorder 46 recurrent stroke 46 genetic variations 46 bowel polyps 46 chronic kidney 46 Longitudinal studies 46 EXJADE 46 artery blockages 46 HAQ DI 46 prolactin levels 46 serum parathyroid hormone 46 smoldering myeloma 46 XMRV infection 46 metabolic syndrome clustering 46 opioid dependent 46 gene variants 46 urolithiasis 46 Cognitive 46 Daytime sleepiness 46 extraversion 46 glycosylated hemoglobin HbA1c 46 PICALM 46 cryptogenic 46 manic depressive illness 46 dummy pill 46 elevated uric acid 46 subarachnoid hemorrhage SAH 46 akinetic mutism 46 L thyroxine 46 bile acid metabolism 46 primary hypercholesterolemia 46 pioglitazone 46 folate deficient 46 rhinoconjunctivitis 46 Parkinsonism 46 irregular menstrual cycles 46 DSM IV diagnosis 46 HbA1C 46 severe periodontitis 46 protein tau 46 amyloid beta plaque 46 severe psoriasis 46 FMRP protein 46 Dementia 46 Hypoactive Sexual Desire Disorder 46 liver scarring 46 Moderate drinkers 46 neurodevelopmental impairment 46 thyroid hormone levels 46 EoE 46 hypothalamic amenorrhea 46 Neurology Neurosurgery 46 underactive thyroid 46 Usher Syndrome 46 thrombocytopenic patients 46 hippocampi 46 choroidal vasculopathy 46 endothelial function 46 subconjunctival hemorrhage 46 liver biopsies 46 nontasters 46 autism spectrum disorders ASDs 46 Aß 46 sustained ventricular tachycardia 46 Hurthle cell 46 MDD 46 multivariate adjustment 46 Diabetic neuropathy 46 dysfunction LVSD 46 rs# [004] 46 impulsivity 46 chronic lymphocytic leukemia CLL 46 alcoholic hepatitis 46 chronic renal failure 46 hypoperfusion 46 Grodstein 46 AGILECT R 46 ADAS cog