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(Click for frequent words.) 81 phosphatidylinositol 3 81 ERK1 2 81 extracellular signal 80 catenin 80 serine threonine kinase 80 MAPK 79 MAP kinase 79 phosphorylates 78 receptor tyrosine kinase 78 p# MAPK 78 transcriptional activation 78 IL 1beta 78 Upregulation 78 Phosphorylation 78 serine threonine 78 cell adhesion molecule 77 ß catenin 77 proto oncogene 77 Rap1 77 autocrine 77 IL 1β 77 serine protease 77 proapoptotic 77 TNFalpha 77 E#F# 77 regulated kinase ERK 77 Smad3 77 PDGFR 76 androgen receptor AR 76 NKG2D 76 prostaglandin E2 PGE2 76 ERK pathway 76 c MYC 76 FasL 76 caveolin 76 autophagic 76 EGF receptor 76 caveolin 1 76 Cathepsin B 76 cytokine signaling 76 hypoxia inducible factor 76 protein kinase C 76 p# mitogen activated 76 deacetylation 75 adhesion molecule 75 cytokine receptor 75 regulated kinase 75 kinase pathway 75 VE cadherin 75 Overexpression 75 ERK signaling 75 LRP6 75 Dysregulation 75 tropomyosin 75 lysosomal 75 SIRT2 75 CXCL# 75 H#K# [002] 75 induces apoptosis 75 TGF b 75 tyrosine phosphorylation 75 Rab5 75 acyl CoA 75 phosphate S1P 75 PKC isoforms 75 PI3K Akt 75 MAPK pathway 75 N methyl 75 activin 75 downstream effector 75 heterodimers 75 mediated apoptosis 75 Clusterin 75 c MET 75 oncoprotein 75 dephosphorylation 75 prolyl 75 VEGF receptor 75 Oncogenic 75 homodimers 74 proteolysis 74 Akt activation 74 LDL receptor 74 tumor suppressor protein 74 mRNA expression 74 peroxisome proliferator activated 74 FGFR3 74 eNOS 74 mediated inhibition 74 downregulates 74 oxidase 74 neurite outgrowth 74 acetylcholine receptor 74 Macrophage 74 STAT1 74 cyclooxygenase COX 74 transactivation 74 phosphoprotein 74 pRb 74 TGF ß 74 ubiquitination 74 potent inhibition 74 HIF 1alpha 74 cAMP signaling 74 intracellular signaling 74 uPAR 74 cell adhesion molecules 74 transcriptional repressor 74 estrogen receptor alpha 74 constitutively expressed 74 Cdc# 74 MEK1 74 NF κB 74 histone deacetylases 74 E3 ligase 74 V#F mutation 74 β catenin 74 decarboxylase 74 protein tyrosine phosphatase 1B 74 glucocorticoid receptor 74 hydroxylase 74 protein tyrosine kinase 74 Interferon gamma 74 cytosolic 74 γ secretase 74 glucokinase 74 c Src 74 Fas ligand 74 kinase PI3K 74 NFAT 74 cyclooxygenase 2 74 downregulation 74 transcriptional regulation 74 RAS RAF MEK 74 JAK STAT 74 p#Kip# 74 Protein Kinase C 74 paracrine 74 TGF beta1 74 Nedd4 74 cyclooxygenase 73 ubiquitylation 73 HIF 1α 73 antiapoptotic 73 DNMT1 73 retinoic acid receptor 73 NFκB 73 receptor subtype 73 guanosine 73 selective inhibition 73 upregulation 73 RhoA 73 ENaC 73 Rac1 73 NFkappaB 73 Akt signaling 73 paxillin 73 synthetase 73 5 lipoxygenase 73 aberrantly activated 73 JAK2 enzyme 73 c myc 73 proinflammatory 73 tyrosine kinase 73 carcinoembryonic antigen 73 pathophysiological effects 73 induced apoptosis 73 overactivation 73 monocyte 73 IL 1ß 73 cyclin dependent kinase 73 Wnt beta catenin 73 constitutively active 73 cyclin D1 73 ERBB2 73 PPARgamma 73 Hedgehog signaling 73 sphingosine 1 73 chemokine receptor 73 matrix metalloproteinase 73 vimentin 73 mitogen activated protein 73 tyrosine kinase receptor 73 MMP2 73 eIF4E 73 ectopic expression 73 4E BP1 73 ERK1 73 methyl D aspartate 73 NFkB 73 hepatocyte growth 73 proteolytic cleavage 73 phosphatases 73 inducible nitric oxide synthase 73 downregulated 73 HepG2 cells 73 iNOS 73 lipoxygenase 73 ubiquitin ligase 73 histone acetylation 73 adenylate cyclase 73 reductase 72 dimerization 72 PAK1 72 mitogenic 72 polyamine 72 cytochrome P# 72 cholecystokinin CCK 72 microglial activation 72 cyclins 72 PGC 1α 72 apoptotic pathway 72 factor HGF 72 alpha subunit 72 downregulating 72 cytochrome c 72 PPARg 72 IL #p# 72 costimulatory 72 superoxide dismutase 72 CD#b 72 ubiquitinated 72 ERalpha 72 K + ATPase 72 muscarinic receptors 72 cell motility 72 kinase domain 72 Rho kinase 72 p# activation 72 phosphatase 72 Rho GTPase 72 heme oxygenase 72 upregulates 72 Akt 72 matrix metalloproteinases MMPs 72 cystic fibrosis transmembrane conductance 72 mitogen activated protein kinases 72 muscarinic 72 hydrolase 72 TNFR 72 TGF β 72 glycolipids 72 beta amyloid peptide 72 TNF receptors 72 GLI1 72 Runx2 72 Nampt 72 GTPase 72 TGF alpha 72 adrenoceptor 72 receptor kinase 72 transferase 72 PI3K pathway 72 Hypoxia Inducible Factor 72 5 HT1A 72 E cadherin 72 anti apoptotic 72 constitutive activation 72 HDAC2 72 oxidative phosphorylation 72 NF KappaB 72 NF kappaB 72 HIF 1a 72 synuclein 72 myocyte enhancer factor 72 RUNX3 72 cathepsins 72 TSC1 72 hydrolases 72 isoenzyme 72 leukocyte adhesion 72 cyclin dependent kinases 72 intercellular adhesion molecule 72 Tumor necrosis factor 72 TrkB 72 TRAIL induced apoptosis 72 neuronal dysfunction 72 Arp2 3 72 antiproliferative activity 72 VEGFR2 72 Activating mutations 72 CagA 72 somatostatin 72 Secretase 72 endoplasmic reticulum stress 72 cyclic adenosine monophosphate cAMP 72 Histone 72 LKB1 72 PTPN# 72 MAP kinase pathway 72 Skp2 72 BMP2 72 Vascular endothelial growth 72 thioredoxin 72 JNK1 72 phospho 72 protein encoded 72 Src 72 nAChRs 72 ADAM# 72 prostaglandin synthesis 72 transmembrane protein 72 ERa 72 TORC2 72 hypermethylation 72 upregulated 71 Factor VEGF 71 oncogenic 71 cyclic AMP cAMP 71 FGF receptor 71 phosphorylated 71 BMAL1 71 FOXO3a 71 oligomerization 71 receptor gamma 71 MAP kinases 71 mTOR signaling 71 thyroid hormone receptor 71 selectively inhibits 71 Î ² 71 receptor mediated endocytosis 71 nAChR 71 mTOR mammalian target 71 phosphatidylinositol 71 #HT#A 71 Src kinase 71 IFN γ 71 IGF1R 71 neurofilament 71 enzymatic activity 71 histone H3 71 HOTAIR 71 LPS induced 71 neuronal differentiation 71 PI3K/Akt 71 thrombin receptor 71 BCL2 71 tau phosphorylation 71 secretase 71 diphosphate 71 TNF α 71 PHD2 71 secretory pathway 71 casein kinase 71 adrenergic receptors 71 HER2 HER3 71 isoenzymes 71 FGFR 71 T#M 71 NMDA N 71 HER2 HER2 71 glycosylated 71 COX2 71 dimeric 71 AhR 71 selective modulator 71 phosphorylation 71 IRE1 71 potent inhibitors 71 adipogenic 71 apoE 71 glucose transporter 71 tyrosine kinases 71 triggers apoptosis 71 beta subunit 71 cyclin dependent kinase inhibitor 71 IL6 71 immunoreactivity 71 interleukins 71 AgRP 71 IGFBP2 71 cAMP 71 cytoplasmic domain 71 adipogenesis 71 tyrosine hydroxylase 71 subcellular localization 71 proinflammatory cytokines 71 MDM2 71 Aβ 71 pleiotropic 71 costimulation 71 matrix metalloproteinases 71 fibrogenesis 71 RANK ligand 71 receptor molecule 71 acinar 71 thrombospondin 71 LRP5 71 upregulating 71 HDACs 71 vascular endothelial cells 71 C5aR 71 renal fibrosis 71 H#K#me# 71 ErbB4 71 triphosphate 71 D aspartic acid 71 glycosyltransferase 71 CCR2 71 evolutionarily conserved 71 Notch receptor 71 pro apoptotic 71 telomerase reverse transcriptase 71 cytokine receptors 71 phosphoinositide 71 TGFβ 71 sphingolipid 71 induce apoptosis 71 Factor Receptor 71 regulator CFTR protein 71 1beta 71 FGFR1 71 activating mutations 71 clusterin 71 prostaglandin E2 71 lipopolysaccharide 71 lyase 71 acetylation 71 CCL# 71 signaling cascades 71 Tie2 71 CYP#B# 71 Notch1 71 synaptogenesis 71 monocyte chemotactic protein 71 focal adhesion kinase FAK 71 receptor subtypes 71 Foxp3 71 oligomeric 71 postsynaptic 71 RANKL 71 WT1 71 phagocytosis 71 neuropeptide Y 71 vascular endothelial 71 anti inflammatory cytokine 71 endothelial nitric oxide synthase 71 astrocytic 70 glycogen synthase kinase 70 calpain 70 cyclic nucleotide 70 metalloproteinase 70 PTHrP 70 erythroid 70 Aldosterone 70 related apoptosis inducing 70 virulence genes 70 actin polymerization 70 eotaxin 70 Ca2 + 70 STAT3 70 HMG CoA reductase 70 Catenin 70 cytidine 70 histone methyltransferase 70 secreted protein 70 BMP signaling 70 cAMP dependent 70 5' monophosphate 70 interleukin IL -# 70 Caspase 70 cathepsin B 70 tubulin 70 protein phosphatase 70 Monocyte 70 p# MAP kinase 70 glutamate receptors 70 GSTP1 70 basolateral 70 Brain derived neurotrophic 70 microglial 70 Kv#.# 70 phospholipase 70 homodimer 70 Wnt signaling 70 ERK phosphorylation 70 transmembrane receptor 70 PI3 kinase 70 receptor alpha 70 SCD1 70 sortilin 70 F actin 70 CCL2 70 SOD1 70 intracellular proteins 70 encodes protein 70 RANTES 70 GAPDH 70 elastase 70 constitutively 70 tyrosine 70 KLF4 70 AT1R 70 PTP 1B 70 chemokine 70 GABAA receptors 70 FGFs 70 exocytosis 70 dioxygenase 70 HBx 70 heme oxygenase 1 70 MEK ERK 70 secretory 70 potent inhibitor 70 CaM 70 cyclic AMP 70 Lyn kinase 70 TIMP 70 hepatic lipase 70 poly ADP ribose polymerase 70 receptor mediated 70 MAPKs 70 SGK1 70 selectively inhibited 70 Janus kinase 70 Smad 70 protein kinases 70 ER alpha 70 TSLP 70 B lymphocyte stimulator 70 Epithelial 70 Angiotensin II 70 neuropeptide Y NPY 70 phospholipase A2 70 cadherin 70 CYP#A# CYP#D# 70 1α 70 IFN gamma 70 COL#A# 70 #ß 70 gene polymorphisms 70 ERK 70 Aurora kinase 70 UCP2 70 regulating gene expression 70 CDK5 70 endocytic 70 TGF beta pathway 70 signaling pathway 70 Sgk1 70 cell adhesion 70 fast skeletal troponin 70 podocyte 70 SGLT2 70 nucleolin 70 syntaxin 70 Angiotensin converting enzyme 70 melanocyte 70 immunostimulatory 70 PPARγ 70 peroxidase 70 GRP# 70 acyltransferase 70 nitric oxide synthase 70 alpha TNFa 70 receptor activation 70 MyD# 70 E3 ubiquitin ligase 70 Th2 70 serotonin receptor 70 beta catenin 70 tumorigenesis 70 prostaglandin E 70 colocalization 70 catalytic subunit 70 MMP9 70 DNA intercalator 70 IKKß 70 TRPV3 70 osteoblast 70 Cyclin E 70 amyloid ß 70 glucocorticoid receptors 70 5 HT2A receptor 70 NKX#.# 70 presynaptic 70 EphA2 70 FLT3 70 cyclin E 70 NF kappaB activation 70 SMAD4 70 Kupffer cells 70 inverse agonist 70 potent inducer 70 CD1d 70 CEACAM1 70 proteoglycan 70 GNAQ 70 axon guidance 70 mitochondrial respiration 70 metalloprotease 70 TMEM#B 70 basophils 70 FKBP# 70 mitotic progression 70 brain derived neurotrophic 70 phosphoinositide 3 70 dopamine D2 70 downstream effectors 70 adipokines 70 5 HT2A serotonin 70 apoptotic 70 functional polymorphism 70 Notch signaling 70 Cyclin D1 70 Mcl 1 70 neurofibromin 70 PAR1 70 Cytochrome P# 69 TORC1 69 acetylcholinesterase 69 BACE1 69 tRNA synthetase 69 genes encoding 69 transmembrane domains 69 PIP3 69 tensin homolog 69 ATPase 69 M1 muscarinic 69 peroxisomal 69 demethylase 69 β1 69 protein kinase 69 vacuolar 69 uracil 69 cytochrome P 69 GSK3 69 Aß 69 69 HER3 69 protein tyrosine phosphatase 69 estrogen receptor beta 69 PIP2 69 nitric oxide synthase NOS 69 chemokine receptors 69 DNA methyltransferases 69 GluR1 69 P2X 69 ACh 69 inducible 69 bradykinin 69 Leukotrienes 69 adipokine 69 MMP7 69 serine proteases 69 EF Tu 69 tumor suppressive 69 neuromuscular junction 69 inflammatory cytokine 69 CXCR2 69 NF kappaB pathway 69 Wnt 69 gene encodes 69 SIRT3 69 CTGF 69 FOXO 69 proximal tubule 69 p# alpha [001] 69 isoforms 69 p#NTR 69 acetyl CoA 69 pyrimidines 69 S1P 69 succinate dehydrogenase 69 LNCaP cells 69 transferrin receptor 69 dehydrogenases 69 effector function 69 Sp1 69 P selectin 69 alpha#beta# 69 adipocyte 69 Flt3 69 effector cells 69 modulatory 69 cellular pathways 69 E selectin 69 ß1 69 H#K# [001] 69 VEGFR1 69 heterodimer 69 NF kB pathway 69 intestinal epithelial cells 69 anaphase promoting complex 69 demethylation 69 FGFR2 69 transcriptional repression 69 HDAC6 69 aryl hydrocarbon receptor 69 cholesterol homeostasis 69 Tumor Necrosis Factor 69 1alpha 69 enkephalin 69 PC# cells 69 phosphorylate 69 Rho GTPases 69 RAR beta 69 EGFr 69 PGE2 69 interferon γ 69 glutamate receptor 69 chemoattractant 69 HDAC enzymes 69 osteopontin 69 uM 69 TAp# 69 esterase 69 transduced 69 ABCA1 69 lymphotoxin 69 glutamyl 69 Vps# 69 BMP4 69 monocytes macrophages 69 hypothalamic pituitary adrenal axis 69 pDC 69 nicotinic acetylcholine receptor 69 underlying vasculopathy 69 PPAR gamma 69 extracellular domain 69 isotypes 69 proteolytic 69 TSP1 69 TLR2 69 mediated phosphorylation 69 protein tyrosine phosphatases 69 Aâ 69 Protein kinase 69 receptor CXCR4 69 c Myc 69 cofilin 69 copper zinc superoxide 69 vWF 69 PLA2 69 AMPA receptor 69 histone deacetylase 69 cysteine residues 69 colorectal carcinoma 69 Mutational 69 phosphate dehydrogenase 69 BCR ABL 69 Bcl XL 69 MTHFR 69 coactivator 69 glial 69 hypothalamic pituitary 69 polyamines 69 plasmacytoid dendritic cells 69 nNOS 69 RRM1 69 Wnts 69 epithelia 69 NMDA receptor 69 opioid receptor 69 Galectin 69 endocytosis 69 retinoid X 69 NOD2 69 matrix metalloproteases 69 noradrenergic 69 NF kappa B 69 NAD + 69 lymphocyte activation 69 glucagon receptor 69 EGFR signaling 69 intestinal epithelium 69 ribosomal protein 69 PML RARA 69 p# p# 69 caspase activation 69 Smurf1 69 transient receptor 69 NADPH 69 PDGF receptor 69 morphogen 69 WNK1 69 posttranslational modifications 69 monomeric 69 TGF ß1 69 STAT3 signaling 69 TGF β1 69 survivin 69 NADPH oxidase 69 HER2 neu 69 siRNA mediated 69 transcriptionally 69 carboxyl terminal 69 FOXP3 69 factor kappa B 69 endogenous ligands 69 BRAF V#E 69 inhibitory effects 69 colony stimulating factor 69 Eg5 69 granzyme B 69 ErbB 69 metabolizing enzyme 69 PGC1 69 actin cytoskeleton 69 pro angiogenic 69 E cadherin expression 69 osteoclast activity 69 messenger ribonucleic acid 69 HER1 69 adrenal cortex 69 amyloid β 69 beta arrestin 68 GABA receptor 68 TIMP 1 68 RANK Ligand 68 interleukin 1beta 68 GABAergic 68 Cytotoxic T 68 adenosine diphosphate ADP 68 Jhdm2a 68 Protein Kinase 68 Wnt signaling pathway 68 lysine residues 68 D aspartate 68 overexpressing 68 cytochrome 68 pro inflammatory cytokine 68 cyclin dependent kinases CDKs 68 monocyte chemoattractant protein 68 Fibroblast Growth Factor Receptor 68 keratinocyte 68 eicosanoid 68 osteocalcin 68 synthase 68 SH2 domain 68 CD4 + CD# 68 Th1 type 68 Extracellular 68 TrkA 68 5 HT1A receptor 68 c KIT 68 ganglioside 68 osteogenic differentiation 68 lysyl oxidase 68 cytolytic 68 gamma secretase 68 VIPR2 68 ouabain 68 anterior pituitary 68 cyclin B1 68 CaMKII 68 mineralocorticoid receptor 68 glomerular 68 Polymorphisms 68 dehydrogenase 68 transgene expression 68 regulates gene expression 68 methyltransferase 68 circadian clock genes 68 promoter methylation 68 peptide CGRP 68 PON1 68 hTERT 68 miR #a [002] 68 signaling cascade 68 EphB4 68 cyclic adenosine monophosphate 68 cytokine secretion 68 excitatory neurotransmitter glutamate 68 SUMOylation 68 epigenetic silencing 68 thymidine 68 glutamatergic 68 rRNA 68 miR #b [002] 68 EZH2 68 lymphangiogenesis 68 calcineurin 68 TGF beta 68 IGFBP 68 presenilin 68 CD# ligand 68 metabolic enzymes 68 PDE1 68 PDGFR alpha 68 endosomal 68 p# subunit 68 Th1 cells 68 pharmacological inhibition 68 MT1 MMP 68 aminobutyric acid 68 Stat3 68 isomerase 68 isoleucine 68 uPA 68 allosteric 68 signaling molecule 68 Htt 68 myeloid 68 tryptase 68 Integrin 68 transcriptional regulators 68 MDR1 68 Androgen receptor 68 metalloproteases 68 dependent protein kinase 68 cysteine protease 68 KLF2 68 inhibitory 68 Epidermal Growth Factor Receptor 68 histone H4 68 Caveolin 1 68 glyceraldehyde 3 68 ErbB receptors 68 melatonin receptor 68 CDK inhibitor 68 TNFα 68 TTR gene 68 endogenous ligand 68 GSK 3ß 68 transcription factor 68 urocortin 68 palmitate 68 NF kB 68 hyperactivation 68 CCR7 68 lymphoid 68 Ang2 68 GLUT1 68 c Myb 68 pyrimidine 68 erythrocytes 68 chromatin structure 68 biogenesis 68 S nitrosylation 68 Nod1 68 RAF kinase VEGFR 68 S#A# [002] 68 thromboxane A2 68 c Fos 68 glutathione S transferase 68 β2 68 KIAA# 68 beta actin 68 PDE#A 68 hypermethylated 68 constitutively activated 68 avidin 68 PI3K AKT 68 NR2B 68 PEDF 68 S#P# 68 receptors EGFR 68 selectively binds 68 calcitonin gene related 68 synaptic vesicle 68 cystic fibrosis transmembrane 68 signal transduction 68 miR #a [001] 68 focal adhesions 68 Signal transduction 68 cotransporter 68 phospholipase C 68 topoisomerase II 68 RIP1 68 cyclase 68 receptor gene 68 receptors PPARs 68 mTOR 68 PI3K/AKT 68 centromeric 68 transcription factors 68 proteinase 68 superoxide dismutase SOD 68 leucine zipper 68 MyoD 68 FGF2 68 LPA1 receptor 68 interleukin IL 68 histone methylation 68 synapse formation 68 potently inhibits 68 acetyltransferase 68 SMase 68 Immunohistochemical analysis 68 gamma aminobutyric acid 68 bile acid 68 thymidylate synthase TS 68 neutrophil elastase 68 β 68 bcl 2 68 cytoskeletal 68 N cadherin 68 RTKs 68 oncogenic transformation 68 oncoproteins 68 somatostatin receptors 68 epithelial mesenchymal transition 68 AMACR 68 LIS1 68 ligand TRAIL 68 oxidases 68 synaptic transmission 68 Selective Inhibitor