Related by context. All words. (Click for frequent words.) 79 tau protein 75 protein tau 75 senile plaques 74 amyloid beta plaques 74 beta amyloid peptide 74 beta amyloid plaques 74 amyloid plaques 73 amyloid deposits 73 Amyloid plaques 73 β amyloid 72 tau proteins 72 Lewy bodies 71 amyloid beta peptides 71 amyloid plaque 71 Amyloid beta 71 amyloid beta protein 70 protein beta amyloid 70 beta amyloid peptides 70 amyloid ß 70 lipofuscin 69 neuronal cell 69 beta amyloid protein 69 pathological hallmark 69 amyloids 69 Aß 69 phosphorylated tau 69 demyelination 69 amyloid protein 69 neuronal dysfunction 69 neuritic plaques 69 beta amyloid 69 beta amyloid proteins 69 amyloid peptides 68 protein alpha synuclein 68 Aβ 68 amyloid proteins 68 amyloid beta peptide 68 fibrous tangles 68 Beta amyloid 68 tau tangles 68 abnormal clumps 68 Abeta# 68 Alzheimer pathology 68 toxic amyloid beta 68 protein clumps 68 amyloid peptide 68 progranulin 68 amyloid beta 67 amyloid beta proteins 67 alpha synuclein 67 beta amyloid plaque 67 serine protease 67 ADDLs 67 protein kinase C 67 hyperphosphorylation 67 alpha synuclein protein 67 amyloid β 66 LDL receptor 66 LRP6 66 sporadic ALS 66 Abeta 66 apoE 66 insoluble plaques 66 beta amyloid fragments 66 SIRT3 66 microglial 66 clusterin 66 COX enzymes 66 γ secretase 66 ß amyloid 66 TMEM#B 66 oligomeric 66 excitatory neurotransmitter glutamate 66 gliosis 66 synaptic function 65 ERK1 2 65 misfolded 65 amyloid 65 chromosomal instability 65 Aâ 65 toxic beta amyloid 65 tumor suppressor protein 65 BACE1 65 huntingtin protein 65 PTPN# 65 motor neuron degeneration 65 insoluble protein 65 misfolded proteins 65 antioxidant enzyme 65 synuclein 65 Amyloid 65 mutant protein 65 matrix metalloproteinases 65 ERK signaling 65 abnormal proteins 64 glycolipids 64 apoE4 64 SOD1 64 Oxidative stress 64 Aβ# 64 autophagic 64 Skp2 64 endoplasmic reticulum stress 64 caspase activation 64 microglial activation 64 mitogen activated protein kinase 64 Alu RNA 64 gamma secretase 64 neurodegeneration 64 proto oncogene 64 PHD2 64 acyl CoA 64 FTLD 64 secretase 64 sphingolipid 64 glutamate receptors 64 retinoid X 64 micro RNAs 64 non coding RNA 64 FGFR3 64 renal fibrosis 64 MAP kinase 64 TET2 64 amyloid fibrils 64 tau protein tangles 64 cell adhesion molecule 64 synaptogenesis 63 PDGFR 63 amyloid precursor protein 63 fatty acid oxidation 63 Cyclin D1 63 superoxide 63 BRAF protein 63 superoxide dismutase 63 hyperphosphorylated tau 63 polyamines 63 nitric oxide synthase 63 ankyrin B 63 osteopontin 63 cardiolipin 63 ACh 63 cerebrospinal fluid CSF 63 neurofibrillary 63 lipid peroxides 63 pRb 63 ABCA1 63 protein fragment 63 mutant huntingtin 63 tau aggregates 63 epigenetic modification 63 miRNA genes 63 receptor subtype 63 telomere dysfunction 63 vimentin 63 Upregulation 63 oligomers 63 MAPK pathway 63 GPR# [002] 63 LIS1 63 Clusterin 63 NADPH oxidase 63 presenilin 63 cell adhesion molecules 63 neuroligins 63 amyloid deposition 63 matrix metalloproteinases MMPs 63 naturally occurring neuroprotective 63 excitotoxicity 63 PGC 1α 63 antiapoptotic 63 glucocerebroside 63 CHD7 63 STAT4 63 misfolded protein 63 intestinal epithelium 63 progranulin protein 63 potent inhibitors 63 redox active 63 Cathepsin B 63 sortilin 63 progerin 63 mutated protein 63 mitochondrial respiration 63 transthyretin 63 5 lipoxygenase 62 androgen receptor AR 62 LRP5 62 neuropathological 62 ptau 62 Wnt signaling pathway 62 glomerular 62 myo inositol 62 activated microglia 62 FGF2 62 tetramer 62 desmin 62 neuronal degeneration 62 factor HGF 62 NFTs 62 peroxisomal 62 CYP#B# 62 catenin 62 potent inhibition 62 α synuclein 62 CXCL# 62 cellular metabolism 62 Smad3 62 fibrillar 62 amyloid protein plaques 62 podocyte 62 myeloid 62 FGFR1 62 pyrimidines 62 TGF β 62 receptor gamma 62 abnormal prion protein 62 MDM2 62 BMP signaling 62 abnormal tau 62 myofibroblasts 62 macrophage infiltration 62 TSC1 62 tau 62 selective inhibition 62 GPIHBP1 62 Amyloid beta protein 62 ganglioside 62 PIP3 62 vWF 62 podocytes 62 p# activation 62 serine threonine 62 syntaxin 62 DNMT1 62 Wnt signaling 62 fatty acid synthase 62 IL #p# 62 EZH2 62 leukocyte adhesion 62 Smad7 62 Overexpression 62 uPAR 62 activin 62 genomic instability 62 Amyloid Beta 62 neurite outgrowth 62 huntingtin 62 familial ALS 62 microcephalin 62 glial 62 H#K#me# 62 KIAA# 62 triphosphate 62 hepatocyte growth 62 underlying vasculopathy 62 MLH1 62 Hsp# [001] 62 Abeta protein 62 lipoxygenase 62 perivascular 62 systemic inflammation 62 proteoglycan 62 adrenal cortex 62 #ß 62 oxidases 62 nAChR 62 NMDA receptors 62 enzymatic activity 62 MAP kinases 62 substantia nigra 62 homeobox gene 62 osteoclast 62 SHANK3 62 GSK3 61 β catenin 61 mutant huntingtin protein 61 goblet cells 61 resistin 61 nNOS 61 Eg5 61 c MET 61 beta secretase 61 vascular endothelial cells 61 IL 1beta 61 epigenetic alterations 61 osteocalcin 61 UCP1 61 dimeric 61 airway remodeling 61 c MYC 61 JAK2 enzyme 61 osteoblastic 61 miR #a [002] 61 PML RARA 61 chromosomal rearrangement 61 Huntingtin 61 Misfolded proteins 61 metalloproteinases 61 NR2B subunit 61 CB2 receptor 61 cyclin E 61 amyloid plaque formation 61 proteolysis 61 regulated kinase ERK 61 phagocytosis 61 mitochondrial dysfunction 61 4E BP1 61 enzyme beta secretase 61 nucleoli 61 Pten 61 caveolin 1 61 fibrotic 61 RANKL 61 systemic amyloidosis 61 p# MAPK 61 BRAF gene 61 ADAM# 61 MT1 MMP 61 Wnt pathway 61 transgenic mouse models 61 overactivation 61 eotaxin 61 adhesion molecule 61 tenascin C 61 MMP# 61 factor BDNF 61 hepatic lipase 61 microglial cells 61 myelofibrosis polycythemia vera 61 Macrophage 61 TGF beta 61 c myc 61 missense mutations 61 neuromuscular junction 61 Runx2 61 ribosomal proteins 61 neurotransmission 61 transcriptional repressor 61 advanced glycation end 61 TSLP 61 TGF beta pathway 61 frataxin 61 frontotemporal dementia 61 parkinsonism 61 F actin 61 microtubule dynamics 61 Hypoxia Inducible Factor 61 FGFs 61 cystine 61 Aß# 61 p tau 61 acetylcholine receptor 61 SCD1 61 Alzheimer disease pathology 61 cAMP signaling 61 lysosomal 61 conductance regulator 61 amyloid β peptide 61 NMDA receptor 61 subcortical 61 glycosylated 61 carcinoembryonic antigen 61 LKB1 61 aldehyde dehydrogenase 61 MMP2 61 essential thrombocythemia 61 E3 ligase 61 protein tyrosine phosphatase 1B 61 glutamatergic 61 phosphorylates 61 protein tyrosine phosphatase 61 acetylcholinesterase AChE 61 histone modifications 61 PON1 61 prostaglandin E2 61 adipogenic 61 TGF ß 61 plasminogen 61 Monocyte 61 TGF b 61 caveolin 61 TSP1 61 reductase 61 dysregulated 61 endogenous ligands 61 cohesin 61 PTEN gene 61 biochemical abnormalities 61 SMN protein 61 proinflammatory cytokines 61 Insulin resistance 61 nicotinic receptors 61 dopamine transporter 61 lymphocyte activation 61 encodes protein 61 serotonin receptor 61 purines 61 exocrine 61 E cadherin 61 protein misfolding 61 ApoE4 61 thyrotropin 61 GABAergic interneurons 61 axonal damage 61 transmembrane domains 61 SORL1 61 brain derived neurotrophic 61 beta catenin 60 HFE gene 60 WNK1 60 amyloid beta plaque 60 TGF ß1 60 HDACs 60 presynaptic 60 TGF beta1 60 HDAC2 60 tyrosine 60 beta catenin protein 60 engineered RAP peptides 60 basal ganglia 60 MECP2 gene 60 acinar 60 anti inflammatory cytokine 60 histone methylation 60 neurotransmitter glutamate 60 intermediate filaments 60 inflammatory cytokines 60 peroxynitrite 60 NF κB 60 ERK pathway 60 deacetylation 60 neuropathologic 60 morphogen 60 tyrosine phosphorylation 60 hypermethylation 60 IL 1ß 60 phosphatidylinositol 3 60 Amino acid 60 CALHM1 60 adipogenesis 60 inducible nitric oxide synthase 60 neurexins 60 TTR gene 60 disulfide bond 60 5 HT1A 60 endothelial activation 60 Hedgehog signaling 60 lymphoid tissue 60 uPA 60 Beta Amyloid 60 von Willebrand factor 60 GSTP1 60 galanin 60 ubiquitinated 60 interleukins 60 caspases 60 cystic fibrosis transmembrane conductance 60 retinoic acid 60 lipoprotein lipase 60 tau pathology 60 neuronal signaling 60 apoptotic pathway 60 p# mutations 60 gamma aminobutyric acid 60 synthetase 60 protein CETP 60 Prion diseases 60 GSTT1 60 cytokine receptor 60 DLX5 60 paralogs 60 Hedgehog pathway 60 paxillin 60 acetylcholine 60 neuron degeneration 60 Uric acid 60 SOD1 protein 60 phosphate S1P 60 ciliated 60 secreted protein 60 astrocytic 60 60 ectoderm 60 T#M 60 AhR 60 tubule 60 globin 60 ENaC 60 noradrenergic 60 S#A# [002] 60 mevalonate 60 metalloproteases 60 PPARγ 60 Brain derived neurotrophic 60 hydrolases 60 MAPK 60 IDH1 60 chromatin structure 60 axon guidance 60 gastric carcinogenesis 60 histone deacetylation 60 alpha synuclein gene 60 RAS RAF MEK 60 osteoclast activity 60 GNAQ 60 carbohydrate metabolism 60 estrogen receptor alpha 60 NR#A# 60 pressure natriuresis 60 tyrosine hydroxylase 60 palladin 60 bile acid 60 tyrosine kinases 60 MSH2 60 osteoblast 60 beta amyloids 60 leukotrienes 60 lymphoid 60 malignant transformation 60 uric acid 60 PDE#A 60 thioredoxin 60 sphingolipids 60 SIRT1 gene 60 V#F mutation 60 androgen receptors 60 Dysregulation 60 serotonin synthesis 60 ependymal cells 60 IGFBP2 60 focal adhesion kinase FAK 60 metalloproteinase 60 myelination 60 HOTAIR 60 Mcl 1 60 myoepithelial 60 frontotemporal 60 synapse formation 60 dysregulation 60 metabolic abnormalities 60 #beta HSD1 60 PrPC 60 autocrine 60 eNOS 60 cerebellar 60 calcium oxalate 60 transmembrane protein 60 dynamin 60 Leydig cell 60 proteolytic cleavage 60 Amyloid Precursor Protein 60 mRNA expression 60 atherosclerotic plaques 60 protein kinases 60 acetyl groups 60 ceramide 60 DNA methyltransferase 60 postsynaptic 60 RBP4 60 VEGF receptor 60 vacuoles 60 BARD1 60 aggregated Abeta 60 COX2 60 MTHFR 60 PKC enzyme 60 protein tangles 60 FKBP# 60 hyperactivation 60 eosinophils 60 KLF4 60 Activating mutations 60 cell motility 60 aggrecan 60 nAChRs 60 amyloid fibers 60 GluR1 60 extracellular signal 60 pyrimidine 60 LRRK2 60 Lrp5 59 FGF# 59 neuroligin 59 intracellular signaling 59 Arp2 3 59 SGK1 59 aromatase 59 tumoral 59 nitrotyrosine 59 chylomicrons 59 procaspase 3 59 beta1 integrin 59 porphyrins 59 Fibroblasts 59 endothelial nitric oxide 59 neuroinflammation 59 nerve degeneration 59 synthases 59 fatty acid synthesis 59 ERK1 59 amnestic mild cognitive impairment 59 Hashimoto thyroiditis 59 tauopathies 59 PI3K pathway 59 isoenzymes 59 excitotoxic 59 FUS1 59 EP1 receptor 59 Cyclin E 59 FDDNP 59 mucins 59 phosphatases 59 MMPs 59 LRAT 59 dopamine signaling 59 cathepsins 59 neurotransmitter acetylcholine 59 UCP2 59 soluble beta amyloid 59 VIPR2 59 synovial cells 59 invadopodia 59 kappa opioid receptors 59 vascular endothelial 59 missense mutation 59 oxidized lipids 59 histone 59 matrix metalloproteases 59 ORMDL3 59 pathophysiological effects 59 PICALM 59 DISC1 59 anti apoptotic 59 serine proteases 59 cyclin 59 laforin 59 glycosylation 59 gamma aminobutyric acid GABA 59 BCL2 59 angiotensinogen 59 TNFalpha 59 hydrolase 59 proinflammatory 59 neuroinflammatory 59 receptor gene 59 lipid peroxidation 59 alpha MSH 59 mitochondrial enzyme 59 SIRT1 protein 59 NKG2D 59 Abeta peptide 59 metabolic enzymes 59 Kupffer cells 59 alpha Gal 59 transgenic mouse model 59 adenylate cyclase 59 ubiquitin ligase 59 paracrine 59 IL 1β 59 TORC1 59 copper zinc superoxide 59 anthocyanidins 59 micro RNA 59 Prox1 59 TRPV1 receptors 59 interstitial fibrosis 59 P. gingivalis 59 cdk5 59 NFAT 59 fibrils 59 PLA2 59 cyclic adenosine monophosphate cAMP 59 related apoptosis inducing 59 atherosclerosis 59 FGFR2 59 bone resorption 59 Factor VEGF 59 costimulatory 59 endoxifen 59 dendritic spines 59 GPx 59 senescent cells 59 neurotrophic 59 BMP4 59 oncoprotein 59 miR #a [001] 59 histone deacetylases 59 acetyl CoA 59 mutant proteins 59 cytochrome c 59 DNA adducts 59 genes encode proteins 59 phenylalanine 59 GATA4 59 casein kinase 59 hepatic glucose production 59 filaggrin 59 mediated inhibition 59 Integrin 59 K ras mutations 59 erythropoiesis 59 endogenous cannabinoids 59 matrix metalloproteinase 59 chemokine receptor 59 tumor suppressor gene 59 CDK5 59 telomere maintenance 59 locus coeruleus 59 micronuclei 59 DNA methyltransferases 59 cytoplasmic domain 59 Dr. Bezprozvanny 59 focal adhesions 59 Purkinje cells 59 proteolytic enzymes 59 exocytosis 59 Phosphorylation 59 caveolae 59 JAK2 59 myeloid derived 59 reactive oxygen species 59 gastric carcinoma 59 CaM kinase II 59 acetylation 59 NKX2 59 cytokine signaling 59 endonuclease 59 decarboxylase 59 parkin gene 59 necrotic core 59 cellular pathways 59 EphB2 59 hyperinsulinemia 59 prostaglandin synthesis 59 reactive oxygen species ROS 59 ERK2 59 induce apoptosis 59 granzyme B 59 LDLs 59 Notch signaling 59 cytoskeletal 59 microglia 59 amyloidogenic 59 ubiquitylation 59 KCNQ1 59 glucokinase 59 Kv#.# 59 coronary plaques 59 subventricular zone 59 arachidonic acid 59 tRNA synthetase 59 upregulates 59 Alpha synuclein 59 posttranslational modification 59 mGluR2 NAM 59 Notch receptor 59 vascular inflammation 59 proapoptotic 59 soluble fms 59 amyloid â 59 induces apoptosis 59 anterior pituitary 59 acylated 59 genotoxic stress 59 xanthine 59 brain lesions 59 misfolding 59 epigenetic silencing 59 DGAT1 59 neuropeptide Y NPY 59 ADAMTS# 59 Dpp 59 Rab5 59 gene p# 59 abnormal angiogenesis 59 ectopic expression 59 VE cadherin 59 Fas ligand 59 proinsulin 59 E selectin 59 genetic polymorphism 59 apoC III 59 ADPKD 59 Oncogenic 59 circadian genes 59 APOE4 59 metabolizing enzyme 59 Bcr Abl 59 CAG repeats 59 piRNAs 59 cellular senescence 59 MEK1 59 radial glia 59 SIRT2 59 Histone deacetylase 59 erythrocytes 59 CCR1 59 Brodmann Area 59 virulence genes 59 CXCL5 59 fibril formation 59 cellular organelles 59 causative genes 59 enzyme aromatase 59 prion proteins 59 histone H3 59 glycoproteins 59 glutamic acid decarboxylase 59 primary cilia 59 TOP2A gene 59 glucocerebroside primarily 59 histone H4 59 E#F# 59 IFN γ 59 transcriptional regulation 59 cyclic AMP cAMP 59 TrkB 59 Purkinje cell 59 p# protein 59 lipid molecules 59 PrPSc 59 CCR3 59 neuroprotective effects 59 arachidonic acid AA 59 transmembrane receptor 59 coagulation cascade 59 epigenetic changes 59 selenoproteins 59 IKKß 59 CaMKII 59 neuropeptide Y 58 hyperplasia 58 3 carbinol 58 lymphangiogenesis 58 lipoprotein metabolism 58 receptor tyrosine kinase 58 glucosides 58 PAK1 58 regulates gene expression 58 hypermethylated 58 GAPDH 58 aMCI precursor 58 cardiac fibrosis 58 Nedd4 58 TXNIP 58 NPD1 58 collagen degradation 58 IL#R 58 COMT 58 glial cells 58 Homocysteine 58 inhibitory neurotransmitters 58 collagen VI 58 dystroglycan 58 Htt 58 ApoE gene 58 glycosaminoglycans 58 Vascular endothelial growth 58 dehydrogenases 58 SCN5A 58 VCAM 1 58 MEF2A 58 atherosclerotic lesions 58 NF kB 58 orally bioavailable mimics 58 Oxidative damage 58 PI3K/Akt pathway 58 PrP 58 calpain 58 CYP#C# [002] 58 cytochrome P 58 TNFR 58 prostaglandin E2 PGE2 58 tropomyosin 58 inhibit enzymes 58 basal forebrain 58 CYP#D# 58 cell nuclei 58 neurotransmitter GABA 58 transmembrane proteins 58 methyl D aspartate 58 progressive neurodegenerative disorder 58 GABAergic 58 amyloid pathology 58 LPA1 58 CFTR cystic fibrosis transmembrane 58 chromosomal regions 58 EAAT2 58 oxysterols 58 transgenic mice expressing 58 Akt pathway 58 serine threonine kinase 58 biochemical marker 58 neuritic 58 APOE gene 58 triacylglycerol 58 CIB1 58 oligodendrocytes 58 mGluR5 antagonist 58 immunoreactivity 58 NFkB 58 polyamine 58 CDH# 58 Lp PLA 2 58 VEGF vascular endothelial 58 polyglutamine 58 cholesterol metabolism 58 calcineurin 58 HIF 1α 58 Neuregulin 1 58 MDMX 58 urinary excretion 58 PPARg 58 TNFα 58 neuronal plasticity 58 selectively inhibits 58 neuropsychiatric diseases 58 #q#.# [002] 58 xenograft tumors 58 TGFβ 58 spermidine 58 mediated apoptosis 58 mitochondrial proteins 58 immunoregulatory 58 beta adrenergic receptors 58 glutathione GSH 58 neurodegenerative disorder 58 malondialdehyde 58 constitutively active 58 platelet activation 58 behavioral abnormalities 58 insoluble proteins 58 DNA methylation patterns 58 Osteoclasts 58 adhesion molecules 58 thromboxane A2 58 Rap1 58 Six3 58 glycated 58 vacuolar 58 p#Kip# 58 plasminogen activator inhibitor 58 LDLR 58 E3 ubiquitin ligase 58 JNK pathway 58 elastic fibers 58 homodimer 58 evolutionarily conserved 58 KLF2 58 lyase 58 sarcomatoid 58 CatB 58 cyclooxygenase 2 58 Th# cells 58 neurotrophic factor 58 IRAK1 58 pyrrolysine 58 inflammasome 58 susceptibility gene 58 epithelial tumors 58 cardiac hypertrophy 58 C1q 58 dermatophytes 58 PIP2 58 lipoprotein 58 Raf MEK ERK 58 downstream effector 58 medial temporal 58 miR# 58 fatty plaques 58 TAp# 58 HER1 58 lymphoid cells 58 muscular dystrophies 58 glutamate receptor 58 epigenetic markers 58 carboxyl terminal 58 cytochrome P# 58 microRNA expression 58 apolipoprotein E APOE 58 pro apoptotic 58 haematopoietic 58 HDAC enzymes 58 transcriptional repression 58 AMPA receptors 58 excess uric acid 58 autoantibodies 58 gastrin 58 KLF# 58 Lyn kinase 58 bone morphogenic protein 58 protein encoded 58 collagenous 58 mesothelial cells 58 cyclin D1 58 colocalization 58 antiproliferative effects 58 β1 58 glial cell