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(Click for frequent words.) 75 noradrenergic 73 glutamatergic 72 ERK1 2 71 serotonergic 71 modulatory 71 afferents 70 nociceptors 70 hyperalgesia 70 vagal 70 dose dependently 70 IL 1β 70 dopaminergic 69 LPS induced 69 hypothalamic pituitary adrenal axis 69 GABAergic 69 nitric oxide synthase NOS 69 acid GABA 69 IFN γ 69 mitogenic 69 mineralocorticoid 69 c Fos 69 N methyl 69 microglial 69 HPA axis 69 TNFalpha 69 IL 1ß 69 overactivation 69 baroreceptor 69 muscarinic receptors 69 cholinergic 69 endogenous opioid 69 NKG2D 68 striatal 68 hypothalamic 68 acetylcholine receptor 68 afferent 68 neuronal plasticity 68 GABAA receptors 68 vasoactive 68 somatostatin 68 ACh 68 potentiation 68 inhibitory neurotransmitters 68 vasodilatation 68 neuronal differentiation 68 receptor subtypes 68 hypothalamic pituitary 68 ouabain 68 excitatory 68 autophagic 68 extracellular signal 68 D aspartate 67 dorsal horn 67 raphe 67 upregulates 67 inflammatory cytokine 67 striatal dopamine 67 M1 muscarinic 67 baroreflex 67 catecholamine 67 efferent 67 aminobutyric acid 67 allopregnanolone 67 hyperexcitability 67 IL6 67 posterior cingulate 67 #ß 67 ERK pathway 67 nicotinic 67 PPARgamma 67 proinflammatory 67 neurite outgrowth 67 intracellular signaling 67 γ secretase 66 mitogen activated protein kinase 66 vasomotor 66 beta adrenergic receptors 66 glutamate receptors 66 cAMP signaling 66 proteoglycan 66 PKC inhibitors 66 5 HT1A 66 neurotrophic 66 neurotransmitters serotonin 66 dopaminergic neurons 66 astrocytic 66 noradrenaline 66 adrenoceptor 66 polyamine 66 proton pump 66 adrenocortical 66 proximal tubule 66 ERK phosphorylation 66 prostaglandin synthesis 66 methyl D aspartate 66 muscarinic receptor 66 TRPV1 receptors 66 CEACAM1 66 receptor activation 66 neuroinflammatory 66 extracellular dopamine 66 microglial activation 66 TrkB 66 prostaglandin E2 66 IL #p# 66 calcitonin gene related 66 antiapoptotic 66 neuronal signaling 66 IFN g 66 nigrostriatal 66 p#Kip# 66 vasodilatory 66 eNOS 66 mesolimbic 65 mediated inhibition 65 neurotrophic factors 65 neurofilament 65 tyrosine hydroxylase 65 mRNA expression 65 inducible nitric oxide synthase 65 mu opioid 65 BMP signaling 65 immunostimulatory 65 MAP kinase 65 epithelial cells lining 65 monoamine 65 histone acetylation 65 p# MAPK 65 miR #a [001] 65 IL 1beta 65 downregulates 65 ERK activation 65 isoenzyme 65 PC# cells 65 hypothalamic pituitary axis 65 TGF ß 65 lipopolysaccharide 65 Aâ 65 CGRP 65 osteoblast 65 ERalpha 65 excitotoxic 65 interleukin 1beta 65 mitochondrial respiration 65 adenylate cyclase 65 vasoconstriction 65 neuropeptide Y 65 vWF 65 alveolar epithelial cells 65 TRPV4 65 natriuretic 65 amyloid β 65 HIF 1alpha 65 neuronal dysfunction 65 elastase 65 cyclic AMP cAMP 65 p# activation 65 CTGF 65 trigeminal 65 dopamine reuptake 65 aberrantly activated 65 proinflammatory cytokines 65 adenosine diphosphate ADP 65 steroidogenic 65 serum cortisol 65 ERK signaling 65 hyperactivation 65 vasoconstrictor 65 prostaglandin E2 PGE2 65 downregulate 65 β1 65 serotonin synthesis 64 renin angiotensin aldosterone 64 chloride secretion 64 depolarizing 64 sensory neuron 64 5 hydroxytryptamine 64 cytoprotective 64 parietal cortices 64 Angiotensin II 64 NF kappaB activation 64 transgene expression 64 Th1 cells 64 neurohormonal 64 proapoptotic 64 potent inhibition 64 noradrenalin 64 fatty acid oxidation 64 tau phosphorylation 64 TGF beta1 64 NFkappaB 64 thyrotropin 64 interferon γ 64 VEGF receptor 64 TNF α 64 Androgen receptor 64 beta endorphin 64 fibrotic disease 64 NMDAR 64 serotonergic neurons 64 autocrine 64 autoregulation 64 Upregulation 64 renal fibrosis 64 GH secretion 64 Hcrt 64 nAChRs 64 beta adrenergic 64 anti inflammatory cytokines 64 EGFR signaling 64 HepG2 cells 64 triiodothyronine 64 demyelination 64 neuro transmitters 64 galanin 64 receptor gamma 64 inhibitory 64 factor HGF 64 neuropeptides 64 excitatory neurotransmitter glutamate 64 cyclooxygenase 2 64 hepatic glucose production 64 receptor subtype 64 Dysregulation 64 Inhibitory 64 GABAergic interneurons 64 peptide CGRP 64 Aldosterone 64 PDGF BB 64 radicular 64 #HT#A 64 PTHrP 64 cyclooxygenase COX 64 STAT1 64 MAP kinases 64 glutamate signaling 64 glucocorticoid 64 nAChR 64 amino acid glutamate 64 Clusterin 64 receptor mediated 64 mitogen 64 c myc 64 GABA neurotransmitter 63 plasmacytoid dendritic cells 63 receptor tyrosine kinase 63 inhibitory effects 63 adrenergic 63 synaptic transmission 63 endothelial nitric oxide synthase 63 vascular endothelial cells 63 upregulating 63 p# alpha [001] 63 P2X 63 HIF 1a 63 habenula 63 SOCS3 63 mGluR2 63 AT1R 63 TNFα 63 Dopaminergic 63 adrenocorticotropic hormone 63 serine threonine 63 potentiated 63 Nicotinamide 63 anterior temporal lobe 63 overactivity 63 erythropoiesis 63 GHRH 63 tryptase 63 selective antagonist 63 decarboxylase 63 pyrimidine 63 osteoclast formation 63 TrkA 63 lytic 63 cyclic nucleotide 63 heme oxygenase 1 63 Nav#.# 63 phosphatidylinositol 3 63 adrenal cortex 63 estrogen receptor alpha 63 catabolism 63 leukotriene 63 inflammatory mediators 63 TGF b 63 P#X# receptors 63 pharmacological inhibition 63 mu opioid receptors 63 Androgen 63 guanosine 63 isoenzymes 63 dysregulated 63 selective inhibition 63 AgRP 63 ß catenin 63 gamma aminobutyric acid GABA 63 hormone secretion 63 inhibitory interneurons 63 Kupffer cells 63 kinase pathway 63 prefrontal brain 63 monocytes macrophages 63 N acetyl 63 steroidogenesis 63 RIP1 63 prolyl 63 electroencephalographic 63 beta subunit 63 Inosine 63 downregulating 63 63 downregulation 63 opioid peptides 63 TIMP 1 63 selective modulator 63 corticospinal 63 mitochondrial enzymes 63 adrenocorticotropic hormone ACTH 63 neurohormones 63 endothelium dependent 63 heme oxygenase 63 gastrointestinal motility 63 Norepinephrine 63 locomotor activity 63 partial agonist 63 thalamic 63 serotonin receptor 63 proteolytic 63 dephosphorylation 63 incretin 63 PPARg 63 osteoblast differentiation 63 upregulation 63 Abeta protein 63 Ca2 + 63 nociception 63 neurotransmitter GABA 63 circadian clock genes 63 immunomodulatory effects 63 ENaC 63 cytokine signaling 63 agonism 63 TGF ß1 63 glucocorticoid receptors 63 periaqueductal gray 63 dorsolateral 63 androgen receptor AR 63 induced apoptosis 63 Vasopressin 63 NKT cell 63 thermosensitive 63 prostanoid 63 Sgk1 63 mPFC 63 neuromuscular junction 63 agonist induced 63 secretory 63 acetylcholinesterase AChE 63 osteogenic 63 TGF β 63 cell adhesion molecule 63 Notch1 63 monoamines 63 Prolactin 63 neurotransmitter glutamate 63 pDCs 63 transcriptional activity 63 cholecystokinin CCK 63 ischemia induced 63 cyclooxygenase 63 PLA2 63 hypothalamus pituitary 63 humoral 63 allergic inflammation 63 transferase 63 glucocorticoid receptor 63 PTH secretion 63 innervation 63 synaptogenesis 62 natriuresis 62 depolarization 62 GLUT4 62 NR2B subunit 62 thromboxane A2 62 enkephalins 62 cholesterol homeostasis 62 AhR 62 aggrecan 62 experimentally induced 62 protein kinase C 62 glutamyl 62 serotonin reuptake 62 immunoreactivity 62 radiosensitivity 62 leptin signaling 62 LTB4 62 GABA receptor 62 postsynaptic 62 neurosteroids 62 gut motility 62 P#X# receptor 62 fast skeletal troponin 62 intraventricular 62 P cadherin 62 iNOS 62 adipokines 62 5 HT2A 62 somatosensory cortex 62 motoneurons 62 corticotropin 62 degranulation 62 nitric oxide synthase 62 endoplasmic reticulum stress 62 PKC isoforms 62 nitrotyrosine 62 Nampt 62 PPARγ 62 FOXO 62 regulated kinase ERK 62 growth hormone secretion 62 PDGFR 62 TRPM8 62 adhesion molecule 62 Brain derived neurotrophic 62 serine proteases 62 presynaptic 62 ABCA1 62 protein tyrosine phosphatases 62 DNMT1 62 voltage gated 62 mitochondrial biogenesis 62 EGF receptor 62 intestinal epithelium 62 NFκB 62 5 HT2A receptor 62 transcriptional regulator 62 neuronal excitability 62 phosphoinositide 62 GLP 1R 62 anterior pituitary 62 PKC inhibitor 62 dorsal root ganglion 62 β2 62 contractility 62 enkephalin 62 lysosomal 62 middle temporal gyrus 62 MDR1 62 ectopic expression 62 leukocyte infiltration 62 rostral 62 MT1 MMP 62 gamma aminobutyric acid 62 TNFa 62 BMAL1 62 dimerization 62 Leukotrienes 62 analgesic effects 62 PDGFR alpha 62 redox active 62 pro angiogenic 62 Adrenergic 62 airway hyper responsiveness 62 FKBP# 62 p tau 62 oculomotor 62 5 HT1A receptor 62 CCR2 62 μ opioid receptor 62 sensorimotor 62 E#F# 62 Purkinje cell 62 NADPH 62 synovial cells 62 hepatocellular 62 cyclic adenosine monophosphate cAMP 62 VE cadherin 62 alpha subunit 62 dysregulation 62 glucagon receptor 62 Neuropeptide Y 62 nutlin 3a 62 acetylcholine receptors 62 CagA 62 HMG CoA reductase 62 hydrolases 62 potent inhibitors 62 interleukin IL -6 62 neurosteroid 62 ligand induced 62 c fos 62 leukocyte recruitment 62 dopamine norepinephrine 62 anti apoptotic 62 downstream effector 62 matrix metalloproteinases 62 paracrine 62 cortical activation 62 peripheral tissues 62 interleukin IL -# 62 GluR1 62 LRP5 62 brain neurotransmitter 62 malonyl CoA 62 vimentin 62 insular cortex 62 neurotransmission 62 neuronal activity 62 FGFs 62 Rab5 62 dorsal root ganglia 62 inflammatory cytokines 62 AMPA receptor 62 Akt activation 62 pDC 62 WNK1 62 TGF alpha 62 GRK2 62 NFkB 62 opioid receptor antagonist 62 pRb 62 interleukin 1β 62 oxidative metabolism 62 rCBF 62 arcuate nucleus 62 adenosine receptors 62 P2Y 62 tyrosine phosphorylation 62 gyri 62 constitutively active 62 SSc 62 P selectin 62 platelet activation 62 glial 62 JAK2 enzyme 62 myoclonus 62 drug metabolizing enzymes 62 peroxidase 62 isoproterenol 62 induces apoptosis 62 P glycoprotein 61 gastrin 61 serum BDNF 61 glucose homeostasis 61 signaling cascades 61 mucosal immune 61 oxidases 61 cardiac autonomic 61 Amino acid 61 chemoattractant 61 S nitrosylation 61 mineralocorticoid receptor 61 osteoblastic 61 ChR2 61 NMDA N 61 TLR2 61 COL#A# 61 RAS RAF MEK 61 bile acid 61 urocortin 61 extracellular calcium 61 eicosanoid 61 coronary vasodilation 61 baroreceptors 61 muscarinic 61 downregulated 61 #β estradiol 61 IRE1 61 transcriptional activation 61 myogenic 61 TNF IL 61 XL# inhibits 61 TNFR 61 pituitary hormones 61 nerve conduction velocity 61 PI3K Akt 61 fronto 61 cotransporter 61 bradykinin 61 proinflammatory cytokine 61 interleukins 61 NAc 61 inferior frontal 61 proteolysis 61 osteolytic 61 CYP #A# 61 TGFβ 61 immunoreactive 61 mGluR 61 NR2B 61 GABAergic neurons 61 intracoronary 61 primidone 61 aldosterone 61 paxillin 61 HDAC2 61 osteoclastic 61 IKK2 61 exocytosis 61 mucociliary clearance 61 tumorigenicity 61 vagal nerve 61 5 HT6 receptor 61 CB1 receptor 61 axonal damage 61 #S proteasome 61 pleiotropic 61 calcium homeostasis 61 ziconotide 61 serotonin neurons 61 XP# Transported Prodrug 61 endotoxemia 61 neurotransmitter receptors 61 MEK1 61 electrophysiological 61 prostaglandin E1 61 K + ATPase 61 sensory nerve 61 epididymal 61 mediated apoptosis 61 SGPT 61 melatonin receptors 61 basolateral 61 endocannabinoid signaling 61 lipid homeostasis 61 colonic motility 61 1alpha 61 phospho 61 tolerogenic 61 species ROS 61 lymphotoxin 61 UCP1 61 somatosensory 61 microsomal 61 thermal hyperalgesia 61 vascular endothelial 61 V#F mutation 61 fibrogenesis 61 phosphoprotein 61 leukocyte adhesion 61 cardiac troponin 61 UCP2 61 ATPase 61 neuronal synapses 61 p# mitogen activated 61 pro apoptotic 61 globus pallidus 61 amylin 61 hypoperfusion 61 metabolizing enzyme 61 mesothelin 61 dopamine transporter 61 neurogenic 61 neuroendocrine 61 adipogenic 61 Akt phosphorylation 61 Abeta# 61 innate immune responses 61 cytoskeletal 61 cathepsin B 61 reductase 61 Hypothalamic 61 Kv#.# 61 adrenergic receptors 61 anti inflammatory cytokine 61 Xenopus oocytes 61 T#M 61 NF κB 61 apoptotic pathway 61 glycosyltransferase 61 NF kB pathway 61 H#K#me# 61 antiinflammatory 61 receptor blockers 61 glucocorticoid induced 61 cytochrome c oxidase 61 Oncogenic 61 cytosolic 61 monocyte 61 ERBB2 61 aberrant activation 61 Th1 type 61 corticotropin releasing hormone 61 experimental allergic encephalomyelitis 61 agonists antagonists 61 Phosphorylation 61 induced neuronal 61 5 HT2A serotonin 61 caveolin 1 61 Th2 immune 61 neprilysin 61 cyclic AMP 61 lipogenesis 61 hCG beta 61 D aspartic acid 61 oxidase 61 GAPDH 61 junctional 61 kainate 61 Parkinsonian 61 NMDA antagonist 61 Hedgehog signaling 61 neointimal hyperplasia 61 POMC neurons 61 neuropeptide 61 subthalamic nucleus STN 61 serotonin norepinephrine 61 intracellular signal transduction 61 basophils 61 myocardial tissue 61 hypothalamic pituitary adrenal HPA 61 VEGF expression 61 acyl CoA 61 mechanical allodynia 61 antiangiogenic 61 neuronal degeneration 61 potently inhibited 61 lymphocyte activation 61 SIRT2 61 sensory neurons 61 Cathepsin B 61 Monocyte 61 olfactory receptor neurons 61 mTOR signaling pathway 61 anterior temporal 61 S#A# [002] 61 motor neuron degeneration 61 plasminogen 61 innervated 61 MyoD 61 Fas ligand 61 plasma pharmacokinetics 61 gamma amino butyric 61 inhibitory transmitter 61 p#NTR 61 mucosal inflammation 61 TLR4 61 β catenin 61 gastric mucosa 61 deacetylation 61 protein tyrosine phosphatase 1B 61 fibrin deposition 61 Glucocorticoid 61 hepatic enzyme 61 IGF1R 61 Oxidative 61 homeostatic 61 parkinsonian 61 Acetylcholine 61 humoral immunity 61 Akt signaling 61 ^ sup #m 61 intracellular calcium 61 GABAB receptors 61 IFN β 60 CaMKII 60 plasmid encoding 60 potentiates 60 alveolar macrophages 60 neurotransmitter receptor 60 Kir#.# 60 opioid receptor 60 FGFR4 60 serotonin transporter 60 experimental autoimmune encephalomyelitis 60 myofibroblast 60 fibrotic 60 CXCL# 60 thromboxane 60 denervation 60 carcinoembryonic antigen 60 mTOR signaling 60 glutamate transporters 60 serum antibodies 60 hypometabolism 60 PHD2 60 caveolin 60 ERa 60 N cadherin 60 calcineurin 60 CCL# 60 mPGES 1 60 gliosis 60 VEGFR1 60 glomerular 60 COX2 60 HuR 60 inducible 60 Smad3 60 pro inflammatory cytokines 60 c Src 60 subtype selective 60 #β HSD1 60 serum TSH 60 bone morphogenetic proteins 60 monocyte chemotactic protein 60 medial prefrontal 60 antidepressant efficacy 60 transduced 60 PKC delta 60 palytoxin 60 endocannabinoid system 60 hormone secreted 60 cytokine interleukin 60 occipital cortex 60 myofibroblasts 60 pharmacologic approaches 60 CB2 receptor 60 act synergistically 60 CYP #D# 60 dopamine signaling 60 opioid induced 60 Th2 60 cortico 60 posttranslational modification 60 intestinal mucosal 60 adenosine receptor 60 5alpha reductase 60 CaM 60 phosphorylates 60 eIF4E 60 Protein Kinase C 60 PDE#A 60 PGC 1α 60 PTPN# 60 constitutively expressed 60 colon carcinogenesis 60 potent stimulator 60 atherogenesis 60 selectively inhibits 60 epithelia 60 cytochrome P 60 endogenous cannabinoids 60 excitatory neurotransmitter 60 gene polymorphisms 60 airway reactivity 60 lipopolysaccharide LPS 60 sensory nerves 60 FasL 60 NMDA receptors 60 mu opioid receptor 60 TTR gene 60 STAT3 signaling 60 COX enzymes 60 uroguanylin 60 nNOS 60 palmitate 60 acinar 60 ATP hydrolysis 60 activin 60 peroxynitrite 60 myo inositol 60 oligomerization 60 eotaxin 60 triiodothyronine T3 60 antiproliferative effects 60 PPAR γ 60 apolipoproteins 60 regulated kinase 60 Th2 cytokines 60 inverse agonist 60 chemokine receptor 60 airway hyperresponsiveness 60 cytidine 60 underlying vasculopathy 60 costimulatory 60 chemotactic 60 pituitary hormone 60 mutant huntingtin protein 60 IgG4 60 gastric acid secretion 60 neuronal apoptosis 60 selective agonists 60 osteoclast 60 Î ² 60 isotypes 60 dorsal anterior cingulate cortex 60 pyramidal cells 60 potent inducer 60 synaptic function 60 NQO1 60 striated muscle 60 serine threonine kinase 60 lesional 60 NKX#.# 60 RANK Ligand 60 Flt3 60 Glucocorticoids 60 5HT 60 mTORC1 60 neuroinflammation 60 intermittent hypoxia 60 vesicle trafficking 60 HIF 1α 60 renal tubular 60 tenascin C 60 thrombin receptor 60 LPA1 receptor 60 remyelination 60 pentoxifylline 60 synaptic plasticity 60 uPAR 60 collagen deposition 60 selectively binds 60 TGF beta signaling 60 motilin 60 neuronal 60 gene encodes 60 cell adhesion molecules 60 antiproliferative activity 60 membrane permeability 60 corticotrophin releasing factor 60 myeloperoxidase 60 intestinal mucosa 60 peptide YY PYY 60 lysyl oxidase 60 ErbB receptors 60 hydroxylase 60 PECAM 1 60 focal adhesions 60 1beta 60 thyroid hormone receptor 60 aminopeptidase 60 vomeronasal 60 rostral anterior cingulate cortex 60 oncogenic transformation 60 c MET 60 corticotropin releasing factor 60 beta actin 60 trophoblast cells 60 Overexpression 60 neuronal nitric oxide synthase 60 TGF β1 60 AMACR 60 TRPV1 60 Peroxisome proliferator activated 60 torsade de pointes 60 dystroglycan 60 cellular prion protein 60 MAPK pathway 60 hypoxia induced 60 pathophysiological effects 60 inotropic 60 type glutamate receptor 60 Runx2 60 lactate dehydrogenase 60 lymphangiogenesis 60 cytokines IL 60 somatostatin receptor 60 adipocyte 60 norepinephrine 60 anterograde 60 subgenual cingulate 60 soluble TNF receptor 60 GI motility 60 anterior cingulate 60 GLI1 60 MAPK 60 prostaglandin E 60 factor BDNF 60 gut mucosa 60 mu opioid receptor antagonist 60 TNF receptors 60 apoptosis pathway 60 neuro transmitter 60 HEK# cells 60 Angiotensin 60 Wnt beta catenin 60 collagen degradation 60 virulence genes 60 TRPA1 60 activated protein kinase 60 effector memory 60 glucose transporter 60 IFN gamma 60 neural pathway 60 adrenal medulla 60 selectively inhibited 60 HER2 overexpression 60 cyclic guanosine monophosphate cGMP 60 RRM1 60 sortilin 60 neuroleptic 60 phosphorylase 60 bronchial epithelial cells 60 gamma oscillations 60 covalently bound 60 PEDF 60 TRPV3 60 contractile 60 selective agonist 60 VMAT2 60 E cadherin expression 60 melatonin receptor 60 gonadotropin releasing hormone GnRH 60 ciliary 60 excitatory synapses 60 CD#b