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(Click for frequent words.) 76 upregulated 72 overexpression 69 mRNA expression 69 methylated 69 phosphorylated 69 downregulated 68 proto oncogene 67 ERBB2 67 constitutively expressed 67 hypermethylation 67 cyclin D1 67 transfected 66 overexpressing 66 mitogen activated protein kinase 66 STAT3 66 WT1 66 mice lacking 65 protein encoded 65 CXCL# 65 Akt 65 homodimers 65 Overexpression 65 DNMT1 65 EGFR 65 mRNA 65 genes encoding 65 induces apoptosis 65 c MYC 65 tumor suppressor gene 64 transcription factors 64 overexpress 64 tyrosine kinase 64 transcription factor 64 RASSF1A 64 E cadherin 64 EZH2 64 MAPK 64 FasL 64 isoforms 64 ERK1 2 64 TNFalpha 64 miR #b [001] 64 promoter methylation 64 catenin 64 MDM2 63 caveolin 1 63 phosphorylate 63 upregulation 63 IL 1beta 63 Foxp3 63 phosphorylates 63 hTERT 63 miR #b [002] 63 LRP6 63 hypoxia inducible factor 63 iNOS 63 uPAR 63 EGFRvIII 63 oncogenes 63 tyrosine kinases 63 Smad3 63 IGFBP 63 Akt1 63 Notch1 63 JAK2 63 constitutively 63 STAT1 63 oncoprotein 63 immunoreactivity 63 regulated kinase ERK 63 oncogenic 62 androgen receptor AR 62 HER3 62 GLI1 62 S#A# [002] 62 transactivation 62 beta catenin 62 CD#b 62 melanocyte 62 pRb 62 miRNAs 62 BCR ABL 62 constitutively active 62 CagA 62 ADAM# 62 potent inhibitor 62 PDGFR 62 ß catenin 62 protein kinases 62 Pten 62 cell adhesion molecule 62 vimentin 62 MAP kinase 62 induce apoptosis 62 MUC1 62 thioredoxin 62 oncoproteins 62 CD# [002] 62 Skp2 62 activating mutations 62 c myc 62 Stat3 62 factor receptor 62 receptor tyrosine kinase 62 MAPK pathway 62 evolutionarily conserved 62 PAK1 62 receptor CXCR4 61 Treg cells 61 estrogen receptor 61 GNAQ 61 miRNA genes 61 constitutively activated 61 NKX#.# 61 NKG2D 61 glycosylated 61 TAp# 61 deacetylation 61 IFN gamma 61 downregulation 61 Th1 61 phosphorylation 61 bcl 2 61 surface glycoprotein 61 phosphatases 61 myocyte enhancer factor 61 plasmacytoid dendritic cells 61 induced apoptosis 61 IL 1β 61 VEGFR2 61 gene encoding 61 caveolin 61 wildtype 61 glioblastoma cells 61 GRP# 61 vascular endothelial cells 61 eosinophils 61 HBx 61 HIF 1alpha 61 c MET 61 oncogene 61 mRNAs 61 matrix metalloproteinase 61 telomerase reverse transcriptase 61 transcriptional repressor 61 4E BP1 61 c Myc 61 ERa 61 HER2 neu 61 mesothelin 61 Her-2/neu 61 GSTT1 61 clusterin 61 HOTAIR 61 lymphoid cells 61 MTHFR 61 microRNA miR 61 overexpressing cells 61 RhoA 61 ER alpha 61 IGF 1R 61 Sp1 61 dysregulated 61 activin 61 histone 61 isoform 61 GSTP1 61 mutant p# 61 HER2 receptor 60 lymphoid 60 stromal cells 60 adenocarcinomas 60 ErbB4 60 neuroblastoma cells 60 TIMP 60 dephosphorylation 60 myeloid cells 60 pDCs 60 RUNX3 60 alternatively spliced 60 missense mutations 60 EphB4 60 tyrosine kinase receptor 60 thrombospondin 60 ERK signaling 60 cyclic AMP cAMP 60 survivin 60 regulated kinase 60 tumor suppressor 60 heterodimers 60 Activating mutations 60 transmembrane protein 60 Mcl 1 60 MMP9 60 PI3K Akt 60 lymphoid tissue 60 decarboxylase 60 kinases 60 EpCAM 60 ubiquitinated 60 sFlt 1 60 valine 60 extracellular signal 60 deficient mice 60 IL #R 60 aberrantly activated 60 Raf MEK ERK 60 cofilin 60 CHD5 60 COL#A# 60 virulence genes 60 CCR9 60 ErbB2 60 epithelial tumors 60 Clusterin 60 eNOS 60 transgene expression 60 Cyclin E 60 leptin receptor 60 GRK2 60 Oct4 60 HER2/neu 60 tumorigenesis 60 encodes protein 60 apoE 60 GATA3 60 GTPase 60 β catenin 60 enzymatic activity 60 PGE2 60 Kupffer cells 60 CDKN2A 60 Src 60 PTEN gene 60 MLH1 60 ganglioside 60 VEGFR1 60 Notch signaling 60 cathepsin B 60 HDACs 60 TMEM#B 60 serine threonine 60 miR #a [002] 60 transduced 60 Hedgehog signaling 60 E#F# 60 CCR2 60 hypermethylated 60 paxillin 60 Hedgehog pathway 60 EGFR protein 60 phosphatidylinositol 60 Rab5 60 PTHrP 60 aromatase 60 hydroxylase 60 SPINK1 60 inhibited tumor 60 ectopic expression 60 EGFr 60 PTP1B 60 IL #p# 60 tumor suppressor protein 60 tumor suppressor genes 59 FOXO3a 59 cell adhesion molecules 59 HIF 1α 59 adenylate cyclase 59 EphA2 59 ncRNAs 59 Phosphorylation 59 p# protein 59 estrogen receptor alpha 59 KIT mutations 59 Stat5 59 PI3 kinase 59 ErbB 59 claudin 59 proteases 59 potent inhibitors 59 LDLR 59 IGF IR 59 FOXP3 59 serine threonine kinase 59 miR# 59 chemokine 59 cyclin dependent kinase 59 adhesion molecule 59 coactivator 59 acetylation 59 p#NTR 59 Macrophage 59 GBM tumors 59 FLT3 59 TGF β 59 FAK 59 PTPN# 59 cells transfected 59 cAMP 59 HER2 receptors 59 tyrosine phosphorylation 59 NFκB 59 NOTCH1 59 intestinal epithelial cells 59 Bcl XL 59 chemokine receptors 59 VCAM 1 59 kinase gene 59 regulates gene expression 59 upregulates 59 estrogen receptor beta 59 Aβ 59 V#F mutation 59 serotonin receptor 59 HIF 1a 59 MSH2 59 CD8 + 59 pro inflammatory cytokine 59 hepatocellular carcinomas 59 PIK3CA 59 CD# molecule 59 lysosomal 59 estrogen receptors 59 HSCs 59 P selectin 59 mutational status 59 Th2 59 cytosolic 59 C. albicans 59 VEGF receptor 59 acetylated 59 KRAS oncogene 59 Abeta# 59 cytoplasmic 59 myeloid derived 59 FGFR2 59 GSTM1 59 secreted protein 59 CXCR4 59 Cdc# 59 cisplatin resistant 59 autoantibodies 59 NFkB 59 cyclin dependent kinase inhibitor 59 leukemic cells 59 laminin 59 IGFBP2 59 Nedd4 59 bronchial epithelial cells 59 phosphatase 59 methylation 59 Wnt signaling 59 PP2A 59 serine protease 59 MEK1 59 amino terminal 59 p# [001] 59 Rap1 59 FUS1 59 TERT 59 SOD1 59 β 59 potent inhibition 59 HDAC2 59 Bcl xL 58 NFAT 58 LDL receptor 58 H#K# [002] 58 carcinoembryonic antigen 58 activating mutation 58 NF kB 58 POMC neurons 58 TSC1 58 Immunohistochemical analysis 58 transgenic mice 58 kinase 58 RANTES 58 MMP2 58 H#K#me# 58 FGFR3 58 MnSOD 58 IL 1ß 58 CCR7 58 TNFa 58 TGF ß1 58 retinoic acid receptor 58 FGFR4 58 IGF1R 58 inhibitory effects 58 ERK 58 CXCL5 58 Wnt signaling pathway 58 myocardin 58 CD# antigen 58 Mice lacking 58 unmethylated 58 TGF ß 58 B7 H3 58 VEGFR 58 Ki# 58 Upregulation 58 androgen receptor 58 potently inhibited 58 miRNA expression 58 c Myb 58 KLF# 58 TNF α 58 tumor suppressors 58 PON1 58 ribosomal protein 58 factor HGF 58 p#Kip# 58 TGF alpha 58 SATB1 58 Flt3 58 cytokeratin 58 caspase 58 autocrine 58 signaling pathway 58 lymph node metastasis 58 EGFR expression 58 microRNAs 58 Eg5 58 CatB 58 myeloid 58 RAS RAF MEK 58 cytokines IL 58 phospho 58 xenograft tumors 58 p# p# 58 inflammatory cytokines 58 hepatoma 58 coding genes 58 inducible nitric oxide synthase 58 protein kinase 58 receptor protein 58 breast carcinomas 58 HepG2 cells 58 Th# cells 58 proapoptotic 58 microglial cells 58 TOP2A 58 autophagic 58 cysteine residues 58 SOX9 58 acetyl CoA 58 pro apoptotic 58 binds selectively 58 c KIT 58 phosphatidylinositol 3 58 1alpha 58 repressor 58 TGFb 58 TSP1 58 presenilin 58 transfected cells 58 glutathione S transferase 58 B7 H1 58 protein kinase C 58 AT1R 58 isoenzyme 58 epithelial 58 Jhdm2a 58 histone deacetylases 58 downregulate 58 NF κB 58 underexpressed 58 monocyte chemoattractant protein 58 KLF4 58 OCT4 58 phosphoprotein 58 BCL2 58 RRM1 58 TGF beta 58 glycosylation 58 SNP rs# [001] 58 carboxyl terminal 58 casein kinase 58 splice variants 58 RANKL 58 nestin 58 homodimer 58 transiently transfected 58 oncogenic transformation 58 3'UTR 58 glycolipids 58 transcriptional activation 58 Cx# [001] 58 p# mutations 58 tropomyosin 58 rs# [004] 58 p# deficient 58 TIMP 1 58 SGK1 57 GM CSF 57 beta subunit 57 monocyte chemotactic protein 57 pyruvate kinase 57 IFN γ 57 xenograft models 57 cultured cells 57 heterozygous 57 Her2/neu 57 TORC1 57 gene polymorphisms 57 HER2 protein 57 signal transduction pathways 57 1α 57 CEACAM1 57 AMACR 57 epithelial cancers 57 IGFBP 3 57 peripheral blood mononuclear 57 TGF β1 57 adrenal cortex 57 HGF 57 NKT cells 57 nAChR 57 CDK4 57 somatostatin 57 BRAF mutations 57 antiproliferative activity 57 hCG Beta 57 cyclic AMP 57 PI3K 57 extracellular domain 57 EGF receptor 57 Tie2 57 apoptotic pathway 57 poly ADP ribose polymerase 57 differentially expressed 57 Myc 57 miR #a [001] 57 gene encodes 57 Aurora kinase 57 imprinted genes 57 superfamily 57 interferon IFN 57 EGFR mutations 57 dehydrogenase 57 heterozygotes 57 NKX2 57 5 lipoxygenase 57 cytoplasmic domain 57 lacZ 57 KRAS mutations 57 breast epithelial cells 57 CD# CD# 57 phosphate S1P 57 homozygotes 57 procaspase 3 57 FANCD2 57 intron 57 nitric oxide synthase 57 receptor molecule 57 p#INK#a 57 TLR4 57 VEGF receptors 57 cytokine signaling 57 GSK 3ß 57 proinflammatory cytokines 57 RKIP 57 transgenic mice expressing 57 PI3K pathway 57 costimulatory 57 LKB1 57 erythrocytes 57 proteins encoded 57 cardiac fibroblasts 57 ALDH 57 resistin 57 anti inflammatory cytokine 57 alkaline phosphatase 57 insulin receptors 57 Wnt 57 transmembrane domains 57 PKM2 57 palladin 57 Immunohistochemical staining 57 PAR1 57 murine 57 somatic mutations 57 noncoding 57 metalloproteinase 57 VEGF expression 57 miR 57 MYCN 57 glyceraldehyde 3 57 gp# [002] 57 nucleolin 57 glycoproteins 57 mutant proteins 57 neoplastic 57 null mice 57 polyamine 57 TCF#L# 57 DLX5 57 SIRT2 57 osteopontin 57 presynaptic 57 transcriptional regulation 57 eotaxin 57 HMG CoA reductase 57 cytokine 57 cystic fibrosis transmembrane conductance 57 angiopoietin 57 glioma cells 57 DISC1 57 CCN2 57 1ß 57 interleukin 57 PC3 cells 57 messenger RNA mRNA 57 JAK2 enzyme 57 receptor 57 EGFR gene 57 K ras mutations 57 synthase 57 demethylase 57 colorectal carcinoma 57 lipoxygenase 57 MAPKs 57 rs# [001] 57 Rac1 57 MT1 MMP 57 FGFR1 57 activated lymphocytes 57 Ang2 57 forkhead 57 Syk 57 keratinocytes 57 transcriptional regulator 57 PTEN 57 BMP2 57 microRNA expression 57 Hh pathway 57 integrins 57 neurofibromin 57 pro angiogenic 57 TGFß 57 Cathepsin B 57 skin fibroblasts 57 Id1 57 protein tyrosine kinases 57 microRNA molecules 57 NF kB pathway 57 receptor subtype 57 nM 57 cytokine IL 57 MeCP2 57 SIRT1 57 Pin1 57 utrophin 57 fusion protein 57 selectively binds 57 mTOR signaling 57 BRAF V#E 57 dimers 57 astrocytes 57 heparanase 57 gene amplification 57 VE cadherin 57 Smad7 57 osteocalcin 57 midgut 57 estrogen receptor progesterone receptor 57 tumorigenic 57 ABCA1 57 protein tyrosine kinase 57 sequence homology 57 JAK STAT 57 ubiquitin ligase 57 kinase enzymes 57 Hypoxia Inducible Factor 57 cyclin E 57 CXCR2 57 p# mitogen activated 57 ERK pathway 57 leukemic cell 57 receptor gene 57 lymphocytes 56 PAX5 56 interleukins 56 intercellular adhesion molecule 56 fibronectin 56 ERalpha 56 homologues 56 MDR1 56 HER-2/neu 56 untranslated regions 56 CYP#B# 56 cytochrome c 56 E3 ligase 56 BRAF mutation 56 aldehyde dehydrogenase 56 anaphase promoting complex 56 mRNA transcripts 56 Factor Receptor 56 rs# [002] 56 IRE1 56 subcellular localization 56 coexpression 56 VHL gene 56 CD1d 56 IKKß 56 downregulates 56 myo inositol 56 micro RNAs 56 GPNMB 56 metastasis 56 adrenergic receptors 56 PKD1 56 MiRNAs 56 focal adhesion kinase FAK 56 intronic 56 P cadherin 56 carcinomas 56 S1P 56 epithelial cells 56 matriptase 56 Lrp5 56 rRNA 56 peroxidase 56 gene polymorphism 56 K + ATPase 56 receptor gamma 56 PPARg 56 membrane protein 56 GPC3 56 chemokine receptor 56 cytokines 56 TACI 56 telomerase activity 56 CDKs 56 Protein Kinase C 56 Runx2 56 beta amyloid peptide 56 ubiquitination 56 UCP2 56 DLC1 56 Methylation 56 gene expression patterns 56 N Myc 56 p# MAPK 56 major histocompatibility complex 56 Fas ligand 56 stroma 56 cyclins 56 papillary 56 chemokines 56 estrogen receptor ER 56 Polycomb 56 chemoattractant 56 Cyclin D1 56 megakaryocytes 56 Nrf2 56 HLA DR 56 polyadenylation 56 SOCS3 56 dimerization 56 E selectin 56 CD4 + CD# 56 immunoreactive 56 pseudogenes 56 epithelial cells lining 56 receptors EGFR 56 signaling molecule 56 PDE#A 56 matrix metalloproteinases MMPs 56 tumor antigen 56 bile acid 56 endostatin 56 mitochondrial enzyme 56 56 inhibitory receptor 56 RAD# [001] 56 RNA polymerase II 56 miRNA 56 MDA MB 56 Caspase 56 transmembrane receptor 56 leptin receptors 56 FOXO 56 ligand TRAIL 56 epithelial cell 56 c Fos 56 huntingtin 56 eukaryotic 56 TGF b 56 Supplementary Fig 56 BRAF protein 56 lymphoblasts 56 effector cells 56 HbF 56 mTOR 56 phosphoinositide 56 H#K# methylation 56 TET2 56 XBP1 56 IgG1 56 Dysregulation 56 signaling pathways 56 eIF4E 56 LNCaP cells 56 Th2 cells 56 proline 56 atypical hyperplasia 56 p# activation 56 pro inflammatory cytokines 56 TGF beta1 56 IFNg 56 isotype 56 Mutational 56 tryptase 56 GAPDH 56 SIRT6 56 p# mutation 56 isoleucine 56 GlcNAc 56 cell signaling pathways 56 matrix metalloproteinases 56 Rho GTPase 56 beta actin 56 osteoblast 56 sortilin 56 chromosomal rearrangement 56 Î ² 56 serotonin receptors 56 tensin homolog 56 receptor kinase 56 SETDB1 56 IL6 56 Nkx#.# 56 granule cells 56 ribosomal proteins 56 Janus kinase 56 NF kappaB 56 genomic instability 56 methyltransferase 56 Wnt pathway 56 ERK1 56 adenomatous polyposis coli 56 transcriptionally 56 TTR gene 56 autoantibody 56 PKCi 56 MyoD 56 ubiquitylation 56 HIF 2alpha 56 transmembrane 56 Rb#/p# 56 hepatocyte growth 56 metalloprotease 56 integrin 56 FGF2 56 Caveolin 1 56 CYP# [002] 56 factor EGF 56 cell motility 56 cyclin dependent kinases CDKs 56 synthetase 56 CLL cells 56 TORC2 56 mTOR pathway 56 premalignant 56 Mice deficient 56 BCL6 56 Alu elements 56 alveolar epithelial cells 56 prolyl 56 histone deacetylation 56 ApoB 56 inverse agonist 56 PrP 56 BACE1 56 CaMKII 56 cathepsins 56 miRs 56 FGF# 56 ErbB3 56 NFKB 56 protein phosphatase 56 homozygous 56 inhibits tumor 56 tumor cells 56 mutant protein 56 glycoprotein 56 Aß 56 PKC delta 56 acyl CoA 55 cadherin 55 polypeptide 55 colorectal tumors 55 Bcl 2 55 Klf4 55 TLR2 55 ERb 55 BMAL1 55 HDAC 55 histone H3 55 ATPase 55 syngeneic 55 N acetyltransferase 55 P. gingivalis 55 protein p# 55 suppressor cells 55 monocyte 55 Interferon gamma 55 B Raf 55 VSV G 55 histone H4 55 deacetylase 55 mesenchymal cells 55 excitatory synapses 55 microglial activation 55 Hsp# [001] 55 apoptotic 55 CD#c 55 pDC 55 basolateral 55 histone modifications 55 overactivated 55 lung carcinomas 55 triacylglycerol 55 TNFR1 55 encode proteins 55 Wnt#b 55 CD# + [001] 55 astrocytic 55 p# gene 55 epithelia 55 hypomethylation 55 situ LCIS 55 lactate dehydrogenase 55 CTLA 4 55 B lymphocytes 55 PC# cells 55 substrate specificity 55 neurite outgrowth 55 elastase 55 RNAs 55 rs# [003] 55 occludin 55 endocytosis 55 radial glia 55 ERK2 55 Nampt 55 LRP5 55 alpha synuclein 55 brain derived neurotrophic 55 mRNA encoding 55 gene expression 55 TXNIP 55 gamma secretase 55 factor receptor EGFR 55 single nucleotide polymorphism 55 thrombin receptor 55 heme oxygenase 55 transmembrane proteins 55 PTEN mutations 55 FGF receptor 55 histologically 55 orthologs 55 TNF alpha IL 55 #q# [001] 55 TNFα 55 tau protein 55 exon 55 Arf gene 55 IRAK1 55 MEF2 55 synuclein 55 Wwox 55 TRAIL induced apoptosis 55 apical membrane 55 calcineurin 55 5 HT1A 55 transcriptional repression 55 cell acute lymphoblastic 55 progesterone receptor negative 55 CCL2 55 kDa protein 55 CTGF 55 effector memory 55 homologs 55 hematopoietic cells 55 non coding RNAs 55 Lyn kinase 55 Vpu 55 c Src 55 μg ml 55 ERCC1 55 neuroblastomas 55 NF kB activation 55 androgen receptors 55 colon carcinoma 55 E3 ubiquitin ligase 55 S#K# 55 maternally inherited