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(Click for frequent words.) 75 ERK1 2 74 catenin 74 serine threonine 73 mRNA expression 72 phosphoprotein 72 cell adhesion molecule 72 cytoplasmic domain 72 HepG2 cells 72 mitogen activated protein kinase 71 TGF beta1 71 ectopic expression 71 serine threonine kinase 71 ERalpha 71 reductase 71 homolog 71 serine protease 70 transmembrane protein 70 Overexpression 70 hydroxylase 70 1beta 70 VEGF receptor 70 cytochrome 70 constitutively active 70 lipoxygenase 70 induced apoptosis 70 MAP kinase 70 phosphatidylinositol 3 70 transcriptional repressor 70 cells transfected 70 peroxidase 70 NKG2D 70 p# MAPK 70 cytokeratin 70 receptor tyrosine kinase 70 ß catenin 70 androgen receptor AR 69 69 carcinoembryonic antigen 69 tyrosine kinase receptor 69 Phosphorylation 69 dimerization 69 ribosomal protein 69 At#g# 69 extracellular domain 69 β catenin 69 STAT1 69 methyltransferase 69 cathepsin B 69 HIF 1alpha 69 Upregulation 69 downregulates 69 N acetyl 69 TNF α 69 regulated kinase 69 TNFalpha 69 FGFR3 69 dehydrogenase 69 bile acid 69 Rab5 69 prolyl 69 proto oncogene 69 SIRT2 69 isoenzyme 69 caveolin 69 Catenin 69 pyrimidine 69 MEK1 69 thrombospondin 69 antiapoptotic 69 vimentin 69 Oncogenic 69 phosphorylated 68 cyclin dependent kinase inhibitor 68 RhoA 68 triphosphate 68 EGFP 68 ERK signaling 68 p#Kip# 68 phosphorylates 68 adrenergic receptors 68 FasL 68 uPAR 68 endonuclease 68 NF κB 68 protein tyrosine phosphatase 68 IL 1beta 68 secretase 68 prostaglandin E2 PGE2 68 4E BP1 68 histone H3 68 homodimers 68 E#F# 68 thymidine 68 matrix metalloproteinase 68 beta subunit 68 TGF ß 68 p# mitogen activated 68 cyclooxygenase COX 68 RANTES 68 Interferon gamma 68 transactivation 68 enolase 68 adenylate cyclase 68 Cytoplasmic 68 transferase 68 CD#b 68 microglial 68 LDL receptor 68 supernatants 68 isoform 68 matrix metalloproteinases 68 Rap1 68 alpha subunit 68 PAK1 68 constitutively expressed 68 LPS induced 68 pDC 68 phosphatase 67 proximal tubule 67 esterase 67 transduced 67 amino terminal 67 operon 67 homodimer 67 ERBB2 67 F actin 67 Supplemental Figure 67 carboxyl terminal 67 GAPDH 67 cystic fibrosis transmembrane conductance 67 miR #a [001] 67 inducible nitric oxide synthase 67 hypoxia inducible factor 67 prostaglandin E 67 phospholipase 67 ERK pathway 67 biotinylated 67 heterodimers 67 VE cadherin 67 Supplementary Fig 67 autophagic 67 protein phosphatase 67 astrocytic 67 iNOS 67 plasmacytoid dendritic cells 67 Fas ligand 67 PLA2 67 cytidine 67 glycogen synthase kinase 67 IL6 67 mediated apoptosis 67 isotypes 67 decarboxylase 67 synthetase 67 Smad3 67 H#K# [002] 67 HIF 1α 67 transcriptional activation 67 substrate specificity 67 dephosphorylation 67 guanosine 67 LNCaP cells 67 glomerular 67 IL 1β 67 mononuclear 67 Secretase 67 caveolin 1 67 CaM 67 NS3 67 cytokine receptor 67 cytosolic 67 c MYC 67 thymidylate synthase TS 67 1α 67 JAK STAT 67 activin 67 CagA 67 K + ATPase 67 immunoreactivity 67 cyclin dependent kinase 67 polyamine 67 integrin alpha 67 PDGFR 67 transgenic mice expressing 67 adrenoceptor 67 microglial activation 67 downregulated 67 DNMT1 67 TIMP 67 nucleolin 67 cAMP 67 virulence genes 67 immunoreactive 67 synthase 67 metalloproteinase 67 ER alpha 67 Clusterin 67 Gly 67 N methyl 67 Sp1 67 proteolysis 67 deoxy 66 induces apoptosis 66 PHD2 66 Rac1 66 downstream effector 66 M1 muscarinic 66 isoforms 66 lyase 66 proteinase 66 PAX5 66 EphB4 66 E cadherin expression 66 bronchial epithelial cells 66 Î ² 66 Activating mutations 66 oncoprotein 66 superoxide dismutase 66 PIP2 66 μM 66 cyclic AMP cAMP 66 proapoptotic 66 Cx# [001] 66 hydrolases 66 ENaC 66 tumor suppressor protein 66 Nedd4 66 eNOS 66 basolateral 66 NFAT 66 c myc 66 N cadherin 66 tyrosine phosphorylation 66 beta actin 66 Cdc# 66 Immunohistochemical analysis 66 Phenylalanine 66 polycystin 66 transfected 66 Macrophage 66 transgene expression 66 aberrantly activated 66 lysates 66 oxidase 66 cytochrome c 66 lysine residues 66 hydroxyphenyl 66 hydrolase 66 uracil 66 monocyte chemotactic protein 66 Notch1 66 IL #p# 66 KLF4 66 Histone 66 pathophysiological effects 66 antiproliferative activity 66 intercellular adhesion molecule 66 splenocytes 66 lymphotoxin 66 null mice 66 immunoblotting 66 alveolar epithelial cells 66 colocalization 66 LRP6 66 phospholipase C 66 Sgk1 66 extracellular signal 66 ,#,# [002] 66 oncogenic transformation 66 nucleolar 66 Fig. 2b 66 DNA methyltransferase 66 deacetylation 66 intracellular pH 66 mediated inhibition 66 glucose transporter 66 γ 66 3' 66 receptor molecule 66 COOH terminal 66 IL 1ß 66 inhibitory activity 66 glutamyl 66 epithelial cells lining 66 NF kappaB activation 66 acinar 66 JAK2 enzyme 66 #S proteasome 66 Cathepsin B 66 phosphatidylinositol 66 neurofilament 66 acyl CoA 66 Mcl 1 66 Gln 66 thioredoxin 66 phosphorylated tau 65 endothelial nitric oxide synthase 65 telomerase reverse transcriptase 65 cysteine protease 65 kinase pathway 65 CD4 + CD# 65 c fos 65 heme oxygenase 65 nitrotyrosine 65 GSTP1 65 myofibroblast 65 potent inhibition 65 HEK# cells 65 CD# CD# 65 hTERT 65 1alpha 65 PIP3 65 IFN γ 65 xenograft tumors 65 ^ sup #m 65 glutathione S transferase 65 MAPKs 65 phosphoinositide 65 LNCaP 65 lysosomal 65 mRNA encoding 65 FGFR1 65 Smad4 65 ß1 65 CYP#A# [002] 65 mediated phosphorylation 65 BCL2 65 protein kinase C 65 coexpression 65 phosphorylase 65 Fig. 1A 65 hepatoma 65 vacuolar 65 phosphatases 65 acyltransferase 65 tyrosine phosphatase 65 cells overexpressing 65 thymidine kinase 65 leukotriene 65 dependent protein kinase 65 cytokine signaling 65 Extracellular 65 fibrogenesis 65 Western blotting 65 5alpha 65 syntaxin 65 tau phosphorylation 65 NFκB 65 Ser# 65 hexose 65 FUS1 65 coactivator 65 upregulates 65 annexin V 65 diacylglycerol 65 upregulation 65 carboxy terminal 65 intronic 65 cytokines IL 65 interleukin IL 65 overexpressing 65 enzymatic activity 65 mPGES 1 65 survivin 65 receptor CD# 65 HIF 1a 65 ubiquitination 65 VEGFR1 65 glucan 65 kD 65 histone acetylation 65 pro apoptotic 65 leukemic cell 65 hyperactivation 65 GTPase 65 c Fos 65 MAPK pathway 65 VEGFR2 65 eIF4E 65 upregulating 65 lymphangiogenesis 65 MnSOD 65 antisense oligonucleotide 65 Synthase 65 dimeric 65 heme oxygenase 1 65 USP# 65 5 HT1A 65 chemoattractant 65 proteolytic cleavage 65 PTPN# 65 SMase 65 inflammatory cytokine 65 nitric oxide synthase NOS 65 tyrosine 65 mimetic peptide 65 proteolytic 65 CCL2 65 Polymorphisms 65 luciferase reporter 65 ubiquitinated 65 Hedgehog signaling 65 tubulin 65 β1 65 Tubulin 65 de novo synthesis 65 mineralocorticoid 65 stably transfected 65 constitutively 65 cyclase 65 TGF b 65 estrogen receptor beta 65 kDa protein 65 gamma H2AX 65 mol L 65 elastase 65 Aß 65 chemokine receptor 65 endocytic 65 amine oxidase 65 p# p# 65 cadherin 65 myc 65 ornithine 64 diphosphate 64 isoenzymes 64 IGF1R 64 metalloprotease 64 PARP1 64 proteoglycan 64 ERK activation 64 retinoic acid receptor 64 factor HGF 64 Fig. 2C 64 5' triphosphate 64 PI3K Akt 64 erythrocytes 64 GLI1 64 defensin 64 ganglioside 64 adipocyte 64 palmitoyl 64 Integrin 64 CYP#B# 64 immunostaining 64 tetramer 64 rRNA 64 EGFR signaling 64 cytochrome P# 64 interleukin IL -# 64 MMP# 64 PPARg 64 HCT# 64 TGF β 64 hnRNP 64 anti inflammatory cytokines 64 melanocyte 64 tRNA synthetase 64 hepatocyte growth 64 β 64 secreted protein 64 NF kappaB 64 renal fibrosis 64 Peyer patches 64 Bcl 64 glucokinase 64 PP2A 64 histidine 64 basophils 64 tyrosine kinase 64 occludin 64 promoter methylation 64 #ß 64 BMAL1 64 muscarinic receptors 64 CYP# [002] 64 p# subunit 64 ciliated 64 neurite outgrowth 64 alveolar macrophages 64 tropomyosin 64 glycoprotein 64 cyclin D1 64 OCT4 64 acetylcholinesterase 64 isoleucine 64 lipid peroxides 64 dsRNA 64 mM NaCl 64 μg ml 64 E3 ligase 64 aminopeptidase 64 MEK ERK 64 c Src 64 hypothalamic pituitary 64 Aâ 64 TNFR 64 transmembrane receptor 64 Arp2 3 64 phosphate dehydrogenase 64 p# Shc 64 phosphorylate 64 adenylyl cyclase 64 receptor gamma 64 acetyltransferase 64 P2X 64 cyclic nucleotide 64 Kupffer cells 64 Fig. 1C 64 ERK phosphorylation 64 Foxp3 64 metalloproteinases 64 MDR1 64 transmembrane 64 BMP signaling 64 imidazole 64 Rho GTPases 64 inhibitory effects 64 actinin 64 cyclin E 64 plasminogen activator inhibitor 64 bradykinin 64 isoprostane 64 anti apoptotic 64 tensin homolog 64 LRP5 64 stably expressing 64 lymphoid cells 64 beta amyloid peptide 64 CXCL# 64 murine 64 antimicrobial peptide 64 adduct 64 methoxy 64 fibroblast 64 vWF 64 Fig. 2c 64 threonine 64 MMP2 64 Cyclin D1 64 adipogenic 64 unmethylated DNA 64 HDAC2 64 acetylcholine receptor 64 perivascular 64 Kir#.# 64 glycosylated 64 IFN g 64 alkaline phosphatase ALP 64 allelic variants 64 acid phosphatase 64 prostaglandin synthesis 64 plasminogen activator 64 phosphorylation 64 C1q 64 hydroxylation 64 Hypoxia Inducible Factor 64 HDACi 64 amino acid residue 64 casein kinase 64 receptor gene 64 cytokine receptors 64 IL #R 64 V#F mutation 64 H#K#me# 64 inhibitory effect 64 monomeric 64 beta2 64 centromeric 64 heterozygotes 64 TrkA 64 E1A 64 Superoxide 64 regulated kinase ERK 64 MAPK 64 COL#A# 64 TrkB 64 receptor kinase 64 TGF ß1 64 Tyrosine 64 transmembrane domain 64 anti apoptotic proteins 64 dinucleotide 64 ERK1 64 oligomerization 64 phosphatidylserine 64 MMP9 64 NFkB 64 SUMOylation 64 galactosidase 64 BMP2 64 TGF alpha 64 subcellular localization 64 steroidogenic 64 ligand receptor 64 trypsin 64 Rho GTPase 64 yl 64 cathepsins 64 mRNA transcripts 64 LRAT 64 presynaptic 64 SOCS3 64 5alpha reductase 64 serine 64 apoptotic pathway 63 Rho kinase 63 ErbB2 63 c MET 63 #β estradiol 63 serpin 63 TAp# 63 HepG2 63 miR #a [002] 63 T#M 63 phagocytosis 63 tryptase 63 cytochromes 63 BCR ABL 63 Huntingtin 63 E3 ubiquitin ligase 63 hematoxylin 63 PC# cells 63 thyroid hormone receptor 63 monocyte 63 ubiquitylation 63 lipopolysaccharide 63 functional polymorphism 63 EF Tu 63 ribonuclease 63 degranulation 63 pyrophosphate 63 polyadenylation 63 sphingosine 1 63 Aβ 63 GlcNAc 63 enterocytes 63 pRb 63 epithelial cell 63 proline rich 63 AMACR 63 topoisomerase II 63 palytoxin 63 TIMP 1 63 transferrin receptor 63 metalloproteases 63 estrogen receptor alpha 63 IFNg 63 replicase 63 adenosine diphosphate ADP 63 miR# 63 mitochondrial biogenesis 63 homozygotes 63 missense mutation 63 kinase domain 63 exonuclease 63 isomerase 63 TLR2 63 globin 63 sphingolipid 63 Fig. 1c 63 Ca2 + 63 GPx 63 ATPase 63 focal adhesion kinase FAK 63 IFN gamma 63 HER2 HER2 63 glycosyltransferase 63 lipopolysaccharide LPS 63 receptor mediated endocytosis 63 ß amyloid 63 cofilin 63 avidin 63 pyrimidines 63 Caveolin 1 63 dioxygenase 63 catalase 63 histone deacetylases 63 FLT3 63 synthases 63 P selectin 63 6S RNA 63 Fig. 2B 63 tyrosinase 63 effector memory 63 CCR1 63 CCL# 63 NADPH 63 peroxynitrite 63 deacetylase 63 apo AI 63 hypomethylation 63 S nitrosylation 63 thrombin receptor 63 aspartate 63 IFN alpha 63 cysteine residues 63 tyrosine residues 63 lymphocyte activation 63 acetyl CoA 63 peroxisomal 63 Phylogenetic analysis 63 miRNA expression 63 cytoplasmic 63 homologue 63 hydroperoxide 63 CFTR cystic fibrosis transmembrane 63 p#NTR 63 CDK4 63 oxidative metabolism 63 WNK1 63 ABL1 63 PGC 1α 63 RAS RAF MEK 63 benzothiazole 63 valine 63 MDA MB 63 Akt activation 63 disulfide bond 63 Alkaline Phosphatase 63 dipeptide 63 Corynebacterium 63 desaturase 63 constitutively activated 63 osteoblast 63 actin polymerization 63 ssDNA 63 immunodominant 63 bcl 2 63 PTHrP 63 importin 63 cyclin 63 Akt 63 plastids 63 Th1 type 63 HLA DR 63 autocrine 63 GABAergic 63 Epithelial 63 N. benthamiana 63 adrenocortical 63 PKC isoforms 63 #,# bis 63 sitosterol 63 postsynaptic 63 costimulatory molecules 63 FGFR2 63 TRAIL receptors 63 alkaline phosphatase 63 Monocyte 63 transmembrane domains 63 MT1 MMP 63 Akt signaling 63 NKX#.# 63 N Myc 63 glutathione GSH 63 ERa 63 PKC delta 63 ESR1 63 CD8 + 63 poly ADP ribose polymerase 63 thymocytes 63 mitogen activated protein kinases 63 missense mutations 63 osteocalcin 63 colony stimulating factor 63 mitochondrial respiration 63 overexpression 63 DLC1 63 GSK 3ß 63 CD#c 63 p# activation 63 5 lipoxygenase 63 IgA antibodies 63 CTGF 63 cofactor 63 RUNX3 63 chloride channels 63 WT1 63 HGF 63 osteoprotegerin 63 PKC enzyme 63 cisplatin resistant 63 E cadherin 63 C EBP 63 cytotoxin 63 nitric oxide synthase 63 overactivation 63 IGF 1R 63 E. faecalis 63 neuroblastoma cells 63 plasminogen 63 orthologous 63 protein p# 63 cyclooxygenase 63 chemokine 63 JNK1 63 apoptotic cells 63 carboxylic acid 63 CEACAM1 63 immunostimulatory 63 Neutrophil 63 β cells 63 deaminase 63 alpha Gal 63 Htt 63 induce apoptosis 63 fig. S1 63 Tyrosine Kinase 63 phospholipase D 63 lacZ 63 HER1 63 ZNF# 63 circadian clock genes 63 BRAF protein 63 RRM1 63 hydrolyzing 63 protein interleukin 63 transcriptional regulation 63 metallothionein 63 PDE#A 63 GABAA receptors 63 peripheral blood mononuclear 63 TRPV4 63 Src kinases 63 Immunohistochemical staining 63 triiodothyronine T3 63 orthologs 63 cytosine 63 oncogenic 63 Protein Kinase 62 glioblastoma cells 62 amino acid residues 62 phagocyte 62 adhesion molecule 62 antioxidant enzyme 62 GNAQ 62 lactone 62 myeloid derived 62 acetylated 62 eotaxin 62 NFkappaB 62 activating mutations 62 glutathione peroxidase 62 PON1 62 E selectin 62 retinoid X 62 colorectal carcinoma 62 Fig. 1a 62 p# alpha [001] 62 ALDH2 62 radiosensitivity 62 demethylation 62 CD# ligand 62 costimulatory 62 clusterin 62 heterodimer 62 caspase activation 62 selectively inhibited 62 glucosides 62 anaphase promoting complex 62 Aurora kinase 62 lung epithelial cells 62 Foxp3 + 62 glycolipids 62 serine proteases 62 transcriptional regulator 62 cyclin B1 62 peptide CGRP 62 5 hydroxytryptamine 62 alpha2 62 IgG antibodies 62 fig. S2 62 TRPV3 62 anti inflammatory cytokine 62 DNA glycosylase 62 Fig. 2a 62 Cytochrome 62 ATP synthase 62 superoxide anion 62 PC3 cells 62 tyrosine hydroxylase 62 apolipoprotein AI 62 splice variant 62 antioxidant glutathione 62 angiopoietin 62 AhR 62 lipid peroxidation 62 Th1 cells 62 transiently transfected 62 TNF receptors 62 enzyme cytochrome 62 selective inhibition 62 p# NTR 62 metabolizing enzymes 62 Heterozygous 62 metaphase 62 FLT3 kinase 62 interleukin IL -6 62 sulfation 62 forkhead 62 phosphate S1P 62 prostate epithelial cells 62 CD4 + T lymphocytes 62 FKBP# 62 Alu RNA 62 HER2 neu 62 TRAF6 62 MDM2 62 tumor suppressor proteins 62 gene encoding 62 Wnt beta catenin 62 H#K# [001] 62 Th2 62 PI3K/Akt 62 mitotic progression 62 TRAIL induced apoptosis 62 FOXO1 62 Reductase 62 transthyretin 62 selectively binds 62 HER2 HER3 62 #S rRNA 62 HCV replicon 62 secretory 62 proline 62 S#A# [002] 62 ß 62 carboxylase 62 ribosomal proteins 62 Cre recombinase 62 goblet cells 62 anterior pituitary 62 IRAK1 62 indole 62 SensoLyte ® 62 transfected cells 62 microsomal 62 glucans 62 autoantibody 62 TSP1 62 Peroxisome proliferator activated 62 labetuzumab 62 dose dependently 62 RNA binding 62 aggrecan 62 RAR beta 62 Oct4 62 potent inducer 62 NF KB 62 leukocyte adhesion 62 apoE 62 beta tubulin 62 cotransporter 62 effector function 62 prion protein PrP 62 cysteines 62 IgG1 62 intracellular signaling 62 CD#L 62 lactamases 62 Mutational 62 MTHFR 62 Src 62 CD3 + 62 malondialdehyde 62 interferon γ 62 GSTT1 62 Vps# 62 TGF beta pathway 62 lytic 62 Transgenic Mice 62 glucosidase 62 ABCA1 62 oligomeric 62 viral nucleic acids 62 triacylglycerol 62 eicosanoid 62 gene encodes 62 Cyclin E 62 β actin 62 PBMCs 62 TRAIL R2 62 gene encodes protein 62 2' 62 antiproliferative effects 62 somatostatin 62 superoxide 62 SH2 domain 62 sensitizer 62 GluR1 62 tumorigenicity 62 transcriptionally 62 rs# [004] 62 FOXP3 62 tubule 62 cell adhesion molecules 62 neuropeptide Y 62 superoxide dismutase SOD