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(Click for frequent words.) 75 phosphorylated 74 acetylation 74 overexpression 73 methylation 73 transcription factor 72 Cdc# 72 Akt 71 mitogen activated protein kinase 70 cAMP 70 enzymatic activity 70 cytosolic 70 signaling pathway 70 transcription factors 70 receptor 70 ubiquitination 70 transcriptional activation 70 dephosphorylation 70 mRNA 70 cyclin D1 69 mRNA expression 69 MAPK 69 beta catenin 69 kinase 69 p# [001] 68 signaling pathways 68 glycosylation 68 E cadherin 68 NF kB 68 estrogen receptor 68 ubiquitylation 68 apoptosis 68 Rac1 68 STAT3 68 catenin 68 proteins 68 proteolysis 67 transcriptional 67 β catenin 67 protein synthesis 67 tyrosine phosphorylation 67 signaling molecule 67 cysteine 67 upregulation 67 Notch signaling 67 cofilin 67 NF kappaB 67 tubulin 67 tumor suppressor 67 caspase 67 tumor suppressor gene 67 tumorigenesis 67 oncogenic 67 GTPase 67 calpain 67 mTOR 67 transactivation 67 phagocytosis 67 ERK1 2 67 isoforms 67 NMDA receptor 66 Src 66 intracellular 66 GAPDH 66 protein kinase 66 histone H3 66 gene expression 66 dimerization 66 PGE2 66 androgen receptor 66 RhoA 66 genes encoding 66 iNOS 66 glucocorticoid receptor 66 Phosphorylation 66 IL 1β 66 receptor activation 66 Wnt signaling 66 transcriptional repressor 66 IL 1beta 66 gene transcription 66 cyclins 66 phosphorylates 66 cadherin 66 enzyme 65 Rab5 65 caveolin 1 65 histone 65 integrin 65 estrogen receptor alpha 65 RANKL 65 gene encoding 65 XBP1 65 ubiquitin ligase 65 PPAR gamma 65 eNOS 65 synthase 65 mRNAs 65 cyclic AMP 65 phosphatase 65 c Myc 65 FasL 65 S nitrosylation 65 kinases 65 DNA methylation 65 GLI1 65 RNA polymerase II 65 NMDA receptors 65 β 65 PAK1 65 NF κB 65 TNFalpha 65 S#A# [002] 65 inhibitory 65 endoplasmic reticulum 65 tumor suppressor genes 65 pRb 65 Myc 65 neuroblastoma cells 65 uPAR 65 ER alpha 65 histone acetylation 65 mitochondrial respiration 65 Skp2 65 Foxp3 65 protein phosphatase 64 phosphorylate 64 Mcl 1 64 Smad3 64 actin cytoskeleton 64 cell motility 64 tumor suppressor protein 64 IGF 1R 64 miR 64 mitochondrial 64 cyclin 64 H#K# [002] 64 Aβ 64 extracellular signal 64 opioid receptor 64 insulin secretion 64 membrane protein 64 upregulated 64 epigenetic silencing 64 ligand 64 endocytosis 64 SIRT2 64 glutamate receptor 64 activin 64 casein kinase 64 NAD + 64 transcriptional regulation 64 protein 64 DNMT1 64 Hedgehog signaling 64 ATPase 64 phosphatidylinositol 64 SIRT1 64 ENaC 64 gamma secretase 64 E3 ligase 64 NFkB 64 SREBP 64 HCV replication 64 BMP signaling 64 phospho 64 oxidative phosphorylation 64 proteases 64 subunit 64 autophagic 64 apoptotic 64 paxillin 64 isoform 64 synaptic transmission 64 BACE1 64 proapoptotic 64 VEGF receptor 64 cell adhesion 64 cytoplasmic 63 downregulation 63 glutamate receptors 63 polyamine 63 anti apoptotic 63 calcineurin 63 protease 63 MEK1 63 STAT1 63 aromatase 63 proto oncogene 63 miRNAs 63 HDACs 63 ß catenin 63 biosynthesis 63 oncoprotein 63 p# MAPK 63 reductase 63 cytokine 63 LRP6 63 intracellular signaling 63 TGF β 63 TGF beta 63 c myc 63 Ca2 + 63 osteocalcin 63 deacetylation 63 HDAC 63 SGK1 63 Bcl xL 63 serine threonine kinase 63 molecular pathway 63 tyrosine kinase 63 MAP kinase 63 FOXO3a 63 intron 63 Rap1 63 microglial 63 muscarinic 63 cytoskeletal 63 PP2A 63 glycolysis 63 adherens junctions 63 Cdk5 63 histone deacetylases 63 presynaptic 63 MyoD 63 cystic fibrosis transmembrane conductance 63 EGFR 63 alpha synuclein 63 matrix metalloproteinase 63 serotonin receptor 63 integrins 63 RUNX3 63 receptors 63 EGF receptor 63 homodimer 63 lipoxygenase 63 clusterin 63 ATF2 63 signaling cascade 63 osteoblast 63 SOD1 63 melanocyte 62 aldosterone 62 epithelial 62 protein kinases 62 evolutionarily conserved 62 HPA axis 62 mitotic 62 TGF ß 62 exocytosis 62 CXCL# 62 PI3K 62 K + ATPase 62 cytochrome P# 62 mTOR signaling 62 EZH2 62 membrane fusion 62 caveolin 62 FGF# 62 c MYC 62 paracrine 62 WT1 62 Nedd4 62 amino acid 62 Runx2 62 ligands 62 TAp# 62 mutant protein 62 oligomerization 62 Nrf2 62 cofactor 62 immunoreactivity 62 miR# 62 downregulated 62 ABCA1 62 IL 1ß 62 RNAs 62 secretion 62 vimentin 62 E#F# 62 SUMOylation 62 autophagy 62 Wnt pathway 62 VE cadherin 62 S1P 62 FAK 62 X inactivation 62 oncogene 62 heterodimers 62 synapse formation 62 IFN gamma 62 cell signaling pathways 62 p#Kip# 62 Vpr 62 enzymatic 62 Nampt 62 E1A 62 p# protein 62 homodimers 62 62 TGF b 62 thioredoxin 62 estrogen receptor beta 62 hypermethylation 62 PDGFR 62 nicotinamide 62 fibronectin 62 oncogenes 62 glutamate 62 S#K# 62 AMPA receptor 62 demethylation 62 Wnt 62 dystroglycan 62 MAPKs 62 Methylation 62 ferritin 62 chromatin 62 ligase 62 PIP2 62 receptor subtype 62 postsynaptic 62 mitosis 62 DNA replication 61 inducible 61 HSP# 61 tyrosine 61 GSK 3ß 61 repressor 61 HIF 1a 61 Kv#.# 61 presenilin 61 NR2B 61 MeCP2 61 proteolytic cleavage 61 TNF α 61 mutant proteins 61 dopamine receptor 61 endothelial cell 61 FOXO 61 survivin 61 regulated kinase ERK 61 ERK signaling 61 overexpressed 61 NFAT 61 MEF2 61 PrP 61 Notch1 61 phosphatidylinositol 3 61 MDM2 61 HIF 1alpha 61 platelet aggregation 61 IRE1 61 gluconeogenesis 61 ERBB2 61 Pin1 61 NRG1 61 prostaglandin E2 PGE2 61 pro apoptotic 61 oxidase 61 Cyclin D1 61 receptor kinase 61 BCR ABL 61 inflammatory cytokine 61 hTERT 61 miRNA 61 Aß 61 CTCF 61 phosphatases 61 receptor molecule 61 neurogenesis 61 substrate specificity 61 receptor tyrosine kinase 61 neurite outgrowth 61 endothelial 61 glycoprotein 61 actin polymerization 61 enzymes 61 TORC2 61 CPEB 61 polymerases 61 GRK2 61 ERa 61 osteoclast activity 61 chromatin structure 61 NFkappaB 61 actin 61 JAK STAT 61 phenotype 61 subunits 61 PIP3 61 protein encoded 61 overexpressing 61 adhesion molecule 61 polyadenylation 61 centromeric 61 NFκB 61 endocytic 61 p# gene 61 polyamines 61 EGFR signaling 61 serine protease 61 myosin 61 Sp1 61 heterochromatin 61 genomic instability 61 TLR4 61 γ 61 molecule 61 tropomyosin 61 apoptotic pathway 61 ADAM# 61 GTPases 61 p# activation 61 cytochrome c 61 catalase 61 polypeptide 61 nNOS 61 mediated phosphorylation 61 Sgk1 61 cyclooxygenase 61 heparan sulfate 61 UCP2 61 microglial activation 61 muscarinic receptors 61 KLF4 61 cyclin dependent kinase 61 palmitoylation 61 metabolic enzymes 61 kinase domain 61 syntaxin 61 LDL receptor 61 B7 H1 61 monocyte 61 peroxisome proliferator activated 61 proteolytic 61 cytoplasmic domain 61 peptide 61 sortilin 61 glycogen synthase kinase 61 proinflammatory 61 cyclin B1 61 inhibitory effect 61 MAPK pathway 61 cytokine secretion 61 CFTR 61 circadian clock genes 60 GRP# 60 p# mitogen activated 60 transmembrane protein 60 adipogenesis 60 P selectin 60 chemokine 60 molecular mechanism 60 inhibition 60 BDNF 60 serine 60 conformational 60 DHFR 60 adenosine 60 neuronal differentiation 60 neuropeptide Y NPY 60 hypoxia inducible factor 60 cell adhesion molecule 60 cytokinesis 60 caspase activation 60 BCL2 60 mTORC1 60 uracil 60 receptor binding 60 glucokinase 60 TGFβ 60 TNFa 60 H#K# [001] 60 nucleosome 60 homologs 60 receptor gamma 60 hnRNP 60 protein kinase C 60 caspases 60 Gln 60 IKKß 60 macrophage 60 chloroplast 60 transferase 60 kinase pathway 60 retinoic acid 60 hypothalamic 60 tyrosine kinases 60 F actin 60 amino terminal 60 cellular pathways 60 EF Tu 60 ACh 60 PGC 1α 60 TRAF6 60 decarboxylase 60 beta arrestin 60 biogenesis 60 overactivation 60 adrenergic receptors 60 Smoothened 60 microglial cells 60 alanine 60 spermatogenesis 60 carcinogenesis 60 lysosomal 60 morphogen 60 signaling molecules 60 Jhdm2a 60 CagA 60 epithelial mesenchymal transition 60 pro angiogenic 60 plasma membrane 60 mice lacking 60 nAChR 60 subcellular localization 60 regulating gene expression 60 hydroxylation 60 RNA splicing 60 cytochrome 60 fatty acid synthase 60 messenger RNA 60 HDAC2 60 SWI SNF 60 transcriptional repression 60 inhibitory effects 60 microRNAs 60 telomeric 60 PPAR alpha 60 tumor suppressor p# 60 ALDH2 60 ERK 60 synthetase 60 secretase 60 constitutively 60 proteoglycan 60 tRNA 60 hyperactivation 60 rRNA 60 dehydrogenase 60 RNA polymerase 60 calmodulin 60 IGFBP 60 beta subunit 60 transferrin receptor 60 Rho kinase 60 induced apoptosis 60 superoxide 60 glycosyltransferase 60 bone resorption 60 mammalian cells 60 vascular endothelial 60 ribosomal 60 dynamin 60 CTLA 4 60 mitochondrial function 60 binding affinity 60 NF kappa B 60 alternative splicing 60 HOTAIR 60 keratinocytes 60 MT1 MMP 60 Rad# 60 apoE 60 Overexpression 60 induce apoptosis 60 centromere 60 endothelial nitric oxide synthase 60 mRNA translation 60 LRRK2 60 RAD# [001] 60 TLR2 60 miRNA expression 60 E3 ubiquitin ligase 60 4E BP1 60 ectopic expression 60 laminin 60 KLF# 60 Rab# 60 CpG 60 constitutively active 60 nucleotide 60 arginase 60 eotaxin 60 ligand binding 60 CTGF 60 beta adrenergic receptors 60 cytoplasmic tail 60 Rho GTPase 60 incretin 60 caveolae 60 microRNA 60 PHD2 60 metabolites 60 neutrophil 60 MnSOD 60 insulin receptors 60 epithelial cell 60 prolyl 60 FKBP# 60 protein phosphorylation 60 serotonin transporter 60 VEGF 60 vascular endothelial cells 60 H#K#me# 60 inflammatory mediators 59 N Myc 59 homolog 59 glucocorticoid 59 myocardin 59 cyclin dependent kinases 59 transcriptionally 59 glycoproteins 59 Bcl 2 59 CatB 59 ACE2 59 IFN γ 59 FGFR3 59 LKB1 59 c Src 59 induces apoptosis 59 H#K# methylation 59 GluR1 59 allosteric 59 synaptic plasticity 59 fibroblast 59 Immunohistochemical analysis 59 genes 59 Th2 59 biochemical pathway 59 histone H4 59 coactivators 59 antioxidant enzyme 59 phosphoinositide 59 Arp2 3 59 chromatin remodeling 59 siRNA mediated 59 Sir2 59 GLUT4 59 fusion protein 59 chromatin remodeling complex 59 acetylcholine receptor 59 BMAL1 59 receptor mediated 59 dopamine receptors 59 gp# [002] 59 coactivator 59 STIM1 59 glycolipids 59 hedgehog signaling 59 matrix metalloproteinases 59 MAP kinases 59 dynein 59 eIF4E 59 lipid metabolism 59 TNFα 59 TNFR 59 exon 59 TGF β1 59 SIRT3 59 c Myb 59 Chk1 59 colocalization 59 FGF2 59 ErbB4 59 BMP4 59 focal adhesions 59 Cx# [001] 59 CaMKII 59 neuronal 59 mitotic progression 59 helicase 59 TGF beta pathway 59 HSCs 59 CEACAM1 59 thyroid hormone receptor 59 proteasome 59 Caspase 59 CB1 receptor 59 dimer 59 signal transduction 59 RKIP 59 superoxide dismutase 59 intracellular calcium 59 inactivation 59 ncRNAs 59 IKKa 59 Stat3 59 Akt activation 59 endogenous 59 oligosaccharides 59 tumor suppressive 59 endoplasmic reticulum ER 59 serine threonine 59 NF kappaB pathway 59 inflammatory cytokines 59 glutamine 59 ubiquitinated 59 nitric oxide synthase 59 Clusterin 59 transgene expression 59 phosphatidylserine 59 PDE5A 59 regulates gene expression 59 #BP# 59 ceramide 59 synaptogenesis 59 catabolism 59 podocytes 59 virulence genes 59 fatty acid oxidation 59 gene 59 p# p# 59 cellular metabolism 59 EBNA1 59 Ago2 59 polypeptides 59 autocrine 59 basolateral 59 tau protein 59 transmembrane 59 epithelia 59 heme oxygenase 59 transcriptional regulator 59 adrenergic receptor 59 cultured cells 59 nucleolin 59 receptor protein 59 methyltransferase 59 ERK1 59 FOXP3 59 endosomal 59 mPGES 1 59 PPARγ 59 KLF2 59 mitochondria 59 AT1R 59 metabolic processes 59 SH2 B 59 metabolic pathway 59 CXCR4 59 melatonin receptor 59 renal fibrosis 59 acetyl CoA 59 phospholipid 59 mutant huntingtin protein 59 Akt signaling 59 neurofibromin 59 AMPA receptors 59 GABAergic 59 hippocampal neurons 59 huntingtin 59 amino acid residues 59 ribozyme 59 LIS1 59 vWF 59 leukemic cell 59 tumor cells 59 downstream effectors 59 cellular senescence 59 FGFs 59 NKT cell 59 LPS induced 59 dimers 59 centromeres 59 μM 59 ß 59 focal adhesion kinase FAK 59 sumoylation 59 transgene 59 gene p# 59 E cadherin expression 59 AChE 59 CDKs 59 TFIIH 59 IL #p# 59 PAX5 59 neuroendocrine 59 apoptotic cells 59 serotonin receptors 59 estrogen receptors 59 Wnts 59 phagocyte 59 IFN alpha 59 nicotinic receptor 59 dehydrogenases 59 CD#b 59 JNK1 58 PLA2 58 IGFBP2 58 RNA molecules 58 Polycomb 58 microtubule 58 PI3K pathway 58 upregulating 58 histone modifications 58 PKM2 58 hepatic stellate cells 58 proinflammatory cytokines 58 HMG CoA reductase 58 striatal 58 antiapoptotic 58 HGF 58 neuropeptide 58 HBx 58 IGF2 58 MMPs 58 FOXO1 58 chemotaxis 58 mTOR pathway 58 PI3K Akt 58 cyclooxygenase COX 58 Akt1 58 somatostatin 58 endonuclease 58 acyltransferase 58 Sirt1 58 molecular pathways 58 5 lipoxygenase 58 malignant transformation 58 kinesin 58 hepcidin 58 kinase gene 58 glioma cells 58 TGF ß1 58 tau phosphorylation 58 operon 58 KaiC 58 Dysregulation 58 ERK pathway 58 triacylglycerol 58 BCL6 58 cell lysis 58 secretory pathway 58 CCL# 58 mutant mice 58 Six3 58 POMC neurons 58 elastase 58 TGF beta1 58 naturally occurring protein 58 leptin receptor 58 glial 58 MAP kinase pathway 58 fibroblasts 58 brain derived neurotrophic 58 p#NTR 58 integrin alpha 58 stromal cells 58 hydrolase 58 RecA 58 amyloid beta 58 tumorigenic 58 methylation patterns 58 valine 58 sphingosine 1 58 cathepsin B 58 ERK2 58 receptor mediated endocytosis 58 methyltransferases 58 vesicle fusion 58 TNF alpha 58 adiponectin 58 RASSF1A 58 neuropeptide Y 58 isoenzymes 58 secretory 58 PDE#A 58 myosin II 58 CYP#E# 58 ARNT 58 plasminogen 58 microRNA molecules 58 Rho GTPases 58 auxin 58 ATP hydrolysis 58 cAMP signaling 58 1α 58 oncogenic transformation 58 VEGFR2 58 Th# cells 58 alternatively spliced 58 TIMP 58 disulfide bond 58 micro RNAs 58 airway remodeling 58 GSK3 58 mutated protein 58 Cathepsin B 58 MUC1 58 Cyclin E 58 regulate gene expression 58 bradykinin 58 cytokine receptor 58 acetylcholine 58 cytosine 58 DNA methyltransferases 58 PKD1 58 ganglioside 58 COOH terminal 58 N methyl 58 NKX#.# 58 monocytes 58 CYP#D# 58 HepG2 cells 58 downstream effector 58 receptor signaling 58 neuronal cell 58 N cadherin 58 ghrelin 58 inducible nitric oxide synthase 58 PECAM 1 58 phosphoprotein 58 costimulatory 58 palladin 58 androgen receptor AR 58 demethylase 58 retinoblastoma protein 58 Saccharomyces cerevisiae 58 neuronal cells 58 nAChRs 58 murine 58 knockout mice 58 PPARg 58 Hedgehog pathway 58 microRNA miR 58 polymerase 58 oxidative 58 inactivating 58 aberrantly activated 58 EGFR protein 58 adenosine receptors 58 amyloid β 58 ErbB2 58 glyceraldehyde 3 58 protein p# 58 interleukin 58 eukaryotic 58 topoisomerase 58 C. elegans 58 mitogen 58 CD# [002] 58 signal transduction pathways 58 signaling cascades 58 histidine 58 SATB1 58 EGFr 58 secreted protein 58 meiotic 58 anti inflammatory cytokine 58 TGFb 58 angiogenic 58 dsRNA 58 5 HT1A 58 progranulin 58 ß1 58 PIK3CA 58 Supplementary Fig 58 Apoptosis 58 beta amyloid peptide 58 HIF 1α 58 PINK1 58 promoter methylation 58 TRIM# 58 intracellular pH 58 transduction 58 hypomethylation 58 lectins 58 pro inflammatory cytokines 58 adrenoceptor 58 hematopoiesis 58 Fas ligand 58 leptin 58 ERK activation 58 non coding RNAs 58 C EBP 58 apoptotic cell 58 TGFß 58 catecholamine 58 γ secretase 58 fission yeast 58 mitotic spindle 58 RBP4 58 retinoic acid receptor 58 heterologous expression 58 cytokine interleukin 58 COX2 57 NKT cells 57 FGFR1 57 PML RARA 57 dopamine transporter 57 EAAT2 57 macrophages 57 ligases 57 neuronal activity 57 P glycoprotein 57 osteopontin 57 miR #a [001] 57 β1