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(Click for frequent words.) 77 kinases 75 signal transduction pathways 75 tyrosine kinases 74 HDACs 73 miRNAs 73 MAPK 72 proteases 72 cellular pathways 72 cell signaling pathways 71 microRNAs 71 tumor suppressor genes 71 phosphatases 71 transcription factors 71 Kinases 71 metabolic enzymes 71 micro RNAs 70 VEGF receptor 70 MAPK pathway 70 mitogen activated protein kinase 70 kinase 70 cell signaling pathway 70 signaling pathways 69 tRNA synthetase 69 FGFR1 69 genes encoding 69 signaling pathway 69 proteins 69 tyrosine kinase 69 cytokine 69 histone deacetylases 69 serine protease 69 NF kappa B 69 cathepsins 69 non coding RNA 69 signaling molecules 69 serine threonine kinase 69 microRNA molecules 69 Fibroblast Growth Factor Receptor 69 noncoding RNAs 69 PI3 kinase 68 cyclin D1 68 protein kinase C 68 protein kinase 68 tumor suppressor protein 68 phosphatidylinositol 3 68 intracellular signaling pathways 68 transmembrane proteins 68 molecular pathway 68 peroxisome proliferator activated 68 microRNAs miRNAs 68 proto oncogene 68 oncogenic 68 TGF beta 68 transcriptional regulation 68 Hedgehog signaling 68 potent inhibitors 68 apoE 68 Hedgehog pathway 68 CDKs 68 Wnt signaling pathway 68 Src 68 NF kB 68 cyclin dependent kinases 68 calcineurin 68 signal transduction 68 cyclins 68 ERBB2 68 Aurora kinases 68 micro RNA 68 c MET 68 pRb 68 MAP kinase 68 IGF 1R 67 PPAR gamma 67 NS5A 67 FGFR 67 ubiquitin ligases 67 cystic fibrosis transmembrane conductance 67 evolutionarily conserved 67 STAT3 67 epigenetic mechanisms 67 binding proteins 67 GPR# [002] 67 oncoproteins 67 Wnt pathway 67 glycosylation 67 histone modifications 67 MDM2 67 NFκB 67 regulating gene expression 67 tumorigenesis 67 p# tumor suppressor 67 small molecule inhibitors 67 hedgehog pathway 67 Smad3 67 serine proteases 67 androgen receptor AR 67 ligases 67 signaling cascades 67 Notch signaling 67 PI3K pathway 67 Akt1 67 PKM2 67 splice variants 67 serine threonine kinases 67 tumor suppressors 67 neurite outgrowth 67 uPAR 67 PAK1 67 KLF4 67 G Protein Coupled 67 oncogenesis 67 tyrosine phosphorylation 67 receptor tyrosine kinase 67 LDL receptor 67 beta catenin 67 miRNA 67 JAK2 67 molecular pathways 67 posttranslational modifications 67 VIPR2 66 immunoregulatory 66 SIRT1 66 biological pathways 66 FLT3 66 FasL 66 ErbB 66 DISC1 66 FGFs 66 NF κB 66 E#F# 66 tumor suppressor gene 66 costimulatory 66 Th# cells 66 Rho GTPases 66 tumor angiogenesis 66 EphA2 66 metalloprotease 66 SIRT2 66 SIRT1 gene 66 missense mutations 66 S1P 66 ERK1 66 dimerization 66 FOXO3a 66 MAP kinases 66 Skp2 66 FGFR2 66 methyltransferases 66 NF kappaB pathway 66 isoforms 66 c MYC 66 mTOR 66 ERK signaling 66 glutamate receptors 66 C5aR 66 encodes protein 66 ERK1 2 66 p#/CBP 66 HDAC 66 phosphorylates 66 paxillin 66 PDGFR 66 interleukins 66 HER3 66 NS4B 66 NF kB pathway 66 Wnt signaling 66 TSP1 66 non coding RNAs 66 chemokines 66 PPARg 66 ERK pathway 66 homodimers 66 adhesion molecule 66 oncoprotein 66 regulates gene expression 66 ubiquitin ligase 65 Arp2 3 65 phosphoinositide 3 65 catenin 65 glycolipids 65 miR #a [002] 65 Sox2 65 Kinase 65 CCR9 65 DNA methyltransferases 65 ion channels 65 thrombospondin 65 GPCRs 65 histone deacetylase 65 melanocortin receptors 65 chemokine receptors 65 Nedd4 65 MicroRNA 65 p# mitogen activated 65 Bcl 2 65 GSK3B 65 PI3K 65 SOD1 65 JAK STAT 65 deacetylation 65 chemokine 65 apoptotic pathway 65 kinase pathway 65 c myc 65 proteins encoded 65 Rap1 65 isotypes 65 Abl 65 protein encoded 65 IL 1β 65 TGF β 65 PI3K Akt 65 tumor suppressor 65 HOTAIR 65 Mcl 1 65 Clusterin 65 cell adhesion molecules 65 IL#R 65 glucocorticoid receptor 65 polyamine 65 eukaryotic 65 PKC isoforms 65 hypermethylation 65 glycoproteins 65 hypoxia inducible factor 65 PIK3CA 65 oncogenic proteins 65 ADAM# 65 secreted protein 65 oncogenes 65 EGFr 65 signaling molecule 65 glioblastoma cells 65 synapse formation 65 SGLT2 65 microRNA expression 65 Kv#.# 65 Stat3 65 intracellular signaling 65 sphingolipid 65 gamma secretase 65 neurofibromin 65 small RNAs 65 dehydrogenases 65 superfamily 65 acetylation 65 inflammatory cytokines 65 sortilin 65 E3 ubiquitin ligase 64 tropomyosin 64 transcriptional activation 64 caspases 64 clusterin 64 ncRNAs 64 JAK3 64 chromosomal regions 64 Dysregulation 64 TMEM#B 64 EZH2 64 ribonucleic acids 64 OCT4 64 WT1 64 membrane receptors 64 lipoxygenase 64 microRNA miR 64 GTPase 64 cytochrome P# 64 ubiquitination 64 intracellular protein 64 protein tyrosine kinase 64 E3 ligase 64 proapoptotic 64 untranslated regions 64 PTPN# 64 vimentin 64 STIM1 64 HER2 HER3 64 genes 64 VEGFR2 64 IL 1ß 64 Wnt 64 receptor gamma 64 substrate specificity 64 casein kinase 64 microRNA 64 beta amyloid peptide 64 GTPases 64 mTOR pathway 64 activin 64 nicotinic receptors 64 p# MAPK 64 EGFR 64 HCV protease 64 adaptive immunity 64 USP# 64 HDAC enzymes 64 Galectins 64 FGF receptor 64 HDAC6 64 Cdc# 64 HDAC inhibitors 64 BCR ABL 64 coding genes 64 GATA3 64 PDGF receptor 64 γ secretase 64 Stat5 64 selective antagonists 64 cell motility 64 EGF receptor 64 IRAK1 64 FGFR3 64 5 lipoxygenase 64 gene expression 64 caveolin 1 64 transcription factor 64 IGFBP2 64 proteolysis 64 receptors EGFR 64 ubiquitylation 64 COX2 64 receptor molecule 64 Eg5 64 transmembrane receptor 64 enzymatic activity 64 protein tyrosine phosphatases 64 β catenin 64 tRNA synthetases 64 lysophosphatidic acid LPA 64 RNAs 64 pDCs 64 ERK2 64 CD#b 64 XIAP 64 aberrantly activated 64 c Myc 64 cyclic AMP cAMP 64 virulence genes 64 Flt3 64 protein tyrosine kinases 64 biogenesis 64 Akt 64 NKT cells 64 selective inhibitors 64 adipogenic 64 oxidative phosphorylation 64 TNF α 64 TGF b 64 circadian genes 63 transcriptional regulators 63 miR #b [002] 63 AT1R 63 Drosha 63 miRNA expression 63 phosphate S1P 63 H#K# [002] 63 Cdc7 63 RAS RAF MEK 63 Chemokines 63 factor receptor FGFR 63 nucleolin 63 KIAA# 63 eotaxin 63 Six3 63 GRP# 63 intracellular proteins 63 NKG2D 63 constitutively expressed 63 transient receptor 63 Phosphorylation 63 NFAT 63 TRP channels 63 axon guidance 63 neuroligins 63 NMDA receptor 63 eukaryotic cells 63 synaptogenesis 63 cyclin dependent kinases CDKs 63 myeloid cells 63 histone acetylation 63 TRAIL induced apoptosis 63 eNOS 63 amino acid residues 63 secretory pathway 63 CagA 63 mTOR signaling 63 BMP2 63 PKD1 63 MicroRNAs 63 ENaC 63 retinoic acid receptor 63 synaptic transmission 63 TRAF6 63 rapamycin mTOR 63 MTHFR 63 chromatin structure 63 causal variants 63 GPR# [001] 63 PcG 63 receptor alpha 63 TNFalpha 63 messenger molecule 63 transcriptional coactivator 63 JAK2 enzyme 63 deacetylase 63 RANKL 63 CXCL# 63 RNA molecules 63 cholesterol metabolism 63 cytokines 63 calpain 63 actin cytoskeleton 63 LRRK2 63 miRNA molecules 63 Rab5 63 B Raf 63 Sirtuins 63 VEGF receptors 63 chaperone protein 63 mRNA expression 63 NFkB 63 membrane protein 63 autocrine 63 major histocompatibility complex 63 ErbB3 63 4E BP1 63 POMC neurons 63 heterodimers 63 selective inhibition 63 TLRs 63 forkhead 63 CK2 63 Hypoxia Inducible Factor 63 homeobox gene 63 IGF IR 63 molecular signaling pathway 63 MiRNAs 63 pre mRNA splicing 63 Hedgehog signaling pathway 63 NAD + 63 CB2 receptor 63 receptors PPARs 63 nAChRs 63 metabolic pathways 63 RNAi pathway 63 molecular biomarkers 63 MMPs 63 tyrosine kinase receptor 63 receptor protein 63 retinoid X 63 GSK 3ß 63 intracellular signal transduction 63 mRNAs 63 TLR8 63 IL 1beta 63 Syk 63 glycosyltransferase 63 PPARγ 63 cell adhesion molecule 63 intracellular pathways 63 ribosomal proteins 63 A3 adenosine receptor 63 PIP3 63 kinase PI3K 63 Fc receptor 63 TORC2 63 kinase domain 63 sRNA 63 HER2 receptor 63 SIRT3 63 apoptosis pathways 63 GPCR targets 63 pro angiogenic 63 gene loci 63 CHD5 63 Protein Kinase C 63 CCR2 63 Histone 63 cytokine receptor 63 isoenzymes 63 selectively inhibits 63 TGF ß 63 GLI1 63 FOXP3 63 glutamate receptor 63 CXCR4 63 mutated genes 63 cytochrome P#s 63 NF kappaB 63 glucocorticoid receptor GR 63 guanosine 63 Huntingtin 63 Oct4 63 neuronal differentiation 63 NNRs 63 LIS1 63 CXCR2 62 phosphorylation 62 Factor Receptor 62 genetic loci 62 histone modification 62 TAp# 62 downregulation 62 serotonin receptor 62 Notch1 62 CTGF 62 Notch pathway 62 SCD1 62 PKC enzyme 62 acetylcholine receptor 62 GPx 62 HCV replication 62 vascular endothelial cells 62 ABCA1 62 receptor tyrosine kinases 62 epithelial tissues 62 Activating mutations 62 potent inhibitor 62 Lyn kinase 62 Caspases 62 Receptors GPCRs 62 synthetase 62 Upregulation 62 RNA sequences 62 drug metabolizing enzymes 62 LRP6 62 CD# ligand 62 phosphoinositide 62 hematopoiesis 62 splice variant 62 induce apoptosis 62 chromatin remodeling 62 HSP# 62 NKX#.# 62 protein phosphorylation 62 phosphatidylinositol 62 MEK1 62 thioredoxin 62 SH#B# 62 virulence determinants 62 lysosomal 62 miRNA genes 62 TERT 62 GABAB receptors 62 biologic pathway 62 ligands 62 TNF receptors 62 galectins 62 invadopodia 62 PKCi 62 adhesion molecules 62 FUS1 62 fusion proteins 62 IL #R 62 TORC1 62 druggable targets 62 tumor suppressive 62 ß catenin 62 syntaxin 62 mRNA molecules 62 adipokines 62 FANCD2 62 histone deacetylase inhibitors 62 glycosylated 62 caveolin 62 IFN gamma 62 glucokinase 62 lipid metabolism 62 secreted proteins 62 Methylation 62 Fibroblasts 62 BCL2 62 K ras mutations 62 mitochondrial gene 62 TGF beta pathway 62 tumor antigen 62 estrogen receptor alpha 62 BCL6 62 ZNF# 62 TXNIP 62 membrane proteins 62 AMPA receptor 62 induces apoptosis 62 anti apoptotic 62 Transcription factors 62 overexpressed 62 multiprotein complex 62 DLC1 62 gene transcription 62 mRNA translation 62 HDAC2 62 miR# 62 phosphorylate 62 cyclin dependent kinase 62 CD1d 62 LSD1 62 FOXO 62 Hh pathway 62 FGF2 62 EGFR signaling 62 polypeptides 62 HOX genes 62 stem cell pluripotency 62 nAChR 62 Foxp3 62 Pten 62 MUC1 62 short hairpin RNAs 62 mutational status 62 thyroid hormone receptor 62 biochemical assays 62 STK# [002] 62 factor BDNF 62 telomerase reverse transcriptase 62 cAMP signaling 62 fatty acid biosynthesis 62 MAP kinase pathway 62 hepatocyte 62 transcriptional repressor 62 Htt 62 HDACi 62 Epidermal Growth Factor 62 p# [001] 62 Oncogenic 62 V#F mutation 62 miR 62 enzymatic reactions 62 RNA splicing 62 Notch receptor 62 chemokine receptor 62 protein tyrosine phosphatase 1B 62 occludin 62 mTOR mammalian target 62 vacuolar 62 serine threonine 62 IKK beta 62 CENP E 62 epigenetic 62 PTP1B 62 biochemical pathway 62 RNA polymerase II 62 vitamin D receptors 62 receptor subtype 62 innate immunity 62 TTR gene 62 miRs 62 CCR3 62 c Myb 62 coupled receptors 62 osteoclast formation 62 5 hydroxymethylcytosine 62 Vascular endothelial growth 62 overexpression 62 PAR1 62 small molecule modulators 62 paralogs 62 Polycomb 62 cyclic AMP 62 tyrosine kinase inhibitors 62 VE cadherin 62 histone deacetylase HDAC 62 CD#L 62 MT1 MMP 62 transferrin receptor 62 survivin 62 tumor microenvironment 62 #HT#A 61 prolyl 61 potent inhibition 61 galectin 61 lipid rafts 61 enzymes 61 Kohwi Shigematsu 61 protein 61 gene expression patterns 61 messenger RNAs 61 androgen receptor 61 Protein Kinase 61 receptor subtypes 61 autism susceptibility genes 61 HMG CoA reductase 61 UCP2 61 sirtuin 61 MEK inhibitors 61 matrix metalloproteinases 61 noncoding RNA 61 Galectin 61 synthases 61 TGF beta1 61 TIR1 61 TH# cells 61 laminin 61 lymphoid 61 regulate gene expression 61 phospholipase A2 61 PI3K AKT 61 protein isoforms 61 presenilin 61 PPAR alpha 61 Integrin 61 extracellular signal 61 Aurora kinase 61 progranulin 61 MyD# 61 TGF Beta 61 miR #a [001] 61 biochemical pathways 61 FGF# 61 genes encode proteins 61 primary cilia 61 circadian clock genes 61 oncogene 61 intracellular 61 DARPP 61 ribonucleic acid RNA 61 PARP inhibition 61 hedgehog signaling pathway 61 coupled receptors GPCRs 61 PHD2 61 somatic mutations 61 neuronal nicotinic receptors NNRs 61 BMP signaling 61 fusion protein 61 Sp1 61 epigenetic alterations 61 Janus kinase 61 ARF1 61 Hsp# [002] 61 hTERT 61 VEGF 61 telomerase RNA 61 peptide antigens 61 BubR1 61 insulin signaling pathway 61 BMP4 61 EphB4 61 MMP9 61 RUNX3 61 LRP5 61 druggable target 61 IRF5 61 bcl 2 61 transmembrane protein 61 PAX5 61 pro apoptotic 61 Overexpression 61 biochemical mechanisms 61 endogenous retroviruses 61 topoisomerases 61 signaling cascade 61 DNA methylation 61 CRAC channel 61 Cathepsin B 61 alpha synuclein 61 Rb#/p# 61 RAS pathway 61 BMAL1 61 Notch receptors 61 Src kinase 61 mTORC1 61 Myc 61 siRNA mediated 61 receptor tyrosine kinases RTKs 61 granzyme B 61 XBP1 61 cytoplasmic domain 61 pro inflammatory cytokines 61 MALAT1 61 serotonin receptors 61 osteoblast 61 S#P# 61 overexpressing 61 HER2 receptors 61 Cyclin E 61 PALB2 61 PON1 61 single stranded oligonucleotides 61 Runx2 61 cAMP 61 cyclin dependent kinase inhibitor 61 homologs 61 gastrin 61 selectively inhibit 61 effector cells 61 Notch signaling pathway 61 microRNAs miR 61 somatostatin 61 Lrp5 61 FoxO1 61 mediating pathological inflammation 61 viral proteins 61 integrins 61 TNF alpha 61 biochemical signaling pathways 61 HLA genes 61 cytokines IL 61 actinin 61 TNFR 61 mRNA sequences 61 Bcr Abl 61 c myb 61 antiapoptotic 61 lincRNAs 61 chromatin remodeling complex 61 T lymphocyte 61 small molecule inhibitor 61 kinase inhibitor 61 N Myc 61 RNA silencing 61 androgen receptors 61 HIF 1α 61 epigenetically 61 HSF1 61 antisense oligonucleotides 61 myelofibrosis polycythemia vera 61 INF2 61 phagocytosis 61 apoE4 61 Rho GTPase 61 enzyme HMG CoA 61 5 HT4 receptor 61 incretin 61 amyloid beta peptide 61 effector functions 61 neurexin 61 Symadex 61 MAPKs 61 Macrophage 61 peptides 61 SWI SNF 61 Wnts 61 microRNA miRNA 61 RAR beta 61 protein misfolding 61 Smurf1 61 RANK ligand 61 intercellular signaling 61 methylation 61 fascin 61 Pim kinases 61 antagomirs 61 CDK9 61 polyamines 61 Hh 61 cytokine signaling 61 PGE2 61 biosynthesis 61 PC# cells 61 enolase 61 PI3K/mTOR 61 cellular metabolism 61 cellular signaling pathways 61 NFkappaB 61 M2 subunit 61 cypin 61 kinase gene 61 SMAD4 61 sPLA2 61 gene mutations 61 downstream effector 61 IgG1 61 K + ATPase 61 trimeric 61 integrin 61 p# activation 61 Mesenchymal 61 DGAT1 61 RKIP 61 B lymphocyte stimulator 61 Abeta peptide 61 Th2 61 T lymphocytes 61 Mutational 61 poly ADP ribose polymerase 61 antibody mediated 61 Wnt beta catenin 61 protein p# 61 NR2B 61 NMDA receptors 61 synuclein 61 IL #p# 60 TNFa 60 neurotrophic factors 60 cholesterol homeostasis 60 Fas ligand 60 transactivation 60 BCR ABL1 60 H#K#me# 60 KLF# 60 myeloproliferative diseases 60 cysteine residues 60 basolateral 60 Adiponectin 60 aromatase 60 genes encode 60 WWP2 60 kinase inhibition 60 subcellular compartments 60 phosphorylated 60 D aspartic acid 60 PTEN gene 60 tau protein 60 sphingosine 1 60 alternative splicing 60 CCL# 60 p# MAP kinase 60 RhoA 60 HERV 60 Alu elements 60 sporadic ALS 60 DNA intercalator 60 coactivator 60 CTCF 60 DLX5 60 Treg cell 60 trans splicing 60 cytoskeletal 60 carbohydrate antigens 60 soluble receptor 60 cell adhesion 60 Polymorphisms 60 piRNAs 60 Ago2 60 CD# molecule 60 matrix metalloproteinases MMPs 60 interferon IFN 60 kinase inhibitors 60 Membrane proteins 60 MEK ERK 60 Aß 60 MSH2 60 ALDH2 60 SATB1 60 kinase PI3K Akt pathway 60 p# protein 60 isoform 60 superoxide dismutase 60 CTLA 4 60 HIF 1alpha 60 renal fibrosis 60 mediated apoptosis 60 protein fragment 60 gene polymorphisms 60 microcephalin 60 fibroblast growth 60 protease 60 IFNs 60 MDSCs 60 soluble fms 60 essential thrombocythemia 60 demethylase 60 molecularly targeted 60 Curaxins 60 neuroinflammation 60 CRF1 receptor 60 breast cancer subtypes 60 TLR3 60 SH2 B 60 messenger RNAs mRNAs 60 estrogen receptors 60 tubulin inhibitor 60 ankyrin repeat 60 ORMDL3 60 PDE#A 60 PPARgamma 60 ERBB4 60 UsiRNAs 60 mesenchymal cells 60 neurotransmitter glutamate 60 BACE1 60 Epidermal Growth Factor Receptor 60 diagnostic biomarker 60 Caspase 60 iNOS 60 histone deacetylation 60 vWF 60 fusogen 60 KRAS oncogene 60 activating mutations 60 selective inhibitor 60 PI3K signaling pathway 60 post transcriptional 60 calcium homeostasis 60 PTP 1B 60 cytochrome P 60 Rab# 60 estrogen receptor 60 factor receptor 60 GPC3 60 CD4 + CD# 60 p# subunit 60 cellular organelles 60 Kinesin 60 telomere maintenance 60 oligomerization 60 protein tyrosine phosphatase 60 neurotrophic