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(Click for frequent words.) 73 caudate 70 gyrus 70 anterior cingulate 68 posterior cingulate 68 medial prefrontal 68 medial temporal 67 dorsolateral prefrontal cortex 67 basal ganglia 66 cingulate 66 parietal 65 rostral anterior cingulate cortex 65 prefrontal 65 inferior frontal 65 gyri 65 middle temporal gyrus 65 caudate nucleus 65 insular cortex 65 orbital frontal cortex 65 temporoparietal 64 entorhinal cortex 64 parietal cortices 64 orbitofrontal cortex 64 lateral orbitofrontal cortex 64 precuneus 64 cortices 64 superior temporal gyrus 64 inferior parietal 64 orbitofrontal 64 striatal 63 anterior insula 63 thalamic 63 somatosensory cortex 63 parietal regions 63 parietal lobes 63 medial frontal 63 globus pallidus 63 ventromedial 63 parahippocampal gyrus 63 medial prefrontal cortex 63 temporal cortex 63 subcortical 63 inferior frontal gyrus 63 cortical regions 62 posterior parietal 62 subgenual cingulate 62 dorsolateral prefrontal 62 hippocampal 62 nucleus accumbens 62 rCBF 62 dorsomedial 62 ventral pallidum 62 ventral striatum 62 orbitofrontal cortex OFC 62 parietal cortex 62 occipital lobes 61 parietal lobe 61 dorsolateral 61 striatum 61 frontotemporal 61 intraparietal sulcus 61 cingulate cortex 61 presynaptic 61 temporoparietal junction 61 midbrain 61 Brodmann Area 61 hyperactivation 61 anterior cortex 61 occipital cortex 61 fronto 61 prefrontal cortical 61 ERK1 2 61 middle frontal gyrus 61 premotor 61 superior temporal sulcus 60 cerebellar 60 Broca area 60 subthalamic nucleus 60 inferior temporal gyrus 60 substantia nigra 60 medial frontal cortex 60 fusiform gyrus 60 hippocampus 60 raphe 60 hippocampi 60 arcuate nucleus 60 Purkinje cells 60 anterior cingulate cortex 60 cortical 60 IL 1ß 59 epithelia 59 paraventricular nucleus 59 mPFC 59 temporal lobe 59 frontal cortex 59 lateralized 59 angular gyrus 59 NMDA receptors 59 fractional anisotropy 59 D2 receptor 59 receptor subtype 59 hippocampal neurons 59 lateral habenula 59 muscarinic receptors 59 dorsal striatum 59 prefrontal brain 59 dopamine receptors 59 posterior parietal cortex 59 hypothalamic 59 hypometabolism 59 ventromedial prefrontal cortex 59 inferior parietal lobule 59 mesolimbic 58 prefrontal cortex 58 limbic 58 CD#b 58 frontal parietal 58 pre frontal cortex 58 medial orbitofrontal cortex 58 amygdala 58 DLPFC 58 hippocampal formation 58 detrusor 58 pulvinar 58 cingulate gyrus 58 perirhinal cortex 58 lateral ventricle 58 posterior temporal 58 dorsal anterior cingulate cortex 58 motoneurons 58 forebrain 58 transmembrane protein 58 fronto temporal 58 autophagic 58 innervated 58 cerebral cortical 58 N acetylaspartate 58 hypothalamic pituitary 58 anterior temporal 58 amygdalae 58 Wnt signaling 58 primary visual cortex 58 temporal parietal 58 myelinated 58 posterior cingulate cortex 58 prefrontal cortex PFC 58 eNOS 58 hypothalamus pituitary 58 mu opioid 58 postsynaptic 58 lateral hypothalamus 57 neuropeptide Y 57 anterior cingulate gyrus 57 basal forebrain 57 planum temporale 57 c Fos 57 medial temporal lobe MTL 57 ERK signaling 57 hyperintensity 57 vasopressin receptors 57 Prefrontal 57 periventricular 57 corpus callosum 57 hypoperfusion 57 cortex 57 pyramidal neurons 57 BMP signaling 57 T2 weighted images 57 #HT#A 57 ventral 57 cortico 57 parahippocampal 57 adrenal cortex 57 nAChR 57 vermis 57 IL 1beta 57 contractility 57 dopamine signaling 57 autocrine 57 K + ATPase 57 amygdale 57 thalamus 57 innervation 57 occipital 57 myocytes 57 glomerular 57 inferior parietal cortex 57 acetylcholine receptor 57 myometrium 57 catenin 57 paracrine 57 corticospinal tract 57 HPA axis 56 temporal lobes 56 somatosensory 56 occipital lobe 56 premotor cortex 56 insula 56 piriform cortex 56 ERalpha 56 myocardial tissue 56 frontal lobe 56 TRPV1 receptors 56 noradrenergic 56 downregulate 56 ventrolateral 56 myocyte 56 afferent 56 serotonergic 56 endocrine glands 56 tau protein 56 protein kinase C 56 dorsal horn 56 nitric oxide synthase 56 mRNA expression 56 MAP kinase 56 circadian clock genes 56 neuromuscular junction 56 efferent 56 left ventricular diastolic 56 hormone secretion 56 cell adhesion molecule 56 vasodilatation 56 IL #p# 56 proinflammatory mediators 56 cortical thickness 56 dopaminergic 56 synaptic vesicles 56 hepatic stellate cells 56 rostral 56 SLC#A# [002] 56 noradrenaline 56 nucleus accumbens NAc 56 dendritic spines 56 primary somatosensory cortex 56 prefrontal lobes 56 S#A# [002] 56 dopamine D2 receptor 56 hindbrain 56 PECAM 1 56 cortical neurons 56 glutamatergic neurons 56 AMPA receptors 56 atrioventricular 56 Aß 56 subcortical structures 56 medial temporal lobe 56 tyrosine hydroxylase 56 brain derived neurotrophic 56 microglial 56 glutamate receptor 56 myofibroblasts 56 glial 56 dentate gyrus 56 NAcc 56 ACh 56 morphogen 56 VE cadherin 56 NAc 56 Smad4 56 excitatory signals 56 baroreceptor reflex 56 parenchyma 56 apical 56 autoregulation 56 receptor gene 55 extracellular signal 55 5 HT1A 55 granule cells 55 cortexes 55 lateral prefrontal cortex 55 endoplasmic reticulum ER 55 fusiform 55 beta endorphin 55 estrogen receptor alpha 55 dopamine transporter 55 inhibitory 55 TrkB 55 dorsal prefrontal cortex 55 habenula 55 synaptic plasticity 55 neuronal cell 55 gene polymorphisms 55 Purkinje cell 55 rACC 55 hyperalgesia 55 immunoreactive 55 neurite outgrowth 55 sensorimotor cortex 55 striatal dopamine 55 synaptic function 55 cyclic AMP cAMP 55 corticotrophin releasing hormone 55 proinflammatory cytokines 55 tubule 55 dysregulated 55 inhibitory neurotransmitters 55 isoenzyme 55 mitochondrial respiration 55 sensorimotor 55 osteoblast 55 transmembrane 55 caveolin 1 55 contralateral 55 excitatory neurotransmitter 55 atherosclerotic lesions 55 ventral tegmental area 55 immunoreactivity 55 anterior pituitary 55 inducible nitric oxide synthase 55 ipsilateral 55 microglial activation 55 hypothalamic pituitary adrenal axis 55 HIF 1a 55 infarcted 55 mitogen activated protein kinase 55 neurite 55 locus coeruleus 55 subthalamic nucleus STN 55 ERK pathway 55 parenchymal 55 constitutively 55 AMPA receptor 55 epididymal 55 beta adrenergic receptors 55 prefrontal regions 55 TIMP 1 55 endogenous cannabinoids 55 neuronal migration 55 Kupffer cells 55 vasodilation 55 prefrontal lobe 55 β catenin 55 CaM 55 acinar 55 downregulation 55 CB1 receptors 55 serotonin synthesis 55 sensory cortex 55 thyrotropin 55 kinase domain 55 acyl CoA 55 TNFalpha 55 IL6 55 serotonin neurons 55 ventral prefrontal cortex 55 astrocytic 55 BDNF gene 55 lateral ventricles 55 POMC neurons 54 pro inflammatory cytokine 54 Ca2 + 54 neocortical 54 periaqueductal gray 54 secretory 54 ouabain 54 auditory cortex 54 interneurons 54 cerebellum 54 encodes protein 54 GH secretion 54 sulcal 54 GABAergic interneurons 54 HepG2 cells 54 lipid rafts 54 olfactory bulb 54 beta subunit 54 contractile function 54 vasopressin 54 synaptic transmission 54 podocyte 54 adhesion molecule 54 laterality 54 IFN γ 54 gamma oscillations 54 progranulin 54 sulcus 54 basolateral 54 cyclic AMP 54 vasoconstriction 54 neuronal signaling 54 pyramidal cells 54 GABAA receptors 54 sortilin 54 echogenicity 54 oligomerization 54 osteoblastic 54 #ß 54 cytosol 54 FDG uptake 54 ectopic expression 54 junctional 54 opiate receptors 54 opioid receptor 54 glomerulus 54 platelet activation 54 intercellular communication 54 acetylcholine receptors 54 mediastinum 54 hypothalamus 54 oncogenic transformation 54 Aâ 54 proto oncogene 54 potentiation 54 PDGFR 54 IKKß 54 glia cells 54 ventrolateral prefrontal cortex 54 cerebral hemispheres 54 aspartate aminotransferase AST 54 secretory cells 54 Brain derived neurotrophic 54 olfactory cortex 54 degenerating neurons 54 amyloid deposits 54 D aspartate 54 Hedgehog signaling 54 WNK1 54 pineal 54 toxic amyloid beta 54 CA1 54 cysteines 54 mesenteric 54 vagus 54 Rap1 54 medulla 54 astrocyte 54 F actin 54 medial temporal lobes 54 Acetylcholine 54 PIP2 54 postsynaptic neuron 54 Abeta# 54 renal fibrosis 54 conduction velocity 54 locomotor activity 54 p# MAPK 54 SVZ 54 hamartomas 54 adrenocortical 54 receptor subunit 54 neuropeptides 54 β amyloid 54 perfused 54 NMDAR 54 hypothalamic pituitary adrenal HPA 54 functional polymorphism 54 CaM kinase II 54 factor BDNF 54 sGC 54 cytokine signaling 53 downregulated 53 brain limbic 53 Hh 53 frontal temporal 53 metaphase 53 STAT1 53 myogenic 53 nAChRs 53 lateralisation 53 paxillin 53 demyelination 53 hippocampal cells 53 CXCL# 53 mice lacking 53 capillary density 53 Fig. 1D 53 capillary endothelial cells 53 cerebellar vermis 53 amyloid β 53 excitatory synapses 53 neurotransmitter receptors 53 deacetylation 53 Aß# 53 P selectin 53 transcriptional activation 53 upregulated 53 visual cortex 53 FGFs 53 monocyte 53 calcium homeostasis 53 dorsal root ganglia 53 brain hypothalamus 53 major histocompatibility complex 53 synaptogenesis 53 baroreceptor 53 intima media thickness 53 N methyl 53 mesoderm 53 excitatory neurotransmitter glutamate 53 exocytosis 53 metabolizing enzyme 53 CD# + [001] 53 opioid receptors 53 5 hydroxytryptamine 53 axon guidance 53 TRPV4 53 adenylate cyclase 53 μ opioid receptor 53 Macrophage 53 TGF β 53 pro angiogenic 53 neuritic plaques 53 podocytes 53 epithelial cell 53 perivascular 53 nitric oxide synthase NOS 53 dendritic spine 53 N cadherin 53 cell adhesion molecules 53 cerebral cortex 53 P cadherin 53 nNOS 53 amyloid deposition 53 DISC1 53 c fos 53 radial glia 53 adenosine diphosphate ADP 53 tyrosine phosphorylation 53 endoplasmic reticulum 53 glomeruli 53 Leydig cell 53 chromosome #q#.# [001] 53 afferents 53 thyroglobulin 53 neuropeptide Y NPY 53 lysophosphatidic acid 53 suprachiasmatic nucleus 53 dopamine pathways 53 synapse maturation 53 cytosolic 53 excitatory 53 vasomotor 53 neurotransmitters serotonin 53 DARPP 53 neuron 53 mu opioid receptors 53 catecholamine 53 plasma membrane 53 accumbens 53 brainstem 53 caspase activation 53 Ki# 53 amyloid beta plaques 53 neuronal differentiation 53 guanosine 53 inhibitory transmitter 53 rs# [002] 53 cannabinoid receptors 53 corticotropin releasing factor 53 apoE4 53 Cdc# 53 FGF2 53 DNMT1 53 striated muscle 53 neovascularization 53 HUVEC 53 Sgk1 53 alkaline phosphatase 53 myofibroblast 53 ATPase 53 contractile 53 procaspase 3 53 splanchnic 53 transduced 53 monoamine 53 CHI#L# 53 Prolactin 53 tumoral 53 ER alpha 53 urinary excretion 53 sensory nerves 53 PIP3 53 actin binding 53 mitogen activated protein kinases 53 intraventricular 53 lymph node metastasis 53 echogenic 53 c Src 53 retinal neurons 53 enkephalins 53 FasL 53 receptor subtypes 53 neuroendocrine 53 D2 receptors 53 isoenzymes 53 Hypothalamic 53 fractional shortening 53 astrocytes 53 nicotine receptor 53 Src kinase 53 ERK activation 53 gamma aminobutyric acid 53 CEACAM1 53 seminomas 53 inflammatory cytokine 53 demyelinated 53 ß catenin 53 hormone vasopressin 53 GSTP1 53 motor cortex 53 neurotransmitters dopamine 53 methyl D aspartate 53 secreted protein 53 calpain 53 Wnt pathway 53 basolateral amygdala 53 serotonin receptors 53 CDH# 53 neurofibrillary tangles 53 cytoskeletal 53 Notch receptor 53 myo inositol 53 XPB 53 cortical thinning 53 mitogenic 53 VEGF receptor 53 mdx mice 53 interstitium 53 neuronal nitric oxide synthase 52 TNF α 52 dopamine D2 52 CD#c 52 Abnormalities 52 cadherin 52 macrophage infiltration 52 VEGF expression 52 cardiac fibroblasts 52 penile erection 52 superior temporal cortex 52 VMPC 52 mesenchyme 52 glutamatergic 52 NR2B 52 serine proteases 52 NMDA receptor 52 anterior prefrontal cortex 52 cyclooxygenase 2 52 GABA receptor 52 histologically 52 Src kinases 52 Clusterin 52 plasminogen activator inhibitor 52 NKG2D 52 rs# [004] 52 hematopoietic cells 52 phagocytosis 52 TRPV3 52 Dpp 52 RhoA 52 serotonin receptor 52 nitrotyrosine 52 intestinal epithelium 52 S nitrosylation 52 medial prefrontal cortex mPFC 52 homodimer 52 Dysregulation 52 ligand receptor 52 5 HT2A receptor 52 costimulatory molecules 52 MyD# 52 PI3K Akt 52 upregulates 52 anterior temporal lobe 52 phosphoinositide 52 dysregulation 52 neuronal circuits 52 dopamine neuron 52 circadian pacemaker 52 transcriptional repressor 52 constitutively active 52 carbohydrate metabolism 52 cortical activation 52 neural pathway 52 leptin receptor 52 adipogenic 52 baroreflex 52 neurotransmission 52 Rac1 52 ceruloplasmin 52 lipoprotein lipase 52 endothelial nitric oxide synthase 52 CYP#B# 52 norepinephrine 52 extracellular calcium 52 EGFP 52 p#NTR 52 elastase 52 myoepithelial cells 52 vacuolar 52 endocytosis 52 steroidogenic 52 serotonin transporter 52 Aβ 52 autonomic nerves 52 pituitary hormone 52 electrical conduction 52 suprachiasmatic nucleus SCN 52 endogenous opioid 52 left ventricular LV 52 ciliary 52 endothelial cell 52 raphe nucleus 52 cerebral hemisphere 52 proinflammatory cytokine 52 overactivity 52 prostaglandin E2 52 synaptic vesicle 52 p# activation 52 DMT1 52 steroidogenesis 52 TGF ß1 52 PON1 52 vWF 52 TGF ß 52 neuronal activity 52 proinflammatory 52 Wnt 52 caveolae 52 adrenoceptor 52 erythroid 52 NADPH oxidase 52 systolic function 52 prostate epithelial cells 52 electroencephalographic 52 alpha subunit 52 isoforms 52 limbic system 52 regulates gene expression 52 occipital regions 52 subventricular zone 52 neurosteroid 52 Notch signaling pathway 52 motor neuron degeneration 52 hippocampal volumes 52 brain frontal lobe 52 H#K#me# 52 eicosanoids 52 bronchoalveolar lavage fluid 52 homozygotes 52 brain parenchyma 52 M1 muscarinic 52 glutamate receptors 52 neuronal cells 52 PHD2 52 serotonergic neurons 52 dopamine norepinephrine 52 Runx2 52 GABA gamma aminobutyric acid 52 epithelium 52 remyelination 52 almond shaped structure 52 microvessels 52 regulated kinase ERK 52 inhibitory synapses 52 inhibitory neurotransmitter 52 anatomic structures 52 atherosclerotic lesion 52 HuR 52 MnSOD 52 circadian genes 52 protein tyrosine kinase 52 infarct 52 huntingtin 52 neuroligins 52 Fig. 1A 52 upregulation 52 pontine 52 adhesion molecules 52 JAK STAT 52 MEF2 52 5 HT2C receptor 52 downregulates 52 methylation patterns 52 peripheral tissues 52 IRS1 52 Thyroid hormone 52 SUMOylation 52 cholinergic 52 axonal 52 neurones 52 toxic beta amyloid 52 iNOS 52 activated microglia 52 lactate dehydrogenase 52 vagal 52 microtubule dynamics 52 subthalamic 52 corticospinal 52 excitatory neurons 52 endogenous opioids 52 aldehyde dehydrogenase 52 neuritic 52 pDCs 52 Astrocytes 52 alanine aminotransferase ALT 51 leukocyte infiltration 51 pulse amplitude 51 PAK1 51 malignant prostate 51 effector memory 51 BMP4 51 spermatogenesis 51 ependymal cells 51 adrenal medulla 51 interleukin IL -6 51 corticotropin 51 dehydrogenase 51 fig. S1 51 Akt 51 voxel 51 dopamine 51 dorsolateral prefrontal cortex DLPFC 51 Fig. 2b 51 LKB1 51 lacrimal glands 51 VEGFR1 51 tDCS 51 neurogenesis 51 vascular endothelial 51 anterior hypothalamus 51 cardiac myocytes 51 MMP# 51 microglial cells 51 lesional 51 goblet cells 51 LV ejection fraction 51 neuronal dysfunction 51 EGFr 51 neurone 51 Cx# [001] 51 dephosphorylation 51 TLR4 51 casein kinase 51 CXCR2 51 HOX genes 51 Supplementary Fig 51 vascular endothelial cells 51 GLI1 51 Elevated serum 51 beta amyloid plaque 51 striata 51 kappa opioid receptors 51 Androgen receptor 51 PDGF receptor 51 p# mitogen activated 51 GABAergic 51 MMP2 51 neuropathological 51 brain hemispheres 51 Cathepsin B 51 agonist induced 51 ChR2 51 cypin 51 embryonic tissues 51 Rb#/p# 51 neuronal synapses 51 trigeminal ganglion 51 epididymis 51 glucocorticoid 51 phosphorylates 51 Oxidative stress 51 MAPKs 51 myelinated axons 51 amyloid beta peptides 51 Alzheimer disease pathology 51 neurotrophic 51 infarcts 51 acetylcholine 51 uPAR 51 bradykinin 51 LRP6 51 osteogenic differentiation 51 mitochondrial oxidative 51 inhibitory interneurons 51 myelination 51 neuronal plasticity 51 adipokines 51 Inhibitory 51 PC# cells 51 adenosine receptors 51 neurotransmitter dopamine 51 osteoclast formation 51 mitochondrial membrane 51 raphe neurons 51 AgRP 51 lymphovascular invasion 51 H2AX 51 cathepsins 51 PACAP 51 trabeculae 51 senile plaques 51 = -#.# 51 fibrillin 51 peroxisomal 51 N myc 51 white matter hyperintensities 51 euthymic patients 51 factor PlGF 51 TRPV1 51 neurons 51 proteolytic cleavage 51 NF KappaB 51 synaptic 51 actin polymerization 51 potassium ion 51 opioid peptides 51 IRE1 51 BDNF protein 51 #q# [001] 51 receptor gamma 51 glia 51 bile acid 51 protease activated 51 inverse agonist 51 beta arrestin 51 fibrin deposition 51 amyloid beta plaque 51 genu 51 brown adipose tissue 51 inferior frontal cortex 51 neurotransmitter 51 #HT#A receptor 51 GLUT4 51 Insulin sensitivity 51 diffusion tensor 51 E cadherin 51 orexin neurons 51 emotional arousal 51 cholesterol efflux 51 sinus node 51 sensory neurons 51 ERBB2 51 Lyn kinase 51 histone modifications 51 intact parathyroid hormone 51 mesenchymal cells 51 CB1 receptor 51 thicker cortex 51 cognitive affective 51 ENaC 51 cytochrome c oxidase 51 BDNF 51 brain lesions 51 heme oxygenase 51 CaMKII 51 LRP1 51 MDM2 51 brain cortex 51 neuronal apoptosis 51 amyloid peptides 51 dysbindin 51 gene encoding 51 Androgen 51 Fig. 3a 51 mitogen 51 nicotinic receptor 51 melanocyte 51 osteoclast 51 hematopoietic progenitor cells 51 pharyngeal 51 skeletal muscle cells 51 blood oxygenation 51 HIF 1α 51 lipid homeostasis 51 dimers 51 superior frontal gyrus 51 Sp1 51 Fig. 4B 51 muscarinic receptor 51 transduction 51 apoE 51 GPR# [002] 51 homodimers 51 anti inflammatory cytokine 51 cholinergic tone 51 transcriptional regulation 51 intracellular calcium 51 FKBP# 51 overexpressing 51 RIP1 51 nociceptive 51 hypothalamus gland 51 p#Kip# 51 corticotropin releasing hormone 51 acetyl CoA 51 PGC 1α 51 lung epithelium 51 mirror neuron 51 redox 51 catechol O methyltransferase 51 Myosin II 51 SMAD4 51 COMT 51 neuropeptide 51 mitochondrial enzyme 51 ischemia induced 51 melatonin receptors 51 PGE2 51 neuro transmitter