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(Click for frequent words.) 62 quantitation 61 quantifying 61 Quantification 58 reproducible measurements 55 biomolecular interactions 55 measurement 55 colorimetric 55 quantitative PCR qPCR 54 histopathological 54 quantifications 54 quantitative 54 quantitative measurements 54 sensitivity specificity 54 microRNA profiling 53 RT qPCR 53 putative biomarkers 52 powder diffraction 52 cytologic 52 mass spectrometric 52 Reproducibility 52 Prognostic 52 electrospray ionisation 52 semiquantitative 52 Flow cytometry 52 physico chemical 51 immunohistochemistry IHC 51 assay ELISA 51 precise quantification 51 particle morphology 51 iTRAQ 51 liquid chromatographic 51 interobserver 51 quantitate 51 spectrophotometric 51 correlation coefficients 51 biomarker 51 bioinformatic analysis 51 immunohistochemical 51 quantitative polymerase chain 51 reaction kinetics 51 2D gel electrophoresis 51 phenotyping 51 protein quantitation 51 RNA extraction 51 chromatograms 51 Quantitation 51 genotypic 51 kinase assay 51 biomarkers 51 mass spectroscopy 51 protein ligand 50 PCR RFLP 50 quantify 50 PCR amplification 50 qRT PCR 50 Mass Spectrometry MS 50 metabolite concentrations 50 gDNA 50 reverse transcriptase polymerase chain 50 calorimetric 50 prognostically 50 F FDG PET 50 Western blotting 50 multiplexed assays 50 multivariate statistical 50 bioassays 50 ChIP chip 50 quantitative proteomics 50 prognostic indicators 50 morphometry 50 immunoblot 50 metabolite identification 50 SiMoA 50 nanoflow 50 metabolite profiling 50 xenobiotic 50 microarray gene expression 50 Probabilistic 50 proton MR spectroscopy 50 flow cytometric 50 interobserver agreement 50 eigenvalue 50 metabolomics 50 proteomic analysis 50 #S rRNA gene 50 asymmetric catalysis 50 immunohistochemical analysis 50 dosimetric 49 quantitative RT PCR 49 transcriptome analysis 49 fluorescence imaging 49 reverse transcription polymerase 49 attenuation correction 49 multiparametric 49 reproducibility 49 chemometrics 49 allelic 49 mass spectrometric analysis 49 chemosensitivity 49 MSn 49 biomarker identification 49 surface plasmon resonance SPR 49 QPCR 49 FDG-PET/CT 49 LC-MS/MS 49 prognostic marker 49 nucleic acid isolation 49 clinicopathological features 49 preanalytical 49 analyte 49 enzyme kinetics 49 nucleic acid sequence 49 DEV DA TOMAR NEXT 49 transgene expression 49 urine cytology 49 phenotypic expression 49 DNA demethylation 49 etiologic 49 MALDI-TOF/TOF 49 surrogate markers 48 bacterial genomes 48 eTag assays 48 quasispecies 48 LTQ Orbitrap XL 48 Cyclin E 48 MALDI imaging 48 bisulfite sequencing 48 multiplex PCR 48 serum biomarkers 48 deconvolution 48 transabdominal 48 Immunohistochemical 48 metabolome 48 prognostic 48 FISH fluorescence 48 physicochemical 48 MALDI MS 48 fluorescence spectroscopy 48 transcriptomics proteomics 48 genotyping 48 genomic alterations 48 quantitative PCR 48 Colorimetric 48 tumorigenicity 48 iterative reconstruction 48 Polymerase Chain Reaction 48 reproducible 48 reaction PCR 48 Estimation 48 Molecular imaging 48 nanoscale characterization 48 Annexin V 48 ELISA assays 48 PNA FISH TM 48 photobleaching 48 Orbitrap 48 PET tracers 48 RT PCR 48 genomewide 48 fluorescence detection 48 proteome 48 Repeatability 48 nodal dissection 48 FDG PET imaging 48 FDG PET 48 spectroscopic technique 48 functional annotation 48 ELISA assay 48 ChIP seq 48 splice variants 48 proteomic 48 radiolabeling 48 cDNA synthesis 48 multiplex assays 48 FDG PET scans 48 quantitatively 48 mutagenicity 48 micrometastasis 48 RNA sequencing 48 NMR experiments 48 transcriptomes 48 D Dimer 48 NIR spectroscopy 48 perfusion imaging 48 dimensional nanostructures 48 gene amplification 48 helical CT 48 IntroductionThe 48 Raman spectra 48 artifactual 48 covariance 48 transient elastography 47 miRNA expression profiling 47 transvaginal sonography 47 post translational modifications 47 Characterization 47 nested PCR 47 quantitative gene expression 47 fluorimetry 47 genomic biomarkers 47 pharmacodynamic PD 47 circular dichroism 47 multiplex assay 47 array CGH 47 Western Blotting 47 detectability 47 experimentally verified 47 quantitative reverse transcriptase 47 transcriptomics 47 metabolomic 47 colonoscopic 47 situ hybridization 47 Alkaline Phosphatase 47 capillary electrophoresis CE 47 pleural fluid 47 proteolytic activity 47 metabolomic profiling 47 Correlative 47 HLA genotyping 47 ELISAs 47 qNPA 47 differential gene expression 47 immunotoxicity 47 PITX2 47 Bayesian inference 47 isotope dilution 47 subcellular localization 47 surrogate marker 47 cytometry 47 immunofluorescent 47 biomarker discovery 47 Gene Ontology 47 HER2 expression 47 endpoint assays 47 #F FDG PET 47 recursive partitioning 47 biomarker assays 47 MDRD 47 tracer uptake 47 Quantitative PCR 47 antibody antigen 47 biomolecular interaction 47 tumor hypoxia 47 nucleic acids proteins 47 immunoblotting 47 transcriptional regulation 47 elemental composition 47 interobserver reliability 47 BaP 47 intraobserver 47 IVIVC 47 DNA Polymerase 47 dosimetry 47 chromatographic 47 #S rDNA 47 Lymph node 47 coronary CT angiography 47 diagnostic 47 induced sputum 47 pathologic diagnosis 47 meta analytic 47 Sanger sequencing 47 pleiotropy 47 pelvic lymphadenectomy 47 Cardiorespiratory fitness 47 Lavastorm Analytic Platform 47 IR spectra 47 synthesis 47 comparative genomic hybridization 47 plasma mass spectrometry 47 Cdc7 47 linearization 47 sub micron particles 47 brightfield microscopy 47 transcriptomic 47 Phenotypic 47 TOF TOF 47 hERG 47 reaction RT PCR 47 malignant nodules 47 surface plasmon resonance 47 nonparametric 47 X ray absorption spectroscopy 47 transcriptome 47 distributional impacts 47 cell lysis 47 epigenomic 47 PDZ domains 47 immunochemical 47 Preoperative 47 PCR assay 47 cTnI 46 PD2i ® 46 multivariate regression 46 Accurately measuring 46 genomic DNA 46 assay detects 46 hilar 46 chromatin immunoprecipitation 46 chemiluminescence 46 prognostic markers 46 lysate 46 positron emission 46 Heterogeneity 46 vivo 46 molecular assays 46 gene expression microarrays 46 lactate dehydrogenase 46 ultrasonographic 46 radiation dosimetry 46 MALDI TOF mass spectrometry 46 urothelial carcinoma 46 antigen antibody 46 prostatic fluid 46 bone scintigraphy 46 massively parallel sequencing 46 probabilistic modeling 46 classificatory 46 ChIP Seq 46 hemodynamic variables 46 immunohistochemical staining 46 multiphoton microscopy 46 adjuvant therapies 46 stratifying patients 46 physico chemical properties 46 apolipoproteins 46 fluorescence excitation 46 metabonomics 46 spectrophotometry 46 accurate quantitation 46 quantified 46 complexation 46 comparative genomic 46 cystoscopic 46 NPV IRR 46 spectrometric 46 nonzero 46 flow cytometry 46 perfusion CT 46 biothreat agents 46 molecular biomarker 46 methodologic 46 immunomagnetic separation 46 mediated inhibition 46 haplotyping 46 kinase assays 46 HPV genotyping 46 Cystatin C 46 qPCR 46 predictive biomarker 46 Immunohistochemical staining 46 FT IR 46 electron beam computed tomography 46 Mass spectrometry 46 peripheral insulin sensitivity 46 preoperative diagnosis 46 oligonucleotide microarrays 46 computed tomographic scans 46 PCWP 46 qPCR assay 46 multiplexing capability 46 RQ PCR 46 fluorescence quenching 46 waist circumference WC 46 SurePrint 46 pharmacodynamic parameters 46 RNA Seq 46 mucinous 46 genotype phenotype 46 proteomes 46 PITX2 methylation 46 proteomic analyzes 46 observable traits 46 echocardiographic parameters 46 evolvability 46 covariate 46 genomic biomarker 46 silico modeling 46 Liquid chromatography 46 APTIMA HPV 46 handheld XRF 46 protein biomarkers 46 cardiometabolic syndrome 46 LC MALDI 46 molecular biomarkers 46 Poisson regression 46 predictive 46 messenger ribonucleic acid 46 amplicon 46 Spectral Imaging 46 ESI TOF 46 cyto 46 glycosyltransferase 46 Enzyme Linked Immunosorbent Assay 46 insulin resistance HOMA IR 46 AtherOx 46 biomarker validation 46 interactome 46 protein biosynthesis 46 hepatic lipid 46 liquid chromatography tandem 46 immunohistochemistry 46 microarray experiments 46 NPM1 mutation 46 nanostructural 46 tumor excision 46 toxicogenomics 46 potency selectivity 46 RFLP 46 verified experimentally 46 logistic regression 46 transfection 46 nucleolar 46 thyroglobulin 46 subtyping 46 targeted resequencing 46 TSQ Quantum 46 SAXS 46 mutational analysis 46 Pharmacodynamic 46 VeraTag 46 Ascentis Express 46 PCR assays 46 genomic proteomic 46 serum lipid 46 vivo pharmacology 46 Sensitivity Analysis 46 Mathematical modeling 46 Isotopic 46 FFPE tissues 46 SLNB 46 PET CT colonography 46 lymph node metastasis 46 inferential statistics 46 insertional mutagenesis 46 Affymetrix GeneChip 46 tonometry 46 microRNA biomarkers 46 ZFN 46 array comparative genomic 46 BACcel ™ 46 astatine 46 Prognostic factors 46 linear extrapolation 46 preoperative staging 46 residual confounding 46 transcriptome profiling 46 scatterometry 46 explanatory variables 46 Dynabeads 46 enzyme immunoassay EIA 46 foil resistor 46 adrenocortical 46 FT IR spectroscopy 46 somatostatin receptor 46 nonvascular 46 RT PCR assay 46 Pearson correlation coefficients 46 equimolar 46 LDL HDL 46 microsomal 46 gene expression profiling 46 metastatic lymph nodes 46 HeliScope Sequencer 46 TMEM 45 Electrophoresis 45 transduction 45 zeta potential 45 diagnostic prognostic 45 nucleotide substitutions 45 kinase profiling 45 Elastography 45 immunocytochemistry 45 T SPOT.TB 45 Tissue Doppler 45 CT angiography CTA 45 Genetic variation 45 equilibration 45 scintigraphic 45 probabilistic 45 lability 45 DNA amplification 45 immunostaining 45 linkage disequilibrium LD 45 pulsed Doppler 45 bivariate 45 plasma proteome 45 chromatin immunoprecipitation ChIP 45 chi squared 45 prognostic significance 45 EM simulation 45 Single Photon Emission Computed 45 CSF biomarkers 45 p# INK4a 45 thyroid carcinoma 45 CD# expression [001] 45 histopathologic 45 bioassay 45 clinicopathological 45 TRUS 45 MALDI TOF 45 pathologic examination 45 rheological 45 MALDI 45 diagnostic assays 45 velocimetry 45 viral tropism 45 RNA seq 45 ELISPOT 45 SELDI TOF MS 45 prognostic biomarker 45 karyotyping 45 Supplementary Table 45 colonography 45 Fourier domain 45 ventilation perfusion 45 ZFN mediated 45 intact parathyroid hormone 45 electroencephalographic 45 multi analyte 45 photostability 45 multimodality imaging 45 cosmological parameters 45 histopathology 45 tissue oxygenation 45 pharmacodynamic markers 45 HPLC MS 45 electrophysiologic 45 stochastic simulation 45 glycaemia 45 quantitatively assess 45 hyperspectral imagery 45 splice variant 45 elucidation 45 calibration 45 gadolinium enhanced 45 hyperinsulinemic euglycemic clamp 45 NIST traceable 45 oligonucleotide ligation 45 Fourier transform 45 κ 45 confocal microscopy 45 RNA synthesis 45 preimplantation 45 CT angiograms 45 gene expression assays 45 solubilizing 45 diffusion coefficients 45 laser capture microdissection 45 FTIR spectroscopy 45 urine dipstick 45 RNAi mediated 45 FDG PET CT 45 absorbance 45 Predictive modeling 45 physiologically relevant 45 prognostic indicator 45 isotypes 45 Lp PLA 2 45 sorption 45 tissue perfusion 45 bronchoscopic 45 ionization mass spectrometry 45 Genotypic 45 mechanistic explanation 45 miRNA expression 45 mass spectrometry GC 45 pT3 45 Sanger Sequencing 45 analysis 45 isotope ratio 45 subsurface imaging 45 uncharacterized 45 proteins nucleic acids 45 mechanistic insights 45 multigenic 45 LC MS MS 45 vibrational spectroscopy 45 immunofluorescence 45 p# antigen 45 coexpression 45 biomarker discovery validation 45 VE cadherin 45 vivo potency 45 Eq. 45 probe amplification MLPA 45 FRAP 45 gene loci 45 chromatographic separations 45 Trofex 45 protein conformation 45 emulsion PCR 45 functionalization 45 indications contraindications 45 mechanistic studies 45 optical spectroscopy 45 validation 45 DNA Methylation 45 titrations 45 posttranslational modification 45 binding affinities 45 Descriptive statistics 45 biospecimen 45 spectroscopists 45 optimization algorithms 45 vivo molecular imaging 45 UV Visible 45 enzymes immunodiagnostics 45 genome annotation 45 assign probabilities 45 macrophage infiltration 45 Finite element 45 Microarray analysis 45 ascertainment 45 linearized 45 Histopathologic 45 nucleic acid extraction 45 5 hmC 45 DSM IV diagnoses 45 optimization 45 antibody arrays 45 chest radiography 45 PCR primers 45 TOF MS 45 morphologic characteristics 45 vitro molecular diagnostic 45 picogram 45 methylation profiling 45 Polymerase Chain Reaction PCR 45 antimicrobial susceptibility testing 45 carcinoembryonic antigen 45 Transcriptome 45 viral kinetics 45 aetiology 45 Tr DNA 45 absorption spectroscopy 45 mass spectrometry 45 biomarker assay 45 Raman microscopy 45 catalyzed reactions 45 binary logistic regression 45 biochemical marker 45 spectroscopic techniques 45 proteomic biomarkers 45 Aspergillus nidulans 45 generalized estimating 45 Histological 45 2D gel 45 Multivariate analysis revealed 45 anatomical landmarks 45 enhanced sonography 45 genes differentially expressed 45 sonographic 45 CEACAM1 45 anti JCV antibody 45 Noninvasive 45 microRNA expression 45 unmixing 45 triacylglycerols 45 serum biomarker 45 pathogenetic 45 NMR spectra 45 optimality 45 Prostate Cancer Progression 45 ChemoFx ® 45 mTOR inhibition 45 Methylation 45 NPRL2 45 Confirmatory 45 linear regression analysis 45 N glycan 45 proteolytic 45 VEGF expression 45 ProMIS TM 44 enzymatic assay 44 Fourier Transform 44 protein tyrosine phosphatase 44 genomic epigenomic 44 Neanderthal genome sequence 44 Bonferroni correction 44 de novo sequencing 44 Synapt HDMS 44 exome sequencing 44 BACcel ™ system 44 Haplotype 44 lesional 44 nitrite nitrate 44 Quantifying 44 P cadherin 44 parameter estimation 44 chemisorption 44 ClinProt 44 gene rearrangement 44 human proteome 44 sphericity 44 Secondary efficacy endpoints 44 methylation markers 44 absorption spectra 44 ChIP 44 S nitrosylation 44 colorimetry 44 ADME Tox 44 selectively inhibiting 44 proviral 44 sestamibi 44 radioimmunoassay 44 MR spectroscopy 44 pulmonary nodules 44 co receptor tropism 44 Analyte 44 macromolecular 44 serum lactate 44 cytological 44 RNA polymerases 44 modulated signals 44 ELISA enzyme 44 refractive correction 44 backscattering 44 stratify patients 44 apparent diffusion coefficient 44 clinico pathological 44 epistasis 44 prostanoid 44 LTQ Orbitrap Velos 44 cDNA sequencing 44 polymorphs 44 Stimulated Emission 44 Neuropsychiatric Inventory NPI 44 Schematic illustration 44 physicochemical properties 44 affinity purification 44 measurements 44 Multivariate logistic regression 44 induced phosphorylation 44 SYBR Green 44 hierarchical clustering 44 interstitial fluid 44 metaanalysis 44 biophotonic 44 isotope fractionation 44 DCE MRI 44 hormone receptor status 44 convergent validity 44 fluorimetric 44 glutamic acid decarboxylase 44 Transferrin 44 morphometrics 44 risk stratification 44 vitro assay 44 #T# L1 44 Molecular biology 44 microdissection 44 linkage disequilibrium 44 PathFinderTG 44 metabolic parameters 44 Pearson correlation coefficient 44 Guava EasyCyte 44 HRCT 44 DHPLC 44 DFT calculations 44 urodynamic parameters 44 tSMS 44 ratiometric 44 SDS PAGE 44 Raman spectroscopic 44 modulation 44 ARPES 44 multivariable Cox 44 densitometry 44 bFGF 44 LightLab OCT 44 steroidogenic 44 electromechanical coupling 44 nonionic 44 radiographic findings 44 chemoprevention trials 44 Masimo SpHb 44 nucleotide sequences 44 myocardial perfusion 44 pathophysiological 44 non dispersive infrared 44 developmental neurotoxicity 44 cell lysate 44 virulence genes 44 cDNA clone 44 microbiologic 44 Reflectance 44 DIGE 44 PD2i R 44 KRAS variant 44 squamous intraepithelial lesions 44 ultrasensitive detection 44 FFPE 44 spectroscopic methods 44 stereochemical 44 photoionization 44 combinatorial libraries 44 PSA kinetics 44 chromatogram 44 intracellular pH 44 MDCTA 44 ELISA kit 44 fig. S8 44 gene annotation 44 Coulomb blockade 44 magnon 44 spectroscopic analysis 44 sequencing 44 statistical correlations 44 biomolecule 44 endorectal coil 44 SELDI 44 ICP OES 44 Troponin T 44 TPMT 44 enzyme inhibition 44 CO2 CH4 44 proteomics 44 conventional atomic absorption 44 ImmuKnow 44 Cockcroft Gault 44 spatiotemporal 44 quantization 44 causative mutations 44 detecting coronary artery 44 tissue microarray 44 cytotoxicity 44 verification MRV 44 logistic regressions 44 biochemical markers 44 polygenic 44 bovine genome 44 #m Tc 44 differentially expressed genes 44 endosomal 44 X ray Fluorescence 44 xCELLigence 44 cCTA 44 radiolabeled 44 computed tomography SPECT 44 bioimaging 44 MS DRG 44 quantitive 44 homology modeling 44 KineMarker TM 44 PQA# 44 solubilization 44 epitope mapping 44 metabolic profiling 44 kinase inhibition 44 MTT assay 44 differentiate squamous 44 denaturing gradient gel electrophoresis 44 completeness correctness 44 mass spectrometry MS 44 interindividual variability 44 minimization 44 spectral Doppler 44 2D electrophoresis 44 photothermal 44 differential diagnosis 44 prion infection 44 methemoglobin SpMet 44 UPLC MS 44 diagnosing coronary artery 44 aggregometry 44 methylated DNA 44 chemoinformatics 44 CORE OM 44 myocardial function 44 delipidation 44 Radical prostatectomy 44 Capillary Electrophoresis 44 reagent kit 44 FRET 44 biotransformation 44 biomarker profiling 44 microCT 44 immunofluorescence microscopy 44 intercellular signaling 44 nonlinearities 44 4D imaging 44 spectroscopically 44 QSAR 44 plasma pharmacokinetics 44 logistic regression analysis 44 SELDI TOF 44 TURBT 44 NMR spectroscopy 44 multigene 44 Rosetta Elucidator 44 glycolytic 44 Amino acid 44 finite element modeling 44 nodal metastasis 44 Signaling Analyzer 44 TDOA 44 parasitological 44 nuclide 44 replicase 44 FDG uptake 44 pharmacodynamic biomarkers 44 Cathepsin B 44 heterozygosity LOH 44 stoichiometry 44 SensoLyte ® 44 η 44 bioanalysis 44 bioluminescence imaging 44 TLE3 44 enzymatic conversion 44 alkaline phosphatase ALP 44 VeraCode 44 serum thyroglobulin 44 ultrahigh resolution 44 BACcel 44 HIV tropism 44 inorganic compounds 44 spatial variability 44 lymphovascular invasion 44 biopsied tissue 44 central corneal thickness 44 resected tissue 44 molecular diagnostic assays 44 VeraTag assays 44 ligand induced 44 kallikrein 44 Topoisomerase II 44 Fig. 2B 44 HER2 HER3 44 HIV1 44 biological macromolecules 44 beta. 44 bioluminescent imaging 44 sequence homology 44 Virological 44 fig. S7 44 constitutively expressed 44 myocardial infarct size 44 oligomer 44 lymphatic mapping 44 Flt3 44 metagenomic sequencing 44 TNM staging 44 nanoliter scale 44 ANOVA 44 VerifyNow P#Y# 44 alpha emitting 44 rumen fermentation 44 heterotrophic 44 beta1 integrin 44 cytotoxicity assays 44 noninvasive imaging 44 neuritic 44 NGAL 44 peginterferon alpha 44 enthalpy 44 nosology 44 detrusor 44 LC MS 44 asymptotic 44 confocal laser scanning 44 parasitaemia 44 eNO 44 liver metastasis 44 immunomagnetic 44 tractography 44 prognostic biomarkers 44 DNMT1 44 reagent 44 multidetector row 44 Genedata Expressionist 44 ultrastructure 44 statistical significance p 44 gravitational redshift 44 paraffin embedded tissue 44 transfer FRET 44 Anticalin ® 44 aggregative 44 fluorination 44 spectroscopic 44 oligonucleotide microarray 44 envelope glycoprotein 44 mycobacterial 44 situ hybridisation 44 adsorption isotherms 43 Extracellular 43 EQ 5D 43 needle aspiration 43 MALDI TOF MS 43 heparanase 43 leachables 43 fluorescence microscopes 43 circulating endothelial cells 43 imaging mass spectrometry 43 N acetyl 43 Mendelian randomization 43 chronicity 43 impedance measurement