Related by context. All words. (Click for frequent words.) 79 reactive oxygen species ROS 74 superoxide 69 antioxidant enzyme 68 oxidative stress 68 reactive oxygen 68 NADPH oxidase 68 proteases 68 inflammatory cytokines 68 oxidants 67 peroxynitrite 67 prostaglandin E2 66 lipid peroxidation 66 hydroxyl radical 66 catalase 66 IL 1beta 66 hydroxyl radicals 65 cytokine 65 cytokines 65 oxidative 65 polyamines 65 cyclic AMP 65 progranulin 65 superoxide radicals 65 lipid peroxides 65 eicosanoids 65 proinflammatory cytokines 65 Oxidative stress 64 cytochrome c 64 pro inflammatory cytokines 64 IL 1β 64 NAD + 64 microglial cells 64 Wnt signaling 64 sortilin 64 protein kinase C 64 caveolin 1 64 eNOS 63 Aß 63 mitochondria 63 hematopoietic cells 63 Aβ 63 phagocytes 63 inflammatory mediators 63 excitotoxic 63 PGE2 63 anti apoptotic 63 Skp2 63 intracellular calcium 63 Treg cells 63 TNFa 63 nitric oxide synthase 63 suppressor cells 63 ceramide 63 neurotrophins 63 FGF# 63 TGF beta 63 cAMP 63 oxidative damage 63 iNOS 63 MAP kinase 63 glutamate 62 inflammatory cytokine 62 proteolysis 62 myeloid cells 62 ABCA1 62 GLI1 62 beta catenin 62 TGF ß1 62 phagocytosis 62 Reactive oxygen species 62 ERK1 2 62 reactive molecules 62 IL #p# 62 oncoprotein 62 glutathione 62 SGK1 62 TSLP 62 TGF β 62 alpha synuclein 62 endothelial nitric oxide 62 Th2 cells 62 amyloid β 62 fatty acid oxidation 62 mutant protein 62 cardiac fibroblasts 62 arachidonic acid 62 HSF1 62 frataxin 62 cofilin 62 plasminogen 62 senescent cells 62 matrix metalloproteinases 62 antioxidant enzymes 62 prostaglandin E2 PGE2 62 chitinase 62 NKT cells 62 amyloid protein 62 microglial activation 62 microglia 62 p# protein 62 stromal cells 62 myeloid derived 62 endothelial nitric oxide synthase 62 RANKL 62 HbF 61 leukotrienes 61 Abeta# 61 eosinophils 61 apoptotic 61 intracellular 61 catecholamine 61 LDL receptor 61 CYP#B# 61 β catenin 61 caspase activation 61 glutamate receptors 61 β amyloid 61 activin 61 anti inflammatory cytokines 61 catenin 61 Abeta 61 proinflammatory 61 singlet oxygen 61 Clusterin 61 MDM2 61 Mcl 1 61 IL 1ß 61 heme oxygenase 61 NF κB 61 upregulation 61 prostaglandins 61 vascular endothelial cells 61 tau protein 61 autoantibodies 61 β cells 61 cardiac myocytes 61 TNF α 61 lipofuscin 61 STAT3 61 c MYC 61 mitochondrial biogenesis 61 mitogen activated protein kinase 61 ACh 61 miR# 61 CLL cells 61 transcriptional activation 61 induced neuronal 61 clusterin 61 amyloid peptide 61 osteoblast 61 autophagic 61 superoxides 61 TSP1 61 PPAR gamma 61 bile acid 61 nitric oxide NO 61 PIP3 61 platelet activation 61 interleukins 61 SIRT1 61 retinoic acid 61 osteoclasts 61 mitochondrial function 61 prostaglandin synthesis 61 oxidative stress inflammation 61 nitrotyrosine 61 thioredoxin 61 excitatory neurotransmitter glutamate 61 TGF beta1 61 goblet cells 61 extracellular calcium 61 NF kB 61 astrocytes 60 thyroid hormone 60 catabolism 60 mutant proteins 60 arginase 60 p#NTR 60 overexpression 60 MDSCs 60 anti inflammatory cytokine 60 mutated protein 60 Hedgehog pathway 60 endoplasmic reticulum stress 60 signaling pathway 60 paxillin 60 IFNg 60 angiotensin II 60 Alu RNA 60 estrogen receptor alpha 60 Nitric oxide NO 60 thyrotropin 60 neural cells 60 amyloid beta 60 mitochondrial fusion 60 neuronal cell 60 allergic inflammation 60 p# activation 60 lysosomal 60 toxic beta amyloid 60 Runx2 60 genomic instability 60 microglial 60 aldosterone 60 elastase 60 mitochondrial 60 cyclin D1 60 oxidized LDL 60 mitogen 60 toxic amyloid beta 60 reactive oxygen molecules 60 glycolipids 60 glioma cells 60 pro inflammatory cytokine 60 E cadherin 60 Smad3 60 androgens 60 keratinocytes 60 TGFb 60 enzyme aromatase 60 Rab5 60 huntingtin 60 porphyrins 60 Th# cells 60 EZH2 60 cathepsins 60 oxidative phosphorylation 60 Akt 60 Nrf2 60 ARF1 60 intestinal epithelial cells 60 erythrocytes 60 ENaC 60 angiotensinogen 60 interferon gamma 60 adrenal cortex 60 melanocyte 60 mesenchymal cells 60 Hsp# [001] 60 Ca2 + 60 SIRT3 60 calcineurin 60 apoptosis 60 neuronal dysfunction 60 metabolic enzymes 60 constitutively 60 amyloid beta peptides 60 osteocalcin 60 Oxidative stress occurs 60 PI3K pathway 60 neurite outgrowth 60 MMPs 60 androgen receptors 60 enzymatic activity 60 endogenous 60 TGF b 60 LTB4 59 aberrantly activated 59 adipocyte 59 ectopic expression 59 Wnt pathway 59 cytokine IL 59 Th2 59 heme oxygenase 1 59 tumor suppressor proteins 59 signaling cascades 59 synuclein 59 peroxidation 59 oncogenic 59 osteopontin 59 NFkB 59 IGF 1R 59 Rap1 59 mitochondrial dysfunction 59 protein synthesis 59 adipokines 59 vascular permeability 59 TAp# 59 systemic inflammation 59 TGF ß 59 mammary cells 59 nitric oxide 59 intestinal epithelium 59 superoxide dismutase 59 glial cells 59 protein alpha synuclein 59 enzyme 59 tumor cells 59 Hedgehog signaling 59 steroid hormones 59 bile acids 59 protein beta amyloid 59 GRK2 59 leukocytes 59 TGF alpha 59 MMP9 59 peripheral tissues 59 metalloproteinases 59 tumor suppressor protein 59 regulated kinase ERK 59 NADH 59 myofibroblast 59 PHD2 59 hormone aldosterone 59 IFN gamma 59 species ROS 59 HDAC6 59 keratinocyte 59 protein CETP 59 hedgehog pathway 59 mammalian cells 59 SETDB1 59 beta adrenergic receptors 59 intracellular pathways 59 apoptotic cells 59 HPA axis 59 SIRT1 gene 59 renal fibrosis 59 Wnt 59 hepatic glucose production 59 androgen receptor 59 thyroid hormones 59 malonyl CoA 59 podocytes 59 4E BP1 59 secretory pathway 59 acrolein 59 Myc 59 GPx 59 ketone bodies 59 receptor gamma 59 TXNIP 59 selective inhibition 59 autophagy 59 HSP# 59 caspases 59 beta catenin protein 59 pro apoptotic 59 cellular metabolism 59 amyloid beta plaques 59 excess glutamate 59 TMEM#B 59 TGF beta pathway 59 neurofibrillary tangles 59 glioblastoma cells 59 S#A# [002] 59 neurotrophic factors 59 SIRT6 59 p# MAPK 59 N Myc 59 cytokines proteins 59 fibroblasts 59 enterolactone 59 aromatase 59 induce apoptosis 59 mutant huntingtin protein 59 macrophages 59 amyloid beta protein 59 pRb 59 p# pathway 59 proteins 59 diffusible 59 insulin receptors 59 PrPC 59 micro RNAs 59 fibrocytes 59 alpha synuclein protein 59 hyperactivation 59 Tregs 59 proto oncogene 59 T lymphocytes 59 miR #a [002] 59 HIF 1alpha 59 EphB2 59 OGG1 59 dephosphorylation 59 endothelial progenitor cells 59 CCL# 59 intracellularly 59 amyloid ß 59 bacterial toxins 59 procaspase 3 59 SIRT2 59 synaptogenesis 59 B lymphocytes 59 granulocytes 59 S1P 59 UCP1 59 superoxide dismutase SOD catalase 59 CD8 T cells 59 PEDF 59 NF kappaB 59 EphA2 59 cofactor 59 UCP2 58 paracrine 58 CTGF 58 amyloid beta peptide 58 thyroxine T4 58 overactivation 58 primary cilia 58 selenoproteins 58 TNFalpha 58 deacetylation 58 galanin 58 amyloid proteins 58 collagen synthesis 58 adipogenesis 58 neuroblastoma cells 58 secreted protein 58 CXCL# 58 signaling molecule 58 BMP signaling 58 NF kappaB activation 58 Cyclin D1 58 asparagine 58 glucose uptake 58 amyloid fibrils 58 lipids 58 mutant huntingtin 58 cyclooxygenase 58 adiponectin 58 overexpressing 58 RBP4 58 inducible nitric oxide synthase 58 eukaryotic cells 58 cPLA2 58 glutathione GSH 58 neuronal cells 58 LDL receptors 58 Leukotrienes 58 glucocorticoid receptor 58 adiponectin hormone 58 NFκB 58 inhibitory effect 58 pancreatic islet 58 endocannabinoids 58 androgen receptor AR 58 excitotoxicity 58 excess TNF alpha 58 glycation 58 genotoxic stress 58 sFlt 1 58 superoxide anion 58 extracellular 58 Akt1 58 Kupffer cells 58 Cdc# 58 prostate tissue 58 peroxisomes 58 oxidant stress 58 beta amyloid peptide 58 quinone 58 CD1d 58 tumor suppressor genes 58 PrP 58 oxidized lipids 58 fibrin deposition 58 tumorigenesis 58 5 lipoxygenase 58 Aβ# 58 TNF alpha 58 AhR 58 polyamine 58 TORC2 58 basophils 58 EGF receptor 58 apoptotic pathway 58 PAK1 58 fibrogenesis 58 GRP# 58 c myc 58 ERK2 58 neuronal differentiation 58 MT1 MMP 58 osteoclast activity 58 immune cells 58 neutrophils 58 MAPK 58 NPD1 58 innate immune 58 NKG2D 58 erythropoiesis 58 autoantibody 58 VE cadherin 58 GAPDH 58 Overexpression 58 apoE 58 ferroportin 58 palmitoleate 58 leukemic cells 58 PPAR γ 58 NMDA receptors 58 COX enzymes 58 nitric oxide synthase NOS 58 hormone cortisol 58 beta amyloid protein 58 neutrophil 58 spermidine 58 hepcidin 58 oxidant 58 TLR4 58 Foxp3 58 signaling molecules 58 Adiponectin 58 adrenal hormones 58 Sirt3 58 reductase 58 amyloid peptides 58 S#K# 58 superoxide dismutase SOD 58 cyclin E 58 LRP6 58 ß amyloid 58 hypoxia inducible factor 58 cytosolic 58 HIF 1α 58 intracellular proteins 58 58 ubiquitination 58 mediating pathological inflammation 58 isothiocyanates 58 amyloid deposits 58 myofibroblasts 58 androgen 58 metalloproteases 58 Drp1 58 dopamine neurons 58 Notch signaling 58 Wnts 58 VEGF receptor 58 lymphocytes 58 oxidative DNA 58 leptin signaling 58 serine protease 58 endocrine glands 58 neuropeptide Y 58 apoptosis programmed cell 58 macrophage 58 ouabain 58 SCD1 58 pro angiogenic 58 SOD1 58 T lymphocyte 58 Neu5Gc 58 tyrosine phosphorylation 58 melanocyte stimulating hormone 58 lymphocyte activation 58 tryptase 57 fetal hemoglobin 57 eicosanoid 57 PKM2 57 sebaceous glands 57 cyclic AMP cAMP 57 diseased tissues 57 astrocyte 57 sphingolipid 57 c MET 57 oxidases 57 estrone 57 NFAT 57 focal adhesions 57 androgen hormones 57 pro apoptotic proteins 57 JAK2 enzyme 57 ptau 57 SMN protein 57 LNCaP cells 57 auxin 57 heme 57 amyloid deposition 57 adipocytes 57 Pin1 57 dihydrotestosterone DHT 57 thromboxane 57 p# MAP kinase 57 Wnt signaling pathway 57 skeletal muscle cells 57 myo inositol 57 proteolytic enzymes 57 cyclins 57 focal adhesion kinase FAK 57 molecular signaling pathway 57 acetyl CoA 57 effector T 57 glial 57 mTORC1 57 adipogenic 57 lysosomal enzyme 57 calpain 57 MAPK pathway 57 enzymes 57 Fas ligand 57 vimentin 57 dopaminergic neurons 57 palytoxin 57 F actin 57 FGFR3 57 FGFR1 57 neurogenesis 57 BCL2 57 GluR1 57 HER2 protein 57 oncoproteins 57 cathelicidin 57 Hypoxia Inducible Factor 57 adipose cells 57 autoantibodies antibodies 57 micronuclei 57 chromosomal instability 57 estrogen hormone 57 tau phosphorylation 57 EETs 57 cyclic GMP 57 redox active 57 proinflammatory cytokine 57 histone deacetylases 57 lysosome 57 NF KappaB 57 upregulated 57 effector cells 57 transgene expression 57 presynaptic 57 druggable target 57 LKB1 57 proton pump 57 super oxide dismutase 57 inhibitory 57 activated microglia 57 anti apoptotic proteins 57 morphogen 57 effector functions 57 TGF β1 57 PDGFR 57 CCL5 57 downregulated 57 p# alpha [001] 57 Myc protein 57 brain derived neurotrophic 57 Notch1 57 Cdc7 57 acinar 57 neuritic plaques 57 HDL particles 57 activated lymphocytes 57 calcium homeostasis 57 normal prion proteins 57 hydrolases 57 metabolic processes 57 PGC1 57 fatty acid synthesis 57 TGFβ 57 mRNA expression 57 atherogenesis 57 FOXO1 57 carcinogenic compounds 57 induces apoptosis 57 mitochondrial enzyme 57 tau proteins 57 nicotinamide 57 cyclic adenosine monophosphate cAMP 57 adenylate cyclase 57 ferulic acid 57 apoptotic cell 57 G6PD 57 p#Kip# 57 metal ions 57 gamma aminobutyric acid GABA 57 lymphoid cells 57 oxysterols 57 STAT1 57 ovarian hormones 57 ATPase 57 glial cell 57 E#F# 57 receptor signaling 57 factor PlGF 57 PTPN# 57 coenzyme 57 neurotrophic 57 MMP2 57 TGFbeta 57 melanin pigments 57 secretase 57 cyclooxygenase 2 57 MAPKs 57 insulin secreting cells 57 carbohydrate metabolism 57 oxidase 57 ER alpha 57 neurofibromin 57 HER2 receptors 57 mRNA molecules 57 myeloma cells 57 Src kinase 57 nerve cells 57 HDAC2 57 cell adhesion molecule 57 HuR 57 RAR beta 57 neurodegeneration 57 endocytosis 57 RhoA 57 adrenocortical 57 pancreatic cells 57 menin 57 mesothelin 57 XBP1 57 Stat1 57 cathepsin B 57 BACE1 57 protective antioxidant enzymes 57 CatB 57 VEGF 57 monocyte 57 granzyme B 57 cell signaling pathway 57 insulin secretion 57 bcl 2 57 osteoblasts 57 BDNF 57 homodimers 57 RANK ligand 57 gene p# 57 somatostatin 57 Aldosterone 57 glomerular 57 neuropeptide Y NPY 57 cytokine signaling 57 amyloid plaque 57 mitochondrial mutations 57 intracellular accumulation 57 FasL 57 CCN2 57 radical scavenging 57 innate immune responses 57 catecholamines 57 intracellular signaling 57 FANCD2 57 ubiquitylation 57 POMC neurons 57 hematopoietic 57 cardiolipin 57 ERK signaling 57 normal prion protein 57 TORC1 57 pDCs 57 inorganic mercury 56 gluconeogenesis 56 uric acid 56 beta subunit 56 B7 H1 56 gut mucosa 56 stress hormone corticosterone 56 axonal 56 cell lysis 56 NADPH 56 VSMC 56 eotaxin 56 neurotransmitter glutamate 56 p# mutations 56 monocytes 56 proteoglycan 56 phosphatases 56 telomere dysfunction 56 neuronal 56 Th1 cells 56 uPAR 56 hydroperoxide 56 amyloid beta proteins 56 VEGF expression 56 cholesterol metabolism 56 enzyme cytochrome 56 lipoxygenase 56 synovial cells 56 endogenous ligands 56 PPARg 56 haematopoietic stem cells 56 oligodendrocytes 56 lactate dehydrogenase 56 thromboxane A2 56 myeloperoxidase 56 gamma secretase 56 neuronal function 56 TRAF6 56 NFATc1 56 nestin 56 GABAergic interneurons 56 innate immune response 56 hedgehog signaling 56 agonist induced 56 chloroplasts 56 tumor microenvironment 56 NRF2 56 beta amyloid peptides 56 atherosclerotic plaques 56 nitrosamines 56 IGF2 56 phagocyte 56 dopaminergic cells 56 fibrotic 56 mutant p# 56 bone resorption 56 sebum 56 ERK pathway 56 cytotoxicity 56 glucocorticoid 56 proapoptotic 56 cellular senescence 56 WT1 56 induced apoptosis 56 oncogenic transformation 56 transgenic mice expressing 56 breast epithelial cells 56 aldose reductase 56 lipopolysaccharide 56 Prolactin 56 abscisic acid 56 glycosylation 56 matriptase 56 MAP kinases 56 spermatogenesis 56 phosphorylates 56 NK cells 56 fatty acid synthase 56 Bcl xL 56 inhibitory effects 56 angiogenic 56 apoptotic pathways 56 cell signaling pathways 56 AMPA receptors 56 RUNX3 56 TTR gene 56 Wnt proteins 56 Th1 type 56 Pten 56 bone morphogenetic proteins 56 hair follicle stem cells 56 hsp# 56 γ secretase 56 ubiquinol 56 CD#L 56 CaM kinase 56 von Willebrand factor 56 c Myc 56 LRP5 56 melanocytes 56 estrogen metabolism 56 IL6 56 endoxifen 56 cyclic adenosine monophosphate 56 FOXM1 56 neuroinflammation 56 ß catenin 56 cellular organelles 56 mRNAs 56 EGFR signaling 56 synapse formation 56 TET2 56 bacterial enzymes 56 Akt signaling 56 MEK ERK 56 podocyte 56 serotonin receptor 56 histone acetylation 56 factor GDNF 56 ATPase activity 56 nodulation 56 phosphatidylinositol 3 56 mutagens 56 neurotransmitter 56 epithelial tissues 56 misfolded proteins 56 FGFs 56 glutathione peroxidase 56 urinary excretion 56 proNGF 56 serotonin synthesis 56 serine proteases 56 macrophage cells 56 alpha Gal 56 Htt 56 Aâ 56 epithelia 56 protein tau 56 tyrosine kinases 56 acyl CoA 56 oxidative enzymes 56 PP2A 56 IRAK1 56 dimerization 56 nAChRs 56 MEF2D 56 oncomodulin 56 Sirt1 56 Klotho 56 neurotransmitter acetylcholine 56 haematopoietic 56 noradrenaline 56 uPA 56 GH secretion 56 proteoglycans 56 MnSOD 56 transcriptional repressor 56 Th# 56 interleukin 1β 56 Id1 56 endothelial 56 lymphotoxin 56 receptor protein 56 caveolin 56 adipokine 56 exocytosis 56 cell motility 56 FOXO3a 56 chondrocytes 56 proteasomes 56 GPR# [002] 56 neurotransmitter dopamine 56 extracellular signal 56 naturally occurring enzymes 56 microtubule dynamics 56 vasoconstriction 56 peroxisome 56 cysteine 56 BCL#A 56 protein kinases 56 Hh pathway 56 protein fragment 56 oncogenes 56 lipoprotein lipase 56 motor neurons 56 synaptic vesicles 56 cystine 56 glutamine 56 estrogen receptor 56 malignant transformation 56 pigment melanin 56 trophoblast cells 56 beta amyloid 56 plasmin 56 IKKß 56 Osteoclasts 56 amyloid 56 mRNA 56 neurons 56 myogenesis 56 oligomers 56 acetylcholine 56 estrogen receptors 56 Fc receptors 56 NFkappaB 56 PTH secretion 56 vasodilatory 56 copper zinc superoxide 56 thymic 56 PAR1 56 Purkinje cells 56 hypothalamic pituitary 56 naturally occurring enzyme 56 GSK3 56 receptor subtype 56 mitochondrial membrane potential 56 lysosomes 56 endogenous cannabinoids 56 fatty molecules 56 PKC isoforms 56 intestinal epithelial 56 microvascular endothelial cells 56 cyclic nucleotides 56 TH# cells 56 tumor suppressor 56 apoC III 56 MMP7 56 collagen VI 56 huntingtin protein 56 germ cells 56 antimicrobial peptides 56 E3 ligase 56 activate p# 56 neurotransmission 56 Src 56 dystroglycan 56 KLF2 56 inhibiting tumor 56 ADAM# 56 ferritin 56 RAS RAF MEK 56 glucocerebroside primarily 56 antitumor 56 mitochondrial respiration 56 cytolytic 56 vascular endothelial 56 MAPCs 56 phosphorylation 56 RIP1 56 BRAF gene 56 DNMT1 56 radical scavenger