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(Click for frequent words.) 72 selective inhibition 71 potent inhibitors 71 small molecule inhibitors 71 selective inhibitor 70 selectively inhibit 70 proteasome inhibitors 69 selective antagonists 69 histone deacetylase inhibitors 69 peroxisome proliferator activated 69 CCR2 69 PPARγ 69 phosphate S1P 68 HDACs 68 Hsp# inhibitors 68 VEGF receptor 68 kinase inhibitors 68 enzyme inhibitors 68 GSK3B 68 orally bioavailable 68 reversible inhibitor 68 HDAC inhibitors 68 induce apoptosis 68 cyclooxygenase 68 selectively inhibits 67 cytoprotective 67 glucocorticoid receptors 67 p# inhibitors 67 P#X# 67 MEK inhibitors 67 selective antagonist 67 Preclinical studies suggest 67 FGFR 67 potent inhibitor 67 cyclin dependent kinase inhibitor 67 poly ADP ribose polymerase 67 antagomirs 67 PI3 kinase 67 EGF receptor 67 receptor tyrosine kinase inhibitor 67 cyclins 67 small molecule inhibitor 67 humanized monoclonal antibodies 67 5 lipoxygenase 66 oral prodrug 66 enzyme inhibitor 66 Epidermal Growth Factor Receptor 66 mTOR inhibitors 66 SERMs 66 selective modulator 66 histone deacetylase inhibitor 66 pan HDAC inhibitor 66 SARMs 66 HSP# inhibitor 66 anticancer agents 66 cyclin dependent kinases 66 sodium glucose cotransporter 66 VEGF inhibitors 66 uPAR 66 small molecule activators 66 histone deacetylase 66 PI3K inhibitor 66 protein kinase C 66 receptor subtypes 66 FGFR2 66 receptor antagonists 66 epothilone 66 proteasome inhibitor 66 neuroprotective properties 66 enkephalin 66 TNFa 66 humanized antibody 66 BMS # 66 tyrosine kinase inhibitor 66 5 HT4 receptor 65 5alpha reductase 65 IAP inhibitor 65 partial agonist 65 FLT3 65 Upregulation 65 splice variants 65 CDK inhibitor 65 vascular disrupting agents 65 erlotinib Tarceva ® 65 inhibitory effects 65 receptor PPAR 65 retinoic acid receptor 65 CDKs 65 CYT# potent vascular disrupting 65 ENMD # 65 investigational humanized monoclonal antibody 65 immunomodulatory 65 JAK3 65 diagnostic biomarker 65 novel peptide 65 nucleoside analogues 65 predictive biomarkers 65 Factor Receptor 65 highly selective inhibitor 65 selective kinase inhibitor 65 anticancer therapies 65 CD# monoclonal antibody 65 phosphatases 65 #ME# 65 inhibitors 65 cyclooxygenase 2 65 anti fibrotic 65 antitumor 65 MTP inhibitor 65 histone deacetylases 65 somatostatin 65 PTP 1B 65 chemopreventive agent 65 SIRT2 65 protein kinase inhibitor 65 mitogen activated protein kinase 65 anti mitotic 65 receptor agonists 65 phosphatidylinositol 3 65 interleukins 65 receptor blocker 65 CORT # 65 gamma secretase inhibitor 65 histone deacetylase HDAC inhibitors 65 IGF IR 65 NS#/#A protease 65 orally administered inhibitor 65 HDAC 65 mGluR4 65 JAK1 64 factor receptor FGFR 64 protein tyrosine phosphatase 1B 64 transient receptor 64 insulin sensitizers 64 sphingosine 1 64 PARP inhibitors 64 estrogen receptor beta 64 microRNA miR 64 vivo validation 64 #HT#A 64 Hedgehog pathway 64 S1P 64 BCR ABL 64 hypoxia inducible factor 64 IAP inhibitors 64 Smac mimetics 64 oncolytic 64 hedgehog pathway 64 PNP inhibitor 64 PPAR alpha 64 Aurora kinase 64 potent anticancer 64 antisense drugs 64 chemokine receptor 64 isoenzymes 64 receptor inhibitor 64 potently inhibit 64 PI3K AKT 64 nucleoside analogs 64 Abl 64 GPCR targets 64 ErbB3 64 Wnt signaling pathway 64 TLR8 64 NS4A 64 AEG# 64 prodrugs 64 K ras mutations 64 antiangiogenic 64 anticancer agent 64 THR beta agonist 64 kinase inhibitor 64 pleiotropic 64 selective agonist 64 PPAR gamma 64 TLR9 64 isoform selective 64 small molecule tyrosine 64 small molecule modulators 64 E#F# 64 receptor modulators 64 CCR1 64 targeting CD# 64 PPARg 64 therapeutic monoclonal antibodies 64 endogenous ligands 64 inhibit viral replication 64 Locked Nucleic Acid LNA 64 MEK inhibitor 64 polyketides 64 HDAC enzymes 64 antisense compounds 64 SGLT2 64 PI3K pathway 64 inhibitor 64 metaglidasen 64 naturally occurring molecule 64 glucocorticoid receptor 64 signaling cascades 64 Protein Kinase C 64 glutamate receptors 64 thrombin receptor 64 histone deacetylase HDAC 64 protein kinases 64 JAK2 inhibitor 64 receptor partial agonist 64 molecularly targeted 64 xenograft models 64 mGlu2 3 63 Curaxins 63 geldanamycin 63 miR #a [002] 63 Epothilones 63 Fibroblast Growth Factor Receptor 63 bexarotene 63 polymerase inhibitor 63 TRV# [001] 63 serotonin receptor 63 gamma secretase inhibitors 63 MMP inhibitors 63 immunomodulating 63 CB2 receptor 63 PGE2 63 pDCs 63 HDACi 63 Nanobody ® 63 5 HT6 receptor 63 Fc fusion protein 63 TTR gene 63 PKC isoforms 63 cyclin E 63 flavopiridol 63 MTHFR 63 iNOS 63 5 HT2A serotonin 63 Chemokine Receptor 63 Cytochrome P# 63 PPARgamma 63 tyrosine kinase inhibitors 63 SGLT2 inhibitors 63 Gleevec resistant 63 inhibitory activity 63 sphingolipid 63 HDAC6 63 synthetic retinoid 63 antitumoral 63 vascular disrupting agent 63 IL 1β 63 serine protease 63 cellular pathways 63 ALK inhibitors 63 ERK1 2 63 GPR# [002] 63 proto oncogene 63 induces apoptosis 63 small molecule agonists 63 HCV protease 63 neuronal nitric oxide synthase 63 Janus Kinase 63 sulindac 63 MEK ERK 63 NFkB 63 cyclin dependent kinase 63 CYP #A# 63 pathophysiological effects 63 potently inhibited 63 oral JAK1 63 potent inhibition 63 DNA intercalator 63 endostatin 63 antiapoptotic 63 cathepsins 63 KLF4 63 VEGF receptors 63 androgen receptor AR 63 p# mitogen activated 63 FGFR1 63 inhibit angiogenesis 63 Hypoxia Inducible Factor 63 cilengitide 63 LDL receptor 63 HDAC inhibition 63 PKCi 63 NKT cells 63 c MET 63 Tyrima 63 Janus kinase 63 eotaxin 63 methyltransferases 63 antitumor effects 63 antiproliferative effects 63 BAY #-# 63 STAT3 63 small molecule activator 63 mGluR2 NAM 63 nicotinic 63 Clusterin 63 AT1R 63 anti proliferative 63 EGFr 63 TGF alpha 63 Dapagliflozin 63 EphA2 63 NS5A 63 PDGF receptor 63 TRAIL receptor 63 ATL# [002] 63 MAPK 63 AKT1 63 IGF 1R 63 ENaC 63 Smurf1 63 HIF 1alpha 63 eNOS 63 immunoregulatory 63 glycosylated 63 kinase pathway 63 calcineurin 63 Squalamine 63 HDAC inhibitor 63 novel VDA molecule 63 inhibit enzymes 63 topoisomerase 63 antisense inhibitors 63 HDAC2 63 oxysterols 62 CBLC# 62 antimitotic 62 ubiquitin ligases 62 cytochrome P 62 5 HT2A inverse 62 NMDA antagonist 62 metalloprotease 62 HMG CoA reductase inhibitors 62 epigenetic therapies 62 metabotropic glutamate receptor 62 Vidaza azacitidine 62 OMP #M# 62 isoforms 62 ERK pathway 62 pharmacokinetic interactions 62 PDGFR 62 anticancer compounds 62 selective orally bioavailable 62 glucagon receptor 62 COX2 62 multi kinase inhibitor 62 vinca alkaloids 62 lapatinib Tykerb 62 delta isoform 62 ALK inhibitor 62 JAK inhibitor 62 investigational monoclonal antibody 62 druggable target 62 immunomodulatory effects 62 epothilones 62 E2F 62 peptide antigens 62 anticancer therapeutics 62 pharmacodynamic biomarkers 62 intracellular protein 62 JAK inhibitors 62 HGS ETR2 62 VEGFR2 62 anti amnesic 62 HepDirect prodrug 62 p# MAPK 62 peripherally acting 62 targeting PCSK9 62 PAR1 62 PI3K Akt 62 immunomodulatory properties 62 micro RNAs 62 kinase inhibition 62 Xanafide 62 c MYC 62 druggable targets 62 act synergistically 62 AKT inhibitor 62 NEUGENE 62 cell adhesion molecule 62 antisense inhibitor 62 vorinostat 62 selective estrogen receptor 62 MDR1 62 Sapacitabine 62 Factor VEGF 62 serine threonine 62 PDE4 inhibitor 62 N methyl 62 ABCB1 62 HER3 62 insulin sensitizer 62 ALN TTR 62 colon carcinoma 62 prostanoid 62 renin inhibitors 62 PI3K/mTOR 62 receptors PPARs 62 γ secretase 62 systemically administered 62 cardioprotective effects 62 immune modulator 62 resolvins 62 KIT mutations 62 inhibitor rofecoxib 62 annexin 62 Notch1 62 brostallicin 62 Deforolimus 62 cortisol receptor 62 cMET 62 PKM2 62 vimentin 62 partial agonists 62 EGFR signaling 62 therapeutic monoclonal antibody 62 humanized monoclonal 62 Aviptadil 62 CCR5 antagonist 62 4E BP1 62 BRAF mutation 62 anticancer drugs 62 TMEM#B 62 Maribavir 62 cytokine receptor 62 adenosine receptor 62 biased ligand 62 prostaglandin E2 62 mda 7 62 matrix metalloproteinases 62 kinase 62 GAP #B# 62 inverse agonist 62 Dasatinib 62 Bucindolol 62 Mipomersen 62 kinases 62 Gleevec inhibits 62 metabolic enzymes 62 imatinib Gleevec 62 liposome encapsulated 62 neurotrophic 62 antisense drug 62 Vidofludimus 62 XmAb# 62 ERBB2 62 vaccine GRNVAC1 62 Symadex 62 EP1 receptor 62 cyclin D1 62 sigma receptors 62 insulin sensitizing 62 bleomycin 62 tubulin polymerization 62 RNAi therapeutic targeting 62 gefitinib Iressa 62 Sphingomab 62 serine threonine kinase 62 Pathway Inhibitor 62 angiotensin 62 Posiphen 62 Glucocorticoids 62 dasatinib Sprycel 62 PPAR γ 62 factor TNF 62 chitinase 62 Smac mimetic 62 chemokine 62 small molecule defensin 62 Valproic acid 62 Aurora kinases 62 COX enzymes 62 anti CD3 62 pyrimidines 62 NF κB 62 siRNAs targeting 62 CYP#A# CYP#D# 62 mGluR5 antagonist 62 V#F mutation 62 cytochrome P# 62 apoptotic pathway 62 TrkA 62 synthetic analogues 62 angiogenesis inhibitor 62 endothelin receptor 62 deacetylase inhibitors 61 cytotoxin 61 demethylating agent 61 Notch receptors 61 PDE4 inhibitors 61 bioactive lipids 61 TNF receptors 61 JAK2 inhibitors 61 pro apoptotic 61 siRNA therapeutics 61 neurokinin 1 61 PKC inhibitor 61 2 methoxyestradiol 61 subtype selective 61 receptor subtype 61 SOD1 61 FK# 61 cystic fibrosis transmembrane conductance 61 nicotinic receptor 61 PDE# 61 HuLuc# 61 JAK2 61 factor kappa B 61 receptor gamma 61 MetAP2 61 oncoprotein 61 nAChR 61 inhibit tumor 61 PSN# [002] 61 #beta HSD1 61 NFκB 61 G Protein Coupled 61 PC# cells 61 dAbs 61 selective adenosine 61 microRNA miRNA 61 MDSCs 61 Pegylated 61 NMDA N 61 chemopreventive 61 ADP receptor antagonist 61 vinca alkaloid 61 Tumor Necrosis Factor 61 PDE#A 61 humanized anti 61 CYC# 61 retaspimycin 61 alkylating agent 61 PI3K inhibitors 61 MEK1 61 anti angiogenic 61 modulators SERMs 61 CDK4 61 PIK3CA 61 Epratuzumab 61 eicosanoid 61 A3 adenosine receptor 61 cannabinoid receptor 61 heparanase 61 JAK#/JAK# 61 XL# inhibits 61 effector function 61 Y2 receptor 61 Hedgehog signaling pathway 61 Enzastaurin 61 secreted protein 61 fusion proteins 61 phosphoinositide 3 61 antisense oligonucleotides 61 olaparib 61 nucleosides 61 mediated apoptosis 61 Aplidin 61 promoter methylation 61 biased ligands 61 substrates inhibitors 61 5 HT6 61 cytokine signaling 61 antimetastatic 61 DFMO 61 miR #a [001] 61 LPA1 receptor 61 AMPK activators 61 Selective Inhibitor 61 BMP2 61 endoplasmic reticulum stress 61 NMDA antagonists 61 GRP# 61 beta adrenergic 61 miRNAs 61 imatinib Gleevec ® 61 agonist compounds 61 RNA silencing 61 demethylase 61 5 HT2A receptor 61 liposomal formulation 61 mTOR mammalian target 61 neuronal nicotinic receptors NNRs 61 monoclonal antibody MAb 61 highly selective endothelin 61 IL #R 61 PI3K 61 cisplatin resistant 61 benzimidazole 61 ERa 61 Kv#.# 61 tiapamil 61 thyroid hormone receptor 61 aberrantly activated 61 protein tyrosine phosphatases 61 inhibit metastasis 61 HGS ETR1 mapatumumab 61 myeloproliferative disorders 61 tumorigenic 61 cytokine IL 61 Zolinza 61 glioma cells 61 Anticalins R 61 CCL# 61 pRb 61 nicotinic acetylcholine receptor 61 neuro protective 61 reverse transcriptase inhibitors 61 cytotoxic 61 Abeta peptide 61 MAPK pathway 61 PARP inhibitor 61 AMN# [001] 61 LRP6 61 IGFBP2 61 GMX# 61 mitotic kinesins 61 polymerase inhibitors 61 glycogen synthase kinase 61 small molecule 61 OXi# 61 NNR Therapeutics 61 ABCA1 61 alpha#beta# integrin 61 tyrosine phosphorylation 61 tumor vasculature 61 PPAR gamma agonists 61 receptor tyrosine kinase 61 SCD1 61 dihydrofolate reductase 61 chemotherapeutics 61 Nanobodies 61 MDM2 61 galectin 3 61 JAK2 mutation 61 miR #b [002] 61 NMDA receptor 61 tubulin binding 61 EGFR TKIs 61 autoreactive T cells 61 beta arrestin 61 WT1 61 interferon IFN 61 preclinically 61 multitargeted 61 eIF 4E 61 serotonin reuptake 61 novel immunomodulatory 61 uricase 61 interferons 61 c myc 61 microtubule inhibitor 61 RNA antagonist 61 Alfacell proprietary ribonuclease 61 peroxidase 61 TRAIL R2 61 Flt3 61 USP# 61 ErbB 61 HGS# 61 Vidaza ® 61 Li Fraumeni 61 SGLT inhibitors 61 polyketide 61 anti secretory 61 IGFBP 3 61 ErbB2 61 mutational status 61 peptide hormone 61 protein encoded 61 kidney urologic 61 antisense oligonucleotide 61 bortezomib Velcade 61 alpha#beta# 61 cytokine receptors 61 ß catenin 61 potent antiproliferative 61 CGRP 61 NF kB pathway 61 Crizotinib 61 mitochondrial toxicity 61 Aurora kinase inhibitor 61 preclinical compounds 61 direct thrombin inhibitors 61 Th2 cytokines 61 BCR ABL inhibitors 61 receptor activator 61 myeloma cells 61 reuptake inhibitors 61 Skp2 61 muscarinic 61 inhibiting tumor 61 RAF kinase 61 redox active 61 Onconase 61 molecular biomarkers 61 irreversible inhibitor 61 oxidative stress inducer 61 S#P# 61 Gefitinib 61 Pentad TM 61 Methylnaltrexone 61 Carfilzomib 61 E selectin 61 leukotriene pathway 61 DXL# 61 Bafetinib 61 PEGylated Fab fragment 61 genetic biomarkers 61 gastrin 61 nitric oxide synthase 61 agonism 61 short hairpin RNAs 61 HER2 receptors 61 humanized monoclonal antibody 61 p# activation 60 #D#C# 60 ansamycin 60 vesicular monoamine transporter 60 Eg5 60 TLR7 60 alkylating 60 acetylcholine receptor 60 protein mTOR 60 neuroinflammation 60 mediated inhibition 60 TGFBR1 * 6A 60 transgenic mouse models 60 tyrosine kinases 60 apoE 60 tubulin inhibitor 60 genes encoding 60 TLR8 agonist 60 antiproliferative activity 60 immuno modulatory 60 HIF 1α 60 adhesion molecule 60 Pertuzumab 60 progesterone receptor 60 heterodimers 60 non nucleoside 60 siRNA mediated 60 CXCR4 60 methyl D aspartate 60 ALN TTR# 60 RANK Ligand 60 IGF1R 60 T#M 60 TGF beta1 60 NTDDS 60 neurofibromin 60 Seliciclib 60 TGF ß 60 Monoclonal Antibody 60 drug metabolizing enzymes 60 TLR9 agonists 60 PKC# 60 GABA receptors 60 chemotherapeutic drugs 60 peptibody 60 CCR9 60 β catenin 60 plectasin 60 nucleotide analogs 60 Trp p8 60 PRT# 60 TLE3 60 CRAC channel 60 inhibits protein synthesis 60 cytostatic 60 beta subunit 60 ghrelin receptor 60 antifibrotic 60 IL 1ß 60 Aurora Kinase 60 hydrolases 60 UsiRNAs 60 antitumour 60 5 HT4 60 tumor subtypes 60 prostaglandin synthesis 60 potent cytotoxic 60 IL #p# 60 clusterin 60 MCSP respectively 60 multikinase inhibitor 60 immunostimulatory 60 CRF1 receptor 60 viral proteins 60 peptidic 60 immunomodulator 60 trans splicing 60 prostaglandin D2 60 oligodendrocyte precursor cells 60 related apoptosis inducing 60 Debio 60 GKAs 60 fosbretabulin 60 Neuropeptide Y 60 MMP2 60 imatinib resistance 60 signaling pathway 60 siRNA therapeutic 60 incretin 60 oncolytic virus 60 myelofibrosis polycythemia vera 60 Granulocyte Colony Stimulating Factor 60 fibrotic disease 60 TNF α 60 antiproliferative 60 5 HT2A 60 investigational pan BCR 60 mitogen activated protein 60 cediranib 60 casein kinase 60 IMA# 60 demethylating agents 60 ArQule Kinase Inhibitor Platform 60 mechanistic insights 60 intracellular pathways 60 Darinaparsin 60 MUC1 60 protein tyrosine 60 antitumor effect 60 protein kinase inhibitors 60 tumor suppressor proteins 60 IFNs 60 selective estrogen receptor modulators 60 Fc receptor 60 TNFα 60 Syk 60 Angiotensin 60 Azedra 60 antidepressants SSRIs 60 JAK2 enzyme 60 DNA methyltransferases 60 sorafenib Nexavar 60 monocyte chemotactic protein 60 PLX cells 60 vanilloid receptor 60 polyamine 60 inhibitor PPI 60 activin 60 selective androgen receptor modulators 60 BRAF kinase 60 small interfering RNA 60 neurosteroid 60 proteases 60 ErbB3 HER3 60 cytotoxic T 60 sphingosine kinase 60 mTOR inhibitor 60 oncolytic viruses 60 caveolin 1 60 Orally administered 60 inhibitor COX 60 serine proteases 60 deacetylation 60 CXCL5 60 anaplastic lymphoma kinase ALK 60 anti angiogenic drugs 60 depsipeptide 60 PEGylated 60 Liposomal 60 MGd 60 thiazolides 60 2 inhibitor CYT# 60 microRNAs 60 BCL2 60 prolyl 60 Interferon gamma 60 mimetics 60 effector functions 60 monocytic 60 Factor VIIa 60 monoclonal anti 60 riociguat 60 5 HT1A 60 FTIs 60 novel kinase inhibitors 60 nucleoside analog 60 hERG 60 selectively inhibiting 60 cancer immunotherapies 60 breast cancer subtypes 60 PDE4 60 vitro studies 60 nNOS 60 targeted radiotherapeutic 60 Panzem R NCD 60 proliferative disorders 60 fatty acid biosynthesis 60 Interferon Beta 60 histone deacetylation 60 uPA 60 chemokine receptors 60 LIS1 60 TAp# 60 antineoplastic 60 cyclic peptide 60 transcription factors 60 PPAR 60 Ceflatonin 60 Bortezomib 60 non steroidal 60 engineered RAP peptides 60 hTERT 60 CTAP# Capsules 60 antiangiogenic activity 60 plasminogen 60 cyclophilin inhibitor 60 demonstrated antitumor activity 60 selective immunoproteasome inhibitor 60 kinase PI3K 60 PDE1 60 Angiotensin Converting Enzyme 60 TNFalpha 60 granzyme B 60 estrogen receptor 60 M2 subunit 60 neuroblastoma tumors 60 ANGPTL4 60 alvespimycin 60 NR2B selective 60 retinoid 60 trastuzumab Herceptin 60 Akt1 60 Olaparib 60 anticoagulant reversing agent 60 Sertoli cell 60 COX inhibitors 60 receptor blockers 60 RRM1 60 nucleoside analogue 60 Omacetaxine 60 UCP2 60 HCV protease inhibitors 60 channel blockers 60 anticancer activity 60 synthetase 60 oncomodulin 60 glycolipids 60 Monoclonal antibodies 60 SIRT1 activators 60 alpha synuclein gene 60 NKG2D 60 thalidomide Thalomid 60 targeted antifolate 60 tarenflurbil 60 mineralocorticoid receptor 60 inhibit KSP 60 HCV replicon 60 bacterial enzyme 60 GRK2 60 RNA antagonists 60 proliferator activated receptor 60 CTGF 60 cAMP signaling 60 tumor antigen 60 D aspartic acid 60 tropomyosin 60 chemically modified siRNA 60 neurite outgrowth 60 cardiac toxicity 60 nicotinamide 60 histone deacetylase HDAC inhibitor 60 isoform 60 azoles 60 allosteric 60 P#X# receptor 60 eIF4E 60 GPR# agonists 60 synovial cells 60 TGR5 60 tumor suppressors 60 superficial bladder cancer 60 aurora kinase 60 oxazolidinone 60 2DG 60 mTOR pathway 60 anti angiogenic agents 60 virulence genes 60 VEGF pathway 60 Androgen Receptor 60 agonists 60 arginase 60 inhibit replication 60 CTLA4 Ig 60 assay detects 60 synthetic siRNA 60 echinocandins 60 covalent drugs 60 stem cell pluripotency 59 isotypes 59 phosphoprotein 59 immunotoxin 59 Protein Kinase 59 anionic backbone 59 C5aR