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(Click for frequent words.) 76 splice variant 75 mRNA transcripts 74 sequence homology 73 RRM1 73 substrate specificity 73 FLT3 73 constitutively expressed 73 missense mutations 73 isotypes 72 tumorigenicity 72 glycosylated 72 gene loci 72 cDNAs 72 potent inhibitors 72 ncRNA 71 serine protease 71 pharmacodynamic biomarkers 71 homodimers 71 thymidylate synthase TS 71 orthologs 71 non coding RNA 71 subcellular localization 71 microRNA expression 71 Cathepsin B 71 splice junctions 71 miRNA expression 71 tyrosine phosphorylation 71 intergenic regions 71 genetic loci 71 methyltransferases 71 Clusterin 71 nucleotide sequence 71 replicon 71 Upregulation 71 immunoregulatory 71 K ras mutations 71 promoter methylation 70 heterodimers 70 secreted proteins 70 androgen receptor AR 70 MAPK pathway 70 Anticalins R 70 siRNAs targeting 70 molecular biomarkers 70 gene expression microarrays 70 V#F mutation 70 potently inhibit 70 homologues 70 gene rearrangements 70 paralogs 70 virulence genes 70 mutational status 70 mRNA expression 70 miRNA molecules 70 proto oncogene 70 ubiquitin ligases 70 short hairpin RNAs 70 FUS1 70 adipogenic 70 isoforms 70 #S rRNA 70 pharmacodynamic markers 70 nucleotide sequences 70 Sertoli cell 70 causal variants 70 transcriptional regulation 70 TMPRSS2 ERG 70 hypermethylated 70 adenoviral 70 Eg5 70 mediated inhibition 70 somatostatin 70 drug metabolizing enzymes 69 RNA polymerases 69 somatic mutations 69 E#F# 69 NS5A 69 silico prediction 69 eTag assays 69 TMPRSS2 ERG fusion 69 preclinically 69 #S rRNA gene 69 KLF4 69 sphingolipid 69 differentially expressed genes 69 mRNA molecules 69 ORFs 69 bacterial genomes 69 transgene expression 69 RNA transcripts 69 synthases 69 Fibroblast Growth Factor Receptor 69 MDR1 69 miRNA genes 69 outer membrane proteins 69 phosphate S1P 69 proteins encoded 69 glycolipids 69 transcriptomes 69 ribonucleic acids 69 cyclin dependent kinase inhibitor 69 DNA demethylation 69 genes encoding 69 P2X 69 coexpression 69 methylated DNA 69 inactivating mutations 69 noncoding RNA 69 genomic loci 69 experimentally validated 69 genomic alterations 69 ribosomal proteins 69 DNMT1 69 posttranslational modifications 69 serine threonine kinase 69 ENMD # 69 IL #p# 69 TTR gene 69 phylogenetic analyzes 69 uPAR 69 PIK3CA 68 COL#A# 68 FGFR2 68 ZNF# 68 Cyclin E 68 antisense oligonucleotides 68 H#K#me# 68 Anticalins ® 68 granzyme B 68 myeloproliferative diseases 68 antisense inhibitors 68 evolutionarily conserved 68 c KIT 68 amyloidogenic 68 KIAA# 68 peptide antigens 68 proteolytic cleavage 68 protein tyrosine phosphatase 68 antiproliferative activity 68 cytokine receptor 68 CDK4 68 peptide receptor 68 TMEM#B 68 Alu elements 68 subcellular compartments 68 rRNA 68 Rap1 68 tyrosine kinase receptor 68 phosphoprotein 68 #T# L1 68 SIRT2 68 TGF alpha 68 neuroligins 68 CpG island 68 c MYC 68 histone deacetylase HDAC 68 XL# inhibits 68 Activating mutations 68 noncoding RNAs 68 Flt3 68 prolyl 68 antiapoptotic 68 cell adhesion molecule 68 mutational analysis 68 transcriptome sequencing 68 potent inhibition 68 induce apoptosis 68 A3 adenosine receptor 68 post translational modifications 68 gene inactivation 68 differentially regulated 68 isotype 68 oncoproteins 68 biologic pathway 68 endogenous ligands 68 hepatoma 68 cMET 68 siRNA duplexes 68 epithelial tumors 68 shRNAs 68 downstream effectors 68 nucleotide substitutions 68 PKM2 68 ABCB1 68 enolase 68 amplicons 68 4E BP1 68 metalloprotease 68 histone modifications 68 multiplex assay 68 ribosomal protein 68 operon 68 vivo potency 67 prognostic markers 67 N acetyltransferase 67 p# MAPK 67 serine threonine 67 immunohistochemical analysis 67 transfected cells 67 BMP2 67 beta actin 67 cis regulatory 67 RNA sequences 67 tumor antigen 67 neurite outgrowth 67 HIF 1alpha 67 assay detects 67 siRNA knockdown 67 HepG2 cells 67 chromatin immunoprecipitation ChIP 67 histone acetyltransferase 67 p# activation 67 Nedd4 67 functional polymorphism 67 CCR3 67 prion strains 67 mRNA sequences 67 lymphoid cells 67 HCV replicon 67 humanized monoclonal antibodies 67 GPx 67 eukaryotic genomes 67 endophenotypes 67 nucleolin 67 methylation patterns 67 CXCL5 67 Protein Kinase C 67 siRNA sequences 67 HEK# cells 67 Janus kinase 67 constitutively active 67 NKX#.# 67 Immunohistochemical analysis 67 ERK signaling 67 RNAi mediated 67 anti CD3 67 ERK1 2 67 tubulin inhibitor 67 CD#b 67 downregulated 67 Arabidopsis genes 67 ChIP chip 67 histone acetylation 67 stably transfected 67 aurora kinase 67 activating mutation 67 PTPN# 67 thymidine kinase 67 TRAIL induced apoptosis 67 DLC1 67 EphB4 67 MSH2 67 metabolomic profiles 67 BCR ABL1 67 HAAH 67 dimerization 67 glycosylation profile 67 cellular pathways 67 kinase inhibition 67 phosphatases 67 miR #a [001] 67 LIS1 67 protein kinases 67 Annexin V 67 MLH1 67 gene locus 67 protein isoforms 67 Fas ligand 67 gene polymorphisms 67 cathepsins 67 BRAF V#E 67 KRAS oncogene 67 biochemical assays 67 Drosha 67 novel VDA molecule 67 EGFR HER2 67 Cdc7 67 tumor specific antigen 67 IFN γ 67 chromosomal regions 67 trans splicing 67 CHO K1 67 operons 67 CagA 67 osteogenic 67 nucleolar 67 immunoblotting 67 antiangiogenic activity 67 ChIP seq 67 phosphorylated proteins 67 miRNAs miR 67 cytokine receptors 67 proapoptotic 67 interferon IFN 66 siRNA mediated 66 bisulfite sequencing 66 coding exons 66 Western blotting 66 shRNA libraries 66 T#M 66 susceptibility loci 66 HER2 HER2 66 chromosomal translocations 66 stem cell pluripotency 66 orthologous 66 pathogenic mutations 66 microRNA molecules 66 transiently transfected 66 IgG1 66 hypomethylation 66 quantitative PCR 66 hTERT 66 STK# [002] 66 mitogen activated protein kinase 66 CRAC channel 66 ncRNAs 66 HLA alleles 66 GSTP1 66 thioredoxin 66 cyclic AMP cAMP 66 alternatively spliced 66 mda 7 66 PI3K Akt 66 activating mutations 66 pDC 66 molecular abnormalities 66 M. pneumoniae 66 FGFs 66 transmembrane protein 66 diagnostic biomarker 66 eIF 4E 66 DNA methyltransferases 66 lysates 66 polynucleotide 66 selectively inhibited 66 enzymatically active 66 BCL2 66 selective antagonists 66 folate receptor 66 tryptase 66 orally administered inhibitor 66 transfection efficiency 66 γ secretase 66 ortholog 66 ADAMTS# 66 coding genes 66 succinate dehydrogenase 66 HCV protease 66 p# mitogen activated 66 β1 66 c MET 66 maternally inherited 66 viral genomes 66 cysteine residues 66 hypermethylation 66 protein ligand 66 UsiRNAs 66 RAS RAF MEK 66 pro angiogenic 66 binding affinities 66 CD#c 66 #beta HSD1 66 p# subunit 66 intronic 66 TLR9 agonists 66 germline mutations 66 histone H3 66 protein biosynthesis 66 Anticalin ® 66 untranslated regions 66 lysine residues 66 ABL1 66 immunofluorescence staining 66 ERBB2 66 GPR# [002] 66 IMPDH 66 meganuclease 66 MLL2 66 PDGFR 66 quantitative PCR qPCR 66 spontaneous mutations 66 comparative genomic hybridization 66 receptor subtypes 66 microRNAs miRNAs 66 T#I [002] 66 vivo validation 66 #q#.# [002] 66 astrocytic 66 VIPR2 66 LRP5 66 transgenic mouse models 66 LRAT 66 globin genes 66 small molecule modulators 66 sPLA2 66 VEGF receptor 66 Xanafide 66 cyclin dependent kinases CDKs 66 Symadex 66 Leydig cells 66 DNA methylation patterns 66 apoptosis pathway 66 therapeutically relevant 66 ERK1 66 NSCLC tumors 66 Drosophila genome 66 TÎ ² 4 66 circulating endothelial cells 66 microarray gene expression 66 MCSP respectively 66 protein tyrosine phosphatases 66 prognostic biomarker 66 cyclin E 66 constitutively 66 CCR2 66 polypeptides 66 isoenzymes 66 FasL 66 druggable targets 66 quantitative trait loci 66 ERK2 66 qRT PCR 66 microarray experiments 66 RUNX3 66 extracellular domain 66 perilipin 66 5 HT4 receptor 66 mitotic kinesin 66 transferase 66 EphA2 66 Microarray analysis 66 CYP#C# [002] 66 recombinants 66 H#K# [002] 66 phosphorylate 66 intracellular protein 66 5 hmC 66 phenotypic expression 66 PKC isoforms 66 chromosomal aberrations 66 microRNA biomarkers 66 adenylate cyclase 66 co stimulatory molecules 66 transduced 66 RefSeq 66 FKBP# 66 annexin 66 gene amplification 66 triphosphate 66 potently inhibited 66 cytochrome b 66 poly ADP ribose polymerase 66 histone deacetylases 66 previously uncharacterized 66 RT qPCR 66 micro RNAs 66 CCR1 66 HER2 expression 66 small molecule agonists 66 chemokine receptor 66 immune stimulatory 66 serum biomarkers 65 PDGF receptor 65 intracellular bacteria 65 Akt activation 65 Htt 65 DNA methyltransferase 65 cDNA microarray 65 ligand binding 65 transmembrane 65 chromosome #p#.# 65 deacetylase 65 Wnt signaling pathway 65 TIMP 1 65 CEACAM1 65 cathepsin B 65 miR #b [002] 65 PCA3 gene 65 selective inhibitors 65 effector function 65 GPI anchored 65 anionic backbone 65 LNP formulations 65 methylation markers 65 glycolytic 65 L. pneumophila 65 cytotoxicity assays 65 retinoic acid receptor 65 GlcNAc 65 constitutively activated 65 NS4A 65 tropomyosin 65 protein tyrosine kinase 65 intergenic 65 gastric carcinoma 65 TAp# 65 mitochondrial gene 65 ALK mutations 65 UGT#A# 65 synthetase 65 proteomic analysis 65 pyrimidine 65 PPARg 65 Factor Receptor 65 peroxisomal 65 ankyrin repeat 65 pleiotropic effects 65 amino acid sequence 65 C#T [002] 65 VSV G 65 genotypic 65 transgenic mice expressing 65 Klf4 65 miRNAs 65 uricase 65 PI3 kinase 65 conserved sequences 65 breast cancer subtypes 65 Aurora kinase 65 prodrugs 65 non nucleoside 65 NS#/#A protease 65 MAP kinase 65 AGTR1 65 TNFR1 65 lysosomal 65 chromosomal rearrangement 65 EGFRvIII 65 phenotypic variation 65 proinflammatory mediators 65 pDCs 65 IL 1β 65 CDK inhibitor 65 cell lysates 65 PALB2 65 apoE 65 EGFR mutant 65 picomolar 65 DEAR1 65 Supplementary Fig 65 RNA antagonist 65 de novo sequencing 65 pleiotropic 65 ribosomal RNA rRNA 65 uncharacterized 65 immunological responses 65 c myb 65 Chinese Hamster Ovary 65 Bt toxins 65 geldanamycin 65 TIMP 65 deacetylation 65 mitotic kinesins 65 heparanase 65 AMACR 65 oncogenic transformation 65 epithelial tissues 65 amino acid substitutions 65 metalloproteins 65 homologs 65 rxRNA compounds 65 IGFBP2 65 eicosanoid 65 prostanoid 65 HERmark assay 65 miR #a [002] 65 TLR8 65 NS5B 65 synthetic analogues 65 heterozygotes 65 proteoglycan 65 SIRT1 activators 65 CD# CD# 65 anticancer therapeutics 65 JAK#/JAK# 65 SOD1 gene 65 proteomes 65 CD1d 65 homodimer 65 Fc receptor 65 HER2 overexpression 65 survivin 65 chemokine receptors 65 vimentin 65 circadian genes 65 JNK1 65 mTOR inhibitors 65 #ß 65 primate genomes 65 molecular biomarker 65 plasma pharmacokinetics 65 CYT# potent vascular disrupting 65 FGFR4 65 HIF 1α 65 SNP arrays 65 genomic biomarkers 65 EGFR protein 65 metabolic enzymes 65 peptide sequences 65 #S rRNA genes 65 5 HT2A serotonin 65 PHD2 65 histone deacetylase inhibitor 65 GABAB receptors 65 homeobox gene 65 DLX5 65 PKCi 65 isoenzyme 65 indels 65 C1q 65 anterior pituitary 65 xenograft models 65 hydrolases 65 Immunohistochemical staining 65 glutamic acid decarboxylase 65 K#R [002] 65 At#g# 65 ANGPTL4 65 protein tyrosine phosphatase 1B 65 interferon lambda 65 cyclin dependent kinase 65 PTP 1B 65 HER2 neu 65 mtDNA mutations 65 tumor biopsies 65 tumor subtypes 65 multiplexed assays 65 enzymatic reactions 65 transient receptor 65 CCR9 65 Polymorphisms 65 autism susceptibility genes 65 cytolytic activity 65 preferentially bind 65 biomarker identification 65 potently inhibits 65 methylenetetrahydrofolate reductase 65 GSOs 65 transcriptomic 65 peripheral blood mononuclear 65 p# INK4a 65 tRNA synthetase 65 Jhdm2a 65 Abeta# 65 murine models 65 myeloproliferative disorders 65 physico chemical properties 65 mechanistic insights 65 microsomal 65 partial agonists 65 hypoxia inducible factor 65 histone modification 65 TLE3 65 putative biomarkers 65 TNFalpha 65 IL 1ß 65 mutant alleles 65 immunostaining 65 Affibody ® molecules 65 ENaC 65 CCR7 65 nanomolar 65 pathophysiological effects 65 IFN g 65 immunoglobulin genes 65 reverse transcriptase inhibitors 65 hENT1 65 N glycan 65 WT1 65 USP# 65 ERK pathway 65 receptor ligand 65 antiproliferative effects 65 Synuclein 65 mutated p# 65 differentially expressed proteins 65 nutlin 3a 65 diagnostic biomarkers 65 synuclein 65 cytosolic 65 MTHFR 64 oligonucleotide arrays 64 galectin 64 epigenetic modification 64 transcriptional activation 64 Transcriptome 64 antagomirs 64 telomerase inhibitor 64 neuronal dysfunction 64 secretory pathway 64 ribosomal DNA 64 GAGs 64 replicase 64 5alpha reductase 64 Trp p8 64 granzyme 64 VKORC1 64 Histone 64 lymphoblastoid cell lines 64 3'UTR 64 ultrastructure 64 microglial activation 64 #S rDNA 64 ETBs 64 gp# protein [002] 64 transactivation 64 Tie2 64 epigenetic regulation 64 differential gene expression 64 colocalization 64 acetylcholine receptor 64 Cre recombinase 64 alpha#beta# integrin 64 acyl CoA 64 carboxyl terminal 64 Leydig cell 64 NPM1 64 HLA DR 64 syngeneic 64 EBNA1 64 selective inhibition 64 protein encoded 64 allelic variants 64 beta tubulin 64 PAX5 64 thrombin receptor 64 aspartyl 64 somatic mutation 64 monoclonal antibody mAb 64 IL #E 64 peptide ligands 64 matrix metalloproteinases 64 A. thaliana 64 carcinoembryonic antigen 64 papillary renal cell carcinoma 64 genes encode 64 5 hydroxymethylcytosine 64 polyclonal 64 kDa protein 64 FGFR 64 HLA molecules 64 c myc 64 cyclooxygenase COX 64 chloroplast genome 64 MTT assay 64 tumor xenograft models 64 chaperone proteins 64 extracellular domains 64 PDE#A 64 hydroxylase 64 etiologic 64 phospholipase 64 mutated K ras 64 oligomerization 64 JAK2 enzyme 64 CD# CEA 64 mitogen activated protein kinases 64 genetic polymorphisms 64 eIF4E 64 herpesviruses 64 SLC#A# [002] 64 BMAL1 64 cell lysate 64 short hairpin RNA 64 VEGFR1 64 messenger ribonucleic acid 64 haematopoietic 64 cell signaling pathways 64 FGFR1 64 binds selectively 64 Genotypes 64 non nucleoside HCV 64 transmembrane proteins 64 HER2 HER3 64 Tr DNA 64 miRs 64 Notch receptors 64 chromatin structure 64 ribonuclease 64 miRNA sequences 64 IL #R 64 single stranded oligonucleotides 64 allelic 64 normal karyotype 64 Transgenic Mice 64 transfection reagents 64 intercellular signaling 64 PDGF B 64 cyclins 64 NFκB 64 cellular prion protein 64 μ opioid receptor 64 tumor suppressor protein 64 IGF IR 64 MAPCs 64 rs# [004] 64 ligases 64 colon carcinoma 64 cDNA libraries 64 genes differentially expressed 64 hematopoietic cells 64 epistasis 64 inhibitory effects 64 Mechanistic studies 64 pRb 64 cytoprotective 64 BCR ABL 64 anaphase promoting complex 64 tumor antigens 64 tRNA synthetases 64 indel 64 cationic lipid 64 histone demethylase 64 FGFR3 64 glycan structures 64 reaction PCR 64 NPM1 mutations 64 immunohistochemical 64 redox active 64 mammalian proteins 64 coactivator 64 unmutated 64 Alfacell proprietary ribonuclease 64 K RAS 64 gene expression assays 64 Nod1 64 kinesin spindle protein 64 validate biomarkers 64 nicotinic receptor 64 causative mutations 64 Sanger sequencing 64 miRview mets 64 vitro assay 64 effector molecules 64 JAK3 64 iNOS 64 Dpp 64 gastric carcinomas 64 receptor tyrosine kinase 64 polyadenylation 64 monoclonal antibodies mAbs 64 small molecule defensin 64 miRNA biomarkers 64 HIF 1a 64 NOD SCID mice 64 biosynthetic pathway 64 induce pluripotency 64 matrix metalloproteases 64 Kinases 64 vacuolar 64 antitumor 64 oligomeric 64 CXCR7 64 genotyping arrays 64 amino acid substitution 64 virulence determinants 64 QTLs 64 HbF 64 heterologous expression 64 AhR 64 MMP# 64 MT1 MMP 64 mesothelin 64 PITX2 64 polyamine 64 JAK inhibitors 64 histocompatibility 64 DGAT1 64 viral proteins 64 modifier genes 64 polymorphisms 64 PI3K/mTOR 64 molecular determinants 64 chromatin immunoprecipitation 64 kinase domain 64 PML RARA 64 Pgp 64 polypeptide 64 quasispecies 64 biophysical techniques 64 costimulatory 64 QTL mapping 64 CCX# 64 alpha7 64 HLA DQ2 64 EF Tu 64 HCV replication 64 lentiviral vectors 64 cytoplasmic domain 64 EAAT2 64 1α 64 RNA binding 64 induces apoptosis 64 secreted protein 64 cyclase 64 ALK inhibitors 64 flow cytometric 64 resistant mutants 64 microdeletions 64 PTEN gene 64 Prox1 64 druggable target 64 TXNIP 64 polycystin 64 serum antibodies 64 optical biosensors 64 efflux pump 64 mammalian genomes 64 nAChR 64 paxillin 64 MALDI-TOF/TOF 64 organophosphorus compounds 64 autoantigens 64 C#Y 64 signaling cascades 64 proliferative disorders 64 monocytic 64 CENP E 64 Foxp3 64 neuropilin 64 peroxidase 64 HBx 64 HDACs 64 metazoan 64 metabolizing enzymes 64 monomeric 64 osteopontin OPN 64 dAbs 64 clonally 64 interleukin IL 64 nucleated cells 64 DHPLC 64 biomolecular interactions 64 PET tracers 64 SMAD4 64 prodynorphin 64 p# deficient 64 sRNA 64 antibody arrays 64 gastrointestinal stromal tumors GISTs 64 annexin V 64 ligase 64 selectively inhibits 64 Secretase 64 genomic sequence 64 HepDirect prodrug 64 #beta HSD 1 64 β amyloid 64 vascular disrupting agents 64 RAR beta 64 polyketides 64 lysophosphatidic acid LPA 64 Aromatase 64 antisense inhibition 64 cyclin dependent kinases 64 pathogenic mechanisms 64 TRAIL receptor 64 cAMP signaling 64 apoptotic pathway 64 enzyme inhibition 64 polyploid 64 uniparental 64 molecular subtypes 64 proteinase 64 undifferentiated hESCs 64 transcriptional repression 64 Overexpression 64 therapeutic monoclonal antibodies 64 ZFP TFs 64 Syk 64 Smad3 64 GLUT1 64 heterologous 64 engineered RAP peptides 64 inverse agonist 64 CDKN2A 64 PBMCs 64 NOD mouse 64 methyltransferase 64 OGG1 64 Preclinical studies suggest 64 prostate carcinoma 64 OvaRex R 64 Tubulin 63 Treg cell 63 transcriptional regulators 63 PB1 F2 63 transmembrane domains 63 ligand receptor 63 lymphoid tumors 63 nucleases 63 coding sequences 63 inhibitory receptor 63 decarboxylase 63 kinase assay 63 caveolin 1 63 florbetaben 63 nucleic acid molecules 63 phenotypic traits