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(Click for frequent words.) 74 sequence homology 73 serine protease 73 splice variants 72 transmembrane 72 CD1d 72 glycosyltransferase 72 synthases 72 posttranslational modifications 72 histone H3 72 beta subunit 72 MT1 MMP 72 coexpression 71 lysine residues 71 transgene expression 71 methylated DNA 71 catenin 71 methyltransferase 71 SIRT2 71 homodimer 71 homodimers 71 transmembrane protein 71 ERK1 2 71 subcellular localization 71 vimentin 70 endonuclease 70 transcriptional repressor 70 mRNA expression 70 dimerization 70 isoforms 70 glycosylation 70 Rap1 70 metabolic enzymes 70 pRb 70 immunoregulatory 70 KLF4 70 phosphoprotein 70 transcriptional activation 70 Nedd4 70 glycosylated 70 c myc 70 VE cadherin 70 proteolysis 70 syntaxin 70 constitutively expressed 70 6S RNA 69 nucleolar 69 outer membrane proteins 69 evolutionarily conserved 69 cytochrome 69 paralogs 69 phosphatase 69 kD 69 constitutively active 69 DNMT1 69 dimeric 69 triphosphate 69 androgen receptor AR 69 synthetase 69 Vps# 69 drug metabolizing enzymes 69 secretory pathway 69 reductase 69 tyrosine phosphorylation 69 EGFP 69 kinase domain 69 IL 1β 69 homologs 69 phosphatidylinositol 69 operon 69 subcellular compartments 69 hexose 69 oligomeric 69 polyamine 69 ERK signaling 69 H#K#me# 69 vesicle fusion 69 glycolipids 69 activin 69 cytokine receptors 69 phosphorylates 69 granzyme B 69 polycystin 69 β1 69 MDR1 69 isotypes 69 secretase 69 photosystem II 69 ribosomal protein 69 kDa protein 69 tetramer 69 P selectin 69 COL#A# 69 transferase 69 transgenic mice expressing 69 amino acid residue 69 serpin 69 Rab5 69 virulence genes 69 GAPDH 69 adduct 69 antiapoptotic 69 replicase 69 NADPH 69 aggrecan 69 MMP# 69 phosphatases 69 nucleotide sequence 69 TGF ß 69 ubiquitylation 69 oligomer 69 uPAR 69 EBNA1 69 rRNA 69 monomeric 69 thymidine 69 biosynthetic pathway 68 phospholipase 68 cysteine residues 68 enzymatic activity 68 5 hydroxymethylcytosine 68 transcriptional regulation 68 missense mutations 68 Amino acid 68 Alu elements 68 carcinoembryonic antigen 68 ciliated 68 amino acid residues 68 E#F# 68 vacuolar 68 E1A 68 constitutively 68 tropomyosin 68 miR# 68 adipogenic 68 isoenzyme 68 carboxyl terminal 68 caveolin 1 68 binding affinities 68 PTPN# 68 scavenger receptor 68 disulfide 68 RAR beta 68 SMN1 68 cytoplasmic domain 68 tumorigenicity 68 amino acid sequence 68 proteolytic cleavage 68 RRM1 68 heterodimers 68 hnRNP 68 apoE 68 ubiquitinated 68 uracil 68 VEGF receptor 68 mediated inhibition 68 morphogen 68 dinucleotide 68 osteoblast 68 At#g# 68 cell adhesion molecule 68 BMP2 68 E3 ligase 68 receptor subtypes 68 oligomerization 68 RNA sequences 68 F actin 68 tumor antigen 68 isoenzymes 68 5' triphosphate 68 microglial activation 68 protein tyrosine phosphatase 68 biotinylated 68 proteolytic 68 GPx 68 Cytochrome 68 Pgp 68 genes encoding 68 beta globin 68 HEK# cells 68 GPI anchored 68 amino acid substitutions 68 Western blotting 68 cathepsin B 68 neurite outgrowth 68 DNA methyltransferases 68 carboxylic acid 68 plasminogen 68 T#M 68 gene rearrangements 68 transmembrane domains 68 PPARγ 67 Fas ligand 67 Tubulin 67 phosphorylate 67 hydrolases 67 beta actin 67 SDS PAGE 67 PAK1 67 defensin 67 guanosine 67 proapoptotic 67 annexin V 67 hTERT 67 eukaryotic 67 orthologs 67 cytokine receptor 67 site directed mutagenesis 67 cofactor 67 homolog 67 mitochondrial respiration 67 metaplasia 67 immunoreactivity 67 lysosomal 67 Activating mutations 67 cadherin 67 SUMOylation 67 ERK1 67 ERBB2 67 proto oncogene 67 extracellular domain 67 EphB4 67 transactivation 67 FUS1 67 FGFR3 67 nucleic acid molecules 67 proteoglycan 67 mRNA transcripts 67 endocytic 67 DNA demethylation 67 membrane fusion 67 Klf4 67 fig. S2 67 Fibroblast Growth Factor Receptor 67 epithelia 67 polypeptides 67 quinone 67 CEACAM1 67 glycan structures 67 peroxidase 67 Fig. 4a 67 glomerular 67 cytokeratin 67 mitotic progression 67 phagocytosis 67 transferrin receptor 67 lipoxygenase 67 histone acetylation 67 fig. S1 67 serine threonine 67 miRNA expression 67 MAPK pathway 67 cystic fibrosis transmembrane conductance 67 c MYC 67 MAP kinase 67 telomeric 67 acetylcholine receptor 67 splice variant 67 FLT3 67 acinar 67 beta amyloid peptide 67 paxillin 67 mucins 67 metalloprotease 67 cDNAs 67 alternatively spliced 67 phospho 67 histone deacetylases 67 GABAB receptors 67 TGF beta1 67 nucleolin 67 deacetylation 67 N Myc 67 mitochondrial gene 67 leukemic cell 67 pyrimidine 67 aberrantly activated 67 intracellular Ca 2 67 condensin 67 crystallin 67 TGF β 67 membrane protein 67 TMEM#B 67 Kupffer cells 67 mitochondrial enzyme 67 ligases 67 thymidine kinase 67 p# activation 67 TPMT 67 methyltransferases 67 Histone 67 MnSOD 67 membrane proximal 67 transmembrane receptor 67 actin cytoskeleton 67 amyloid peptides 67 immunofluorescence staining 67 Fc receptor 67 glucocorticoid receptor 67 chromatin structure 67 67 hydroxylation 67 CagA 67 oligosaccharide 67 replicon 67 chemotactic 67 methylation patterns 67 BMP signaling 67 Htt 67 tumor suppressor protein 67 deletion mutant 67 tyrosine residues 67 Smad4 67 DLC1 67 C1q 67 Phosphorylation 67 KCNE2 67 decarboxylase 66 pDCs 66 oxidases 66 endogenous ligand 66 HDAC6 66 histone modifications 66 actin binding 66 FGFR1 66 protein kinase C 66 ADAMTS# 66 antiproliferative activity 66 ribonuclease 66 GAGs 66 ERK2 66 isoform 66 potent inhibitors 66 HepG2 cells 66 mRNA molecules 66 posttranslational modification 66 missense mutation 66 glutamine synthetase 66 Smad3 66 ssDNA 66 Immunohistochemical analysis 66 mPGES 1 66 mitogen activated protein kinase 66 #S proteasome 66 apolipoproteins 66 apical membrane 66 prolyl 66 chaperone proteins 66 TAp# 66 proximal tubule 66 protein fragment 66 thrombospondin 66 radiolabeled 66 heterozygotes 66 Arp2 3 66 thymidylate synthase TS 66 RecA 66 CTLs 66 EGF receptor 66 S. cerevisiae 66 ACh 66 gene locus 66 ligand binding 66 lymphoid cells 66 annexin 66 GPR# [002] 66 Phylogenetic analysis 66 colocalization 66 trophoblast cells 66 GSTP1 66 Cdc7 66 phosphoinositide 66 ß1 66 GlcNAc 66 mRNA decay 66 ATPase 66 pleiotropic 66 matrix metalloproteinases 66 PrP 66 PDGFR 66 lung epithelial cells 66 LDL receptor 66 CXCL# 66 microglial 66 1beta 66 CD# ligand 66 transcriptional regulator 66 neurofilament 66 gene polymorphisms 66 c fos 66 isomerase 66 p#NTR 66 E3 ubiquitin ligase 66 nucleases 66 Leydig cell 66 CD#b 66 phosphorylated proteins 66 JAK STAT 66 heterologous 66 endonucleases 66 ribonucleoprotein 66 nitrogenase 66 proteomic analysis 66 Cre recombinase 66 acyl CoA 66 OGG1 66 peptide antigens 66 haematopoietic 66 enzymatic pathways 66 coactivator 66 cysteines 66 luciferase reporter 66 transfected cells 66 centromeric 66 hydroxylase 66 ZNF# 66 β amyloid 66 coding genes 66 glucan 66 Eg5 66 phosphorylated 66 endogenous ligands 66 micro RNAs 66 protein isoforms 66 Upregulation 66 heparan sulfate 66 homologues 66 transgenic mouse model 66 metabolizing enzymes 66 synuclein 66 leucine zipper 66 histone code 66 protein encoded 66 cytosine 66 dephosphorylation 66 phosphorylase 66 efflux pump 66 ultrastructure 66 enzymatically active 66 endosomal 66 astrocytic 66 synaptotagmin 66 γ secretase 66 hepatoma 66 receptor molecule 66 Aß 66 amino terminal 66 mononuclear 66 focal adhesion kinase FAK 66 transmembrane proteins 66 ribosomal proteins 66 diphosphate 66 IgG1 66 ENaC 66 intramolecular 66 biogenesis 66 immunohistochemical analysis 66 thioredoxin 66 cDNA libraries 66 MTT assay 66 unmethylated DNA 66 sphingolipid 66 dipeptide 66 fluorescence intensity 66 peroxisomal 66 amino acid alanine 66 potent inhibition 66 ABCB1 66 spectrin 66 superfamily 66 p#Kip# 66 nucleotide sequences 66 Gly 66 unmutated 66 substituents 66 osteoclast 66 transcriptional coactivator 66 nitrotyrosine 66 wildtype 66 eIF4E 66 HERV 66 serine 66 druggable target 66 cyclase 66 apoptotic pathway 66 monocytic 66 immunodominant 66 thermodynamic stability 66 PARP1 66 gene inactivation 66 TNFalpha 66 mRNA sequences 66 chemokine receptor 66 IFN γ 66 PDZ domains 66 MTHFR 66 miR #a [002] 66 histidine 66 Fig. 1A 66 thiol 66 LRP5 66 FGFs 65 oncogenic 65 oxidative phosphorylation 65 isoleucine 65 Nod1 65 miR #a [001] 65 focal adhesions 65 antisense oligonucleotide 65 ubiquitination 65 #S rRNA gene 65 Fig. 3a 65 serine threonine kinase 65 intergenic 65 tRNA synthetase 65 allelic variants 65 osteoblastic 65 glycoprotein 65 cyclic nucleotide 65 phenotype 65 P2X 65 p# MAPK 65 transduced 65 NHEJ 65 BMAL1 65 aT cell 65 enolase 65 cyclooxygenase COX 65 SLC#A# [002] 65 MSH2 65 Notch receptor 65 mRNA translation 65 exonuclease 65 kinase gene 65 Supplementary Fig 65 normal prion protein 65 TRPV4 65 superoxide dismutase 65 P gp 65 germline mutations 65 ncRNA 65 Bacteroides 65 N glycan 65 IL #R 65 LRAT 65 p# NTR 65 Vpu 65 Confocal microscopy 65 C3 convertase 65 proline rich 65 RANTES 65 microRNA expression 65 DGGE 65 CHD5 65 TGF alpha 65 immunoglobulin genes 65 MTHFR gene 65 NKG2D 65 eNOS 65 chromosome condensation 65 cytosolic 65 p# mitogen activated 65 gp# [002] 65 divalent 65 transient transfection 65 SOCS3 65 adducts 65 costimulatory 65 TNFa 65 PDZ domain 65 coding sequences 65 receptor gene 65 EF Tu 65 Annexin V 65 Ca2 + 65 glycoproteins 65 esterase 65 proteases 65 TrkA 65 STAT1 65 LIS1 65 phagocytic cells 65 carboxylate 65 matrix metalloproteinase 65 selective inhibition 65 pro angiogenic 65 disulfide bond 65 lytic 65 HCV replicon 65 regulated kinase ERK 65 beta tubulin 65 acetylation 65 cofactors 65 db db mice 65 glucose transporter 65 recombinase 65 Fig. 3b 65 TERT 65 tetramers 65 FKBP# 65 H2AX 65 glioma cells 65 moieties 65 proteinase 65 adhesion molecule 65 bispecific 65 cyclic peptide 65 Catenin 65 β2 65 c KIT 65 osteogenic 65 glycogen synthase 65 FSH receptor 65 palmitate 65 amine oxidase 65 USP# 65 PPARg 65 CCR9 65 MALAT1 65 quasispecies 65 MLH1 65 AMACR 65 NS5B 65 Anticalins ® 65 BCL2 65 polyadenylation 65 hydrolase 65 cytoskeletal structure 65 HLA B# 65 intronic 65 inhibitory effects 65 nicotinic receptor 65 BMP4 65 single stranded oligonucleotides 65 actinin 65 cardiolipin 65 isotype 65 stem cell pluripotency 65 TRAF6 65 Kv#.# 65 alpha subunit 65 metalloproteases 65 keratinocyte 65 glycosylase 65 cytidine 65 proteins encoded 65 Aβ 65 histone H4 65 MEFs 65 LRP6 65 centromeres 65 epithelial tissues 65 metalloproteinase 65 RNA polymerases 65 angiotensinogen 65 plastid 65 ultrastructural 65 4E BP1 65 enzyme cytochrome 65 ORFs 65 IFN g 65 porphyrin 65 DNA glycosylase 65 eotaxin 65 nucleosides 65 E. faecalis 65 PTEN gene 65 Secretase 65 receptor CD# 65 fibulin 65 supernatants 65 CD# CD# 65 erythrocytes 65 metabolomic profiles 65 prion proteins 65 mutant proteins 65 TGF b 65 receptor gamma 65 cis regulatory 65 Foxp3 65 lysate 65 T#R# 65 monocyte 65 Rac1 65 sialic acids 65 FGF2 65 glycan 65 #S rDNA 65 TNF α 65 cell lysate 65 cytoplasmic tail 65 CYP#C# [002] 65 dynamin 65 immunostaining 65 Huntingtin 65 striated muscle 65 Clusterin 65 HDACs 65 NKX#.# 65 folate receptor 65 adenylate cyclase 65 Rho GTPases 65 TNFR 65 TGF β1 65 neuroligins 65 Protein Kinase C 65 differentially expressed genes 65 autophagic 65 MyoD 65 hypermethylation 65 MMP9 65 Oncogenic 65 prostaglandin E 65 ubiquitin ligase 65 dependent protein kinase 65 glutamyl 65 cell adhesion molecules 65 SGK1 65 PON1 65 CRISPR 65 synthase 65 splice junctions 65 transcriptional activity 65 proteolytic enzymes 65 IGFBP2 65 HIF 1a 65 hepatocyte 65 caveolin 65 constitutively activated 65 Wnts 65 fig. S6 65 κ 65 binding affinity 65 AhR 65 HER2 receptor 65 forkhead 65 SOD1 65 downregulated 65 polymerases 65 S1P 65 diffusible 65 HCV replication 65 COOH terminal 65 causative genes 65 acyltransferase 65 gene loci 65 CD# expression [001] 65 PDE1 65 beta lactamases 65 occludin 65 calcineurin 65 p# mutations 65 exon 65 pharmacodynamic biomarkers 65 β 65 NF1 gene 65 noncoding RNAs 65 #HT#A 65 non coding RNA 65 endothelial nitric oxide synthase 65 norepinephrine reuptake inhibition 64 Rab# 64 iNOS 64 IL 1ß 64 μ opioid receptor 64 chromosomal rearrangement 64 APOBEC3G 64 ERK activation 64 dsRNA 64 SMAD4 64 ß catenin 64 Runx2 64 protein tyrosine kinase 64 glutamate receptor 64 PKC isoforms 64 meiotic recombination 64 ERalpha 64 oncoprotein 64 #S rRNA 64 stromal cells 64 operons 64 TIMP 64 RNA transcripts 64 cyclin E 64 Jhdm2a 64 TIMP 1 64 ribosomal RNA 64 Kinesin 64 telomere dysfunction 64 K ras mutations 64 CD#c 64 Dpp 64 heterochromatic 64 Fig. 2a 64 inhibitory receptor 64 IL #p# 64 cellular prion protein 64 PKM2 64 flavin 64 B7 H4 64 mammalian tissues 64 dehydrogenase 64 RhoA 64 aminopeptidase 64 phenotypic variation 64 biosynthetic pathways 64 myofibroblasts 64 differential gene expression 64 hypoxia inducible factor 64 estrogen receptor alpha 64 coactivators 64 carboxy terminal 64 alveolar epithelial cells 64 polypeptide 64 synaptogenesis 64 modulatory 64 K + ATPase 64 valine 64 retinoid X 64 globin genes 64 ubiquinol 64 Dystrophin 64 intracellular pH 64 cysteine 64 adenoviral 64 thymocyte 64 pyrophosphate 64 Lp PLA 2 64 beta globin gene 64 bone morphogenetic proteins 64 orthologous 64 ectopic expression 64 hypervariable 64 Macrophage 64 desaturase 64 CD# expression [002] 64 adipocyte 64 oncogenic transformation 64 conformational changes 64 HMG CoA reductase 64 demethylase 64 inhibitory activity 64 cyclic AMP cAMP 64 extracellular domains 64 PIP2 64 glial 64 rs# [004] 64 fig. S4 64 mutated protein 64 glucokinase 64 anti CD3 64 excision repair 64 fig. S# 64 VSV G 64 ligand receptor 64 OCT4 64 A. thaliana 64 MDM2 64 antibody antigen 64 Sgk1 64 mutational status 64 beta1 integrin 64 galectins 64 nucleotide substitutions 64 untranslated regions 64 disulfide bonds 64 phosphate S1P 64 sphingomyelin 64 cytochrome P#s 64 protein kinases 64 Vpr 64 redox active 64 downregulation 64 intermediate filaments 64 PAX5 64 ubiquitin ligases 64 RAS RAF MEK 64 adipokines 64 oxidase 64 Kir#.# 64 Golgi apparatus 64 transporter proteins 64 peptidase 64 bronchial epithelial cells 64 inactivating mutations 64 intergenic regions 64 transient receptor 64 serum antibodies 64 HLA molecules 64 Aâ 64 oncoproteins 64 MIF protein 64 cofilin 64 allelic 64 H#K# [002] 64 IL6 64 dehydrogenases 64 indel 64 unmethylated 64 bone morphogenetic protein 64 glutathione S transferase 64 trimeric 64 DNA methylation patterns 64 PHD2 64 FGFR4 64 agonism 64 humoral responses 64 renal fibrosis 64 PrPSc 64 amyloid fibrils 64 Sox2 64 peripheral blood mononuclear 64 MAPK 64 somatostatin 64 intracellular signaling 64 viral proteins 64 epithelial barrier 64 cadherins 64 DGAT1 64 intercellular signaling 64 secreted protein 64 M. pneumoniae 64 budding yeast 64 Akt1 64 basolateral 64 gene amplification 64 cytoprotective 64 NR2B subunit 64 conserved sequences 64 ABCA1 64 TGF ß1 64 mutational analysis 64 TRIM5 64 oligosaccharides 64 Fig. 3A 64 homologous 64 enzymatic reactions 64 PU.1 64 UTRs 64 Notch signaling 64 NSCLC tumors 64 fibronectin 64 T#I [002] 64 ganglioside 64 #ß 64 homeobox gene 64 costimulation 64 adenoviral vector 64 multiprotein complex 64 BMP receptor 64 kallikrein 64 SH2 domain 64 transcriptional machinery 64 bile acid 64 cytochrome c 64 perilipin 64 Cdc# 64 Fig. 2b 64 IKK 64 cathepsins 64 cysteine protease 64 Syt II 64 stereochemistry 64 thrombin receptor 64 intracellular bacteria 64 intracellularly 64 catalase 64 C EBP 64 lectins 64 Src 64 TXNIP 64 transcriptionally 64 biochemical assays 64 phenotypes 64 ligase 64 phenotypic expression 64 Nanog 64 MyD# 64 microRNA miR 64 plasmacytoid dendritic cells 64 thyroid hormone receptor 64 glycolytic 64 transmembrane domain 64 ESR1 64 polyglutamine 64 5alpha reductase 64 microtubule associated 64 FOXO3a 64 Polymorphisms 64 proximal tubular 64 innate immune responses 64 HbF 64 muscarinic receptors 64 eIF2 64 titin 64 procaspase 3 64 serotonin receptor 64 CCL# 64 IL 1beta 64 anaphase promoting complex