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(Click for frequent words.) 76 neuronal 73 synapse 72 synapses 69 neurons 69 neuron 67 neural 67 synaptic plasticity 66 neuronal activity 66 postsynaptic 66 hippocampal 66 NMDA receptors 66 cortical 65 striatal 65 presynaptic 65 NMDA receptor 64 plasticity 64 glial 64 nerve cells 64 synaptogenesis 64 synaptic transmission 64 anterior cingulate 64 neurones 64 inhibitory 64 dopaminergic 64 glutamate 63 BMP signaling 63 serotonergic 63 neuromuscular junction 63 synaptic connections 63 dendritic spines 63 cortex 63 hypothalamic 63 dopamine signaling 63 intracellular 63 dopamine 62 synapse formation 62 excitatory 62 neuronal synapses 62 neurochemical 62 forebrain 62 neurotransmitter 62 axonal 62 neurotransmission 62 hippocampal neurons 62 BDNF 62 cytoskeletal 62 synaptic cleft 62 dendrite 62 midbrain 62 Wnt signaling 61 neuronal plasticity 61 neuronal signaling 61 myelination 61 hypocretin neurons 61 ACh 61 cortical neurons 61 neurone 61 modulatory 61 glutamatergic 61 neurogenesis 61 hindbrain 61 basal ganglia 61 neuronal circuits 60 Purkinje cells 60 neuronal connections 60 dopaminergic neurons 60 inhibitory interneurons 60 AMPA receptors 60 cerebellum 60 glutamate receptors 60 exocytosis 60 limbic 60 pyramidal neurons 60 cilium 60 cholinergic 60 PKMzeta 60 Rac1 60 dopamine receptors 60 neuronal dysfunction 60 extracellular 60 paxillin 60 neural circuits 60 dentate gyrus 60 cerebellar 60 synapse maturation 60 somatosensory cortex 60 neurotransmitter glutamate 60 visual cortex 59 Purkinje cell 59 synaptic vesicles 59 HPA axis 59 tau protein 59 term potentiation 59 centrosome 59 neurotransmitters 59 MEF2 59 TrkB 59 dopamine transporter 59 intercellular 59 transcriptional regulation 59 dendritic 59 calpain 59 mPFC 59 cytosol 59 neuronal cells 59 granule cells 59 proteolysis 59 Cdc# 59 mesolimbic 59 serotonin 59 adult neurogenesis 59 AMPA receptor 59 serotonergic neurons 59 neuronal degeneration 59 NR2B 58 neural pathways 58 Ca2 + 58 focal adhesions 58 excitatory synapses 58 interneurons 58 striatum 58 POMC neurons 58 DISC1 58 actin cytoskeleton 58 astrocyte 58 autophagic 58 synaptic function 58 microtubule 58 axonal transport 58 Aβ 58 neuroligin 58 conformational 58 microglial 58 D2 receptor 58 neural pathway 58 noradrenergic 58 dorsal horn 58 adherens junctions 58 GABAA receptors 58 opioid receptor 58 dopamine neurons 58 cAMP 58 medial prefrontal 58 acetylcholine 58 endoplasmic reticulum 58 Wnt pathway 58 focal adhesion 57 glutamate transporters 57 neurotransmitter dopamine 57 centrosomes 57 nAChR 57 hippocampus 57 amyloid β 57 thalamic 57 monoamine 57 brain circuitry 57 intramolecular 57 cortico 57 Fig. 1C 57 cortical regions 57 axon 57 connexin# 57 efferent 57 caspase activation 57 cypin 57 intracellular calcium 57 inhibitory synapses 57 cyclic AMP 57 homeostatic 57 calcium homeostasis 57 ABCA1 57 melanocyte 57 GABAergic interneurons 57 cingulate 57 PIP2 57 neuronal migration 57 excitation contraction 57 D2 receptors 57 microtubules 57 dorsolateral 57 afferent 57 MeCP2 57 membrane protein 57 intracellular signaling 57 glutamate receptor 57 synaptic proteins 57 glial cell 57 NAc 57 Sonic hedgehog 57 neuronal differentiation 57 leptin signaling 57 rostral 57 SOCS3 57 F actin 57 dendritic spine 57 mutant protein 57 catecholamine 57 GABAergic 56 endothelial 56 GluR1 56 E cadherin 56 hypothalamic pituitary adrenal axis 56 neuronal pathways 56 adhesion molecule 56 mitochondrial respiration 56 BMAL1 56 primary visual cortex 56 receptor activation 56 neural cells 56 ATPase 56 oligodendrocyte 56 palmitoylation 56 GABAB receptors 56 autocrine 56 Notch1 56 premotor 56 NKT cell 56 CaMKII 56 estrogen receptor alpha 56 calmodulin 56 NR2B subunit 56 acetylcholine neurotransmitter 56 lateral hypothalamus 56 β catenin 56 interconversion 56 inhibitory neurons 56 brain 56 motoneurons 56 electrophysiological 56 mitochondrial membrane 56 neurite outgrowth 56 excitatory neurons 56 acetylcholine receptors 56 neurite 56 excitation 56 retinal neurons 56 Hedgehog signaling 56 NMDAR 56 cadherin 56 plasma membrane 56 MyD# 56 locus coeruleus 56 phosphorylation 56 nociceptive 56 astrocytic 56 serotonin transporter 56 morphogen 56 cAMP signaling 56 glucocorticoid 56 neuronal function 56 chromatin structure 56 transcriptional 56 basolateral 56 tumorigenesis 56 axon guidance 56 hyperactivation 56 mTORC1 56 protein synthesis 56 Htt 56 neocortical 56 corticospinal 56 Smad3 56 neuronal cell 56 caveolae 56 norepinephrine 56 XBP1 56 signaling pathways 56 neurotransmitter receptor 56 inhibitory neurotransmitters 56 gyrus 56 dysregulation 56 somatosensory 56 hormone secretion 56 ERK2 56 Nrf2 56 neuroepithelial cells 56 oligomerization 55 myofibroblasts 55 cellular senescence 55 noradrenaline 55 dopamine receptor 55 serotonin signaling 55 caudate 55 amygdala neurons 55 FMRP 55 Rab5 55 serotonin neurons 55 hypocretin 55 neurotransmitter receptors 55 baroreceptor 55 postsynaptic neuron 55 neurites 55 Golgi apparatus 55 cohesin 55 intercellular communication 55 endoplasmic reticulum ER 55 glutamate signaling 55 motor neuron 55 Sonic Hedgehog 55 oscillatory 55 habenula 55 mirror neuron 55 neuroendocrine 55 neurochemicals 55 muscarinic receptors 55 gamma oscillations 55 skeletal muscle 55 Golgi 55 p# activation 55 GABA neurotransmitter 55 DNMT1 55 paracrine 55 Aß 55 GABA receptor 55 BDNF gene 55 neuropeptides 55 ciliary 55 brainstem 55 neural connections 55 MAP kinase 55 Acetylcholine 55 Skp2 55 abnormal neuronal 55 Hcrt 55 transmembrane 55 paraventricular nucleus 55 endosomes 55 netrin 1 55 chromosome condensation 55 lysosome 55 endocannabinoid system 55 angular gyrus 55 mitochondrial 55 FOXO 55 tyrosine 55 axons 55 GABAA 55 beta catenin 55 MAPK 55 striatal dopamine 55 Aâ 55 beta globin 55 mitotic 55 calcium ion 55 LIS1 55 neural plasticity 55 spectrin 55 actin binding 55 neuroligins 55 tyrosine phosphorylation 55 membrane fusion 55 signaling cascade 55 sensorimotor 55 downregulation 55 transcriptional activation 55 mutant mice 55 cofilin 55 phagocytosis 55 prefrontal cortical 55 signaling molecule 55 ubiquitination 55 posterior cingulate 55 kalirin 55 molecular mechanism 55 RhoA 55 mesoderm 55 cell adhesion 55 neurodegeneration 55 ERK1 2 55 SUMOylation 55 PrP 55 lysosomal 55 spermatogenesis 55 SIRT1 55 beta endorphin 55 Neurons 55 colocalization 55 glutamine 55 apoptotic 55 messenger molecule 55 vagus 55 vesicle 55 CaM kinase II 55 presenilin 54 VE cadherin 54 E3 ubiquitin ligase 54 dynactin 54 contractility 54 posterior cingulate cortex 54 auditory cortex 54 Prox1 54 neurobiological 54 mitochondria 54 Bcl xL 54 autoregulation 54 TXNIP 54 Sgk1 54 mitochondrial proteins 54 serotonin receptor 54 huntingtin 54 monocyte 54 depolarization 54 neuro transmitter 54 H#K# [002] 54 synaptic vesicle 54 podocyte 54 TGF β 54 stathmin 54 potentiation 54 mutant huntingtin protein 54 cortices 54 retinal ganglion cells 54 beta adrenergic receptors 54 thalamus 54 osteoblast 54 CFTR 54 dopamine transporters 54 metabolic pathways 54 myocyte 54 anterior temporal lobe 54 protein tau 54 calcineurin 54 telomeric 54 neurotransmitter acetylcholine 54 c Src 54 acetylcholine receptor 54 SIRT3 54 leptin receptors 54 myogenesis 54 mRNA 54 PINK1 54 vascular endothelial cells 54 β cell 54 Cyclin D1 54 collagen fibers 54 HOTAIR 54 cytosolic 54 nitric oxide synthase 54 TGFβ 54 ubiquitin ligase 54 histone 54 term potentiation LTP 54 IRE1 54 ectopic expression 54 sensory neuron 54 orbital frontal cortex 54 X inactivation 54 contractile 54 gamma aminobutyric acid GABA 54 disulfide bond 54 brain hemispheres 54 excitatory neurotransmitter 54 autophagy 54 neuroanatomical 54 GTPase 54 pRb 54 OPHN1 54 hyperexcitability 54 TRPV1 receptors 54 FoxO1 54 biogenesis 54 secretory 54 neurotransmitter norepinephrine 54 TRPV4 54 toxic beta amyloid 54 amino acid 54 demyelination 54 insulin receptors 54 kinase domain 54 biochemical pathway 54 vacuolar 54 conformational changes 54 vascular endothelial 54 SVZ 54 neuropeptide Y 54 dephosphorylation 54 isoforms 54 plasminogen 54 eNOS 54 mitogen activated protein kinase 54 FGF signaling 54 dystroglycan 54 orexin neurons 54 FGF# 54 glycosylation 54 P cadherin 54 IKKß 54 TFIIH 54 actin 54 tumor suppressor protein 54 hsp# 54 phenotype 54 catabolism 53 afferents 53 proinflammatory 53 dendrites 53 GAPDH 53 Cdk5 53 ubiquitylation 53 hypothalamus 53 cerebral cortex 53 factor BDNF 53 Myosin II 53 Wnt 53 neural mechanisms 53 lipid rafts 53 fronto 53 neurohormonal 53 metabolic 53 transcriptional machinery 53 parietal cortex 53 dimer 53 Smoothened 53 receptor gamma 53 serine threonine kinase 53 FGF2 53 cytoskeleton 53 histone methylation 53 cortical plasticity 53 neurocircuitry 53 prefrontal brain 53 upregulation 53 glia 53 osteoclast 53 mammalian brain 53 hippocampal synapses 53 MALAT1 53 cyclin B1 53 PIP3 53 DLPFC 53 catenin 53 cognition 53 dorsolateral prefrontal cortex 53 secretase 53 auxin 53 Runx2 53 depolarizing 53 circadian clock genes 53 CatB 53 MEF2D 53 parasympathetic 53 thyroid hormones 53 oligomers 53 Rev erb 53 signaling pathway 53 EGFR signaling 53 inferior frontal 53 rostral anterior cingulate cortex 53 molecular pathway 53 occludin 53 induced neuronal 53 SGK1 53 CaM 53 prefrontal lobe 53 TGF beta 53 remyelination 53 midbrain dopamine neurons 53 ENaC 53 Notch signaling 53 podocytes 53 BACE1 53 LKB1 53 regulated kinase ERK 53 NFAT 53 dorsal anterior cingulate cortex 53 Brain derived neurotrophic 53 orbitofrontal cortex OFC 53 excitotoxic 53 hippocampal function 53 ventral prefrontal cortex 53 dopamine norepinephrine 53 embryogenesis 53 hypothalamic neurons 53 glucocorticoid receptors 53 mRNA expression 53 HtrA2 53 medulla 53 costimulatory 53 Kv#.# 53 neural crest cells 53 S#K# 53 mTOR signaling 53 astrocytes 53 attentional 53 centromeres 53 Dysregulation 53 rACC 53 Rap1 53 cortical activation 53 genotoxic stress 53 fatty acid oxidation 53 cortexes 53 miR# 53 ligand binding 53 glia cells 53 nicotinic receptors 53 CEACAM1 53 transmembrane protein 53 noradrenalin 53 PPAR gamma 53 superior colliculus 53 physiologic 53 amygdala 53 dopamine serotonin 53 Notch pathway 53 amygdalae 53 MAPKs 53 arcuate nucleus 53 kisspeptin 53 meiotic 53 Glutamate 53 oxidative phosphorylation 53 prefrontal cortex 53 enteric nervous 53 extracellular signal 53 Dopamine 53 progranulin 53 MT1 MMP 53 endothelial cell 53 homodimers 53 TGF ß 53 brain cortex 53 cysteine 53 perivascular 53 pDCs 53 neurotransmitter serotonin 53 Shh signaling 53 GLUT4 53 nNOS 53 c Fos 53 dopamine neurotransmitter 53 Sirt1 53 endogenous 53 EZH2 53 tau aggregates 53 ephrin 53 hemichannels 53 amyloid deposits 53 tau 53 desmosomes 53 adenosine 53 histone acetylation 53 endocytic 53 UCP2 53 intracellular signal transduction 53 RUNX3 53 Abeta 53 ligand receptor 53 rhodopsin 53 Fig. 1A 53 heterochromatic 53 TRPV1 53 nigrostriatal 52 phasic 52 neural circuitry 52 serine 52 GABAergic neurons 52 KLF# 52 entorhinal cortex 52 Neuronal 52 dopaminergic neuron 52 clathrin 52 anterior pituitary 52 mutant proteins 52 circadian pacemaker 52 ion channels 52 uncharacterized genes 52 polypeptide 52 ligand 52 nAChRs 52 #BP# 52 NF kB signaling 52 receptor subtypes 52 amyloid deposition 52 inhibitory neurotransmitter 52 epigenetic silencing 52 enzymatic activity 52 neuroblasts 52 serotonin transporters 52 brain limbic 52 neurosteroids 52 subcellular 52 neuroprotection 52 dynein 52 intestinal epithelium 52 DARPP 52 proprioceptive 52 transactivation 52 protein kinase 52 motor neurons 52 posterior parietal cortex 52 ontogeny 52 inducible 52 transcriptionally 52 β 52 neurophysiological 52 leptin 52 peroxisome 52 excitotoxicity 52 inhibitory transmitter 52 primary cilium 52 theta oscillations 52 alpha synuclein 52 Pax6 52 androgen receptor 52 mitochondrial dysfunction 52 huntingtin protein 52 trigeminal 52 inferior parietal 52 integrin 52 tau proteins 52 glycan 52 magnetization 52 endocytosis 52 molecular pathways 52 mitotic spindle 52 myosin 52 SIRT1 gene 52 centromere 52 transgenic mice expressing 52 excitatory neurotransmitter glutamate 52 lysosomes 52 primary cilia 52 circadian 52 beta subunit 52 PML RARA 52 myocardial tissue 52 voltage gated 52 heterochromatin 52 osteocalcin 52 γ 52 p#NTR 52 polyglutamine 52 TRPV3 52 neurochemistry 52 PTEN protein 52 neuronal membranes 52 intron 52 semaphorin 52 amyloid precursor protein 52 lipid metabolism 52 secretory pathway 52 receptors 52 dopamine neuron 52 anaphase 52 actin polymerization 52 parietal cortices 52 gluconeogenesis 52 5 HT1A 52 kinase pathway 52 endocannabinoid 52 morphogenesis 52 chromatin 52 mice lacking 52 medial frontal cortex 52 inflammatory cytokine 52 rat hippocampus 52 mutant huntingtin 52 ventromedial 52 MDSCs 52 ERK signaling 52 neurotrophin 52 organelle 52 cytoskeletal protein 52 FAK 52 microglial activation 52 BMP4 52 posteromedial cortex 52 perirhinal cortex 52 NAcc 52 glucocorticoid receptor 52 receptor mediated 52 ERK pathway 52 MAPK pathway 52 cardiomyocyte 52 neuro transmitters 52 neural substrates 52 organogenesis 52 aldosterone 52 thermoregulatory 52 tRNA 52 protein kinase C 52 epithelial 52 Pten 52 endogenous cannabinoids 52 amyloid beta plaques 52 TAp# 52 p# pathway 52 cardiac fibroblasts 52 p#/CBP 52 corticosterone 52 adenosine receptors 52 electroencephalographic 52 mu opioid receptors 52 nerve fibers 52 innervation 52 melatonin receptors 52 γ secretase 52 vagal 52 medial prefrontal cortex 52 neurosteroid 52 ghrelin 52 glucose transporter 52 beta arrestin 52 CXCL# 52 phosphorylated 52 metabolic enzymes 52 evolutionarily conserved 52 adrenergic 52 premotor cortex 52 cell motility 52 Hh 52 ribozyme 52 vivo 52 D aspartate 52 theta waves 52 glucose metabolism 52 sensory nerves 52 Jhdm2a 52 renal fibrosis 52 agonist induced 52 actin filaments 52 protein conformation 52 phosphorylates 52 immunological 52 orbitofrontal cortex 52 HSF1 52 neuropeptide 52 temporoparietal junction 52 neuropeptide Y NPY 52 E1A 52 suprachiasmatic nucleus 52 gamma secretase 52 phospholipid 52 calcium ions 52 subthalamic nucleus 52 antioxidant enzyme 52 intracellular proteins 52 alpha subunit 52 overactivation 52 brain neurochemistry 52 c Myb 52 ventral pallidum 52 transduction 52 dynamin 52 TGF beta pathway 52 medial temporal 52 GRK2 52 limbic system 52 mirror neuron system 52 ouabain 52 dysregulated 52 insulin secretion 52 cytochrome 51 nerve axons 51 cofactor 51 serotonin receptors 51 histone modifications 51 progerin 51 interneuron 51 receptor 51 cyclic AMP cAMP 51 opioid receptors 51 osteoblast differentiation 51 cardiac myocytes 51 transcriptional regulators 51 SAP# 51 subcortical 51 amyloid peptides 51 c Myc 51 vasopressin 51 insular cortex 51 PTPN# 51 apoptosis pathway 51 intermolecular 51 myelinated axons 51 TSLP 51 cholesterol efflux 51 kinetochore 51 receptor subtype 51 noncoding RNA 51 TRAF6 51 anti apoptotic 51 mutated protein 51 mammalian 51 ß1 51 p#Kip# 51 knockout mice 51 sensory neurons 51 mRNA translation 51 myofibroblast 51 downregulate 51 temporal lobe 51 chromatin remodeling 51 Akt 51 deficient mice 51 CTCF 51 proteins 51 induced apoptosis 51 cortical excitability 51 telomeric DNA 51 brain derived neurotrophic 51 Hox gene 51 mechanotransduction 51 palytoxin 51 neural crest 51 neurotrophins 51 periaqueductal gray 51 PGE2 51 sensory cortex 51 c myc 51 drug metabolizing enzymes 51 p# [001] 51 γδ T cells 51 hippocampal cells 51 mRNAs 51 GPR# [002] 51 mitochondrial function 51 immunoreactivity 51 radial glia 51 stereocilia 51 overexpression 51 Lyn kinase 51 cellular pathways 51 CB1 receptor 51 signaling molecules 51 tumor suppressor gene 51 researchers hypothesize 51 myocytes 51 5' triphosphate 51 myosin II 51 CD1d 51 p# protein 51 molecular mechanisms underlying 51 S#A# [002] 51 brain neurotransmitter 51 epithelia 51 neurofibromin 51 parietal 51 BDNF protein 51 cellular signaling pathways 51 cadherins 51 autonomic nervous system 51 CHD5 51 oncoprotein 51 NAD + 51 transcriptional repressor 51 TGF b 51 beta1 integrin 51 CB1 receptors 51 anterograde 51 epithelial cell 51 biosynthesis 51 ß amyloid 51 ligase 51 myocardial 51 neuronal excitability 51 centrioles 51 fusiform 51 tubulin 51 amyloid protein 51 serine protease 51 insulin secreting cells 51 microtubule dynamics 51 apical 51 superoxide dismutase 51 glutamate neurotransmitter 51 oculomotor 51 ß catenin 51 photoreceptor 51 alpha secretase 51 potassium ion 51 diffusible 51 humoral 51 ceramide 51 cortical circuits 51 dorsolateral prefrontal 51 orexin 51 STAT3 51 supramolecular 51 cytochrome c oxidase 51 SLC#A# [002] 51 auditory 51 tropomyosin 51 parahippocampal gyrus 51 cdk5 51 allopregnanolone 51 morphogens 51 frontal parietal 51 cell adhesion molecules 51 visuomotor 51 TGFß 51 hippocampi 51 CDH# 51 JAK STAT 51 putamen 51 cytokinesis 51 tumor suppressor p# 51 Ago2