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(Click for frequent words.) 78 tumor suppressor gene 74 p# [001] 74 NF kB 74 STAT3 73 SIRT1 73 tumorigenesis 73 Src 72 androgen receptor 72 tumor suppressor genes 71 signaling pathway 71 Akt 71 oncogenes 71 tumor suppressor protein 71 TGF beta 70 EZH2 70 oncogenic 70 protein kinase 70 Wnt pathway 70 oncoprotein 70 beta catenin 70 gamma secretase 70 tumor suppressors 70 p# gene 70 c Myc 70 signaling molecule 70 oncogene 69 transcription factor 69 p# protein 69 mTOR 69 PP2A 69 estrogen receptor 69 overexpression 69 cyclin D1 69 Skp2 69 proto oncogene 69 tumor angiogenesis 69 MDM2 69 Myc 69 retinoblastoma protein 68 NF κB 68 Cdc# 68 SGK1 68 S1P 68 protein p# 68 kinase 68 Notch signaling 68 molecular pathway 68 E#F# 68 pRb 68 ubiquitination 67 Stat3 67 transcription factors 67 PI3K pathway 67 E cadherin 67 caspase 67 FOXO3a 67 MAPK 67 Nrf2 67 uPAR 67 gene p# 67 ubiquitylation 67 catenin 67 EGFR 67 phosphorylation 67 cell signaling pathway 67 TGF β 67 MAPK pathway 67 proteases 67 histone deacetylases 67 SIRT6 67 calpain 67 PGE2 67 Pin1 66 VEGF receptor 66 NFkB 66 Hedgehog pathway 66 p# tumor suppressor 66 integrin 66 mitogen activated protein kinase 66 EGF receptor 66 c MYC 66 Notch1 66 Hedgehog signaling 66 c myc 66 Mcl 1 66 tyrosine kinase 66 E1A 66 SOD1 66 COX2 66 RUNX3 66 Smad3 66 DISC1 66 cell motility 66 Akt1 66 PI3K 66 RANKL 66 micro RNAs 66 miR 66 TAp# 66 LKB1 66 kinases 66 miRNAs 66 JAK2 66 Wnt 66 PI3 kinase 66 microRNAs 65 phosphatidylinositol 3 65 PTEN gene 65 apoE 65 Aβ 65 NF kappaB 65 NMDA receptor 65 phosphorylates 65 phosphorylate 65 Phosphorylation 65 neurofibromin 65 Wnt signaling 65 estrogen receptors 65 CTLA 4 65 EGFR signaling 65 GSK 3ß 65 NKX#.# 65 HDACs 65 RNA splicing 65 Foxp3 65 mutant protein 65 progerin 65 TGF ß 65 FANCD2 65 HDAC 65 IGF 1R 65 LRP6 65 chemokine receptor 65 protein kinases 65 mTORC1 65 SIRT3 65 Th# cells 65 MAP kinase 65 EphA2 65 E3 ligase 65 evolutionarily conserved 65 ubiquitin ligase 65 tyrosine kinases 65 PTP1B 65 tumor suppressor proteins 65 ER alpha 65 Smoothened 65 receptor tyrosine kinase 65 melanocyte 65 CHD5 65 PAK1 65 Rac1 65 Wnt signaling pathway 65 UCP2 65 Caspase 65 KLF# 64 presenilin 64 protein kinase C 64 Pten 64 regulating gene expression 64 IGFBP2 64 IDH1 64 cell signaling pathways 64 glucocorticoid receptor 64 signaling pathways 64 enzyme 64 Cdk5 64 B Raf 64 PPAR alpha 64 adhesion molecule 64 STAT1 64 BCR ABL 64 clusterin 64 AMPK 64 cyclins 64 kinase pathway 64 potent inhibitor 64 enzymatic activity 64 SIRT2 64 MeCP2 64 MDMX 64 phosphorylated 64 autophagy 64 molecular pathways 64 eNOS 64 ERK1 2 64 NFκB 64 IKKß 64 phosphatases 64 mTOR pathway 64 neuroblastoma cells 64 caspases 64 FOXO1 64 serine threonine kinase 64 hypermethylation 64 induces apoptosis 64 VEGF 63 Nedd4 63 serine protease 63 extracellular signal 63 Notch pathway 63 RANK ligand 63 cyclin dependent kinase 63 caveolin 1 63 HGF 63 Rad# 63 Hedgehog signaling pathway 63 FoxO1 63 cyclooxygenase 63 receptor protein 63 phosphatase 63 tumor suppressive 63 ADAM# 63 hedgehog pathway 63 glutamate receptors 63 WT1 63 microRNA miR 63 selective inhibition 63 PTEN 63 FGF# 63 GATA3 63 Galectin 63 metalloprotease 63 transcriptional repressor 63 NKT cells 63 activin 63 isoform 63 Jagged1 63 suppressor gene 63 GTPase 63 GSK3 63 serotonin receptor 63 SH2 B 63 Stat5 63 gene transcription 63 TGFβ 63 XBP1 63 casein kinase 63 Apoptosis 63 BCL2 63 PDGFR 63 PPAR gamma 63 TORC2 63 IKKa 63 Rap1 63 HER3 63 Smurf1 63 FAK 63 molecular mechanism 63 androgen receptor AR 63 cadherin 63 S#K# 63 homeobox gene 63 transactivation 63 iNOS 63 hypoxia inducible factor 63 ErbB2 63 caveolin 63 regulated kinase ERK 63 receptor molecule 63 ACE2 63 SATB1 63 SREBP 63 cell adhesion molecule 63 calcineurin 63 FGFR3 63 PTEN protein 63 Bcl 2 63 protein synthesis 63 Dicer 63 c MET 63 Upregulation 63 c Abl 63 Lyn kinase 63 CatB 63 peroxisome proliferator activated 63 Cyclin D1 63 NFAT 62 DNMT1 62 TNFα 62 intracellular signaling 62 PCSK9 62 miR #a [002] 62 aromatase 62 upregulation 62 cyclin dependent kinases 62 cytokine 62 encodes protein 62 Syk 62 RNA silencing 62 IRF5 62 TMEM#B 62 lysosomal 62 myostatin 62 coactivator 62 cellular metabolism 62 BMP4 62 p#/CBP 62 tumor suppressor p# 62 tumor suppressing 62 MUC1 62 β catenin 62 Kinase 62 HIF 1alpha 62 cAMP 62 GLI1 62 gene encoding 62 neurotrophin 62 sirtuin 62 TGF b 62 poly ADP ribose polymerase 62 tyrosine phosphorylation 62 cystic fibrosis transmembrane conductance 62 podocyte 62 DLX5 62 CDK4 62 CXCL# 62 IRAK1 62 NF kappa B 62 LRP5 62 chemokine 62 factor receptor 62 acetylation 62 GRK2 62 phosphate S1P 62 cyclin dependent kinase inhibitor 62 cyclin 62 Sir2 62 transmembrane protein 62 Rho GTPase 62 H#K# [002] 62 mutated protein 62 apoptosis 62 ErbB3 62 ERK pathway 62 SOD1 protein 62 estrogen receptor alpha 62 Mdm2 62 thioredoxin 62 cyclin E 62 regulate gene expression 62 PKM2 62 SMN1 62 TGF beta pathway 62 Bcl xL 62 paxillin 62 mTOR signaling 62 JAK STAT 62 IGF1 62 ERK 62 LDL receptor 62 NRG1 62 5 lipoxygenase 62 protein encoded 62 HOTAIR 62 tau protein 62 angiogenesis 62 PKD1 62 E3 ubiquitin ligase 62 γ secretase 62 HDAC inhibitors 62 p# pathway 62 p# MAPK 62 proteins 62 Akt3 62 ß catenin 62 methylation 62 MicroRNA 62 LRRK2 62 cytoskeletal 62 vimentin 62 transmembrane receptor 62 Methylation 62 huntingtin 62 matrix metalloproteinase 62 breast cancer metastasis 62 Hypoxia Inducible Factor 62 PPARγ 62 actin cytoskeleton 62 hedgehog signaling 62 Protein Kinase 62 genomic instability 62 Argonaute 61 Wnt#b 61 PGC 1alpha 61 LIS1 61 inhibits tumor 61 overexpressing 61 GNAQ 61 ERK2 61 CTGF 61 GTPases 61 microRNAs miRNAs 61 palladin 61 survivin 61 Bcr Abl 61 selective inhibitor 61 RhoA 61 Dystrophin 61 gastrin 61 NMDA receptors 61 Smad7 61 neurite outgrowth 61 FOXP3 61 proteolysis 61 utrophin 61 glucokinase 61 integrins 61 ABCA1 61 C EBP alpha 61 SIRT1 gene 61 PAR1 61 cofilin 61 Notch receptor 61 apoptotic pathway 61 BACE1 61 cellular senescence 61 Overexpression 61 Frizzled 61 ERK signaling 61 phagocytosis 61 Six3 61 TGF Beta 61 biochemical pathway 61 receptor 61 Kv#.# 61 tetherin 61 aldose reductase 61 gene 61 micro RNA 61 FGFR1 61 synapse formation 61 transcriptional regulation 61 miRNA 61 NF kB pathway 61 neurogenesis 61 KLF4 61 inhibit tumor 61 Cdc7 61 pro apoptotic 61 EGFRvIII 61 KLF2 61 Sp1 61 metabolic enzymes 61 PARP 61 HDAC6 61 ErbB4 61 primary cilia 61 chromatin remodeling 61 transcriptional activation 61 proteasome 61 TCF#L# 61 p#INK#a 61 OCT4 61 synaptogenesis 61 IL 1β 61 HSF1 61 Akt activation 61 Rb#/p# 61 RAR beta 61 laminin 61 glycogen synthase kinase 61 E cadherin expression 61 regulates gene expression 61 molecule epidermal 61 GAPDH 61 BCL6 61 estrogen receptor beta 61 ras gene 61 RNAs 61 pro angiogenic 61 tubulin 61 tumor vasculature 61 VE cadherin 61 overexpress 61 epigenetic silencing 61 SUMOylation 61 macrophage 61 renal fibrosis 61 Klf4 61 MMPs 61 fusion protein 61 genes encoding 61 FOXO 61 protein 61 beta subunit 61 NOD2 61 MSH2 61 syntaxin 61 neurexin 61 apoptotic 61 angiogenic 61 dynamin 61 Abl 61 alpha synuclein 61 antitumor 60 isoforms 60 receptor subtype 60 anti apoptotic 60 immunoregulatory 60 AMPA receptor 60 beta amyloid peptide 60 inhibitory 60 telomerase reverse transcriptase 60 ubiquitinated 60 secreted protein 60 deacetylation 60 protease 60 histone 60 thyroid hormone receptor 60 IL 1beta 60 sortilin 60 tumor cells 60 FGFR2 60 CXCR4 60 RANK Ligand 60 PTPN# 60 synuclein 60 endothelial nitric oxide synthase 60 MEK1 60 CaM kinase II 60 autocrine 60 cytochrome P# 60 PPARg 60 Her-2/neu 60 HMG CoA reductase 60 induce apoptosis 60 ubiquitin ligases 60 MDSCs 60 FGFR4 60 TSC1 60 retinoic acid 60 superoxide dismutase 60 ARF1 60 overexpressed 60 lipoxygenase 60 neural crest 60 PALB2 60 cathepsins 60 ALDH2 60 biogenesis 60 EGFr 60 mRNA 60 neuromuscular junction 60 Vpr 60 Plk1 60 MALAT1 60 ligase 60 ATPase 60 FGFs 60 Rho kinase 60 BMP signaling 60 Eg5 60 MyoD 60 nNOS 60 adipogenesis 60 suppresses tumor 60 mitogen activated protein 60 HBx 60 ENaC 60 glioma cells 60 glial cell 60 Bcl XL 60 ATF2 60 MMP9 60 myogenesis 60 arginase 60 autophagic 60 Sirt1 60 DICER1 60 Yap1 60 CK2 60 naturally occurring molecule 60 RIP1 60 microRNA 60 virulence genes 60 GPR# [002] 60 ERK1 60 catalase 60 RAS RAF MEK 60 Factor Receptor 60 4E BP1 60 splice variant 60 ligases 60 NR2B 60 ERa 60 p# activation 60 tyrosine kinase receptor 60 fatty acid synthase 60 TSLP 60 protein fragment 60 Oct4 60 Runx2 60 RNA polymerase II 60 demethylase 60 glutamate receptor 60 CD# [002] 60 HDAC2 60 CCR2 60 CD#L 60 NKX2 60 E2F 60 POMC neurons 60 RSK2 60 chaperone protein 60 USP# 60 PIP2 60 NOTCH1 60 PRDM# 60 cofactor 60 VEGFR1 60 protein CETP 60 transgenic mouse model 60 TERT 60 LRP1 60 MAP kinase pathway 60 NF kappaB pathway 60 nicotinic receptors 60 aberrantly activated 60 antioxidant enzyme 60 protein misfolding 60 progranulin 60 Aß 60 monocyte 60 H#K# [001] 60 #beta HSD1 60 plasma kallikrein 60 heme oxygenase 60 CYP# [002] 60 MEK ERK 60 cellular pathways 60 TRAF6 60 Smad 60 downregulation 60 CD# protein 60 mitochondrial 60 Vpu 60 cyclooxygenase 2 60 messenger molecule 60 Bcl2 60 H#K# methylation 60 TORC1 60 Nurr1 60 DLC1 60 insulin receptors 60 osteocalcin 60 Rab# 60 oncogenic transformation 60 activating mutations 60 HER2 receptor 60 homolog 60 glycoprotein 60 small molecule inhibitors 60 VEGFR 59 osteopontin 59 NFkappaB 59 MEF2 59 PPARgamma 59 ncRNAs 59 alternatively spliced 59 neuronal cell 59 CD# receptor 59 GM CSF 59 VHL gene 59 MnSOD 59 MyD# 59 miRNA genes 59 B7 H1 59 Akt signaling 59 S#A# [002] 59 apoE4 59 FKBP# 59 CIB1 59 costimulatory 59 metastasis 59 proapoptotic 59 glycosyltransferase 59 forkhead 59 TLR2 59 carcinogenesis 59 neuropeptide Y NPY 59 Rab5 59 Htt 59 ERBB4 59 Pdx1 59 sirtuins 59 FLT3 59 brain derived neurotrophic 59 alpha synuclein gene 59 focal adhesion kinase 59 CPEB 59 downstream effectors 59 dysregulated 59 FUS1 59 SH#B# 59 subunit 59 Prox1 59 PIK3CA 59 naturally occurring protein 59 Hh pathway 59 telomere maintenance 59 Olig2 59 selective inhibitors 59 STAT4 59 IKK 59 N Myc 59 Raf MEK ERK 59 centrosome 59 Flt3 59 p# MAP kinase 59 eotaxin 59 constitutively 59 IDH2 59 antisense RNA 59 MT1 MMP 59 glucose transporter 59 Pax6 59 myocyte enhancer factor 59 ERBB2 59 RKIP 59 nestin 59 DGAT1 59 heme oxygenase 1 59 V#F mutation 59 nucleolin 59 Protein Kinase C 59 SGLT2 59 BRAF gene 59 Macrophage 59 Myostatin 59 PDE#A 59 leptin receptor 59 melatonin receptor 59 eIF 4E 59 focal adhesion kinase FAK 59 microglial 59 kinesin 59 primary cilium 59 oncogenesis 59 neurotransmitter glutamate 59 endocytosis 59 cohesin 59 SCD1 59 VIPR2 59 TRPV3 59 signaling cascade 59 PIP3 59 BMAL1 59 homodimer 59 BDNF 59 HIF 1a 59 cytokine interleukin 59 Id1 59 PI3K Akt 59 myeloma cells 59 Akt pathway 59 signaling cascades 59 caspase activation 59 RAD# [001] 59 PDE5A 59 vascular endothelial 59 Sox9 59 torsinA 59 tRNA synthetase 59 CCL5 59 HSP# 59 antioxidant enzymes 59 osteoclast activity 59 noncoding RNAs 59 TLR4 59 reductase 59 CDK8 59 signal transduction pathways 59 p#Kip# 59 NKG2D 59 protein tyrosine kinase 59 Cyclin E 59 DHFR 59 factor GDNF 59 kinase PI3K 59 miR #b [001] 59 menin 59 N cadherin 59 SWI SNF 59 alpha catenin 59 osteoclast 59 tumor microenvironment 59 FasL 59 PPAR γ 59 transcriptional coactivator 59 anti angiogenic 59 protein tau 59 Inhibition 59 mutant huntingtin protein 59 kinase enzymes 59 non coding RNA 59 oncoproteins 59 cardiolipin 59 myeloid cells 59 susceptibility gene 59 TNF α 59 sphingolipid 59 cyclic AMP 59 5 hydroxymethylcytosine 59 neuregulin 59 Bcl 59 mRNAs 59 LDLR 59 fibroblast growth 59 TNF alpha 59 inhibitory effects 59 prognostic marker 59 Clusterin 59 cytosolic 59 APOBEC3G 59 mGluR 59 signaling molecules 59 mice lacking 59 Th2 59 MMP2 59 transcriptional repression 59 oxidative phosphorylation 59 cardiac hypertrophy 59 ApoE 59 IL# [001] 59 plasminogen 59 homodimers 59 Src kinase 59 inflammasome 59 phosphoinositide 3 59 alpha secretase 58 AT1R 58 FOXO1a 58 endostatin 58 SOCS1 58 Factor VEGF 58 astrocyte 58 Activating mutations 58 TNFalpha 58 HCV replication 58 membrane protein 58 FGF receptor 58 follistatin 58 CB1 receptor 58 microglial cells 58 JAK2 enzyme 58 epithelial mesenchymal transition 58 prostaglandin E2 PGE2 58 FMRP 58 FGFR 58 protein interleukin 58 potent inhibitors 58 gene locus 58 gluconeogenesis 58 HER1 58 GRP# 58 oncogenic signaling 58 neuronal cells 58 Ago2 58 TGFß 58 c Src 58 mitochondrial respiration 58 genes 58 bone resorption 58 superoxide 58 inflammatory cytokines 58 Dysregulation 58 glycolysis 58 histone deacetylase 58 VEGFb 58 factor EGF 58 VEGFR2 58 TNFa 58 intron 58 CDK5 58 Wnt beta catenin 58 protein phosphatase 58 ceramide 58 miR #b [002] 58 telomerase 58 Kinases 58 matrix metalloproteinases MMPs 58 cholesterol metabolism 58 β cells 58 small RNAs 58 substrate specificity 58 opioid receptor 58 PrP 58 nicotinamide 58 lymphotoxin 58 TIR1 58 cell adhesion 58 glycosylation 58 Epidermal Growth Factor 58 cannabinoid receptor 58 HER2 receptors 58 gene expression 58 mTOR mammalian target 58 TLR3 58 mesothelin 58 IL #E 58 CCR3 58 tumor antigen 58 adaptive immunity 58 hormone leptin 58 miR# 58 cytotoxic T lymphocytes 58 receptor gamma 58 secretase 58 histone deacetylase inhibitors 58 Rev erb 58 TSP1 58 nAChR 58 neuronal migration 58 histone acetylation 58 STK# [002] 58 hematopoiesis 58 MTHFR 58 DNA methylation 58 palmitoylation 58 BMP2 58 oxidase 58 kinase inhibitor 58 LSD1 58 Myb 58 Tregs 58 glycolipids 58 PI3K/Akt pathway 58 NF1 gene 58 ectopic expression 58 inhibitory effect 58 effector T 58 uPA 58 TRAIL induced apoptosis 58 PARP1 58 p# mutations 58 PPAR 58 Sonic hedgehog 58 transthyretin 58 huntingtin gene 58 CaMKII 58 TG2 58 sphingosine 1 58 TXNIP 58 metabolic pathway 58 astrocytes 58 IRF6 58 regulated kinase 58 Vascular endothelial growth 58 Wnt1 58 cilium 58 genotoxic stress 58 Hsp# [002] 58 inducible 58 mutational status 58 acetylcholinesterase 58 insulin secretion 58 chromosomal instability 58 pharmacological inhibition 58 adiponectin 58 Janus kinase 58 nuclease 58 fatty acid synthesis 58 naturally occurring enzyme 58 myocardin 58 glial cells 58 Sonic Hedgehog 58 podocytes 58 GluR1 58 PPAR delta 58 neurturin 58 endocannabinoid system 58 androgens 58 adrenergic receptors 58 SMN2 58 Tumor necrosis factor 58 NADPH oxidase 58 gp# [002] 58 Transcription Factor 58 malignant transformation 58 HMGA2 58 amyloid precursor protein 58 dephosphorylation 58 GGTase 58 bacterial enzyme 58 ACh 58 osteoblast 58 deacetylases 58 ZBP1 58 NF KB 58 prostaglandin synthesis 58 PKCi 58 upregulates 58 EphB2 58 TGF β1 58 erythropoietin receptor 58 AAV2 58 NF kappaB activation 58 paracrine